COVID-19: Vaccine and testing procedures Megathread Part 3 - Read OP

WoollyRedHat

irishgeo wrote: »

3 weeks after the shot before it kicks in so the govt doesn't want everyone who is vaccinated swanning aroundthe place. Because they can be still infected. That's what happened in Israel.

Instead of treating people like children, could they not just simply state that and then launch a public health vaccination campaign to promote this message? It's 101.

lucernarian

astrofool wrote: »

I'd imagine we'll start seeing a whole cohort of people emerge with "underlying health conditions" making the order change a bit of a farce (and driven by politics rather than science...).

That's a pretty cynical view, given that NIAC has been mentioning specific conditions which appear to have clear diagnostic criteria.

It's good to see the proposals are being discussed and communicated to the public for this aspect of the rollout.

lucernarian

iamwhoiam wrote: »

I would think the very least you need is a GP or Consultants letter to be honest
The you hardly rock up and say I am a Type 1 diabetic

It's pretty easy to rock up with a prescription for those very specific meds + LTI book or card to prove it, but it's likely it will be GP-led like phase 3 currently is.

wadacrack

More promising data from Israel. Hopefully this will be replicated soon throughout Europe.

https://twitter.com/segal_eran/status/1363230475368677377

astrofool

lucernarian wrote: »

That's a pretty cynical view, given that NIAC has been mentioning specific conditions which appear to have clear diagnostic criteria.

It's good to see the proposals are being discussed and communicated to the public for this aspect of the rollout.

I would just be worried that we'll start seeing lots of articles about how bad some people have had it, and they deserve the vaccine, even if there's less at risk of dying than an older person (but more at risk than an average younger person). The order they had was based on risk, they are now changing it for, what seems like, some people not able to stick the restrictions for another couple of months, or being envious that an older person will have more freedom than they do.

RugbyLad11

Why don't they just give one pfizer dose to the non vunerable? I mentioned it a few weeks ago that it's better to get 10 people protected with 90% protect, instead of 5 people protected with 97% etc

ACitizenErased

RugbyLad11 wrote: »

Why don't they just give one pfizer dose to the non vunerable? I mentioned it a few weeks ago that it's better to get 10 people protected with 90% protect, instead of 5 people protected with 97% etc

You need to give the second dose for long term sustained protection.

iamwhoiam

lucernarian wrote: »

It's pretty easy to rock up with a prescription for those very specific meds + LTI book or card to prove it, but it's likely it will be GP-led like phase 3 currently is.

Which is why i said you would need a GP letter confirming your diagnosis . At least I would hope so to be honest .

RugbyLad11

ACitizenErased wrote: »

You need to give the second dose for long term sustained protection.

Surely that can be delayed a few months seen as they are already talking about booster shots in the winter.

ACitizenErased

RugbyLad11 wrote: »

Surely that can be delayed a few months seen as they are already talking about buster shots in the winter.

After 42 days the protection wanes so no not really

RugbyLad11

ACitizenErased wrote: »

After 42 days the protection wanes so no not really

Do you have a source for that? I'm not doubting you it's just the first time I've heard this.

ACitizenErased

RugbyLad11 wrote: »

Do you have a source for that? I'm not doubting you it's just the first time I've heard this.

No clinical confirmation of efficacy beyond 42 days.

https://www.ema.europa.eu/en/news/clarification-comirnaty-dosage-interval

WoollyRedHat

ACitizenErased wrote: »

No clinical confirmation of efficacy beyond 42 days.

https://www.ema.europa.eu/en/news/clarification-comirnaty-dosage-interval

We do have it though for AZ/Oxford vaccine though no?

ACitizenErased

WoollyRedHat wrote: »

We do have it though for AZ/Oxford vaccine though no?

