COVID-19: Vaccine and testing procedures Megathread Part 3 - Read OP

Apogee

Apogee wrote: »

https://www.irishtimes.com/news/ireland/irish-news/rapid-covid-19-tests-to-be-used-in-monitoring-school-outbreaks-1.4497580

[Prof MacRaith] Interview with Katie Hannon here from Sat:
https://www.rte.ie/radio/radioplayer/html5/#/radio1/21915427

Quotes a number of 72,000 over 85s

72,000 over 85s reconfirmed here:

RT&#201 wrote: »

Speaking to RTÉ's Today with Claire Byrne, Dr Denis McCauley said that there are over 44,000 patients among the over 85s cohort to be vaccinated this week. Dr McCauley said there are around 72,000 patients in this age bracket to be vaccinated and that over 71,000 should be vaccinated by the end of this week.

Difference of 9,000 on original estimate by HSE.

wadacrack

I can see this happening, especially with the virus rising pretyy significantly again in Eastern Europe in particular.

https://twitter.com/FergalBowers/status/1366801606398914561

JacksonHeightsOwn

wadacrack wrote: »

I can see this happening, especially with the virus rising pretyy significantly again in Eastern Europe in particular.

https://twitter.com/FergalBowers/status/1366801606398914561

For a bunch of highly educated people, the ones in charge of this really couldn't organise a pi$$ up in a brewery.

We all know months ago their approval process was taking too long..... They hardly need a review into it, sure the review itself would take another 5 months for them flutes

IRISHSPORTSGUY

wadacrack wrote: »

I can see this happening, especially with the virus rising pretyy significantly again in Eastern Europe in particular.

https://twitter.com/FergalBowers/status/1366801606398914561

Does it make a difference at this stage? J&J deliveries aren't arriving till April anyway.

I think the only time the conditional approval process was annoying was the wait for Pfizer. AZ and Moderna had such limited supply that it'd have made little difference if they were approved earlier.

User142

IRISHSPORTSGUY wrote: »

Does it make a difference at this stage? J&J deliveries aren't arriving till April anyway.

I think the only time the conditional approval process was annoying was the wait for Pfizer. AZ and Moderna had such limited supply that it'd have made little difference if they were approved earlier.

Probably to get CureVac into arms earlier and increase the speed the variant vaccine boosters get out.

Stark

There was meant to be an accelerated process for variant boosters anyway. Will Curevac be able to deliver if approval comes more quickly? I haven't been able to find any information on their manufacturing process.

Apogee

There are currently 435,895 doses administered as of Sat 27th. If 500,000 administered by Sun 7th, that comes to 64,005 for Sun 28th-Sun 7th. Seems low, even allowing for AZ 25,000 shortfall.

https://twitter.com/newschambers/status/1366793963156496385

is_that_so

Stark wrote: »

There was meant to be an accelerated process for variant boosters anyway. Will Curevac be able to deliver if approval comes more quickly? I haven't been able to find any information on their manufacturing process.

There is no data on Curevac yet, should be this month and the EMA are doing a rolling review of it. That will make it faster but still 2 weeks+. J&J will be nearly a month on 11 March.

trellheim

f 500,000 administered by Sun 7th, that comes to 64,005 for Sun 28th-Sun 7th. Seems low, even allowing for AZ 25,000 shortfall.

Roisin is correct - we are miles off planned deliveries - I pointed this out earlier. it should have been 624,000 by 28 Feb delivered. Moderna and AZ numbers seem way way off the pace. There is no public information on this.

Stark

is_that_so wrote: »

There is no data on Curevac yet, should be this month and the EMA are doing a rolling review of it. That will make it faster but still 2 weeks+. J&J will be nearly a month on 11 March.

Yeah I'm more curious as to if everything goes well with trials and approvals, how soon can doses actually start arriving.

is_that_so

Stark wrote: »

Yeah I'm more curious as to if everything goes well with trials and approvals, how soon can doses actually start arriving.

Well, they have a deal with Bayer to help up capacity. It was always at least Q2 anyway so April/May would be my guess. 405m on order for the EU.

Bigbooty

Pretty much got all the side effects about 14 hours after my AZ vaccine. Been sleeping after being sent home from work... should have called in sick really. A fair few people I know are in the same boat so I'd nearly take the day off after getting the AZ vaccine if you can just to recover properly.

eoinbn

is_that_so wrote: »

Well, they have a deal with Bayer to help up capacity. It was always at least Q2 anyway so April/May would be my guess. 405m on order for the EU.

June at the earliest. Their CEO is hoping for approval in June. Curevac won't be a factor this time around.

is_that_so

eoinbn wrote: »

June at the earliest. Their CEO is hoping for approval in June. Curevac won't be a factor this time around.

Well, they are supposed to have data this month.

