COVID-19: Vaccine and testing procedures Megathread Part 3 - Read OP

Gael23 · 25-02-2021 03:33PM

What’s the story with Valneva? Never heard of them until recently

25-02-2021 03:35PM

Sweet.Science wrote: »

How do you have 38 close contacts with 72 hours at any stage of your life

Nevermind during a pandemic

Outside of a pandemic its really not difficult to envisage at all

During a pandemic yeah its a bit mad

hmmm · 25-02-2021 03:36PM

Deleted User wrote: »

Very wide confidence interval on the disappointing data, but realistically we should be covering vulnerable groups with Pfizer and moderna with a first dose by the time any j and j is available so might be best just to use it on under 60s anyhow

We've been a little bit spoiled by the two-dose mRNA vaccines

In fairness to J&J, they are the only company which said "let's see if we can get a decent result with just one vaccine" and stuck their neck out to do so - knowing that the world needed an easy-to-administer single dose vaccine.

Agreed that it looks like it won't be given to the super-vulnerable, but it appears a good option for use in the general population - I'd be more than happy to get it. J&J have also hedged their bets of course by running the two-dose trial.

stephenjmcd · 25-02-2021 03:36PM

Only 1 way of looking at this, has to be vaccination

https://twitter.com/newschambers/status/1364947074425499652?s=20

irishlad. · 25-02-2021 03:38PM

That graph on the right is easy on the eyes

Deeper Blue · 25-02-2021 03:42PM

brickster69 wrote: »

FDA data for J&J

https://twitter.com/AlexBerenson/status/1364911005818621954

I thought there were articles yesterday saying it was very effective?

The guy that tweeted that is a covid denying clown so I'm assuming whatever he's pointing out is fairly selective.

KrustyUCC · 25-02-2021 03:43PM

GPs having to call patients to cancel vaccinations as supply hasn't reached the practice

I really hope these issues get smoothed out as if we're having issues trying to sort 100,000 vaccines a week those issues could be multiplied when we're trying to get 250,000 or 300,000 a week done

Gael23 · 25-02-2021 04:02PM

Pfizer supposed to be trialling a 3 dose regime to ward off new variants

Hmmzis · 25-02-2021 04:21PM

brickster69 wrote: »

FDA data for J&J

https://twitter.com/AlexBerenson/status/1364911005818621954

That table is for all primary endpoint cases including ones they did not confirm themselves. That data set is very noisy and comes with tons of caveats, the 14 day efficacy is at 65% while at 28 days it's 42% with massive CIs, there simply isn't enough data to get anything meaningful splitting it up like that. The same issue is with other subgroups as well, the trial simply hasn't ran long enough to make the CIs any narrower (or should we think now that it's 100% effective in asthma patients?).

is_that_so · 25-02-2021 04:23PM

KrustyUCC wrote: »

GPs having to call patients to cancel vaccinations as supply hasn't reached the practice

I really hope these issues get smoothed out as if we're having issues trying to sort 100,000 vaccines a week those issues could be multiplied when we're trying to get 250,000 or 300,000 a week done

When you say GPs, how many is that - 2 or 50?

ACitizenErased · 25-02-2021 04:24PM

HSE estimates of the new group 4
Total - 140,000
Cancer patients, renal patients & those who are immunocompromised (extremely high risk) - 42,000 of the 140,000

landofthetree · 25-02-2021 04:27PM

https://twitter.com/MayoClinic/status/1364959560805605377

Sconsey · 25-02-2021 04:32PM

ACitizenErased wrote: »

HSE estimates of the new group 5
Total - 140,000
Cancer patients, renal patients & those who are immunocompromised (extremely high risk) - 42,000 of the 140,000

I thought group 4 was 'very high risk' and group 5 'high risk'. I think that 140,000 is group 4.

25-02-2021 04:32PM

Is there any data on severe reactions to the vaccines locally?
I heard today that 5 carehome workers in the southeast had a severe reaction
One cant feel one of her legs and is still in hospital
Because it was a care home,I'm presuming it was the pfizer one and I'm also presuming someone mixed it wrong as they all reacted in the same centre and were from the same home?

It's not putting me off but we really are at the mercy of how good or bad our vaccinators are

ACitizenErased · 25-02-2021 04:35PM

Sconsey wrote: »

I thought group 4 was 'very high risk' and group 5 'high risk'. I think that 140,000 is group 4.

yes you are correct

Sconsey · 25-02-2021 04:37PM

ACitizenErased wrote: »

yes you are correct

LOL now I think I am wrong

It seems like they have twaked the numbers...5 very high risk, 6 high risk.

I take it back, those were just section numbers in the document!

https://www.gov.ie/en/publication/39038-provisional-vaccine-allocation-groups/

lucernarian · 25-02-2021 04:38PM

Deeper Blue wrote: »

I thought there were articles yesterday saying it was very effective?

The guy that tweeted that is a covid denying clown so I'm assuming whatever he's pointing out is fairly selective.

Yeah I was wondering why that clown was being posted here, also didn't commentate on the other high risk cohort but aren't over the age of 70 also.

Le Bruise · 25-02-2021 04:49PM

AuntySnow wrote: »

Is there any data on severe reactions to the vaccines locally?
I heard today that 5 carehome workers in the southeast had a severe reaction
One cant feel one of her legs and is still in hospital
Because it was a care home,I'm presuming it was the pfizer one and I'm also presuming someone mixed it wrong as they all reacted in the same centre and were from the same home?

It's not putting me off but we really are at the mercy of how good or bad our vaccinators are

Have only heard anecdotal evidence of headaches, fever, sore arms....all very common stuff that went away fairly quickly. Someone I work with tried to tell me the vaccine killed a friend of her grannies....but she's notoriously anti-vax, so didn't believe a word of it.

