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Vaccine Megathread - See OP for threadbans

1457910199

Comments

  • Registered Users Posts: 15,302 ✭✭✭✭stephenjmcd


    rm212 wrote: »
    They’re large yes, but even in the most optimistic case of them being at the absolute maximum... it’s still not amazing protection. Especially for the severe infection.

    Well, we will see a real life example with the UK starting to re-open, I suppose.

    Theres been much discussion on that study previously.

    It's been riddled with issues since it was originally published. The dosing schedule is incorrect to start with, a 4 week schedule has already been proven not to be optimal for AZ & then recently there was talk of dodgy anti body tests having been used in SA.


  • Registered Users Posts: 2,065 ✭✭✭funnydoggy


    About the UK - Let's hope they don't see an increase in cases as a reason to tighten their restrictions. The vaccine goes beyond case numbers. I thought I read their CMO even said that there'll be an increase in cases but not hospitalisations or deaths so no need to panic.

    Some common sense IMO. If that was our lot and our cases increased, MM would be back on the podium with a solemn look on his face.


  • Registered Users Posts: 689 ✭✭✭rm212


    Theres been much discussion on that study previously.

    It's been riddled with issues since it was originally published. The dosing schedule is incorrect to start with, a 4 week schedule has already been proven not to be optimal for AZ & then recently there was talk of dodgy anti body tests having been used in SA.

    Ah ok, fair enough. The mRNA vaccines do have the major advantage of being exceedingly easy to make booster shots with any new variants, though. The viral vector technology is likely not as easily adaptable...


  • Registered Users, Registered Users 2 Posts: 19,161 ✭✭✭✭Strazdas


    rm212 wrote: »
    Australia have rejected J&J (after also suspending AZ) as they don’t want to use adenovirus vector vaccines due to the blood clotting concerns. Looks like they’ll be sticking to Pfizer and Moderna (and possible one or two others which are still in the pipeline)

    https://www.abc.net.au/news/2021-04-13/johnson-johnson-covid-19-vaccine-australia/100064454/

    Should be added that there is far less pressure on them - they only have a few cases a day and the country is effectively cut off from outside. It's much easier for them to be picky and choosy.


  • Registered Users Posts: 689 ✭✭✭rm212


    Strazdas wrote: »
    Should be added that there is far less pressure on them - they only have a few cases a day and the country is effectively cut off from outside. It's much easier for them to be picky and choosy.

    Yeah I did mention that in the other thread. If we weren’t so supply constrained, there’s no chance we’d use the AZ. We’d just go all in on Pfizer and Moderna instead as they are more effective, take less time between doses and they don’t have this CVST clotting issue - even with it being a low chance with AZ. So we’re only using it out of necessity.


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  • Posts: 0 [Deleted User]


    Astra is done guys.

    What an awful awful vaccine.

    Feel bad for anyone with a first dose but at least they had no side effects then they dodged the bullet. I Would not get the second dose and would wait till Pfizer comes available

    Measured statement :rolleyes:


  • Registered Users, Registered Users 2 Posts: 11,205 ✭✭✭✭hmmm


    I know the anti vaxxers are jumping on the bandwagon, but it's time now for cool heads and to keep vaccinating, and make sure no vaccine goes to waste. Both to protect us from this disease, and to get us back to normal life as soon as possible.

    https://twitter.com/KrutikaKuppalli/status/1381771928441122816?s=19


  • Registered Users, Registered Users 2 Posts: 4,239 ✭✭✭Sanjuro


    Sorry guys and girls. Can someone clarify for me. On one of the late night shows last night someone said all vaccinations are being suspended today until the HSE can sort out the new schedule. Did they mean AZ vaccinations or ALL vaccinations?


  • Registered Users, Registered Users 2 Posts: 1,305 ✭✭✭nibtrix


    obviously this has turned into a sh*tshow, no major surprise.

    What I cant understand is how there is talk of not using AZ tomorrow. surely they are not going to suspend them for over 60s tomorrow, then in a few days say ok its safe now roll uo your sleeves! I'm Irish people will accept this as we now are happy to take any sub par service and explanation available but to me its a joke to come out and say over 60s all good nothing to fear but oh hang on a few days just need to double check.

    Should open the portal tomorrow for over 60s to register for vaccine to show confidence in the vaccine and keep on track in the ultimate goal to get everyone vaccinated and open up - that is the goal i think though sometimes it seems that opening society and getting people back to work is nowhere on our agenda

    They are not suspended for over 60s today for medical reasons, but for logistics. The HSE need a day or two to work out scheduling, there wasn’t enough time after the official announcement yesterday evening for them to tailor the notifications for those due to receive AZ today, so that those under 60 would be cancelled and those over 60 would go ahead.

