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COVID-19: Vaccine and testing procedures Megathread Part 3 - Read OP

Beasty

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Thread 2

No anti-vax stuff in this thread - it's to discuss the various vaccines available and how they are getting rolled out, as well as testing procedures

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snotboogie

Israel have reached 100 vaccines doses per 100 people.

is_that_so

Renault 5 wrote: »

Weather I support it or not, they seem to be doing it anyway until the order which was agreed is delivered.

Whether the weather is warm, whether the weather is hot, we have to put up with the weather, whether we like it or not!

Renault 5

timsey tiger wrote: »

Then I guess you would also support the EU in banning any vaccine exports until the EU has what it needs.

Whether I support it or not, they seem to be doing it anyway until the order which was agreed is delivered.

mick087

JTMan wrote: »

A simple strategy for GPs when patients refuse to get a vaccine ... Call and ask why ...

https://twitter.com/drmarkporter/status/1368494757530509315?s=19

That's a big uptake of non takers 70% after a simple phone call.
Sounds like it a really good idea.

hmmm

AdamD wrote: »

Maybe I'm being cynical but I can't see countries dishing out their excess doses anytime soon - i.e. the idea that Ireland or Canada will be getting doses from the UK. The last few % of people will take a while to vaccinate and I think countries will be pretty reluctant to give up doses whilst they're unsure of the need for boosters etc.

By the time they're ready to give anything away we'll probably not need any

Absolutely, but that doesn't pay the salaries for those proposing simplistic solutions in newspaper articles ("Sputnik", "let's just get their spare doses", "buy some more"). I'm surprised no-one has proposed nationalising a pharmaceutical plant or some creamery somewhere and start manufacturing an indigenous vaccine.

[Deleted User]

Maybe I'm being cynical but I can't see countries dishing out their excess doses anytime soon - i.e. the idea that Ireland or Canada will be getting doses from the UK. The last few % of people will take a while to vaccinate and I think countries will be pretty reluctant to give up doses whilst they're unsure of the need for boosters etc.

By the time they're ready to give anything away we'll probably not need any

Micky 32

https://twitter.com/laoneill111/status/1368269971340529668?s=21

hmmm

mandrake04 wrote: »

From an Australian point of view it’s no big deal, its not even that big a story here it’s not even a bump in the road.

But a deal is a deal and the bigger picture Australia is committed to help its smaller neighbours in the south Pacific as soon as it’s done

Yeah, I don't like this at all and it's not something to be proud of.

It's also a good indication as to what may have happened in Europe if everyone had gone their own way. The Germans were stopping the export of ventilators to Italy in the beginning, you think they'd have not kept every Pfizer vaccine for themselves if they could?

is_that_so

A report from last week on J&J production issues, which seem to have been sorted now.

https://www.irishtimes.com/business/health-pharma/johnson-johnson-s-us-vaccine-rollout-slowed-by-production-problems-1.4498049

mandrake04

is_that_so wrote: »

The Australian situation was down to it being deemed to be of low immediate need. Canada would be more deserving on account of their cases but they have also put in a request for vaccines from COVAX, not exactly shining 1st world behaviour.

From an Australian point of view it’s no big deal, its not even that big a story here it’s not even a bump in the road.

But a deal is a deal and the bigger picture Australia is committed to help its smaller neighbours in the south Pacific as soon as it’s done

“That is why, arguably, one of the two most important decisions we’ve made throughout the pandemic was to contract for the supply of 50 million doses of Australian-made sovereign manufactured CSL AstraZeneca product in Australia.”

Australia has so far had 743,000 doses delivered, including 443,000 of Pfizer’s
drug and 300,000 from AstraZeneca.

The government expects another 149,000 Pfizer doses to be delivered in the next
fortnight, before the first of 51 million locally-made doses of AstraZeneca vaccine
begin to be supplied, at a rate of one million a week.

The EU export mechanism is designed to ensure doses made in the EU are first
devoted to servicing Europe. It was brought in after a big brawl between Brussels
and AstraZeneca in January, when the European Commission accused the
company of failing to fulfil its supply contract and favouring other nations.

Mr Hunt said some states had sufficient capacity to move to phase 1B of their
rollout strategies.

is_that_so

josip wrote: »

They're either giving higher priority to the political PR than their own citizens OR their own citizens don't trust the vaccine.

Well, they did declare it a success in the middle of the clinical trial. Some of that early testing was researchers injecting themselves!

JTMan

A simple strategy for GPs when patients refuse to get a vaccine ... Call and ask why ...

https://twitter.com/drmarkporter/status/1368494757530509315?s=19

josip

AdamD wrote: »

Is Sputnik not a bit of a red herring? I don't see Russia at the top of these vaccination tables so where are the excess doses they're going to sell us?

They're either giving higher priority to the political PR than their own citizens OR their own citizens don't trust the vaccine.

is_that_so

mandrake04 wrote: »

https://www.independent.ie/world-news/coronavirus/new-setback-for-covid-19-vaccination-as-roll-out-to-over-80s-hit-due-to-moderna-jab-shortfall-40167770.html?utm_source=facebook&utm_medium=social&utm_campaign=seeding&fbclid=IwAR1jztNzdD_CNjRXf5ShNaLOns6eSC2v4WWv-_M6oi1-Bzw2_VUvdkp6_M0

The total Moderna footprint here is very small at about 3% of Pfizer. The missing/delayed AZ shots from this last week or so are double its overall total. It was always going to be way smaller until Q2/Q3 bring supplies up.

is_that_so

Renault 5 wrote: »

I don’t blame the UK.
I would think they will say it’s due to the commonwealth.

Canada will be next up to receive vaccines from the UK I would think.

