COVID-19: Vaccine/antidote and testing procedures Megathread [Mod Warning - Post #1]

Sconsey · 20-09-2020 12:17PM

ExMachina1000 wrote: »

Did we ever have a coronavirus vaccine before? No

Did we try ? Yes

That's my point and its true

Is the sky blue? Yes

Do cats bark? No

That's my point and they are both true....but they are irrelevant, like your post.

20-09-2020 12:19PM

ExMachina1000 wrote: »

Do you know how many successful vaccines have been created for any coronavirus?

Il give you a hint . It's less than 1

This has been said several times before and it's not accurate. First of all we have developed coronavirus vaccines for animals. There are vaccines for cows, dogs and cats.

Secondly most coronaviruses cause only mild symptoms so it makes little practical sense to invest so much time and money into making a vaccine for something that only causes issues for a tiny minority of people. An effort was made for SARS but the virus was eradicated so it became redundant. As for MERS that only causes about 200 cases per year in the Middle East so funding one is not a priority sadly. Incidentally some of the research for SARS and MERS has been reused in the creation of the current vaccine.

Thirdly there are 7 coronaviruses know to infect humans. 6 of them have been discovered since 2002. Our knowledge of them is still relatively new.

Micky 32 · 20-09-2020 12:19PM

firemansam4 wrote: »

So unless you or the other poster can provide solid evidence that there won't be by the end of next year never mind next decade as the other poster suggests, then all use are doing is posting negative rubbish without any substance to it.

I do hope we do get a vaccine for their sake! I’d hate to see anyone go through the misery of being stuck under their beds for years to come.

smurfjed · 20-09-2020 12:32PM

How many of you would be willing to take the vaccine developed by Shinopharm and available in the UAE?

Marhay70 · 20-09-2020 12:33PM

We didn't have a vaccine for Polio until we had one.
We didn't have a vaccine for Smallpox until we had one
We didn't have a vaccine for Measles until we had one.
All of these, once devastating, diseases are now under control.
We'll have a vaccine for Covid when we have one. That could be next week, next month next year, exactly as it was with the others at one time and I'm pretty sure there were the usual bullshi**ers and naysayers around while they were being developed too.

is_that_so · 20-09-2020 12:36PM

smurfjed wrote: »

How many of you would be willing to take the vaccine developed by Shinopharm and available in the UAE?

It's still at Phase III, it's emergency use only for now.

CiarraiManc · 20-09-2020 01:38PM

firemansam4 wrote: »

Between this and the main thread your posts seem to come across as some of the most negative I've seen.
I just really hope that you actually don't believe some of this stuff you post, for the sake of your own mental health.

I'll worry about my mental health thanks, none of your business. I'm just accepting the situation for what it is rather than believing some magic vaccine is right around the corner.

CiarraiManc · 20-09-2020 01:43PM

Marhay70 wrote: »

We didn't have a vaccine for Polio until we had one.
We didn't have a vaccine for Smallpox until we had one
We didn't have a vaccine for Measles until we had one.
All of these, once devastating, diseases are now under control.
We'll have a vaccine for Covid when we have one. That could be next week, next month next year, exactly as it was with the others at one time and I'm pretty sure there were the usual bullshi**ers and naysayers around while they were being developed too.

Well alright then genius, how come there isn't a HIV vaccine, or a cancer vaccine? Those have been around much longer than covid and nothing. I'll wait for your response

20-09-2020 01:48PM

CiarraiManc wrote: »

Well alright then genius, how come there isn't a HIV vaccine, or a cancer vaccine? Those have been around much longer than covid and nothing. I'll wait for your response

Serious?

kona · 20-09-2020 01:53PM

CiarraiManc wrote: »

Well alright then genius, how come there isn't a HIV vaccine, or a cancer vaccine? Those have been around much longer than covid and nothing. I'll wait for your response

A cancer vaccine:rolleyes:

Deeper Blue · 20-09-2020 01:54PM

CiarraiManc wrote: »

Well alright then genius, how come there isn't a HIV vaccine, or a cancer vaccine? Those have been around much longer than covid and nothing. I'll wait for your response

You sarcastically refer to that poster as genius and then proceed to compare covid to cancer and HIV?

CiarraiManc · 20-09-2020 01:54PM

[Deleted User] wrote: »

Serious?