    As for opening the portal early, again they need time to plan the allocation of vaccine to centres based on the new recommendations before they can make appointments for people.


  • Registered Users, Registered Users 2 Posts: 2,021 ✭✭✭Miike


    Sanjuro wrote: »
    Sorry guys and girls. Can someone clarify for me. On one of the late night shows last night someone said all vaccinations are being suspended today until the HSE can sort out the new schedule. Did they mean AZ vaccinations or ALL vaccinations?

    https://twitter.com/HSELive/status/1381696755666931712


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  • Registered Users, Registered Users 2 Posts: 4,239 ✭✭✭Sanjuro


    Thanks Miike. Would have seemed insane to cancel everything.


  • Registered Users, Registered Users 2 Posts: 11,205 ✭✭✭✭hmmm


    The worst thing about this is the safety overkill from Western regulators is going to damage confidence throughout the world. The Oxford vaccine is the only affordable option for many poorer countries.


  • Registered Users, Registered Users 2 Posts: 1,305 ✭✭✭nibtrix


    Sanjuro wrote: »
    Thanks Miike. Would have seemed insane to cancel everything.

    Agreed, doesn’t the Pfizer vaccine have a limited lifetime once it’s been removed from the ultra-cold storage? So any that have already been delivered to GPs in the last day or two needs to be administered ASAP.


  • Registered Users, Registered Users 2 Posts: 12,855 ✭✭✭✭average_runner


    funnydoggy wrote: »
    About the UK - Let's hope they don't see an increase in cases as a reason to tighten their restrictions. The vaccine goes beyond case numbers. I thought I read their CMO even said that there'll be an increase in cases but not hospitalisations or deaths so no need to panic.

    Some common sense IMO. If that was our lot and our cases increased, MM would be back on the podium with a solemn look on his face.

    Remember also most haven't got their second dose of the vaccine over there


  • Registered Users, Registered Users 2 Posts: 17,076 ✭✭✭✭vienne86


    60 to 69 cohort have most grounds for grievance I think. Ultimately, for a number of reasons, I think most of us would prefer the Pfizer vaccine

    I'm in that cohort and have never been a fan of AZ because it seems to be useless against the variants. I really feel I'm being pushed into a corner and I'm pissed off.


  • Posts: 0 [Deleted User]


    vienne86 wrote: »
    I'm in that cohort and have never been a fan of AZ because it seems to be useless against the variants. I really feel I'm being pushed into a corner and I'm pissed off.

    Whats this now?


  • Registered Users, Registered Users 2 Posts: 5,963 ✭✭✭Chris_5339762


    Whats this now?


    Ignore it, it is effective!


  • Registered Users, Registered Users 2 Posts: 4,485 ✭✭✭harr


    All this is purely political between the EU and vaccine manufactures , surely any covid deaths caused by this delay should outweigh the one in a million change of dying from a blood clot.. just can’t get my head around this decision.. it’s like it’s ok to have people die from covid but not from a clot ..


  • Posts: 0 [Deleted User]


    Ignore it, it is effective!

    Oh, I know, I would just like folks to backup the "statements of fact" on the vaccine against "variants" with reference to something other than a single under-powered study in relation to a single variant


  • Registered Users, Registered Users 2 Posts: 2,941 ✭✭✭dominatinMC


    hmmm wrote: »
    The worst thing about this is the safety overkill from Western regulators is going to damage confidence throughout the world. The Oxford vaccine is the only affordable option for many poorer countries.
    Maybe so, but Western regulators can afford (sort of) to be this cautious as we have the mRNA vaccines to rely on. A lot of third world countries don't have that luxury so they will have no choice but to crack on with AZ


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  • Registered Users, Registered Users 2 Posts: 32,136 ✭✭✭✭is_that_so


    harr wrote: »
    All this is purely political between the EU and vaccine manufactures , surely any covid deaths caused by this delay should outweigh the one in a million change of dying from a blood clot.. just can’t get my head around this decision.. it’s like it’s ok to have people die from covid but not from a clot ..
    Apart from the emotional baggage of it there is no way to quantify that death claim. There might be an issue if it were Pfizer but seeing as AZ has performed so poorly in deliveries that effect is mitigated. I'd be inclined to back the medical call ,especially that they just don't know why it's happening. It's sensible and in 3 months they might know more.


  • Registered Users Posts: 2,065 ✭✭✭funnydoggy


    So what's it gonna be today lol?


  • Registered Users, Registered Users 2 Posts: 32,136 ✭✭✭✭is_that_so


    Maybe so, but Western regulators can afford (sort of) to be this cautious as we have the mRNA vaccines to rely on. A lot of third world countries don't have that luxury so they will have no choice but to crack on with AZ
    A lot more can be learnt by others about the issue from this stance.


