COVID-19: Vaccine and testing procedures Megathread Part 3 - Read OP

Cork2021

Would anyone be thinking along the same lines as me that it’ll be the 16-44 year olds for the J&J and some AZ? This will speed up the stop of spread in the younger cohorts as that is where the majority of cases are coming from?

stefanovich

SusanC10 wrote: »

Apologies if this has been posted already but good news from Pfizer on kids age 12+.

https://www.euronews.com/2021/03/31/pfizer-biontech-says-their-vaccine-had-100-efficacy-in-trial-of-children-aged-12-15

Any idea on when the EMA will approve for aged 12+?

I'd wait for approval before getting too excited.

https://www.justice.gov/sites/default/files/usao-ma/legacy/2012/10/09/Pfizer%20-%20PR%20%28Final%29.pdf

timbel

Chris_5339762 wrote: »

Update: Talking to a family friend who uses the same GP practice, he is 77 and hasn't had his first dose yet, he's also been told two weeks before there is any delivery to the practice at all.


So my 73 and 74 year old parents, at a wild guess, will now be at the end of April, despite all the promises about "first dose before mid April". This is a big GPs practice by the way, nothing out of the ordinary.

Similar story here, my dad 76 registered on the GP’s portal 1.5months ago (based in D24). Still no sign of appointment for first dose. Very frustrating when you see others receiving 2nd doses already.

josip

Cork2021 wrote: »

Would anyone be thinking along the same lines as me that it’ll be the 16-44 year olds for the J&J and some AZ? This will speed up the stop of spread in the younger cohorts as that is where the majority of cases are coming from?

I doubt if they'll differentiate by age.

AZ single dose efficacy is the same as J&J so it doesn't matter which one is used.
Pfizer is almost 60% effective after a first dose I think.

stefanovich

stefanovich wrote: »

I'd wait for approval before getting too excited.

https://www.justice.gov/sites/default/files/usao-ma/legacy/2012/10/09/Pfizer%20-%20PR%20%28Final%29.pdf

Relevance of what Pfizer did 15 years ago to a vaccine developed by a different company?

ddarcy

iamwhoiam wrote: »

Are you sure ? Family members Type 1 with very controlled levels ?
Attending Tallaght hospital

Yeah Sligo/Mayo/Galway have all done it. Heard same with Kerry/cork/clonmel too. Dublin seems to be an outlier though.

Like my HBA1C is 5.8 old money, perfect control etc and they moved me up. Diabetic nurse told me everyone was moved from the clinic as HSE changed guidelines

ACitizenErased

Vaccine passport is in prototype stage within the HSE - a number of workers at CUH got signed up to it today

funnydoggy

ACitizenErased wrote: »

Vaccine passport is in prototype stage within the HSE - a number of workers at CUH got signed up to it today

How tamper-proof is it? Having a discussion with someone on reddit who won't take the vaccine but will buy it a vaccine passport off the black market and do whatever he likes.

ACitizenErased

funnydoggy wrote: »

How tamper-proof is it? Having a discussion with someone on reddit who won't take the vaccine but will buy it a vaccine passport off the black market and do whatever he likes.

It’s an app

funnydoggy

ACitizenErased wrote: »

It’s an app

Ah good then!

crossman47

plodder wrote: »

The one thing that I don't like about Karina Butler is when she says "we'd love to vaccinate everyone at the same time, but ...". I think most people get that everyone can't be vaccinated at the same time. It's a bit patronising.

Unfortunately theres a large group who see only the negative and they need to be told this will take a while. They're the group who, if told they would get free bread for the next year, would complain there was no jam. The practicalities must be spelt out especially as she was dealing with an interviewer who, like most in RTE, was just looking to catch her out. I think she is excellent, maybe the best of the medical communicators.

josip

ACitizenErased wrote: »

Vaccine passport is in prototype stage within the HSE - a number of workers at CUH got signed up to it today

For some reason I had thought it would be an EU-wide App.
Does this mean that each country can develop their own and border controls will have to be familiar with 27 different App layouts in various languages?
Or will QR code generation be centrally controlled by the EU?
I would worry that if it's up to each country to do their own, that our bunch of isolationists will undermine it subversively.
The same way they are doing it with the Passport Office.

LLMMLL

Type 1 diabetic, decent control here. Just got a text to get my vaccine next week.

It's the AZ one. What's the latest on this?
- what's the dosing schedule in Ireland? 8 or 12 weeks?
- what's the efficacy and what does this mean at an individual level?

josip

LLMMLL wrote: »

Type 1 diabetic, decent control here. Just got a text to get my vaccine next week.

It's the AZ one. What's the latest on this?
- what's the dosing schedule in Ireland? 8 or 12 weeks?
- what's the efficacy and what does this mean at an individual level?

12 weeks
85% 2-dose efficacy I believe, 100% against really bad sh1t happening.

JPup

LLMMLL wrote: »

Type 1 diabetic, decent control here. Just got a text to get my vaccine next week.

It's the AZ one. What's the latest on this?
- what's the dosing schedule in Ireland? 8 or 12 weeks?
- what's the efficacy and what does this mean at an individual level?

12 weeks and essentially 100% effective at preventing serious disease. Serious side effects are very rare. You can take it with confidence!

lbj666

LLMMLL wrote: »

Type 1 diabetic, decent control here. Just got a text to get my vaccine next week.

