COVID-19: Vaccine and testing procedures Megathread Part 3 - Read OP

lucernarian

Stheno wrote: »

Sever infection may not need hospitalisation?

Given that some of the criteria for severe infection necessarily require being in a hospital. I guess "death" and "systemic organ failure" doesn't need to involve a hospital but out of 20k+ people in a study, the difference between 100% and 85% could do with further clarification.

D.Q

KrustyUCC wrote: »

Funny Bouchar-Hayes, Claire Byrne and George Lee all mentioned the California Variant yesterday

If the rats on the titanic figured they could spread bull**** about variants to try save themselves they probably would too.

Same with the rats mentioned above. All the above hacks have chosen one last shot at relevance over the integrity their profession is meant to be all about.

lucernarian

D.Q wrote: »

If the rats on the titanic figured they could spread bull**** about variants to try save themselves they probably would too.

Same with the rats mentioned above. All the above hacks have chosen one last shot at relevance over the integrity their profession is meant to be all about.

They were never microbiologists to begin with, this isn't "incompetence" RTÉ are dealing with. The evidence suggests they are wrong, but if so they are in the easy position of "I'm at a party in July and everyone is nuts" while the country eases off restrictions for the last time. Not many will bring up past mistakes.

Vietnam received its first vaccines yesterday. 120k Astra Zenica. A small minority of the world's population has secured the majority of vaccines, so I think some context is important when the sky is falling.

Del Griffith

Anyone know if the Irish governments flimsy attempt at a vaccine rollout forecast (June, September, end of the year) takes into account the possibility of the J&J vaccine?
It looks very likely to be approved now, days in the USA and apparently about 2 weeks for the EU.
Could this speed things up for Ireland?

irishgeo

Del Griffith wrote: »

Anyone know if the Irish governments flimsy attempt at a vaccine rollout forecast (June, September, end of the year) takes into account the possibility of the J&J vaccine?
It looks very likely to be approved now, days in the USA and apparently about 2 weeks for the EU.
Could this speed things up for Ireland?

it's already included.

larchielads

hynesie08 wrote: »

Can we swap them? 10 AZ for a pfizer?

FYP

stephenjmcd

lbj666 wrote: »

https://twitter.com/sailorrooscout/status/1364375627953020937?s=20

Will we just turn this thread to a feed of whoever this is.

Someone would want to tell RTE. Despite multiple sources completely discrediting the report yesterday on this variant, George Lee was still discussing it as an issue yesterday evening.

lucernarian

lucernarian wrote: »

Given that some of the criteria for severe infection necessarily require being in a hospital. I guess "death" and "systemic organ failure" doesn't need to involve a hospital but out of 20k+ people in a study, the difference between 100% and 85% could do with further clarification.

100% 28 days post vaccination. The "15%" contracted the virus within the initial 28 days

harr

So after multiple good news story’s yesterday about vaccines and how successful they can be even against variants.. a lot of the Irish media still solely focused on a non story about a variation coming from the US ..
Simply because it was the only negative narrative they found yesterday.
RTÉ journalists in particular yesterday sounded even disappointed about the good news on the vaccine front.
I think a lot of them are realising now that once covid starts to drop out of the headlines they won’t be in a job and are pushing as much doom on us as they can.

is_that_so

Del Griffith wrote: »

Anyone know if the Irish governments flimsy attempt at a vaccine rollout forecast (June, September, end of the year) takes into account the possibility of the J&J vaccine?
It looks very likely to be approved now, days in the USA and apparently about 2 weeks for the EU.
Could this speed things up for Ireland?

It's not a government prediction, it's HSE/vaccination task force numbers.

Akabusi

harr wrote: »

So after multiple good news story’s yesterday about vaccines and how successful they can be even against variants.. a lot of the Irish media still solely focused on a non story about a variation coming from the US ..
Simply because it was the only negative narrative they found yesterday.
RTÉ journalists in particular yesterday sounded even disappointed about the good news on the vaccine front.
I think a lot of them are realising now that once covid starts to drop out of the headlines they won’t be in a job and are pushing as much doom on us as they can.