Yes AZ is up to 12 weeks which is what is being followed

stephenjmcd

Not sure if posted this evening. Vaccine taskforce currently expect 600,000 doses of J&J vaccine in the second quarter, with delivery starting in early March pending approval

Cork2021

stephenjmcd wrote: »

Not sure if posted this evening. Vaccine taskforce currently expect 600,000 doses of J&J vaccine in the second quarter, with delivery starting in early March pending approval

That would be huge! That’s all the vulnerable vaccinated in double quick time, that’s 12% of the population done seriously fast.

Stheno

stephenjmcd wrote: »

Not sure if posted this evening. Vaccine taskforce currently expect 600,000 doses of J&J vaccine in the second quarter, with delivery starting in early March pending approval

I'm almost tearful at this news after all the doom and gloom this week

Thank you

BlondeLou

Is J&J one jab or two?

Cork2021

BlondeLou wrote: »

Is J&J one jab or two?

1 dose

NIMAN

To compare the North's vaccine roll-out versus the Souths, I am getting my 1st jab in the North this coming week as a carer of my mother.
In my early 50s. (in fact any carer >18yrs qualifies too).

Yet my near 80yr old mother-in-law in the South is still waiting.

Stheno

https://twitter.com/muirtheimhne/status/1363207807189872646?s=19

Cork2021

Article that Stephen is on about here. Over 1 million vaccines due each month in Q2

https://twitter.com/rtenews/status/1363222855849287684?s=21

Deeper Blue

Stheno wrote: »

https://twitter.com/muirtheimhne/status/1363207807189872646?s=19

While that's a lovely image and I appreciate the sentiment, I really think it needs to be hammered home to people that the vaccine doesn't offer significant protection until 2 weeks after getting it.

Just on the vaccine dosing thing, if UK data starts to show high level of antibodies/protection being sustained from single dose up to 12 weeks then everybody will shift to that strategy for Pfizer. It's a pity they haven't received any moderna yet, as I'm sure they would basically do the same for that and we'd find out if it works for that one too.

Stheno

El Sueño wrote: »

While that's a lovely image and I appreciate the sentiment, I really think it needs to be hammered home to people that the vaccine doesn't offer significant protection until 2 weeks after getting it.

Oh agreed no one knows the specifics if that was a grandparent who lives with the child

I've had a ****ty few days between being so busy in work that I've to work tomorrow and all the negativity

That tweet gave me hope, not that work will slow down, but that I might have some form of a life sooner rather than later

Polar101

ACitizenErased wrote: »

No clinical confirmation of efficacy beyond 42 days.

https://www.ema.europa.eu/en/news/clarification-comirnaty-dosage-interval

That doesn't sound the same as protection wanes after 42 days, it's just it hasn't been trialed.

..or?

Obviously not a great idea to delay beyond 42 days, though.

ACitizenErased

Polar101 wrote: »

That doesn't sound the same as protection wanes after 42 days, it's just it hasn't been trialed.

..or?

Obviously not a great idea to delay beyond 42 days, though.

Without clinic evidence the idea of waning immunity must be assumed.

WoollyRedHat

ACitizenErased wrote: »

Yes AZ is up to 12 weeks which is what is being followed

I'm wondering if the difference in vaccine technology for likes of AZ and Janssen is why there is longer-lasting efficacy after one dose, compared to the mRNA vaccines, anyone have any information on that hypothesis?

Polar101

Polar101 wrote: »

That doesn't sound the same as protection wanes after 42 days, it's just it hasn't been trialed.

..or?

Obviously not a great idea to delay beyond 42 days, though.

The longest dosing interval in the trial was 42 days, so there is no data on single dose protection levels after that time, it's unlikely protection just falls off a cliff. UK should be providing the data within the next 6 weeks or so.

WoollyRedHat

[Deleted User] wrote: »

The longest dosing interval in the trial was 42 days, so there is no data on single dose protection levels after that time, it's unlikely protection just falls off a cliff. UK should be providing the data within the next 6 weeks or so.

Is that being looked at as part of the challenge trials or real-life data?