It's the AZ one. What's the latest on this?
- what's the dosing schedule in Ireland? 8 or 12 weeks?
- what's the efficacy and what does this mean at an individual level?

May depend of underlying conditions but 1st dose alone has a dramatic reduction in serious illness or hospital also

LLMMLL

JPup wrote: »

12 weeks and essentially 100% effective at preventing serious disease. Serious side effects are very rare. You can take it with confidence!

I'm confident about taking it. Just wondering how that 85% number should be interpreted at an individual level. I'm pretty sure it doesn't mean I'm 85% less likely to get it. Maybe there is no interpretation at an individual level.

Also the 100% figure seems to be based on 8 people in the placebo getting serious covid. Since that figure is so low, isn't it a bit glib to say it's 100% effective in preventing serious covid. If the overall study was twice as big, wouldn't it be possible that 16 people in the placebo group would get it and 1 in the "genuine vaccine" group would get it meaning lower than 100% efficacy?

Not trying to poke holes or be anti-vax in any way. Just curious about the facts.

IRISHSPORTSGUY

https://twitter.com/StZ_NEWS/status/1377274457748815874

Curevac boss Franz-Werner Haas: "We want to start vaccinating in June"

lbj666

LLMMLL wrote: »

I'm confident about taking it. Just wondering how that 85% number should be interpreted at an individual level. I'm pretty sure it doesn't mean I'm 85% less likely to get it. Maybe there is no interpretation at an individual level.

Also the 100% figure seems to be based on 8 people in the placebo getting serious covid. Since that figure is so low, isn't it a bit glib to say it's 100% effective in preventing serious covid. If the overall study was twice as big, wouldn't it be possible that 16 people in the placebo group would get it and 1 in the "genuine vaccine" group would get it meaning lower than 100% efficacy?

Not trying to poke holes or be anti-vax in any way. Just curious about the facts.

Is there not more info from the recent US trails aswell

Qrt

Prioritising the J&J vaccines to those more likely to be hard to track down would be a good move, particularly the travelling community given their literacy issues and general distrust of the state.

Bit iffy about the vaccine passport as an app, I'd much rather see it as a passport-card style NFC card, but I'd take an app as a short-term thing.

Theboinkmaster

Qrt wrote: »

Prioritising the J&J vaccines to those more likely to be hard to track down would be a good move, particularly the travelling community given their literacy issues and general distrust of the state.

I wouldn't be giving them any special treatment TBH. If they don't/can't take the vaccine leave them at it.

Corholio

Donnelly signing his new 3 year contract. Excited for the future and can't wait to get back on the pitch :P.

https://twitter.com/DonnellyStephen/status/1377298509431472133?s=19

titan18

AdamD wrote: »

This penny is going to drop soon. The government have also said that 2 'fully vaccinated' people can meet up 2 weeks after their second dose. That's 14 weeks after somebody gets their first AZ dose...

Ya, if countries are doing it like that. No one will want AZ. Whatever about side effects, no one is going to be interested if youre treated as non vaccinated for that long after it when it's 5 weeks with Pfizer or 2/3 weeks with Johnson and Johnson.

lbj666

Theboinkmaster wrote: »

I wouldn't be giving them any special treatment TBH. If they don't/can't take the vaccine leave them at it.

Problem is outbreaks in that community have residual impacts on the broader community, so fairness or deservedness doesn't come into it.

lbj666

titan18 wrote: »

Ya, if countries are doing it like that. No one will want AZ. Whatever about side effects, no one is going to be interested if youre treated as non vaccinated for that long after it when it's 5 weeks with Pfizer or 2/3 weeks with Johnson and Johnson.

I wouldn't worry about this too much, it's very much an interim measure. Once the vacine program has taken and clear hold on the epidemiological situation it won't be as big a deal.

Danzy

lbj666 wrote: »

Problem is outbreaks in that community have residual impacts on the broader community, so fairness or deservedness doesn't come into it.

Given the widespread attitude to Covid in the travelling community, the uptake on vaccines is going to be very small.

Strazdas

Latest stats are that we are vaccinating 17,500 people a day. That's not bad at all and very much going in the right direction.

Mike3549

donalsim wrote: »

First page of this thread hasn't aged too bad only 30% off MM projections from his speech in mid Feb.

Actualy less than 30%. We only have numbers up to sunday. Add another 50k vaccinated in 3 days and were only 22% off :-)

JPup

LLMMLL wrote: »

I'm confident about taking it. Just wondering how that 85% number should be interpreted at an individual level. I'm pretty sure it doesn't mean I'm 85% less likely to get it. Maybe there is no interpretation at an individual level.

Also the 100% figure seems to be based on 8 people in the placebo getting serious covid. Since that figure is so low, isn't it a bit glib to say it's 100% effective in preventing serious covid. If the overall study was twice as big, wouldn't it be possible that 16 people in the placebo group would get it and 1 in the "genuine vaccine" group would get it meaning lower than 100% efficacy?

Not trying to poke holes or be anti-vax in any way. Just curious about the facts.

More than 10 million people have taken the vaccine already in the UK and the incidence of serious illness after 3 weeks is very low. And that is without the 2nd dose in most cases. So it's not just relying on trial data any more. It has been shown to be safe and highly effective in the real world.

JPup

donalsim wrote: »

100% as in no one with that vaccine will ever end up in hospital or die?

Rounded to the nearest whole number (i.e. allowing for a very small number of exceptions) that is my understanding, yes.