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Covid 19 Part XX-26,644 in ROI (1,772 deaths) 6,064 in NI (556 deaths) (08/08)Read OP

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Comments

  • Registered Users, Registered Users 2 Posts: 20,111 ✭✭✭✭cnocbui


    ShineOn7 wrote: »
    That's a mental stat. They're doctors, so a poor income doesn't come into it

    African originals are more susceptible to hypertension, which is also linked to the ACE2 receptor: listen from 13:50

    https://www.thirteen.org/openmind/science/the-pandemics-prophet/6416/

    Given underlying hypertension is probably the most significant risk factor for SARS-2 related death...


  • Registered Users, Registered Users 2 Posts: 11,675 ✭✭✭✭ACitizenErased




  • Registered Users, Registered Users 2 Posts: 20,111 ✭✭✭✭cnocbui



    Ha, ha, ha. Go tell it to those who have been reinfected.

    Winning the Euromillions is highly unlikely, but guess what?


  • Registered Users, Registered Users 2 Posts: 11,675 ✭✭✭✭ACitizenErased


    HSE Daily Operations Update

    14 in hospitals, no change.
    1 admission/confirmed case in Drogheda today and 2 overnight in Vincents and Tallaght.
    6 in ICU, down by 1.
    1 death in the past 24 hours.
    4 being ventilated, down by 1.


  • Registered Users Posts: 596 ✭✭✭majcos


    cnocbui wrote: »
    Ha, ha, ha. Go tell it to those who have been reinfected.

    Winning the Euromillions is highly unlikely, but guess what?
    Testing positive again does not necessarily mean you are infected or infectious to others again. The viral PCR swabs can detect ‘remnant’ RNA particles for many many weeks in some patients even though they may no longer be infectious.

    Publication in Nature showed virus could not be grown from the nose and throat after day 8 even when the viral nucleic acid could still be found, i.e. swabs were still positive.


    https://www.nature.com/articles/s41586-020-2196-x?fbclid=IwAR0dxTczGh6zOK3e0mvBEtNPOIdO5rK9na6RNpd2LPS5cCorbiViL8a9XlU


  • Registered Users, Registered Users 2 Posts: 10,462 ✭✭✭✭WoollyRedHat


    In terms of how infections and conditions can affect different people, different ethnicities and people with co morbidities, the role of precision medicine with focus on data analytics, computational modelling and utilisation of AI is key for developing better treatments and better patient outcomes.

    This is becoming increasingly important and is changing the way we treat people from cancer to diabetes to viruses , even on a singular level, which can have an impact on quality of life and outcomes. The approach of a one size fits all approach has it's limitations.Some great research programs tackling this both here and internationally at the moment.


  • Registered Users Posts: 596 ✭✭✭majcos


    cnocbui wrote: »
    Ha, ha, ha. Go tell it to those who have been reinfected.

    Winning the Euromillions is highly unlikely, but guess what?
    How much of your 49.5 million are you willing to donate to research?


  • Registered Users Posts: 596 ✭✭✭majcos


    In terms of how infections can effect different people, different ethnicities and people with co morbidities, the role of precision medicine with focus on data analytics, computational modelling and utilisation of AI is key for developing better treatments and better patients is becoming increasingly important and is changing the way we treat people from cancer to diabetes to viruses which can have an impact on quality of life and morbidity. The approach of a one size fits all approach has it's limitations and this field if medicine is a rapidly expanding one.
    Yes. Medicine should become eventually more tailored to the individual patient so better treatments with less side effects.


  • Registered Users, Registered Users 2 Posts: 10,462 ✭✭✭✭WoollyRedHat


    majcos wrote: »
    Yes. Medicine should become eventually more tailored to the individual patient so better treatments with less side effects.

    Yes definitely, basically a systems biology approach, no one person is the same.


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  • Registered Users, Registered Users 2 Posts: 5,328 ✭✭✭Ardent


    majcos wrote: »
    There is also a higher risk of hypertension in black population. 1.8 times as likely to be hypertensive compared to Caucasians as per this paper

    https://www.ahajournals.org/doi/full/10.1161/hypertensionaha.110.163196

    This has been related to ACE gene

    https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0204127

    And ACE gene which has been linked to C-19.

    https://www.sciencedirect.com/science/article/pii/S1684118220301092



    There was concern for a time that blood pressure medication might be responsible for severe covid symptoms. However, multiple medical and scientific reports are showing that blood pressure medication is actually beneficial against covid. The current thought behind the reason for this is that the increased ACE2 receptors lead the disease away from the receptors in the lungs, effectively sending it up a cul-de-sac.