I agree with you on the overly negative reporting that is going on, but you are wrong to think that these journalists will not have their jobs once this is over. They had them long before the Covid and will keep them after it is gone.

Stark

Del Griffith wrote: »

Anyone know if the Irish governments flimsy attempt at a vaccine rollout forecast (June, September, end of the year) takes into account the possibility of the J&J vaccine?
It looks very likely to be approved now, days in the USA and apparently about 2 weeks for the EU.
Could this speed things up for Ireland?

Only people left to be done in September will be a few people who got their first Astrazenaca dose in June and those people will have been low risk to begin with. By end of June, Ireland should be mostly in a good place to lift lockdown restrictions imo.

dominatinMC

harr wrote: »

So after multiple good news story’s yesterday about vaccines and how successful they can be even against variants.. a lot of the Irish media still solely focused on a non story about a variation coming from the US ..
Simply because it was the only negative narrative they found yesterday.
RTÉ journalists in particular yesterday sounded even disappointed about the good news on the vaccine front.
I think a lot of them are realising now that once covid starts to drop out of the headlines they won’t be in a job and are pushing as much doom on us as they can.

I sat aghast listening to George Lee on the 6.1 yesterday evening (don't know why I do it to myself!) reporting on yet another new variant, whilst completely failing to acknowledge the fact that the new J&J vaccine is extremely effective against all variants which it was trialled on. At this stage I'm beginning to wonder if it is ignorance, rather than deliberate negligence.

josip

Akabusi wrote: »

I agree with you on the overly negative reporting that is going on, but you are wrong to think that these journalists will not have their jobs once this is over. They had them long before the Covid and will keep them after it is gone.

Correct.
But they'll no longer be relevant and in the public eye.
Which is catnip for journalists.

Le Bruise

Not sure if discussed previously, but Luke O'Neill was on Newstalk earlier, bigging up the vaccine from French company Valneva.

Apparently it'll work well against any variant due to the technology used, so no seasonal tweaking needed. In phase II trials now, hoping for Q3 approval.

Azatadine

Le Bruise wrote: »

Not sure if discussed previously, but Luke O'Neill was on Newstalk earlier, bigging up the vaccine from French company Valneva.

Apparently it'll work well against any variant due to the technology used, so no seasonal tweaking needed. In phase II trials now, hoping for Q3 approval.

Wait until Ryan, Staines, McConkey and Killeen get wind of it. Doubtless, they will have some scientific rationale to dispute its purported efficacy.......not.......these scientists don't believe the science......not worthy of being called scientists.

marno21

Le Bruise wrote: »

Not sure if discussed previously, but Luke O'Neill was on Newstalk earlier, bigging up the vaccine from French company Valneva.

Apparently it'll work well against any variant due to the technology used, so no seasonal tweaking needed. In phase II trials now, hoping for Q3 approval.

Itll be the first inactivated virus vaccine approved in much of the western world (the Chinese vaccines are of this type)

Given that it includes the whole virus it would confer immunity to more than just the spike protein, so wouldn’t be affected by the spike protein mutations.

Le Bruise

marno21 wrote: »

Itll be the first inactivated virus vaccine approved in much of the western world (the Chinese vaccines are of this type)

Given that it includes the whole virus it would confer immunity to more than just the spike protein, so wouldn’t be affected by the spike protein mutations.

Thanks for that, was trying to remember exactly how he said it was achieved!

ceegee

Monday update

Melanchthon

Le Bruise wrote: »

Not sure if discussed previously, but Luke O'Neill was on Newstalk earlier, bigging up the vaccine from French company Valneva.

Apparently it'll work well against any variant due to the technology used, so no seasonal tweaking needed. In phase II trials now, hoping for Q3 approval.

Its been mentioned before. They have started bulk manufacturing in the UK and it would seem likely that the UK has priority on that production.

