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The Omicron variant

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Comments

  • Registered Users, Registered Users 2 Posts: 1,332 ✭✭✭ginoginelli


    I dont think he ever said it was flat out dangerous. More lets just wait for the evidence and see.

    The poster actually provides much needed balance form the deluded band of pollyannas that troll these boards daily.



  • Registered Users, Registered Users 2 Posts: 15,621 ✭✭✭✭Vicxas


    Its much more dangerous if you're not vaccinated. And SA has a 49% vaccination rate. So the deaths to vaccination ratio is still very good for a population of 60 million, 30 of those not fully vaccinated



  • Registered Users, Registered Users 2 Posts: 318 ✭✭RavenBea17b


    Long covid is an unknown and certainly not overestimated - many people have taken longer to recover, get back to a semblance of normal, only to relapse- not just anecdotal evidence. Long covid studies in UK are looking at this from a long term medical perspective - concern for long term care/impact to health service.



  • Registered Users, Registered Users 2 Posts: 295 ✭✭ShayNanigan


    Just read about a big research today that says every other adult who catches Covid is likely to have Long Covid. The symptoms are very varied as Covid causes inflammation in various organs. I'll have to see what I can find on it online.



  • Registered Users, Registered Users 2 Posts: 318 ✭✭RavenBea17b


    Long Covid is not just physical impact, the impact to social behaviour too - kids born during Covid social skills are different - studies looking at this, school and education lagging, mental stress. Impact of Covid is going to be felt in various ways, not just physical, of which the impact is still being evaluated, as more people report impact.



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  • Registered Users, Registered Users 2 Posts: 4,492 ✭✭✭McGiver


    Re fending off - I know one case of triple vaccinated 55 year old American male with Omicron in the US. No serious risk factors bar being overweight.

    His case seems to be "mild" similar to a bad cold or mild flu.



  • Registered Users, Registered Users 2 Posts: 4,492 ✭✭✭McGiver


    ~30% are caused by 4 HCov coronaviruses, which is still substantial. The immunity to them is estimated to last only 1 year or so. So what we observe with Sars-Cov-2 is quite in line with that.

    The reason why people get multiple colds is because they are caused by different viruses altogether or different HCov strains.

    I would also question the notion of "HCov viruses were initially also lethal" - can the OP present some genuine research on this?



  • Registered Users, Registered Users 2 Posts: 285 ✭✭boardlady


    I know multiple people, triple vaccinated, here, who have got omicron over the christmas period. Irrelevant, but none of them are particularly sick. The vaccinations do not prevent infection, just lessen the symptoms.



  • Registered Users, Registered Users 2 Posts: 1,353 ✭✭✭Le Bruise


    Out of interest, how did they know it was Omicron and not Delta? I'm only curious, as I assume they just give you a 'positive' or 'negative' for the virus, not which variant it is?



  • Registered Users, Registered Users 2 Posts: 7,632 ✭✭✭timmyntc


    Presumably because of 1) symptoms and 2) booster is less efficacious against omicron, so more likely that if you test positive from any, it would be omicron



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  • Registered Users, Registered Users 2 Posts: 6,626 ✭✭✭Micky 32




  • Registered Users, Registered Users 2 Posts: 3,328 ✭✭✭Banana Republic 1


    No both my parents have covid and it’s not a “cold”



  • Registered Users, Registered Users 2 Posts: 32,136 ✭✭✭✭is_that_so


    We've seen through this, that symptoms reported go from cold-like to something a whole lot more unpleasant. Omicron seems to report a lot more mild cold-like cases.



  • Registered Users, Registered Users 2 Posts: 1,787 ✭✭✭mohawk


    You want a credible source that at one time all other viruses that are known to commonly infect humans causing disease were at one time novel viruses that our ancestors immune systems were never previously exposed to and the weak wouldn’t have been able to fight off these novel viruses. You mightn’t agree but for me its a reasonable hypothesis. ‘cold’ viruses most likely wouldn’t have decimated populations to any great extent as there was a time in the not so distant past where it really was survival of the fittest for our ancestors.

    It can be argued that prior to modern medicine Covid-19 wouldn’t of been considered an epidemic or subsequently an pandemic as far less people lived to old age and many with chronic diseases or those who are immunocompromised wouldn’t have survived as long in the past.



  • Registered Users, Registered Users 2 Posts: 2,150 ✭✭✭TonyMaloney


    It could be argued, yes, just not successfully



  • Registered Users, Registered Users 2 Posts: 7,632 ✭✭✭timmyntc


    This misconception again - life expectancy being lower in the past did not mean that most people died off at 50 - plenty of people lived into 70s/80s/90s - its just that severe infant mortality dragged life expectancy way down.



  • Registered Users, Registered Users 2 Posts: 1,558 ✭✭✭Leftwaffe


    I’m sorry to hear that bit still personal abuse is not justified. Opinions are like arseholes, everyone has one.



  • Registered Users, Registered Users 2 Posts: 3,576 ✭✭✭VG31


    I don't believe long covid doesn't exist. But...the fact that we barely hear about it when the case numbers are high and when the case numbers drop it suddenly reappears is telling.



