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Vaccine Megathread No 2 - Read OP before posting

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Comments

  • Posts: 0 [Deleted User]


    90% efficient doesn't mean you have only a 10% chance of ending up in hospital.

    I understand it to be 10% of your normal chance of ending up in hospital with it and am good with that


  • Registered Users, Registered Users 2 Posts: 32,136 ✭✭✭✭is_that_so


    Corholio wrote: »
    I'm guessing the 39-35 age group would not be until around late June now? Have they released any sort of estimate timeline at all?
    You can guess at it - Over 50s done by mid-June, then a decent chunk of the over 40s by the end of June. The 35-39 group should register after June BH with shots starting near the end of the month.


  • Registered Users, Registered Users 2 Posts: 877 ✭✭✭eoinbn


    Cloudio9 wrote: »
    It gets slower now because all the people who got Pfizer and Modena in the May ramp up need second doses in June.(assuming we continue at the 250-300k rate)

    Supply increases to ~310k-315k mRNA doses weekly in June. We should be able to use 170k-200k as first doses. However we are due to give ~150k second doses of AZ to young healthcare workers who might be given mRNA instead.

    On that basis it will be the middle of July before we hit 80%.


  • Registered Users, Registered Users 2 Posts: 14,014 ✭✭✭✭Corholio


    is_that_so wrote: »
    You can guess at it - Over 50s done by mid-June, then a decent chunk of the over 40s by the end of June. The 35-39 group should register after June BH with shots starting near the end of the month.

    Thanks for the guess at it. You think they'd be registering that early (after Bank Holiday) in the month for 35-39?


  • Registered Users, Registered Users 2 Posts: 32,136 ✭✭✭✭is_that_so


    Corholio wrote: »
    Thanks for the guess at it. You think they'd be registering that early (after Bank Holiday) in the month for 35-39?
    Based on the progress so far it seems about right.


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  • Registered Users, Registered Users 2 Posts: 15,443 ✭✭✭✭stephenjmcd


    eoinbn wrote: »
    Supply increases to ~310k-315k mRNA doses weekly in June. We should be able to use 170k-200k as first doses. However we are due to give ~150k second doses of AZ to young healthcare workers who might be given mRNA instead.

    On that basis it will be the middle of July before we hit 80%.

    They're still giving AZ as dose 2 regardless of age.

    Friend of mine, 27 year old nurse got an apointment yesterday for an MVC next week, AZ dose 2. 12 weeks after first, didn't expect it until 16 weeks but NIAC advice changed


  • Registered Users, Registered Users 2 Posts: 17,432 ✭✭✭✭astrofool


    Yes there's a large misunderstanding really when the word effective is used.

    I don't think most of the public really understand what is meant by efficency of the vaccine but that's the fault of the reporting on such.

    And we have another page spent on a misunderstanding of what the study says :)

    Really, the only conclusion that can be made from the study is that following the dosing schedule of AZ and Pfizer gives a fantastic response to different variants of SARS-COV2, there just isn't the data to say anything else (and the data reported doesn't control for when a vaccine was given, how many weeks from 1st dose there were effects, what the symptoms of those infected were etc.). Given these are 2 dose vaccines there will not be data on what happens if the 2nd dose isn't taken.


  • Registered Users, Registered Users 2 Posts: 43 suttonboi1


    Been out of the loop on this thread over the past week, but do we have any indication of total vaccinated at this stage, and make up of first, second and one dose shots?


  • Registered Users, Registered Users 2 Posts: 8,054 ✭✭✭Fann Linn


    How are the vaccines allocated? Is it a case of whatever lands at Dublin Airport is simply shipped around the country? I'm asking as yesterday I received Pfizer at a Vaccination centre and only a few weeks back some workmates got AZ at the same one?
    Just curious!


  • Registered Users, Registered Users 2 Posts: 11,655 ✭✭✭✭salmocab


    Fann Linn wrote: »
    How are the vaccines allocated? Is it a case of whatever lands at Dublin Airport is simply shipped around the country? I'm asking as yesterday I received Pfizer at a Vaccination centre and only a few weeks back some workmates got AZ at the same one?
    Just curious!

    It’s a logistics exercise based on what’s available and what’s needed. So 4 weeks after your Pfizer jab Pfizer needs to be available from the same place. Then that day they will administer more Pfizer first jabs so another 4 weeks that needs to get more etc etc.