The U.K. has signed a deal to secure 40 million extra doses of Valneva's coronavirus vaccine candidate, in addition to the 60 million it had already agreed to buy, the government and the French biotech announced Monday.

The new deal follows a multi-million-pound joint investment in Valneva's facility in Livingston, West Lothian, by the U.K. in 2020 as part of an in-principle agreement to secure early access.

The EU was in preliminary talks in January so presumably they have concluded but not seeing much else but since I do not read French I might be missing it, and as a French company they might already have production capacity within the EU.

irishlad.

ceegee wrote: »

Monday update

Not the best start to our 100k target this week. Hopefully we can catch up

marno21

irishlad. wrote: »

Not the best start to our 100k target this week. Hopefully we can catch up

The document doesn’t tell us when the doses are being delivered or distributed so it may be best to withhold judgment on the weekly target until the end of the week

irishlad.

marno21 wrote: »

The document doesn’t tell us when the doses are being delivered or distributed so it may be best to withhold judgment on the weekly target until the end of the week

We won't be too far away, I don't doubt the rollout

Hmmzis

marno21 wrote: »

Itll be the first inactivated virus vaccine approved in much of the western world (the Chinese vaccines are of this type)

Given that it includes the whole virus it would confer immunity to more than just the spike protein, so wouldn’t be affected by the spike protein mutations.

With one caveat that only the S protein so far has been found to have any neutralizing epitopes. The binding of antibodies is minimally affected by any mutations so far. Binding ABs can be useful if the virus cannot productively replicate in human macrophages, so far it looks like we're in the clear with this one.

seamus

marno21 wrote: »

The document doesn’t tell us when the doses are being delivered or distributed so it may be best to withhold judgment on the weekly target until the end of the week

If you compare the reports day-by-day, you can see figures constantly being backfilled. So whatever is reported today as being done on Monday isn't the final figure, only what has been reported as of today.

I expect as numbers ramp up, priority will be given by doctors to the actual vaccinations rather than reporting the numbers, so we'll always be 5-7 days behind.

marno21

seamus wrote: »

If you compare the reports day-by-day, you can see figures constantly being backfilled. So whatever is reported today as being done on Monday isn't the final figure, only what has been reported as of today.

I expect as numbers ramp up, priority will be given by doctors to the actual vaccinations rather than reporting the numbers, so we'll always be 5-7 days behind.

Indeed. I was thinking that the move to daily reporting would just lead to criticism of the rollout due to incomplete data/variance of day to day totals etc. It’s the weekly figures that tell the real story

And of course, shots into arms is a far more important use of resources than accurate reporting

tfeldi

marno21 wrote: »

Indeed. I was thinking that the move to daily reporting would just lead to criticism of the rollout due to incomplete data/variance of day to day totals etc. It’s the weekly figures that tell the real story

And of course, shots into arms is a far more important use of resources than accurate reporting

Solid and on time HSE internal reporting is crucial to plan resources and identify issues. And when you have a solid internal reporting process you can then easily share summary Numbers externally. Keep in mind that it is not medical personnel preparing the reporting.

titan18

tfeldi wrote: »

Solid and on time HSE internal reporting is crucial to plan resources and identify issues. And when you have a solid internal reporting process you can then easily share summary Numbers externally. Keep in mind that it is not medical personnel preparing the reporting.

Yup, as someone in a data/reporting role, I find it absolutely ridiculous that there's a lag of 2-3 days never mind that even with that lag, it's still not correct. Must be some ****ty system/process in place to not be able to report correctly.

funnydoggy

Tomas Ryan trying to stay relevant by bombarding media outlets saying that the government won't have mass vaccinations by April. He may be right or wrong, but nobody said this would be the case. He wants a NPHET position for the next pandemic, IMO.

https://www.newstalk.com/news/ireland-will-be-nowhere-near-widespread-vaccination-by-april-tomas-ryan-1155791