  • Registered Users, Registered Users 2 Posts: 11,675 ✭✭✭✭ACitizenErased


    vienne86 wrote: »
    I'm in that cohort and have never been a fan of AZ because it seems to be useless against the variants. I really feel I'm being pushed into a corner and I'm pissed off.
    Sorry but that's just complete nonsense


  • Registered Users Posts: 15,302 ✭✭✭✭stephenjmcd


    funnydoggy wrote: »
    So what's it gonna be today lol?

    180k won't be met this week is probably about all we'll hear.

    I'd say it'll be tomorrow before whatever changes in rollout are announced


  • Registered Users, Registered Users 2 Posts: 2,941 ✭✭✭dominatinMC


    Oh, I know, I would just like folks to backup the "statements of fact" on the vaccine against "variants" with reference to something other than a single under-powered study in relation to a single variant
    You'd nearly feel sorry for some posters on here, spouting ill-informed nonsense as fact. In most cases, they have probably looked at a headline on TheJournal.ie (or worse, RTE!) without any further reading on the topic, and drawn their own conclusions. Victims of clickbait culture, hook, line, and sinker.

    I've said it many times on previous incarnations of this thread, the media have been an absolute disgrace during all of this. Actively seeking-out worst case scenarios to suit their agenda. Those familiar with this thread know that there is plenty to be positive about, but you wouldn't think so if you were soley informed by our media. I don't indulge in schadenfreude, but I wouldn't be overly disappointed to see some of our news outlets close their doors when the covid gravy train runs dry.


  • Registered Users Posts: 2,065 ✭✭✭funnydoggy


    180k won't be met this week is probably about all we'll hear.

    I'd say it'll be tomorrow before whatever changes in rollout are announced


    I could do with a drama-free day alright.


  • Registered Users Posts: 5,917 ✭✭✭Wolf359f


    harr wrote: »
    All this is purely political between the EU and vaccine manufactures , surely any covid deaths caused by this delay should outweigh the one in a million change of dying from a blood clot.. just can’t get my head around this decision.. it’s like it’s ok to have people die from covid but not from a clot ..

    Would it also be political between the UK, Norway, Canada, Australia etc... and vaccine manufacturers?


  • Posts: 0 [Deleted User]


    180k won't be met this week is probably about all we'll hear.

    I'd say it'll be tomorrow before whatever changes in rollout are announced

    This is by far and a way the most annoying aspect - the impact to the rollout should have been assessed and a plan in place prior to the announcement from NIAC. HSE, NPHET and NIAC were all at the press conference so should have been possible. This colander like leaking of information that seeps out bit by bit resulting in partial information making its way to RTE early yesterday leads to increasing uncertainty, anxiety and allowing misinformation the spread in the absence of a clear message. When the full guidance was revealed, the absence of a clear plan also allows the misinformation fill the vacuum. We see it in the thread where the bulk of people actively seek to inform themselves yet we have loads of misinformation proliferating. Imagine what its like for those only receiving information through Karen on Facebook only


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  • Registered Users, Registered Users 2 Posts: 3,181 ✭✭✭patnor1011


    I guess that I wil wait for more studies particularly possible long time effect and delayed response. Folks at Harvard and MIT seems to stumbled onto something.

    Researchers from Harvard University and the Massachusetts Institute of Technology (MIT) are warning that the messenger RNA (mRNA) technology used in Wuhan coronavirus (Covid-19) “vaccines” has the capability to forever alter recipients’ genomic DNA, making them more susceptible to disease and death.

    Their December preprint paper contains findings about wild coronaviruses that challenge the CDC’s (Centers for Disease Control and Prevention) narrative that synthetic mRNA from Chinese virus injections cannot enter cell nuclei where DNA resides. It also questions the CDC claim that cells get rid of this synthetic mRNA “soon after it is finished using the programmed instructions.”

    “Under ordinary circumstances, the body makes (‘transcribes’) mRNA from the DNA in a cell’s nucleus. The mRNA then travels out of the nucleus into the cytoplasm, where it provides instructions about which proteins to make,” explains Children’s Health Defense (CHD) about how the process works naturally.

    “By comparison, mRNA vaccines send their chemically synthesized mRNA payload (bundled with spike protein-manufacturing instructions) directly into the cytoplasm,” it adds about how the synthetic mRNA found in Wuhan flu shots functions.

    Biochemist and molecular biologist Doug Corrigan, PhD, and his team say they were perplexed as to why many people who had already been injected for Chinese germs with synthetic mRNA still tested “positive” for them later on down the road. What they ultimately determined is that mRNA “vaccines” may be permanently altering human DNA through reverse transcription.

