COVID-19: Vaccine and testing procedures Megathread Part 3 - Read OP

stephenjmcd · 07-03-2021 11:22AM

JTMan wrote: »

Sunday Independent reports here that the Irish government is considering Russia's Sputnik vaccine.

Although there are doubts about Russia's ability to manufacture large numbers of doses ... a German company, IDT Biologika, is in talks about producing the Sputnik V vaccine.

Small additional supply from Sputnik on the way?

Separately, the Sunday Independent reports that the government has been unable to secure extra vaccine doses from elsewhere, despite approaches over recent days to a number of countries and pharma companies who have a presence in Ireland.

Clearly states it'll be used if approved by EMA, not much of a story there. Like every other vaccine if approved by the EMA they'll use it

Deusexmachina · 07-03-2021 11:33AM

Whats the latest with the J&J vaccine? Has it received EMA approval yet? Can it be manufactured at a volume that will help us? When is that likely to happen?

is_that_so · 07-03-2021 11:36AM

Deusexmachina wrote: »

Whats the latest with the J&J vaccine? Has it received EMA approval yet? Can it be manufactured at a volume that will help us? When is that likely to happen?

No, Thursday, April.

Deusexmachina · 07-03-2021 11:41AM

is_that_so wrote: »

No, Thursday, April.

Thanks. Have we any idea of the likely volume of manufacture? Have they indicated any numbers. Can I get my feckin hopes up?

ACitizenErased · 07-03-2021 11:41AM

https://twitter.com/covid19dataie/status/1368509737453690881?s=21

07-03-2021 11:46AM

ACitizenErased wrote: »

https://twitter.com/covid19dataie/status/1368509737453690881?s=21

Is that the highest day so far?

is_that_so · 07-03-2021 11:48AM

Deusexmachina wrote: »

Thanks. Have we any idea of the likely volume of manufacture? Have they indicated any numbers. Can I get my feckin hopes up?

The EU order is for 200m, with an option of a further 200m. Once logistics are sorted out we should hear exact numbers and when. Early April is the loose date for the start of deliveries.

trellheim · 07-03-2021 11:51AM

ACitizenErased wrote: »

https://twitter.com/covid19dataie/status/1368509737453690881?s=21

Yes previous highest no of shots 18174 on 25 feb

ACitizenErased · 07-03-2021 11:51AM

Definitive prove of AZ efficacy - 81% after a 12 week interval
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)00528-6/fulltext

Deusexmachina · 07-03-2021 11:52AM

is_that_so wrote: »

The EU order is for 200m, with an option of a further 200m. Once logistics are sorted out we should hear exact numbers and when. Early April is the loose date for the start of deliveries.

Thanks again. Yes, I read we have 2.2 million of the European order.
I am concerned about the production capability. Hope it's not another Moderna or AZ where production cannot meet volumes required.

Any idea on that anyone?

is_that_so · 07-03-2021 11:55AM

Deusexmachina wrote: »

Thanks again. Yes, I read we have 2.2 million of the European order.
I am concerned about the production capability. Hope it's not another Moderna or AZ where production cannot meet volumes required.

Any idea on that anyone?

Merck will make it for them in the US and they are vaccine makers, unlike the other two. Being single shot eases that risk considerably.

Deusexmachina · 07-03-2021 11:57AM

is_that_so wrote: »

Merck will make it for them in the US and they are vaccine makers, unlike the other two. Being single shot eases that risk considerably.

Good stuff. Thanks. Assume we could make it here? (MSD is very substantial here).

Apogee · 07-03-2021 12:06PM

Apogee wrote: »

Wed No: 13,354 administered.

71,927 in Cohort 3 - even allowing for them also starting with the over 80's on Monday, they seem to be on track to have the majority of over 85's (72,000) done by the end of the week. It might even have turned out to be a good thing logistically to have opted for mRNA vaccines for over 70s given the lumpiness in the AZ supply currently.

There are still increases in Dose 1 numbers for Cohort 1, so apparently not yet complete.