    Here's a recent NYT article on it:
    http://archive.ph/foba2

    Regarding severe illness in BAME folks, the widely accepted view behind the cause of this is vitamin D deficiency.


  • Registered Users, Registered Users 2 Posts: 87,594 ✭✭✭✭JP Liz V1


    https://www.independent.ie/irish-news/shed-say-shes-lived-so-long-from-going-to-mass-every-day-dublin-woman-celebrates-104th-birthday-after-overcoming-covid-19-39389597.html

    Dubliner Josephine Silo celebrated her 104th birthday “in great form” today after overcoming Covid-19 earlier in the month.

    Ms Silo’s family threw her a garden party to celebrate and despite her advanced years, her niece Anna Colfer said she was the life of the party.

    “She’s in great form, she’s the centre of attention and loving it all,” she said.


  • Registered Users Posts: 596 ✭✭✭majcos


    Ardent wrote: »
    There was concern for a time that blood pressure medication might be responsible for severe covid symptoms. However, multiple medical and scientific reports are showing that blood pressure medication is actually beneficial against covid. The current thought behind the reason for this is that the increased ACE2 receptors lead the disease away from the receptors in the lungs, effectively sending it up a cul-de-sac.
    http://archive.ph/foba2

    Regarding severe illness in BAME folks, the widely accepted view behind the cause of this is vitamin D deficiency.
    As far as I understand now, not the blood pressure medications but having high blood pressure itself in the first place that is believed to increase risk of poorer outcome.

    Don’t want anyone to stop taking their blood pressure tablets!


  • Closed Accounts Posts: 4,550 ✭✭✭ShineOn7


    From Reddit UAE
    'The UAE's r-rate - which indicates the reproduction rate of the virus - has been calculated at 0.74. A rate below one is considered positive as it means that, if maintained over time, the virus will eventually be eliminated.'

    Is the bit in bold true?

    I thought we were long past true eradication in the vast majority of major countries (apart from maybe New Zealand and Australia)


  • Registered Users, Registered Users 2 Posts: 2,139 ✭✭✭What Username Guidelines


    HSE Daily Operations Update

    14 in hospitals, no change.
    1 admission/confirmed case in Drogheda today and 2 overnight in Vincents and Tallaght.
    6 in ICU, down by 1.
    1 death in the past 24 hours.
    4 being ventilated, down by 1.

    Lots of changes in those 14 patients when comparing with yesterday.

    Mater -3
    Tallaght -1 +1
    Drogheda +1
    Kerry +2
    Waterford -1
    Naas +1 -1
    Vincents +1 -1 +1


  • Registered Users, Registered Users 2 Posts: 8,382 ✭✭✭petes


    pjohnson wrote: »
    When he dries his eyes a bit that'll be you *ignored* next.

    It's a trait some of the more narcissistic posters have. I'll post this and I'm right...I'm always right.They won't post for a while after being proved wrong or called out and then think that posters won't remember so they'll start posting in the thread again :)


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  • Registered Users, Registered Users 2 Posts: 2,021 ✭✭✭Miike


    ShineOn7 wrote: »
    From Reddit UAE



    Is the bit in bold true?

    I thought we were long past true eradication in the vast majority of major countries (apart from maybe New Zealand and Australia)

    If the R0 drops below 1.0 the virus will EVENTUALLY fizzle out in the population (if the R0 is kept below 1). The R0 is just the basic reproduction number where 1 = 1 person infected with COVID19 is likely to infect one other person over the course of the persons infectious period.

    This is often confused with the Re - The effective reproduction number. Which is a whole new kettle of fish!


  • Closed Accounts Posts: 4,550 ✭✭✭ShineOn7


    Miike wrote: »
    If the R0 drops below 1.0 the virus will EVENTUALLY fizzle out in the population (if the R0 is kept below 1). The R0 is just the basic reproduction number where 1 = 1 person infected with COVID19 is likely to infect one other person over the course of the persons infectious period.


    Oh I know what the R0 means

    I just didn't think eradication was possible in the majority of countries with Covid


  • Registered Users, Registered Users 2 Posts: 2,021 ✭✭✭Miike


    ShineOn7 wrote: »
    Oh I know what the R0 means

    I just didn't think eradication was possible in the majority of countries with Covid

    The only way to really make the R0 drop below 1 and stay there, for the potential of 'eradication' would be to lock the country up and close the borders. It's not realistic to say that the virus will die out completely. The R0 is variable and has limitations i.e. even with an R0 of below one you can still have outbreaks.