    Their paper explains that SARS-CoV-2 RNA s “can be reverse transcribed in human cells,” contrary to what the CDC claims. Further, “these DNA sequences can be integrated into the cell genome and subsequently be transcribed,” this being a phenomenon known as “retro-integration.”

    n Corrigan’s view, the information contained in his preprint “validates that this is at least plausible, and most likely probable.” The DNA-to-mRNA pathway is not a one-way street like the CDC claims. Reverse transcriptase enzymes do, in fact, have the ability to convert RNA into DNA, which can then integrate back into cell nuclei DNA. More than 40 percent of mammalian genomes, it turns out, comprise the products of reverse transcription.

    “The preliminary evidence cited by the Harvard-MIT researchers indicates that endogenous reverse transcriptase enzymes may facilitate reverse transcription of coronavirus RNAs and trigger their integration into the human genome,” CHD explains.

    The potential result of this, Corrigan and his team warn, is “a more severe immune response” among the “vaccinated” when they are exposed to wild-type illness – think cytokine storm or autoimmune disease.

    https://sciencewithdrdoug.com/2020/11/27/will-an-rna-vaccine-permanently-alter-my-dna/

    https://sciencewithdrdoug.com/2021/02/15/breaking-study-sheds-more-light-on-whether-an-rna-vaccine-can-permanently-alter-dna/


  • Registered Users, Registered Users 2 Posts: 826 ✭✭✭adam240610


    Everyone panicking and calling the astra vaccine ****e and useless need to calm down a bit. Seemingly there's around a one in a million chance of developing a fatal clot from a first dose of the vaccine, which would correspond to maybe one or two people in the entire country considering how much work BioNtech and others are putting up.

    Covid has killed thousands in Ireland, and not using these vaccines to save one or two lives will most definitely lead to a greater number of deaths, not to mention the increased economic impact of delaying the rollout.

    There's a lot of hyperbole and incorrect statements going around in this thread at the minute, giving out this vaccine as it comes in has a net positive on the number of lives saved overall. If we really wanted to stay somewhat cautious, which we should, giving astra to over 30s or 40s wouldn't affect the rollout time at all, but over 60 seems like overkill


  • Registered Users, Registered Users 2 Posts: 6,561 ✭✭✭Micky 32


    Whats this now?


    No matter how you try to educate the ignorant or clueless they’ll still never get it.


  • Registered Users, Registered Users 2 Posts: 14,380 ✭✭✭✭Professor Moriarty


    patnor1011 wrote: »
    I guess that I wil wait for more studies particularly possible long time effect and delayed response. Folks at Harvard and MIT seems to stumbled onto something.

    Researchers from Harvard University and the Massachusetts Institute of Technology (MIT) are warning that the messenger RNA (mRNA) technology used in Wuhan coronavirus (Covid-19) “vaccines” has the capability to forever alter recipients’ genomic DNA, making them more susceptible to disease and death.

    Their December preprint paper contains findings about wild coronaviruses that challenge the CDC’s (Centers for Disease Control and Prevention) narrative that synthetic mRNA from Chinese virus injections cannot enter cell nuclei where DNA resides. It also questions the CDC claim that cells get rid of this synthetic mRNA “soon after it is finished using the programmed instructions.”

    “Under ordinary circumstances, the body makes (‘transcribes’) mRNA from the DNA in a cell’s nucleus. The mRNA then travels out of the nucleus into the cytoplasm, where it provides instructions about which proteins to make,” explains Children’s Health Defense (CHD) about how the process works naturally.

    “By comparison, mRNA vaccines send their chemically synthesized mRNA payload (bundled with spike protein-manufacturing instructions) directly into the cytoplasm,” it adds about how the synthetic mRNA found in Wuhan flu shots functions.

    Biochemist and molecular biologist Doug Corrigan, PhD, and his team say they were perplexed as to why many people who had already been injected for Chinese germs with synthetic mRNA still tested “positive” for them later on down the road. What they ultimately determined is that mRNA “vaccines” may be permanently altering human DNA through reverse transcription.

    Their paper explains that SARS-CoV-2 RNA s “can be reverse transcribed in human cells,” contrary to what the CDC claims. Further, “these DNA sequences can be integrated into the cell genome and subsequently be transcribed,” this being a phenomenon known as “retro-integration.”

    n Corrigan’s view, the information contained in his preprint “validates that this is at least plausible, and most likely probable.” The DNA-to-mRNA pathway is not a one-way street like the CDC claims. Reverse transcriptase enzymes do, in fact, have the ability to convert RNA into DNA, which can then integrate back into cell nuclei DNA. More than 40 percent of mammalian genomes, it turns out, comprise the products of reverse transcription.

    “The preliminary evidence cited by the Harvard-MIT researchers indicates that endogenous reverse transcriptase enzymes may facilitate reverse transcription of coronavirus RNAs and trigger their integration into the human genome,” CHD explains.