Serious. I don't see how someone can be naive enough to believe covid can be fixed quicker than those illnesses that have been around much longer and have had much more funding

firemansam4 · 20-09-2020 01:54PM

CiarraiManc wrote:

I'll worry about my mental health thanks, none of your business. I'm just accepting the situation for what it is rather than believing some magic vaccine is right around the corner.

"Magic vaccine"

That tells me all I need to know where your coming from.

How about instead of posting this negative nonsense you actually back it up with evidence?

Trying to argue that a vaccine is unlikely because there are not vaccines for other diseases out there is not evidence in any way at all.

CiarraiManc · 20-09-2020 01:55PM

kona wrote: »

A cancer vaccine:rolleyes:

What's the HPV vaccine then genius?

CiarraiManc · 20-09-2020 01:56PM

firemansam4 wrote: »

"Magic vaccine"

That tells me all I need to know where your coming from.

How about instead of posting this negative nonsense you actually back it up with evidence?

Trying to argue that a vaccine is unlikely because there are not vaccines for other diseases out there is not evidence in any way at all.

I'm not disputing the possibility of a vaccine so much as the timeframe which is impossibly optimistic

lozenges · 20-09-2020 02:00PM

CiarraiManc wrote: »

Well alright then genius, how come there isn't a HIV vaccine, or a cancer vaccine? Those have been around much longer than covid and nothing. I'll wait for your response

There is a vaccine against cervical cancer. The HPV vaccine.
Most other forms of cancer are not caused by infectious diseases, hence no vaccine.

firemansam4 · 20-09-2020 02:01PM

CiarraiManc wrote:

I'm not disputing the possibility of a vaccine so much as the timeframe which is impossibly optimistic

OK maybe we should close this thread so, all the information and results from various trials around the world must be false.
CiarraiManc knows best, it will be at least a decade before this "Magic Vaccine" becomes a reality...

yosemitesam1 · 20-09-2020 02:07PM

Hardyn wrote: »

This has been said several times before and it's not accurate. First of all we have developed coronavirus vaccines for animals. There are vaccines for cows, dogs and cats.

Secondly most coronaviruses cause only mild symptoms so it makes little practical sense to invest so much time and money into making a vaccine for something that only causes issues for a tiny minority of people. An effort was made for SARS but the virus was eradicated so it became redundant. As for MERS that only causes about 200 cases per year in the Middle East so funding one is not a priority sadly. Incidentally some of the research for SARS and MERS has been reused in the creation of the current vaccine.

Thirdly there are 7 coronaviruses know to infect humans. 6 of them have been discovered since 2002. Our knowledge of them is still relatively new.

Something that hasn't been questioned enough is what will the vaccine actually do.
The cattle vaccine is used to give a boost of antibodies in colostrum, it does nothing to actually stop coronavirus being present in a population.
We will most likely end up in a position where fit and healthy people are getting vaccinations that they don't really need, while the most at risk struggle to benefit much if at all. The at risk populations are also not going to get any worthwhile protection from the rest of the population being vaccinated as with other coronavirus vaccines, the vaccinated still possess the ability to carry/shed infective virus

20-09-2020 02:24PM

CiarraiManc wrote: »

What's the HPV vaccine then genius?

HPV vaccine protects against Human Papillomavirus. The effects of which can lead to cancer. It doesn't protect against cancer itself.

Hmmzis · 20-09-2020 03:22PM

yosemitesam1 wrote: »

Something that hasn't been questioned enough is what will the vaccine actually do.
The cattle vaccine is used to give a boost of antibodies in colostrum, it does nothing to actually stop coronavirus being present in a population.
We will most likely end up in a position where fit and healthy people are getting vaccinations that they don't really need, while the most at risk struggle to benefit much if at all. The at risk populations are also not going to get any worthwhile protection from the rest of the population being vaccinated as with other coronavirus vaccines, the vaccinated still possess the ability to carry/shed infective virus

You raise an intersting point. What do the current animal CoV vaccines actually do?

https://www.sciencedirect.com/science/article/pii/S0264410X20307994

I've read only the abstract at this point, but it's intersting to see researchers looking at this question as well. The first thing that pops out is the type employed - they're all inactivated with some adjuvants (Merck uses alum in their dog vaccines). Doesn't get any simpler than that. The biggest issues appear to be from CoVs that have fast antigen drift - they mutate away very quickly, so the vaccine makers have to keep playing catch-up all the time. The cat one needs work as well.