83,394 last week vs target of 100,000. Likely 84,000 this week vs target of 95,000. Shortfall of approx 27K which is in line with delayed delivery of 25K AZ.

Re: efforts to source extra vaccines

https://www.irishtimes.com/news/health/coronavirus/covid-19-government-likely-to-miss-target-of-issuing-1-25m-vaccines-by-end-of-march-1.4502674

Thursday No: 18,709 (highest one day). Large chunk of which are Cohort 3 - approx 10K.

Marhay70 · 07-03-2021 12:06PM

I haven't seen it on here but I read that Moderna are also likely to fall short by 15% on deliveries this month. I can't see confirmation of this in the media.

brickster69 · 07-03-2021 12:16PM

Australia receives it's missing doses

https://www.msn.com/en-au/news/other/british-authorities-help-australia-access-vaccines-after-italy-astrazeneca-export-ban/ar-BB1ejQMo?ocid=st

Tippbhoy1 · 07-03-2021 12:17PM

Deusexmachina wrote: »

Good stuff. Thanks. Assume we could make it here? (MSD is very substantial here).

Interesting point ..... they do have a facility for vaccines in Carlow reading here...good ole Ireland might get a chance to contribute yet. I do think it takes months to get up and running though with all the validation required. We will have to see.

Re volume planned, closest info I read somewhere was 100m by June for the EU. This did involve sending some from Holland to the USA for fill and finish mind you, so that could create an issue. Either way, I’d say half the estimate by end June would be a good figure to go with, so half a mill for Ireland by the end of June, for a single shot would be my guesstimate.

Apogee · 07-03-2021 12:26PM

Marhay70 wrote: »

I haven't seen it on here but I read that Moderna are also likely to fall short by 15% on deliveries this month. I can't see confirmation of this in the media.

https://twitter.com/newschambers/status/1368331292459339786

Here are the original supply forecasts:

As of 4th March vs target for March 31st/Q1:
Pfizer 397,409/690,300 = 57%
Moderna 12,863/109,200 = 11%
AZ 83,601/449,028 = 18%

ninebeanrows · 07-03-2021 12:33PM

brickster69 wrote: »

Australia receives it's missing doses

https://www.msn.com/en-au/news/other/british-authorities-help-australia-access-vaccines-after-italy-astrazeneca-export-ban/ar-BB1ejQMo?ocid=st

Wow the UK really giving the two fingers to the EU

I guess it's probably their only power play left before the head into post brexit wildnerness

mandrake04 · 07-03-2021 12:35PM

Marhay70 wrote: »

I haven't seen it on here but I read that Moderna are also likely to fall short by 15% on deliveries this month. I can't see confirmation of this in the media.

https://www.independent.ie/world-news/coronavirus/new-setback-for-covid-19-vaccination-as-roll-out-to-over-80s-hit-due-to-moderna-jab-shortfall-40167770.html?utm_source=facebook&utm_medium=social&utm_campaign=seeding&fbclid=IwAR1jztNzdD_CNjRXf5ShNaLOns6eSC2v4WWv-_M6oi1-Bzw2_VUvdkp6_M0

Renault 5 · 07-03-2021 12:51PM

ninebeanrows wrote: »

Wow the UK really giving the two fingers to the EU

I guess it's probably their only power play left before the head into post brexit wildnerness

I don’t blame the UK.
I would think they will say it’s due to the commonwealth.

Canada will be next up to receive vaccines from the UK I would think.

is_that_so · 07-03-2021 01:07PM

Renault 5 wrote: »

I don’t blame the UK.
I would think they will say it’s due to the commonwealth.

Canada will be next up to receive vaccines from the UK I would think.

The Australian situation was down to it being deemed to be of low immediate need. Canada would be more deserving on account of their cases but they have also put in a request for vaccines from COVAX, not exactly shining 1st world behaviour.

timsey tiger · 07-03-2021 01:07PM

Renault 5 wrote: »

I don’t blame the UK.
I would think they will say it’s due to the commonwealth.