    The potential result of this, Corrigan and his team warn, is “a more severe immune response” among the “vaccinated” when they are exposed to wild-type illness – think cytokine storm or autoimmune disease.

    https://sciencewithdrdoug.com/2020/11/27/will-an-rna-vaccine-permanently-alter-my-dna/

    https://sciencewithdrdoug.com/2021/02/15/breaking-study-sheds-more-light-on-whether-an-rna-vaccine-can-permanently-alter-dna/

    Both articles are simply idle speculation. From the second article:

    "Again, this is a theoretical exercise I am presenting for consideration. I am not making the claim that an mRNA vaccine will permanently alter your genomic DNA, and I didn’t make this claim in my first article, although it appears that troll sites made the fallacious claim that I did."


  • Closed Accounts Posts: 2,910 ✭✭✭begbysback


    adam240610 wrote: »
    Everyone panicking and calling the astra vaccine ****e and useless need to calm down a bit. Seemingly there's around a one in a million chance of developing a fatal clot from a first dose of the vaccine, which would correspond to maybe one or two people in the entire country considering how much work BioNtech and others are putting up.

    Covid has killed thousands in Ireland, and not using these vaccines to save one or two lives will most definitely lead to a greater number of deaths, not to mention the increased economic impact of delaying the rollout.

    There's a lot of hyperbole and incorrect statements going around in this thread at the minute, giving out this vaccine as it comes in has a net positive on the number of lives saved overall. If we really wanted to stay somewhat cautious, which we should, giving astra to over 30s or 40s wouldn't affect the rollout time at all, but over 60 seems like overkill

    Nonsense, covids mortality rate on under 50s with no underlying conditions is so low that it’s it not worth the risk of taking az


  • Registered Users, Registered Users 2 Posts: 7,657 ✭✭✭Doctor Jimbob


    patnor1011 wrote: »
    I guess that I wil wait for more studies particularly possible long time effect and delayed response. Folks at Harvard and MIT seems to stumbled onto something.

    Researchers from Harvard University and the Massachusetts Institute of Technology (MIT) are warning that the messenger RNA (mRNA) technology used in Wuhan coronavirus (Covid-19) “vaccines” has the capability to forever alter recipients’ genomic DNA, making them more susceptible to disease and death.

    Their December preprint paper contains findings about wild coronaviruses that challenge the CDC’s (Centers for Disease Control and Prevention) narrative that synthetic mRNA from Chinese virus injections cannot enter cell nuclei where DNA resides. It also questions the CDC claim that cells get rid of this synthetic mRNA “soon after it is finished using the programmed instructions.”

    “Under ordinary circumstances, the body makes (‘transcribes’) mRNA from the DNA in a cell’s nucleus. The mRNA then travels out of the nucleus into the cytoplasm, where it provides instructions about which proteins to make,” explains Children’s Health Defense (CHD) about how the process works naturally.

    “By comparison, mRNA vaccines send their chemically synthesized mRNA payload (bundled with spike protein-manufacturing instructions) directly into the cytoplasm,” it adds about how the synthetic mRNA found in Wuhan flu shots functions.

    Biochemist and molecular biologist Doug Corrigan, PhD, and his team say they were perplexed as to why many people who had already been injected for Chinese germs with synthetic mRNA still tested “positive” for them later on down the road. What they ultimately determined is that mRNA “vaccines” may be permanently altering human DNA through reverse transcription.

    Their paper explains that SARS-CoV-2 RNA s “can be reverse transcribed in human cells,” contrary to what the CDC claims. Further, “these DNA sequences can be integrated into the cell genome and subsequently be transcribed,” this being a phenomenon known as “retro-integration.”

    n Corrigan’s view, the information contained in his preprint “validates that this is at least plausible, and most likely probable.” The DNA-to-mRNA pathway is not a one-way street like the CDC claims. Reverse transcriptase enzymes do, in fact, have the ability to convert RNA into DNA, which can then integrate back into cell nuclei DNA. More than 40 percent of mammalian genomes, it turns out, comprise the products of reverse transcription.

    “The preliminary evidence cited by the Harvard-MIT researchers indicates that endogenous reverse transcriptase enzymes may facilitate reverse transcription of coronavirus RNAs and trigger their integration into the human genome,” CHD explains.

    The potential result of this, Corrigan and his team warn, is “a more severe immune response” among the “vaccinated” when they are exposed to wild-type illness – think cytokine storm or autoimmune disease.

    https://sciencewithdrdoug.com/2020/11/27/will-an-rna-vaccine-permanently-alter-my-dna/

    https://sciencewithdrdoug.com/2021/02/15/breaking-study-sheds-more-light-on-whether-an-rna-vaccine-can-permanently-alter-dna/

    What in the feck is this gibberish?