20-09-2020 03:30PM

CiarraiManc wrote: »

What's the HPV vaccine then genius?

A vaccine against the human papilloma virus, which can cause cancer but is not cancer. It’s also a virus type there was no vaccine against, until there was

yosemitesam1 · 20-09-2020 04:00PM

Hmmzis wrote: »

You raise an intersting point. What do the current animal CoV vaccines actually do?

https://www.sciencedirect.com/science/article/pii/S0264410X20307994

I've read only the abstract at this point, but it's intersting to see researchers looking at this question as well. The first thing that pops out is the type employed - they're all inactivated with some adjuvants (Merck uses alum in their dog vaccines). Doesn't get any simpler than that. The biggest issues appear to be from CoVs that have fast antigen drift - they mutate away very quickly, so the vaccine makers have to keep playing catch-up all the time. The cat one needs work as well.

It's important to keep in mind when reading that, animal vaccines are purely aimed at the young animal. We are looking to protect the elderly with covid vaccine.
Also the population dynamics of poultry/pigs are very different due to large indoor farms.

Thierry12 · 20-09-2020 04:51PM

Oxford one in big trouble

Another case of transverse myelitis it seems

Thats an extremely rare disease, 1400 cases a year in the US out of 300 million people

Odds of that appearing twice in a phase 3 trial are astronomical, yet it happened

https://www.google.com/amp/s/www.telegraph.co.uk/news/2020/09/20/human-trials-oxford-vaccine-hold-us-spinal-cord-disease-fears/amp/

Deeper Blue · 20-09-2020 04:57PM

Thierry12 wrote: »

Oxford one in big trouble

Another case of transverse myelitis it seems

Thats an extremely rare disease, 1400 cases a year in the US out of 300 million people

Odds of that appearing twice in a phase 3 trial are astronomical, yet it happened

https://www.google.com/amp/s/www.telegraph.co.uk/news/2020/09/20/human-trials-oxford-vaccine-hold-us-spinal-cord-disease-fears/amp/

There's absolutely nothing new in that article so maybe tone down the sensationalism a little bit

Azatadine · 20-09-2020 05:02PM

Maybe a stupid question but what is the reason for some of these posters that post absolute doom mongering negative lies/misconstrues/false conclusions because they don't understand the facts? Why post stuff that they clearly do not understand? Makes no sense to me.

Jinglejangle69 · 20-09-2020 05:03PM

Anyone see the video of the Oliver bond flats last night?

You will, all I'll say is we are never getting out of these restrictions here with the amount of morons out there.

Rave on the astro pitch with about 300 youths.

Thierry12 · 20-09-2020 05:03PM

El Sueño wrote: »

There's absolutely nothing new in that article so maybe tone down the sensationalism a little bit

2 people of which are 2 british women, have got an extremely rare disease in a clinic trial for a vaccine

How is that not nothing new?

How is it sensationalism?

MerlinSouthDub · 20-09-2020 05:04PM

Thierry12 wrote: »

2 people of which are 2 british women, have got an extremely rare disease in a clinic trial for a vaccine

How is that not nothing new?

How is it sensationalism?

The 1st case was caused by MS.

Deeper Blue · 20-09-2020 05:08PM

Thierry12 wrote: »

2 people of which are 2 british women, have got an extremely rare disease in a clinic trial for a vaccine

And it's been decided that the trials are ok to continue because these were presumably unrelated to the vaccine. I expect the US will soon restart the trials also.

Thierry12 wrote: »

How is that not nothing new?

It's been reported on and discussed at length before on this thread and possibly the main thread.

Thierry12 wrote: »

How is it sensationalism?

Saying "Oxford vaccine in big trouble" when there's no evidence of that would be considered by most to be sensationalist.

Thierry12 · 20-09-2020 05:11PM

MerlinSouthDub wrote: »

The 1st case was caused by MS.

We have 2 now, if it gets a 3rd it cant be statistical coincidence

They've stopped the trial again anyway, probably getting all British women off it ;-)

COVID-19: Vaccine/antidote and testing procedures Megathread [Mod Warning - Post #1]

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