  • Moderators, Recreation & Hobbies Moderators Posts: 11,655 Mod ✭✭✭✭igCorcaigh


    Still not known if warmer weather slows Covid-19 spread – study

    https://www.breakingnews.ie/world/still-not-known-if-warmer-weather-slows-covid-19-spread-study-1012046.html?utm_source=dlvr.it&utm_medium=twitter

    I guess there are too many variables involved, but I had hoped we would have at least learned something about this issue by now.


  • Moderators, Recreation & Hobbies Moderators Posts: 11,655 Mod ✭✭✭✭igCorcaigh


    Miike wrote: »
    If the R0 drops below 1.0 the virus will EVENTUALLY fizzle out in the population (if the R0 is kept below 1). The R0 is just the basic reproduction number where 1 = 1 person infected with COVID19 is likely to infect one other person over the course of the persons infectious period.

    This is often confused with the Re - The effective reproduction number. Which is a whole new kettle of fish!

    Yes, theoretically, but the R0 is an average and can vary according to local conditions etc.


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  • Closed Accounts Posts: 1,089 ✭✭✭Non solum non ambulabit


    cnocbui wrote: »
    Ha, ha, ha. Go tell it to those who have been reinfected.

    Winning the Euromillions is highly unlikely, but guess what?

    If reinfection was as rare as Euromillions win then it would be so rare as to be irrelevant

    Odds on winning Euromillions 140 million to 1

    There are 15 million confirmed cases worldwide. So Confirmed cases would need to increase 10 fold before statistically we would get a reinfection.


  • Closed Accounts Posts: 1,089 ✭✭✭Non solum non ambulabit


    ShineOn7 wrote: »
    From Reddit UAE

    A rate below one is considered positive as it means that, if maintained over time, the virus will eventually be eliminated.'

    Is the bit in bold true?

    Is that a serious question? Of course it's true. An R rate below 1 can only lead to eradication over time.


  • Registered Users, Registered Users 2 Posts: 8,365 ✭✭✭ceadaoin.


    majcos wrote: »
    As far as I understand now, not the blood pressure medications but having high blood pressure itself in the first place that is believed to increase risk of poorer outcome.

    Don’t want anyone to stop taking their blood pressure tablets!

    In my area, out of 577 total deaths, 257 had hypertension as an underlying condition. Seems to be a big risk but it may be over represented because its a fairly common condition?


  • Registered Users Posts: 5,513 ✭✭✭bb1234567


    ceadaoin. wrote: »
    In my area, out of 577 total deaths, 257 had hypertension as an underlying condition. Seems to be a big risk but it may be over represented because its a fairly common condition?

    Yeh, fairly common is an understatement! Especially given the age of most people who have died.

    75% of people over 70 have hypertension
    https://www.ncbi.nlm.nih.gov/books/NBK9636/


  • Registered Users Posts: 1,800 ✭✭✭Always_Running


    Miike wrote: »
    If the R0 drops below 1.0 the virus will EVENTUALLY fizzle out in the population (if the R0 is kept below 1). The R0 is just the basic reproduction number where 1 = 1 person infected with COVID19 is likely to infect one other person over the course of the persons infectious period.

    This is often confused with the Re - The effective reproduction number. Which is a whole new kettle of fish!

    Didn't see it reported lately, does anyone want to guess what the RO number is in Ireland right now?


  • Moderators, Education Moderators, Technology & Internet Moderators Posts: 35,100 Mod ✭✭✭✭AlmightyCushion


    Didn't see it reported lately, does anyone want to guess what the RO number is in Ireland right now?

    I think it gets reported on a thursday. Given our 7 day rolling average has stayed relatively steady the past week, I'm gonna guess somewhere around 1.


  • Registered Users, Registered Users 2 Posts: 8,365 ✭✭✭ceadaoin.


    bb1234567 wrote: »
    Yeh, fairly common is an understatement! Especially given the age of most people who have died.

    75% of people over 70 have hypertension
    https://www.ncbi.nlm.nih.gov/books/NBK9636/

    Wow, I didn't realise that many people have it!


  • Registered Users, Registered Users 2 Posts: 20,111 ✭✭✭✭cnocbui


    majcos wrote: »
    How much of your 49.5 million are you willing to donate to research?