Sweet.Science

Any update on current supply ? All in order or any setbacks etc

eoinbn

is_that_so wrote: »

Well, they are supposed to have data this month.

They will apparently release some data on variants - this will be from animal trials. This data will likely be positive otherwise they wouldnt release it.
The P2 results suggests that the vaccine itself isn't quite as effictive as BioNtech's. This surprised some people as Curevacs process is more advanced. However their dosage is only 40% of BioNtech's which might account for it.
They were only starting to enroll people in Belgium last week so they are months away yet.

Van.Bosch

trellheim wrote: »

Roisin is correct - we are miles off planned deliveries - I pointed this out earlier. it should have been 624,000 by 28 Feb delivered. Moderna and AZ numbers seem way way off the pace. There is no public information on this.

And potentially misleading info from Donnelly. “We received 520,000 doses (past tense) we will have given 500,000 (future) by the end of the week”

Sounds reasonable but if the 520, 000 were here last week but 100,000 more came in Wednesday then the 500,000 ain’t as good.

Micky 32

https://twitter.com/laoneill111/status/1366785207777517585?s=21

cameramonkey

Micky 32 wrote: »

https://twitter.com/laoneill111/status/1366785207777517585?s=21

People who have been exposed to sars1 seem to be immune from sars2 covid. They thing that the memory T cells are the responsible for the immune response that targets sars covid 2.



https://www.bmj.com/content/370/bmj.m3563

ninebeanrows

It will be amazing if the conspiracy theories around variants can be debunked in the coming weeks.

It could really be possible to have a decent summer if we can get hard facts to say current vaccines work to virtually eliminate hospitalization and death in all variants of the disease.

Miike

ninebeanrows wrote: »

It will be amazing if the conspiracy theories around variants can be debunked in the coming weeks.

It could really be possible to have a decent summer if we can get hard facts to say current vaccines work to virtually eliminate hospitalization and death in all variants of the disease.

Which conspiracy theories?

Water John

Miike wrote: »

Which conspiracy theories?

No, not here please.

Danzy

odyssey06 wrote: »

From RTE - note that Denmark also seem to be looking for any spare vaccines from Israel:

Austria has broken ranks with the European Union saying it would work together with Israel and Denmark to produce second-generation vaccines against mutations of the coronavirus. Chancellor Sebastian Kurz said Austria and Denmark, as members of the First Mover Group founded by him, would work with Israel on vaccine production against mutations of the coronavirus and jointly research treatment options. The announcement is a rebuke to the EU's joint vaccine procurement programme for member states which has been criticised for being too slow to agree deals with manufacturers.
https://www.rte.ie/news/coronavirus/2021/0302/1200326-coronavirus-global/

When the current procurement program doesn't take things serious, countries will have to walk from it and get the results.

Good to see this, gives us all more chances.

Danzy

is_that_so wrote: »

. At the very heart of this is vaccine nationalism and annoyance at the EU.

Many of the most prominent voices on this are from the most committed supporters of the EU.

It's hardly been a success, at any level.

hmmm

Danzy wrote: »

When the current procurement program doesn't take things serious, countries will have to walk from it and get the results.

Good to see this, gives us all more chances.

It seems a bit silly. Countries don't produce vaccines, vaccine manufacturers do. I'm not sure what Denmark & Austria hope to achieve.

If they wanted to short-circuit the process they'd either do side deals with manufacturers or bypass the EMA. I don't see either of these being a good option for small countries - bypassing the EMA is dangerous as regards confidence, and if you want to get into competition then the larger countries will win.

The reality I think is that the central EU purchasing is still the best deal for small countries. They just need to encourage changes to the procurement and authorisation processes to speed things up.

hmmm

https://twitter.com/POTUS/status/1366863233538228233

marno21

hmmm wrote: »

https://twitter.com/POTUS/status/1366863233538228233

Great news in that they will have surplus available which helps the worldwide pressure on demand.

If the US can start supplying Canada in June if frees up supply constraints in Europe. Pfizer can supply from Kalamazoo rather than using Puurs for example.

titan18

marno21 wrote: »

Great news in that they will have surplus available which helps the worldwide pressure on demand.

If the US can start supplying Canada in June if frees up supply constraints in Europe. Pfizer can supply from Kalamazoo rather than using Puurs for example.

I'm still worried they're going to be taking J &J supply from us.

irishgeo

titan18 wrote: »

I'm still worried they're going to be taking J &J supply from us.

Europe not just us.

braychelsea

marno21 wrote: »

Great news in that they will have surplus available which helps the worldwide pressure on demand.

If the US can start supplying Canada in June if frees up supply constraints in Europe. Pfizer can supply from Kalamazoo rather than using Puurs for example.

Also read that they have over 40 million doses of AstraZeneca stockpiled. Given they have enough supply from the MRNA vaccines I doubt they will even use any of the AZ vaccine.