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  • Registered Users Posts: 15,302 ✭✭✭✭stephenjmcd


    patnor1011 wrote: »
    I guess that I wil wait for more studies particularly possible long time effect and delayed response. Folks at Harvard and MIT seems to stumbled onto something.

    Researchers from Harvard University and the Massachusetts Institute of Technology (MIT) are warning that the messenger RNA (mRNA) technology used in Wuhan coronavirus (Covid-19) “vaccines” has the capability to forever alter recipients’ genomic DNA, making them more susceptible to disease and death.

    Their December preprint paper contains findings about wild coronaviruses that challenge the CDC’s (Centers for Disease Control and Prevention) narrative that synthetic mRNA from Chinese virus injections cannot enter cell nuclei where DNA resides. It also questions the CDC claim that cells get rid of this synthetic mRNA “soon after it is finished using the programmed instructions.”

    “Under ordinary circumstances, the body makes (‘transcribes’) mRNA from the DNA in a cell’s nucleus. The mRNA then travels out of the nucleus into the cytoplasm, where it provides instructions about which proteins to make,” explains Children’s Health Defense (CHD) about how the process works naturally.

    “By comparison, mRNA vaccines send their chemically synthesized mRNA payload (bundled with spike protein-manufacturing instructions) directly into the cytoplasm,” it adds about how the synthetic mRNA found in Wuhan flu shots functions.

    Biochemist and molecular biologist Doug Corrigan, PhD, and his team say they were perplexed as to why many people who had already been injected for Chinese germs with synthetic mRNA still tested “positive” for them later on down the road. What they ultimately determined is that mRNA “vaccines” may be permanently altering human DNA through reverse transcription.

    Their paper explains that SARS-CoV-2 RNA s “can be reverse transcribed in human cells,” contrary to what the CDC claims. Further, “these DNA sequences can be integrated into the cell genome and subsequently be transcribed,” this being a phenomenon known as “retro-integration.”

    n Corrigan’s view, the information contained in his preprint “validates that this is at least plausible, and most likely probable.” The DNA-to-mRNA pathway is not a one-way street like the CDC claims. Reverse transcriptase enzymes do, in fact, have the ability to convert RNA into DNA, which can then integrate back into cell nuclei DNA. More than 40 percent of mammalian genomes, it turns out, comprise the products of reverse transcription.

    “The preliminary evidence cited by the Harvard-MIT researchers indicates that endogenous reverse transcriptase enzymes may facilitate reverse transcription of coronavirus RNAs and trigger their integration into the human genome,” CHD explains.

    The potential result of this, Corrigan and his team warn, is “a more severe immune response” among the “vaccinated” when they are exposed to wild-type illness – think cytokine storm or autoimmune disease.

    https://sciencewithdrdoug.com/2020/11/27/will-an-rna-vaccine-permanently-alter-my-dna/

    https://sciencewithdrdoug.com/2021/02/15/breaking-study-sheds-more-light-on-whether-an-rna-vaccine-can-permanently-alter-dna/

    What an utter load of crap.

    Refers to covid vaccines as the "wuhan flu shot" & refers to covid as "Chinese germs"

    That whole thing is some pile of anti vax crap.


  • Registered Users, Registered Users 2 Posts: 7,657 ✭✭✭Doctor Jimbob


    What an utter load of crap.

    Refers to covid vaccines as the "wuhan flu shot" & refers to covid as "Chinese germs"

    That whole thing is some pile of anti vax crap.

    You mean an article completely lacking citations on a website called science with Dr. Doug isn't legitimate? I need to reevaluate my sources.


  • Registered Users, Registered Users 2 Posts: 6,561 ✭✭✭Micky 32


    What in the feck is this gibberish?

    I think it’s just some whatsapp template and memo rubbish the anti vaxxers that are sending to each other.


  • Registered Users Posts: 2,065 ✭✭✭funnydoggy


    A nice read:

    Doug Corrigan pushing bad science and anti-vax tropes about mRNA vaccines


    https://www.skepticalraptor.com/skepticalraptorblog.php/doug-corrigan-pushing-bad-science-and-anti-vax-tropes-about-mrna-vaccines/


  • Registered Users, Registered Users 2 Posts: 32,136 ✭✭✭✭is_that_so


    adam240610 wrote: »
    Everyone panicking and calling the astra vaccine ****e and useless need to calm down a bit. Seemingly there's around a one in a million chance of developing a fatal clot from a first dose of the vaccine, which would correspond to maybe one or two people in the entire country considering how much work BioNtech and others are putting up.

    Covid has killed thousands in Ireland, and not using these vaccines to save one or two lives will most definitely lead to a greater number of deaths, not to mention the increased economic impact of delaying the rollout.