    My neighbour Dolores won €113 m, I'll let her go first.


  • Moderators, Recreation & Hobbies Moderators Posts: 11,655 Mod ✭✭✭✭igCorcaigh


    Is that a serious question? Of course it's true. An R rate below 1 can only lead to eradication over time.

    In a mathematical sense, yes. Exponential decay.

    But R0 is an average in an equation. There may be localities where the outbreak rises.


  • Registered Users Posts: 5,513 ✭✭✭bb1234567


    https://www.google.ie/amp/s/amp.cnn.com/cnn/2020/07/21/us/felician-sisters-covid-deaths-trnd/index.html

    Michigan convent loses 13 sisters to Covid ,really terrible I'd imagine nuns largely keep within their own social circle and is a devastating loss to the surviving 37 members . RIP.


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  • Registered Users, Registered Users 2 Posts: 87,594 ✭✭✭✭JP Liz V1


    bb1234567 wrote: »
    https://www.google.ie/amp/s/www.clickondetroit.com/news/local/2020/07/22/13-nuns-at-livonia-convent-die-from-covid-19/%3foutputType=amp

    Michigan convent loses 13 sisters to Covid, really terrible I'd imagine nuns largely keep within their own social circle and is a devastating loss to the surviving members . RIP.

    RIP :(


  • Registered Users, Registered Users 2 Posts: 20,111 ✭✭✭✭cnocbui


    ceadaoin. wrote: »
    Wow, I didn't realise that many people have it!

    It might have something to do with the US medical authorities, regularly revising downward the blood pressure ranges assigned to the labels low, normal, high, etc. Of course the fact this leads to massive increases in the sales of statins and other medications is just a very profitable coincidence.


  • Registered Users, Registered Users 2 Posts: 2,354 ✭✭✭nocoverart


    Quickly read over some of the older threads from the links here. Very interesting to look back on it. I think we’d be very pleased with where we are now from judging the mood back then. Easy to drowned in the here and now, but the here and now is way more optimistic than the ghosts of the scaremongering boardies past
    predicted.


  • Registered Users, Registered Users 2 Posts: 87,594 ✭✭✭✭JP Liz V1


    HSE Daily Operations Update

    14 in hospitals, no change.
    1 admission/confirmed case in Drogheda today and 2 overnight in Vincents and Tallaght.
    6 in ICU, down by 1.
    1 death in the past 24 hours.
    4 being ventilated, down by 1.

    Is the death the doctor from the Mater, in hospital fighting Covid for 3 months, brave selfless hero, RIP


  • Registered Users, Registered Users 2 Posts: 38,966 ✭✭✭✭eagle eye


    Are we heading back to stage 2? I hope not but hard to know what happens if the R0 increases again.
    Have we been given the reasons why it's increasing? Are incomers a big part of it?


  • Registered Users, Registered Users 2 Posts: 87,594 ✭✭✭✭JP Liz V1


    eagle eye wrote: »
    Are we heading back to stage 2? I hope not but hard to know what happens if the R0 increases again.
    Have we been given the reasons why it's increasing? Are incomers a big part of it?

    I think someone on one of these threads already mentioned clusters increasing it


  • Posts: 0 [Deleted User]


    ceadaoin. wrote: »
    Wow, I didn't realise that many people have it!

    As we get older arteries stiffen and rates of hypertension consequently rise. There is nothing abnormal in this and is why as we get older risk of heart disease, stroke etc increase. To some however this seems to mean that these people were about to die anyway so the fact they died of COVID is inconsequential.


  • Closed Accounts Posts: 2,329 ✭✭✭owlbethere


    eagle eye wrote: »
    Are we heading back to stage 2? I hope not but hard to know what happens if the R0 increases again.
    Have we been given the reasons why it's increasing? Are incomers a big part of it?

    I think it was reported before about the RO. During lockdown people were meeting less people and the RO declined for that reason.

    Now restrictions are lifting, the RO is increasing.

    My understanding of the RO as well is that it comes down to the number of people anyone meets in any day or week. So some confirmed people might belong to a cluster that has a small number of cases. Other people might belong to a cluster that has a larger number of people. I think they might give the average RO over all the cases.

    We were urged a few weeks ago while the restrictions were lifting to keep the number of our close daily contacts down low. Many people are probably following this advice going forward. It makes sense to continue with reduced social movements for now and hopefully a vaccine will be through later in the year. Other people want to rush back and out to the way life was and socialise as before in crowds. Its these people that will skew the RO into a higher number because of the average over cases.