The Australian situation was down to it being deemed to be of low immediate need. Canada would be more deserving on account of their cases but they have also put in a request for vaccines from COVAX, not exactly shining 1st world behaviour.

timsey tiger

Renault 5 wrote: »

I don’t blame the UK.
I would think they will say it’s due to the commonwealth.

Canada will be next up to receive vaccines from the UK I would think.

Then I guess you would also support the EU in banning any vaccine exports until the EU has what it needs.

Renault 5

ninebeanrows wrote: »

Wow the UK really giving the two fingers to the EU

I guess it's probably their only power play left before the head into post brexit wildnerness

I don’t blame the UK.
I would think they will say it’s due to the commonwealth.

Canada will be next up to receive vaccines from the UK I would think.

mandrake04

Marhay70 wrote: »

I haven't seen it on here but I read that Moderna are also likely to fall short by 15% on deliveries this month. I can't see confirmation of this in the media.

https://www.independent.ie/world-news/coronavirus/new-setback-for-covid-19-vaccination-as-roll-out-to-over-80s-hit-due-to-moderna-jab-shortfall-40167770.html?utm_source=facebook&utm_medium=social&utm_campaign=seeding&fbclid=IwAR1jztNzdD_CNjRXf5ShNaLOns6eSC2v4WWv-_M6oi1-Bzw2_VUvdkp6_M0

ninebeanrows

brickster69 wrote: »

Australia receives it's missing doses

https://www.msn.com/en-au/news/other/british-authorities-help-australia-access-vaccines-after-italy-astrazeneca-export-ban/ar-BB1ejQMo?ocid=st

Wow the UK really giving the two fingers to the EU

I guess it's probably their only power play left before the head into post brexit wildnerness

Apogee

Marhay70 wrote: »

I haven't seen it on here but I read that Moderna are also likely to fall short by 15% on deliveries this month. I can't see confirmation of this in the media.

https://twitter.com/newschambers/status/1368331292459339786

Here are the original supply forecasts:

As of 4th March vs target for March 31st/Q1:
Pfizer 397,409/690,300 = 57%
Moderna 12,863/109,200 = 11%
AZ 83,601/449,028 = 18%

Tippbhoy1

Deusexmachina wrote: »

Good stuff. Thanks. Assume we could make it here? (MSD is very substantial here).

Interesting point ..... they do have a facility for vaccines in Carlow reading here...good ole Ireland might get a chance to contribute yet. I do think it takes months to get up and running though with all the validation required. We will have to see.

Re volume planned, closest info I read somewhere was 100m by June for the EU. This did involve sending some from Holland to the USA for fill and finish mind you, so that could create an issue. Either way, I’d say half the estimate by end June would be a good figure to go with, so half a mill for Ireland by the end of June, for a single shot would be my guesstimate.

brickster69

Australia receives it's missing doses

https://www.msn.com/en-au/news/other/british-authorities-help-australia-access-vaccines-after-italy-astrazeneca-export-ban/ar-BB1ejQMo?ocid=st

Marhay70

I haven't seen it on here but I read that Moderna are also likely to fall short by 15% on deliveries this month. I can't see confirmation of this in the media.

Apogee

Apogee wrote: »

Wed No: 13,354 administered.

71,927 in Cohort 3 - even allowing for them also starting with the over 80's on Monday, they seem to be on track to have the majority of over 85's (72,000) done by the end of the week. It might even have turned out to be a good thing logistically to have opted for mRNA vaccines for over 70s given the lumpiness in the AZ supply currently.

There are still increases in Dose 1 numbers for Cohort 1, so apparently not yet complete.

83,394 last week vs target of 100,000. Likely 84,000 this week vs target of 95,000. Shortfall of approx 27K which is in line with delayed delivery of 25K AZ.

Re: efforts to source extra vaccines

https://www.irishtimes.com/news/health/coronavirus/covid-19-government-likely-to-miss-target-of-issuing-1-25m-vaccines-by-end-of-march-1.4502674

Thursday No: 18,709 (highest one day). Large chunk of which are Cohort 3 - approx 10K.

Deusexmachina

is_that_so wrote: »

Merck will make it for them in the US and they are vaccine makers, unlike the other two. Being single shot eases that risk considerably.

Good stuff. Thanks. Assume we could make it here? (MSD is very substantial here).

is_that_so

Deusexmachina wrote: »

Thanks again. Yes, I read we have 2.2 million of the European order.
I am concerned about the production capability. Hope it's not another Moderna or AZ where production cannot meet volumes required.

Any idea on that anyone?

Merck will make it for them in the US and they are vaccine makers, unlike the other two. Being single shot eases that risk considerably.

Deusexmachina

is_that_so wrote: »

The EU order is for 200m, with an option of a further 200m. Once logistics are sorted out we should hear exact numbers and when. Early April is the loose date for the start of deliveries.

Thanks again. Yes, I read we have 2.2 million of the European order.
I am concerned about the production capability. Hope it's not another Moderna or AZ where production cannot meet volumes required.

Any idea on that anyone?

ACitizenErased

Definitive prove of AZ efficacy - 81% after a 12 week interval
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)00528-6/fulltext

trellheim

ACitizenErased wrote: »

https://twitter.com/covid19dataie/status/1368509737453690881?s=21

Yes previous highest no of shots 18174 on 25 feb

is_that_so

Deusexmachina wrote: »

Thanks. Have we any idea of the likely volume of manufacture? Have they indicated any numbers. Can I get my feckin hopes up?

The EU order is for 200m, with an option of a further 200m. Once logistics are sorted out we should hear exact numbers and when. Early April is the loose date for the start of deliveries.