Canada will be next up to receive vaccines from the UK I would think.

Then I guess you would also support the EU in banning any vaccine exports until the EU has what it needs.

is_that_so · 07-03-2021 01:13PM

mandrake04 wrote: »

https://www.independent.ie/world-news/coronavirus/new-setback-for-covid-19-vaccination-as-roll-out-to-over-80s-hit-due-to-moderna-jab-shortfall-40167770.html?utm_source=facebook&utm_medium=social&utm_campaign=seeding&fbclid=IwAR1jztNzdD_CNjRXf5ShNaLOns6eSC2v4WWv-_M6oi1-Bzw2_VUvdkp6_M0

The total Moderna footprint here is very small at about 3% of Pfizer. The missing/delayed AZ shots from this last week or so are double its overall total. It was always going to be way smaller until Q2/Q3 bring supplies up.

josip · 07-03-2021 01:13PM

AdamD wrote: »

Is Sputnik not a bit of a red herring? I don't see Russia at the top of these vaccination tables so where are the excess doses they're going to sell us?

They're either giving higher priority to the political PR than their own citizens OR their own citizens don't trust the vaccine.

JTMan · 07-03-2021 01:24PM

A simple strategy for GPs when patients refuse to get a vaccine ... Call and ask why ...

https://twitter.com/drmarkporter/status/1368494757530509315?s=19

is_that_so · 07-03-2021 01:31PM

josip wrote: »

They're either giving higher priority to the political PR than their own citizens OR their own citizens don't trust the vaccine.

Well, they did declare it a success in the middle of the clinical trial. Some of that early testing was researchers injecting themselves!

mandrake04 · 07-03-2021 01:49PM

is_that_so wrote: »

The Australian situation was down to it being deemed to be of low immediate need. Canada would be more deserving on account of their cases but they have also put in a request for vaccines from COVAX, not exactly shining 1st world behaviour.

From an Australian point of view it’s no big deal, its not even that big a story here it’s not even a bump in the road.

But a deal is a deal and the bigger picture Australia is committed to help its smaller neighbours in the south Pacific as soon as it’s done

“That is why, arguably, one of the two most important decisions we’ve made throughout the pandemic was to contract for the supply of 50 million doses of Australian-made sovereign manufactured CSL AstraZeneca product in Australia.”

Australia has so far had 743,000 doses delivered, including 443,000 of Pfizer’s
drug and 300,000 from AstraZeneca.

The government expects another 149,000 Pfizer doses to be delivered in the next
fortnight, before the first of 51 million locally-made doses of AstraZeneca vaccine
begin to be supplied, at a rate of one million a week.

The EU export mechanism is designed to ensure doses made in the EU are first
devoted to servicing Europe. It was brought in after a big brawl between Brussels
and AstraZeneca in January, when the European Commission accused the
company of failing to fulfil its supply contract and favouring other nations.

Mr Hunt said some states had sufficient capacity to move to phase 1B of their
rollout strategies.

is_that_so · 07-03-2021 01:52PM

A report from last week on J&J production issues, which seem to have been sorted now.

https://www.irishtimes.com/business/health-pharma/johnson-johnson-s-us-vaccine-rollout-slowed-by-production-problems-1.4498049

hmmm · 07-03-2021 01:53PM

mandrake04 wrote: »

From an Australian point of view it’s no big deal, its not even that big a story here it’s not even a bump in the road.

But a deal is a deal and the bigger picture Australia is committed to help its smaller neighbours in the south Pacific as soon as it’s done

Yeah, I don't like this at all and it's not something to be proud of.

It's also a good indication as to what may have happened in Europe if everyone had gone their own way. The Germans were stopping the export of ventilators to Italy in the beginning, you think they'd have not kept every Pfizer vaccine for themselves if they could?

Micky 32 · 07-03-2021 01:53PM

https://twitter.com/laoneill111/status/1368269971340529668?s=21

COVID-19: Vaccine and testing procedures Megathread Part 3 - Read OP

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