    There's a lot of hyperbole and incorrect statements going around in this thread at the minute, giving out this vaccine as it comes in has a net positive on the number of lives saved overall. If we really wanted to stay somewhat cautious, which we should, giving astra to over 30s or 40s wouldn't affect the rollout time at all, but over 60 seems like overkill
    AZ will finish its work for those already on one shot unless that health issue emerges. The positive from this is that AZ has now been assigned to one age category. We won't get to the 30s and 40s for quite some time, now looking more like July. By then we'll have a lot more Pfizer, J&J, Moderna and probably CureVac.


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  • Registered Users Posts: 15,302 ✭✭✭✭stephenjmcd


    You mean an article completely lacking citations on a website called science with Dr. Doug isn't legitimate? I need to reevaluate my sources.

    There's a market for science with Doctor Jimbob if you really want to push the boat out


  • Registered Users, Registered Users 2 Posts: 14,154 ✭✭✭✭josip


    hmmm wrote: »
    The worst thing about this is the safety overkill from Western regulators is going to damage confidence throughout the world. The Oxford vaccine is the only affordable option for many poorer countries.

    There is also Sinopharm although its efficacy is less than AZ.
    A relative tested positive for Covid yesterday, 4 weeks after her 2nd Sinopharm dose, quite a common occurrence.
    Mild, cold-like symptoms only.


  • Registered Users Posts: 2,065 ✭✭✭funnydoggy


    There's a market for science with Doctor Jimbob if you really want to push the baot out

    What about me?:pac:


    "Pretending to do science with funnydog" sounds quite lovely. I'd read it:o


  • Registered Users, Registered Users 2 Posts: 2,021 ✭✭✭Miike


    patnor1011 wrote: »
    I guess that I wil wait for more studies particularly possible long time effect and delayed response. Folks at Harvard and MIT seems to stumbled onto something.

    Researchers from Harvard University and the Massachusetts Institute of Technology (MIT) are warning that the messenger RNA (mRNA) technology used in Wuhan coronavirus (Covid-19) “vaccines” has the capability to forever alter recipients’ genomic DNA, making them more susceptible to disease and death.

    Their December preprint paper contains findings about wild coronaviruses that challenge the CDC’s (Centers for Disease Control and Prevention) narrative that synthetic mRNA from Chinese virus injections cannot enter cell nuclei where DNA resides. It also questions the CDC claim that cells get rid of this synthetic mRNA “soon after it is finished using the programmed instructions.”

    “Under ordinary circumstances, the body makes (‘transcribes’) mRNA from the DNA in a cell’s nucleus. The mRNA then travels out of the nucleus into the cytoplasm, where it provides instructions about which proteins to make,” explains Children’s Health Defense (CHD) about how the process works naturally.

    “By comparison, mRNA vaccines send their chemically synthesized mRNA payload (bundled with spike protein-manufacturing instructions) directly into the cytoplasm,” it adds about how the synthetic mRNA found in Wuhan flu shots functions.

    Biochemist and molecular biologist Doug Corrigan, PhD, and his team say they were perplexed as to why many people who had already been injected for Chinese germs with synthetic mRNA still tested “positive” for them later on down the road. What they ultimately determined is that mRNA “vaccines” may be permanently altering human DNA through reverse transcription.

    Their paper explains that SARS-CoV-2 RNA s “can be reverse transcribed in human cells,” contrary to what the CDC claims. Further, “these DNA sequences can be integrated into the cell genome and subsequently be transcribed,” this being a phenomenon known as “retro-integration.”

    n Corrigan’s view, the information contained in his preprint “validates that this is at least plausible, and most likely probable.” The DNA-to-mRNA pathway is not a one-way street like the CDC claims. Reverse transcriptase enzymes do, in fact, have the ability to convert RNA into DNA, which can then integrate back into cell nuclei DNA. More than 40 percent of mammalian genomes, it turns out, comprise the products of reverse transcription.

    “The preliminary evidence cited by the Harvard-MIT researchers indicates that endogenous reverse transcriptase enzymes may facilitate reverse transcription of coronavirus RNAs and trigger their integration into the human genome,” CHD explains.

    The potential result of this, Corrigan and his team warn, is “a more severe immune response” among the “vaccinated” when they are exposed to wild-type illness – think cytokine storm or autoimmune disease.

    https://sciencewithdrdoug.com/2020/11/27/will-an-rna-vaccine-permanently-alter-my-dna/

    https://sciencewithdrdoug.com/2021/02/15/breaking-study-sheds-more-light-on-whether-an-rna-vaccine-can-permanently-alter-dna/

    What a load of absolute drivel. Anyone with leaving cert biology can explain the process of reverse transcription and what is required for that process. None of the components of which exist in vaccines or SARS-CoV-2.