  • Closed Accounts Posts: 1,543 ✭✭✭Dante7


    eagle eye wrote: »
    Are we heading back to stage 2? I hope not but hard to know what happens if the R0 increases again.
    Have we been given the reasons why it's increasing? Are incomers a big part of it?

    No.
    It's not.
    No.


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  • Registered Users Posts: 3,428 ✭✭✭ZX7R


    I was out and about yesterday tying up a few things before my family and I depart these shores.
    I was quite happily surprised by the numbers of people wearing masks there has definitely been a huge uptake in the wearing of them.
    It was great to see.


  • Posts: 0 [Deleted User]


    ^^^^ I’ve seen a good uptake too.

    I was concerned on Monday evening though when I went into my local shop. Around 7 girls had just finished their gaa training and came in. None of them had a mask on and they were back and forth to the counter (as kids do). I had hoped their parents would have provided them with face coverings and told them to wear them but there were no signs of having them at all.

    Hopefully it was first day forgetfulness and will be different next Monday.


  • Registered Users Posts: 3,428 ✭✭✭ZX7R


    ^^^^ I’ve seen a good uptake too.

    I was concerned on Monday evening though when I went into my local shop. Around 7 girls had just finished their gaa training and came in. None of them had a mask on and they were back and forth to the counter (as kids do). I had hoped their parents would have provided them with face coverings and told them to wear them but there were no signs of having them at all.

    Hopefully it was first day forgetfulness and will be different next Monday.

    My small village local shop refuse to serve if you don't have a mask since Monday


  • Closed Accounts Posts: 475 ✭✭Onesea


    ZX7R wrote: »
    My small village local shop refuse to serve if you don't have a mask since Monday

    The kids can train together in gaa but as soon as they enter a shop they have to wear a mask.
    How many months did we not wear masks in shops and the virus didn't notice?
    Nice long q outside yet free for all inside.


  • Closed Accounts Posts: 12,653 ✭✭✭✭Plumbthedepths


    ^^^^ I’ve seen a good uptake too.

    I was concerned on Monday evening though when I went into my local shop. Around 7 girls had just finished their gaa training and came in. None of them had a mask on and they were back and forth to the counter (as kids do). I had hoped their parents would have provided them with face coverings and told them to wear them but there were no signs of having them at all.

    Hopefully it was first day forgetfulness and will be different next Monday.

    Face coverings are not recommended for young children.


  • Closed Accounts Posts: 2,329 ✭✭✭owlbethere


    ZX7R wrote: »
    My small village local shop refuse to serve if you don't have a mask since Monday

    My small village shop is the opposite. I've been once but asking others and the mask wearing is hit and miss. Definitely not be enforced where I am.


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  • Posts: 0 [Deleted User]


    Onesea wrote: »
    The kids can train together in gaa but as soon as they enter a shop they have to wear a mask.
    How many months did we not wear masks in shops and the virus didn't notice?
    Nice long q outside yet free for all inside.

    Inside / Outside - it is different you know


  • Closed Accounts Posts: 474 ✭✭ChelseaRentBoy


    ^^^^ I’ve seen a good uptake too.

    I was concerned on Monday evening though when I went into my local shop. Around 7 girls had just finished their gaa training and came in. None of them had a mask on and they were back and forth to the counter (as kids do). I had hoped their parents would have provided them with face coverings and told them to wear them but there were no signs of having them at all.

    Hopefully it was first day forgetfulness and will be different next Monday.

    Did you call them out on it?


  • Closed Accounts Posts: 475 ✭✭Onesea


    Inside / Outside - it is different you know

    You get what I mean, none of it makes any sense. The government acting brainless on purpose would make you wonder.


  • Registered Users, Registered Users 2 Posts: 2,145 ✭✭✭Sparko


    JP Liz V1 wrote: »
    Is the death the doctor from the Mater, in hospital fighting Covid for 3 months, brave selfish hero, RIP

    I assume when you wrote selfish you meant selfless! RIP


  • Posts: 0 [Deleted User]


    Onesea wrote: »
    The kids can train together in gaa but as soon as they enter a shop they have to wear a mask.
    How many months did we not wear masks in shops and the virus didn't notice?
    Nice long q outside yet free for all inside.

    The fact that they are training together means when they will then be in the vicinity of all other ages (the shop) they should wear a covering.

    @plumb
    These were girls of 11-12 years old.


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