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  • Registered Users, Registered Users 2 Posts: 745 ✭✭✭ClosedAccountFuzzy


    Goldengirl wrote: »
    If that was the case they should ask the whole population to register within a week ?! :)

    It's about managing supplies and appointment dates , with some degree of organisation and least wait from registration as possible
    Large numbers in 40 to 49 year age group.
    They are probably learning from the delays that occurred with the older age groups also which is as it should be .

    It's still just a queue. Whether you've registered them online and have the data or don't is somewhat irrelevant. They'll have to wait until they're called one way or the other.

    I can appreciate slowing it to avoid the IT systems overloading, but it's all cloud based so it's also sort of irrelevant.


  • Registered Users, Registered Users 2 Posts: 6,627 ✭✭✭Micky 32




  • Registered Users, Registered Users 2 Posts: 11,203 ✭✭✭✭hmmm


    Micky 32 wrote: »
    This sounds like incredibly good news - is it?


  • Registered Users, Registered Users 2 Posts: 1,318 ✭✭✭Sammy2012


    Is there any talk of opening the vaccine portal for the rest of the 40s yet? I'm eagerly awaiting mine but need them to open the 35 to 39 age group first. So interested to see will I have my 1st dose by the end of June


  • Registered Users, Registered Users 2 Posts: 5,576 ✭✭✭JTMan


    HSE indicates people in 40s will not get AstraZeneca or Janssen vaccines, The Irish Times reports here.


  • Registered Users, Registered Users 2 Posts: 48,440 ✭✭✭✭km79


    JTMan wrote: »
    HSE indicates people in 40s will not get AstraZeneca or Janssen vaccines, The Irish Times reports here.

    Interesting


  • Registered Users, Registered Users 2 Posts: 2,276 ✭✭✭IRISHSPORTSGUY


    JTMan wrote: »
    HSE indicates people in 40s will not get AstraZeneca or Janssen vaccines, The Irish Times reports here.

    I don't know why we have to make this so complicated. Let the people decide, all adults, if they want to opt in for AZ or Janssen like in Germany and Belgium.


  • Registered Users, Registered Users 2 Posts: 17,299 ✭✭✭✭Sleeper12


    JTMan wrote:
    HSE indicates people in 40s will not get AstraZeneca or Janssen vaccines, The Irish Times reports


    It's unlikely anyone will be getting AZ except if they have already had a first dose of it. J&J delivery is way down so unlikely to be offered to under 50s


  • Registered Users, Registered Users 2 Posts: 62 ✭✭Teothican


    so i am 40 and i am wondering will i get just the 1 dose or will i be brought back 12 weeks later for a second one?


  • Registered Users, Registered Users 2 Posts: 48,440 ✭✭✭✭km79


    Teothican wrote: »
    so i am 40 and i am wondering will i get just the 1 dose or will i be brought back 12 weeks later for a second one?

    Depends on what vaccine you get !


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  • Registered Users, Registered Users 2 Posts: 11,655 ✭✭✭✭salmocab


    Teothican wrote: »
    so i am 40 and i am wondering will i get just the 1 dose or will i be brought back 12 weeks later for a second one?

    Almost certainly 2 doses 4 weeks apart


  • Registered Users, Registered Users 2 Posts: 5,175 ✭✭✭angeldelight


    Teothican wrote: »
    so i am 40 and i am wondering will i get just the 1 dose or will i be brought back 12 weeks later for a second one?

    It’s looking likely that you’ll be offered Pfizer or Moderna with the second dose 4 weeks later


  • Registered Users, Registered Users 2 Posts: 6,627 ✭✭✭Micky 32


    hmmm wrote: »
    This sounds like incredibly good news - is it?

    I really hope so, i’m losing faith by the day that vaccines will bring us out of this awful horrible situation :o


  • Registered Users, Registered Users 2 Posts: 11,203 ✭✭✭✭hmmm


    Micky 32 wrote: »
    I really hope so, i’m losing faith by the day that vaccines will bring us out of this awful horrible situation :o
    There isn't a single variant the vaccines can't cope with, we're in a great place. The only concern appears to be that we let our guard down before enough people are vaccinated, and there is a big surge in infection in unvaccinated groups.