  • Registered Users, Registered Users 2 Posts: 11,675 ✭✭✭✭ACitizenErased


    funnydoggy wrote: »
    Calling him a quack got me :pac:


  • Registered Users, Registered Users 2 Posts: 7,657 ✭✭✭Doctor Jimbob


    funnydoggy wrote: »
    What about me?:pac:


    "Pretending to do science with funnydog" sounds quite lovely. I'd read it:o

    No no, you need to make it sound believable to the average gullible person. Heavy use of capitals and claims to qualifications you may not have would help - for example something like "REAL SCIENCE with Professor funnydog"


  • Posts: 0 [Deleted User]


    patnor1011 wrote: »
    I guess that I wil wait for more studies particularly possible long time effect and delayed response. Folks at Harvard and MIT seems to stumbled onto something.

    Researchers from Harvard University and the Massachusetts Institute of Technology (MIT) are warning that the messenger RNA (mRNA) technology used in Wuhan coronavirus (Covid-19) “vaccines” has the capability to forever alter recipients’ genomic DNA, making them more susceptible to disease and death.

    Their December preprint paper contains findings about wild coronaviruses that challenge the CDC’s (Centers for Disease Control and Prevention) narrative that synthetic mRNA from Chinese virus injections cannot enter cell nuclei where DNA resides. It also questions the CDC claim that cells get rid of this synthetic mRNA “soon after it is finished using the programmed instructions.”

    “Under ordinary circumstances, the body makes (‘transcribes’) mRNA from the DNA in a cell’s nucleus. The mRNA then travels out of the nucleus into the cytoplasm, where it provides instructions about which proteins to make,” explains Children’s Health Defense (CHD) about how the process works naturally.

    “By comparison, mRNA vaccines send their chemically synthesized mRNA payload (bundled with spike protein-manufacturing instructions) directly into the cytoplasm,” it adds about how the synthetic mRNA found in Wuhan flu shots functions.

    Biochemist and molecular biologist Doug Corrigan, PhD, and his team say they were perplexed as to why many people who had already been injected for Chinese germs with synthetic mRNA still tested “positive” for them later on down the road. What they ultimately determined is that mRNA “vaccines” may be permanently altering human DNA through reverse transcription.

    Their paper explains that SARS-CoV-2 RNA s “can be reverse transcribed in human cells,” contrary to what the CDC claims. Further, “these DNA sequences can be integrated into the cell genome and subsequently be transcribed,” this being a phenomenon known as “retro-integration.”

    n Corrigan’s view, the information contained in his preprint “validates that this is at least plausible, and most likely probable.” The DNA-to-mRNA pathway is not a one-way street like the CDC claims. Reverse transcriptase enzymes do, in fact, have the ability to convert RNA into DNA, which can then integrate back into cell nuclei DNA. More than 40 percent of mammalian genomes, it turns out, comprise the products of reverse transcription.

    “The preliminary evidence cited by the Harvard-MIT researchers indicates that endogenous reverse transcriptase enzymes may facilitate reverse transcription of coronavirus RNAs and trigger their integration into the human genome,” CHD explains.

    The potential result of this, Corrigan and his team warn, is “a more severe immune response” among the “vaccinated” when they are exposed to wild-type illness – think cytokine storm or autoimmune disease.

    https://sciencewithdrdoug.com/2020/11/27/will-an-rna-vaccine-permanently-alter-my-dna/

    https://sciencewithdrdoug.com/2021/02/15/breaking-study-sheds-more-light-on-whether-an-rna-vaccine-can-permanently-alter-dna/

    That's a notorious anti-vax group.


  • Registered Users, Registered Users 2 Posts: 5,914 ✭✭✭Russman


    Man, I miss the old vaccines thread


  • Registered Users, Registered Users 2 Posts: 3,181 ✭✭✭patnor1011


    Both articles are simply idle speculation. From the second article:

    "Again, this is a theoretical exercise I am presenting for consideration. I am not making the claim that an mRNA vaccine will permanently alter your genomic DNA, and I didn’t make this claim in my first article, although it appears that troll sites made the fallacious claim that I did."

    That is science and how it works. Someone make claim and then others try to disprove it. So far nobody disproved fact that they mRNA may alter or "programming" may go wrong.

    Also we based a lot of our responses on idle speculations like how many people would die without lockdowns or how vaccines wil save us and how safe they are and then we have this which is not that "idle speculation" ....

    https://medalerts.org/vaersdb/findfield.php?TABLE=ON&GROUP1=CAT&EVENTS=ON&VAX=COVID19&VAXTYPES=COVID-19&VAXMAN=PFIZER/BIONTECH


  • Registered Users Posts: 2,065 ✭✭✭funnydoggy




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