O'Neill suggested this morning that there has only been a handful of allergic reactions worldwide with over 50 million vaccinated, so they really are very safe by all accounts. Another poster might have more concrete facts on it.

KrustyUCC · 25-02-2021 04:57PM

is_that_so wrote: »

When you say GPs, how many is that - 2 or 50?

I know of at least 3 in Cork and 2 in Limerick

I don't know how widespread the issue is

"In relation to vaccine deliveries to GPs, Paul Reid said there have been some issues, particularly in the last 48 hours.

He said there has been issues this week relating to delivery, particularly for some rural GPs, describing the process as "complex".

He said there is "a lot of discussion going on" between the HSE and GP representatives to work through some of the issues."

As I said I really hope these issues get smoothed out as if we're having issues trying to sort 100,000 vaccines a week those issues could be multiplied when we're trying to get 250,000 or 300,000 a week done

Gael23 · 25-02-2021 04:57PM

Reid’s positivity swiftly counteracted by NPHET https://www.breakingnews.ie/ireland/some-time-before-normal-life-resumes-situation-remains-fragile-warns-nphet-1087393.html?fbclid=IwAR2vK3bObdHTZLQ3iEwOgy_82JTkoyFeb3vOYZEv7TInbAqWDygz8hVsXvo

Le Bruise · 25-02-2021 05:02PM

Gael23 wrote: »

Reid’s positivity swiftly counteracted by NPHET https://www.breakingnews.ie/ireland/some-time-before-normal-life-resumes-situation-remains-fragile-warns-nphet-1087393.html?fbclid=IwAR2vK3bObdHTZLQ3iEwOgy_82JTkoyFeb3vOYZEv7TInbAqWDygz8hVsXvo

The deputy CMO added that even when sufficient numbers had received the jab, "it is not possible to know at this stage what level of protection vaccination will give".

I would have thought it was fairly evident that the protection was good at this stage?

hmmm · 25-02-2021 05:06PM

Le Bruise wrote: »

The deputy CMO added that even when sufficient numbers had received the jab, "it is not possible to know at this stage what level of protection vaccination will give".

I would have thought it was fairly evident that the protection was good at this stage?

We're being a bit unfair?

I'm sure he reads the same media reports, but he can't be announcing on national TV that things are looking good until the scientists have had a chance to study the data.

Stark · 25-02-2021 05:07PM

My reading of that is at this point they're thinking "how can we get more health service funding coming into the winter?".

Turtwig · 25-02-2021 05:07PM

hmmm wrote: »

We're being a bit unfair? I'm sure he reads the same media reports, but he can't be announcing on national TV that things are looking good until the scientists have had a chance to study the data.

Letter is two weeks old too. The latest studies wouldn't have been available for reading at the time. Also, his point in his letter was related to the hospitalisation being predominantly under 65s and these would not be vaccinated for some time. So while the mortality profile should improve, hospitalisations may take considerably longer before vaccines have an impact.

Le Bruise · 25-02-2021 05:13PM

I'm possibly being harsh. I just read it as, even when everyone's been vaccinated, we don't know if they'll work (not unlike our zero covid friends).

Might have got the wrong end of the stick...t'wouldn't be the first time!:)

hmmm · 25-02-2021 05:28PM

https://www.esquire.com/news-politics/a35614976/covid-19-vaccines-good-news-variants/

This article will cheer you up if you're feeling down. Realistic but optimistic.

"A new variant still undiscovered may **** everything up. But the evidence right now simply does not point in that direction. It points to things getting better, and soon, and more people should be aware of this. "

funnydoggy · 25-02-2021 05:37PM

hmmm wrote: »

https://www.esquire.com/news-politics/a35614976/covid-19-vaccines-good-news-variants/

This article will cheer you up if you're feeling down. Realistic but optimistic.

"A new variant still undiscovered may **** everything up. But the evidence right now simply does not point in that direction. It points to things getting better, and soon, and more people should be aware of this. "

Tom, Samuel, Anthony and Gerry are crying:pac:

Van.Bosch · 25-02-2021 05:43PM

ACitizenErased wrote: »

HSE estimates of the new group 4
Total - 140,000
Cancer patients, renal patients & those who are immunocompromised (extremely high risk) - 42,000 of the 140,000

Do we have any info on how many in group 2? I think group 1 was 100,000 inc staff, so that’s almost done re dose 1. Curious to see how much more is left in group 2.

Any idea when group 4 starts?

josip · 25-02-2021 05:43PM

brickster69 wrote: »

FDA data for J&J

https://twitter.com/AlexBerenson/status/1364911005818621954

That guy is an anti-vax idiot. In another tweet

"I would say if you are forced or quasi-forced to get one and in decent health, the JNJ shot is the way to go.
Also, the media will surely repeat to infinity that there were seven #Covid deaths in the placebo arm and none in the vaccine arm...."

Sanjuro · 25-02-2021 05:51PM

hmmm wrote: »

https://www.esquire.com/news-politics/a35614976/covid-19-vaccines-good-news-variants/

This article will cheer you up if you're feeling down. Realistic but optimistic.

"A new variant still undiscovered may **** everything up. But the evidence right now simply does not point in that direction. It points to things getting better, and soon, and more people should be aware of this. "

It's funny... or maybe not funny... a bit depressing. That when I see a bunch of good news, I sometimes find myself looking for bad news. I guess that's down to a bit of conditioning over the last 12 months. But it's good to say that I'm increasingly finding it difficult to find the bad news!

COVID-19: Vaccine and testing procedures Megathread Part 3 - Read OP

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