  • Registered Users, Registered Users 2 Posts: 15,939 ✭✭✭✭Goldengirl


    Micky 32 wrote: »
    I really hope so, i’m losing faith by the day that vaccines will bring us out of this awful horrible situation :o

    It is good news , M
    Just saying on the other thread about the effect of T Cells being ignored in these studies.
    Even with some with just one dose so far healthcare workers infections have gone through the floor so T Cell immunity must be playing a part there .


  • Registered Users, Registered Users 2 Posts: 17,299 ✭✭✭✭Sleeper12


    hmmm wrote:
    There isn't a single variant the vaccines can't cope with, we're in a great place. The only concern appears to be that we let our guard down before enough people are vaccinated, and there is a big surge in infection in unvaccinated groups.


    Id love to see stats for J&J. I wonder will a 2nd dose be required for the India strain


  • Registered Users, Registered Users 2 Posts: 15,939 ✭✭✭✭Goldengirl


    Sleeper12 wrote: »
    Id love to see stats for J&J. I wonder will a 2nd dose be required for the India strain

    Or a Pfizer booster ?


  • Posts: 0 [Deleted User]


    I think t cells are very important for short/long term immunity.

    Antibodies are merely a by product of t-cell immunity.

    I'd imagine one dose of any vaccine will avoid majority of serious illnesses for average Joe & Mary.

    The reason this virus is dangerous to our species is that its novel.

    Vaccination means its no longer novel to your body.

    Once your vaccinated and a month has passed the chance of you going to hospital is probably miniscule unless your very vulnerable (vulnerable people die of the flu each year).

    I dont't always agree with Philip Nolan, but he kind of said the above with comparing vaccines this week.

    All vaccines do what we want them to do, avoid serious illness. I agree with him.

    All currently approved vaccines will likely stop you going to hospital (one dose or two).

    All offer good individual protection in the first instance.

    Variants and transmission is a work in progress for all available vaccines.

    You also wonder at the quality of this data re: indian variant in UK first dose/second dose debate.

    Someone could have been infected two weeks after first pfzier or astra.

    Your obviously going to be more protected after two doses of a vaccine than up to say a few weeks after first vaccine.

    Your immunity is more mature.

    Are they excluding people infected who were only vaxxed a few weeks with their first dose in the data?

    Israel data said these lads (people post first vax 0 to 3 weeks) were twice as likely to be infected because they naturally let their guard down ever so slightly.

    Everyone knows these guys have next to no immunity.


  • Registered Users, Registered Users 2 Posts: 11,203 ✭✭✭✭hmmm


    Sleeper12 wrote: »
    Id love to see stats for J&J. I wonder will a 2nd dose be required for the India strain
    The recent findings out of the UK suggest that the Indian strain isn't as bad as the South African variant for vaccine effectiveness, and the J&J vaccine showed good results in the South African arm of the trial. So that's hopeful.


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  • Closed Accounts Posts: 4,550 ✭✭✭ShineOn7


    Are there any real differences between the mRNA vaccines Pfizer and Moderna?

    I've had a read on the HSE website and can't see any major ones

    All info from here https://www2.hse.ie/screening-and-vaccinations/covid-19-vaccine/

    Efficiency:

    Pfizer - 95%
    Moderna - 94%

    Side effects:

    Both appear to be practically the same too with negligible side effects. Although for both the HSE website mentions "More than 1 in 10,000 people may develop Bell’s palsy"

    BP is usually temporary as far as I know


    Other:

    Both have a 4 week gap for the second shot

    With Pfizer you're good to go a week after this and Moderna is two weeks after

    Happy days

    Indian variant:
    The Pfizer/BioNTech and Moderna coronavirus vaccines appear to protect against COVID variants B.1.617 and B.1.618 first identified in India, researchers have reported in a new pre-print paper, which has not yet been peer-reviewed, CNN reported
    https://www.business-standard.com/article/current-affairs/pfizer-moderna-vaccines-effective-against-covid-variants-from-india-study-121051800070_1.html

    More good news there

    Miscellaneous:
    New evidence

    New evidence from Israel shows the risk of severe COVID-19 was reduced by 92%, 7 days after 2 doses of the Pfizer/BioNTech vaccine.

    https://www2.hse.ie/screening-and-vaccinations/covid-19-vaccine/pfizer-biontech/immunity/

    It's looking like almost all (if not all) 40-49 year olds in Ireland will get one of these two vaccines so I thought it'd be good to jump into the data

    TLDR: On reading the information I've found, they seem to be pretty much the same Vaccine


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