COVID-19: Vaccine/antidote and testing procedures Megathread [Mod Warning - Post #1]

Really nice interview with Prof. Sahin for anyone who didn't see it.

https://news.sky.com/video/covid-19-ugur-sahin-of-biontech-says-the-vaccine-may-be-available-this-year-in-uk-to-combat-coronavirus-12130695

Down to earth genius, but likely to become one of the richest men in Germany, which is well earned. Still plans to cycle to work!

ShineOn7 wrote: »

Thanks

Best guess at when it'll be in Ireland? Q2 next year maybe?

That coupled with a vaccine rollout to the over 60s and Frontline workers by the end of Q2 2021 would be a seriously strong double punch to this b@stard

Whenever they get through the trials I suppose, so yeah probably Q2 or later.

Deleted User wrote: »

https://twitter.com/elonmusk/status/1327125840040169472?s=20

I'm sad to think I respected him before this pandemic.

If you'd read this thread you'd have seen some of the people who know what they are talking about saying that the current rapid antigen tests are unreliable, and why they haven't been recommended for use here.

Musk in his tweets later says he has potential symptoms.

Hmmzis wrote: »

Well, vaccines are supposes to induce GC creation if designed and dosed right (the complete oposite what the virus is doing).

As I say this is not my field of study but I am curious, and I have read a number or artciles around vaccination durability. I notice you keep mentioning HPV which has proven to be a success in terms of durability which is a win but I also read that there are a number of viruses that are hard to vaccinate against so we cannot use HPV as the litmus.


My understanding is natural immune response can fall into a number of categories and most vaccines will mimic the same immune response.


We don't have a vaccine for common colds because the virus can naturally be forgotton within week of infection so getting a long lasting vaccines for all the strains is seeminly huge task.


Some vaccines and viruses give life long immunity usually not gauranteed people on occastion do get the chicken pox twice but for the most part they don't.



Then we have things like a tetanus vaccine which lasts like 10 years and if you get a deep cut etc you will probably get the jab if you have not had one in a while.


So the actual virus seems to dictate to some degree the immute response which in turn seems to dictate or at least in part the durability and (theta) longevity of immunity.

Hmmzis wrote: »

That's most likely based off some observations they've done following up phase 1/2 participants and maybe some known models that look like a decent fit? Good enough for finger in the air tuff.

Yeah that makes sense - Risk models are complicated and you would be amazed at how they can change with more data that much I know a lot about.

Hmmzis wrote: »

As the article states, sensory neurons, that's very far from the brain. It's a very informative article, thank for posting it.

I actually remembered this being said in a lacture I just cannot find it so I am trying to remember was it the brain or the trigeminal ganglia which is basically located at the base of the skull so not that far at all.


The artcile when it talks about sensory neurons is refering to inital infection, so essentally your lips which makes sense but it goes on to say:



"When researchers examined the virus's behavior in cells obtained from clusters of nerve cells known as trigeminal ganglia" which seeminly orchastrates this dance of activation and hiberation.


here is a little video explanation:


https://www.youtube.com/watch?v=L_2rARaxhz4

polesheep wrote: »

Then you aren't discussing it with them. You won't persuade people easily if you don't listen to them. We all want to be heard. Why not give them a book on Edward Jenner for Christmas and have the discussion again in the new year?

I think people are buy into hard conspiricies with no real education or understanding of basic concepts are mentally ill, I know a number who do not believe in a single conspiricy but lots! You cannot resaon with unreasonable people. It's almost like trying to argue over religion!

ShineOn7 wrote: »

He's the world's wealthiest troll

I've lost so much respect for Musk in the last year or two

He's actually shown himself to be straight up evil. Deliberately misconstruing data and disseminating it on twitter, all so he can keep his manufacturing going and money rolling in.

ShowMeTheCash wrote: »

Then we have things like a tetanus vaccine which lasts like 10 years and if you get a deep cut etc you will probably get the jab if you have not had one in a while.

I've been often told that if you get a deep cut or bad open injury and end up in an emergency room at the hospital, they will give you a shot of tetanus vaccine regardless your current condition, because you could not have up to date your vaccination record with you, or you might not be in a physical state that you can tell them you have a valid vaccination.

polesheep wrote: »

I'm not suggesting that you can easily persuade an anti-vaxxer, but I don't believe that there are as many of those as is often made out. There is a tendency at the moment to lump everyone who has concerns around a new and hastily created vaccine in with the anti-vaxxers and then throw in things like 5G and other nonsense.

I agree with you polesheep, but I'm not trying to put anyone in boxes. It's just what I'm seeing at the moment - those who are the most vocal with regards to vaccines usually do at some point follow along with those kinda conspiracy theories.

polesheep wrote: »

I have a good understanding of how vaccines work and I am very pro-vaccine. I hope all of the current vaccines being worked on are very successful, for many reasons. But even if every related scientist in the world were working on them it would still be hasty and that is where concerns are naturally coming from. I'm quite confident, however, that we will have a safe vaccine with no real issues, but people's legitimate concerns must be addressed rationally and not be simply dismissed as anti-vaxx if the roll-out is to be a success.

You are making a claim here, what I am saying is your claim is based on a poor understanding of how vaccines are developed.