  • Registered Users, Registered Users 2 Posts: 2,150 ✭✭✭TonyMaloney


    Case numbers are pretty high right now and we're hearing about it



  • Registered Users, Registered Users 2 Posts: 1,291 ✭✭✭erlichbachman


    Well this is it folks, covid coming to an end with omicron, I know of about a handful of unvaccinated people with omicron and they wouldnt even think of taking time off work with the symptoms as they are so mild.

    Should we not now be planning an exit strategy, or is it too early?



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  • Registered Users, Registered Users 2 Posts: 1,787 ✭✭✭mohawk


    It’s not just about old age though is it? Obviously people lived to old age just not as many as now. Look at the diseases and chronic conditions people are living with today all thanks to modern medicine. I would guess nearly every poster on this board has family and friends who are alive today thanks to modern medicine. An example is to look at what a game changer insulin treatment was for those with diabetes.



  • Registered Users, Registered Users 2 Posts: 8,401 ✭✭✭corkie


    Omicron & The Endemic Phase of COVID | A Doctor Explains

    Dr. Zubin Damania, MD is a UCSF/Stanford-trained hospital doctor and host of The ZDoggMD Show, dedicated to Alt-Middle sense-making in healthcare and beyond.


    An actual MD for a change, as some people where taking issue with an educated (PhD) retired Nurse?


    Edit: -


    Post edited by corkie on

    ⓘ "At some point something inside me just clicked and I realized that I didn't have to deal with anyone's bullshit ever again."
    » “mundus sine caesaribus” «



  • Registered Users, Registered Users 2 Posts: 596 ✭✭✭deholleboom


    Good points. On the issue of lab escape: if true, you can be fairly sure these viruses came from captured wild animals and then lab tested for virus efficacy through maximisation of potential, ie, see what these babies could do under various conditions, first in vitro then in vivo, with...mice. It is with some irony that one of the potential starting points of Omicron is mice or hamsters. Im pretty sure the conspiracy crowd have already jumped on that one. From wild animals to lab mice to humans to mice and back to humans. Merrygoround, mutations galore.



  • Registered Users, Registered Users 2 Posts: 1,558 ✭✭✭Leftwaffe


    Maybe you should take a break from posting, you seem too angry to have any reasonable discussion.

    Anyway, ICU down to 84 this evening, 7 discharges 2 admissions. Once the legacy Delta patients are discharged this is over. Restrictions will no longer be justifiable. Normality will resume, can’t wait.



  • Registered Users, Registered Users 2 Posts: 596 ✭✭✭deholleboom


    Long Covid IS a thing with plenty of evidence. Before Omicron we saw the kind of cytokine storm/organising pneumonia affecting the lungs. As the lungs have a rather thin barrier between them and the blood the immune system inflammation often spread all over the body to the organs, the brain causing long term issues, ie long Covid. The good thing about Omicron that most of the viral reproduction stops at the upper respiratory level, at the bronchus so it really diminishes the long Covid aspect connected to lung inflammation.THAT is actually why it is considered milder as opposed to the vaccination and immunity factors having the biggest impact. Vaccines and boosters do help somewhat but it is, as i keep saying, a matter of small degrees in a multi factoral equation.

    But we are apparently children who shouldnt be bothered with all the complexities.



  • Registered Users, Registered Users 2 Posts: 4,492 ✭✭✭McGiver


    Oh yes no one disputes that. However vaccination can be a question of life and death in compromised or vulnerable individuals, even with Omicron.

    Saying that Omicron Cov-2 is a cold is dangerous propaganda and nonsense... It appears on this thread regularly.

    Cold doesn't kill people. Flu does, but in lesser numbers. Also, crucially, flu R0 is 1.3 whereas Omicron is >8, which is a huge difference.

    TLDR - it's not cold, it's super spreadable flu if people want to simplify into "buzzwords".



  • Registered Users, Registered Users 2 Posts: 3,328 ✭✭✭Banana Republic 1


    Maybe give that wooden gun and badge another coat varnish.



  • Registered Users, Registered Users 2 Posts: 4,492 ✭✭✭McGiver


    Long covid is not caused by systemic inflammation post infection as you suggest.

    ACE2 anti-type antibodies are implicated in long covid. Papers from prominent institutions are appearing.

    If we check what ACE2 receptors do and where in the body they exist, then we understand why this is an issue.

    Long covid is autoimmune mediated. This is NOT post-viral fatigue. It's directly linked to the spike protein, antibodies and anti-type antibodies attaching to ACE2 receptors and initiating inflammatory processes.



  • Registered Users, Registered Users 2 Posts: 8,401 ✭✭✭corkie


    Omicron growth for next two weeks

    Disclaimer for Channel: - He has a PhD to give him a Doctorate and is not an MD/GP etc.

    Hence title of 'Dr.', discussion in 'Will you be taking a booster?' thread.

    https://en.wikipedia.org/wiki/Doctor_(title)

    Poster in background explanation: - Interactions of health

    ⓘ "At some point something inside me just clicked and I realized that I didn't have to deal with anyone's bullshit ever again."
    » “mundus sine caesaribus” «



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  • Registered Users, Registered Users 2 Posts: 596 ✭✭✭deholleboom


    Thanks for your post. I do understand the function of ACE2 receptors. As far as i understand it the antibodies hook up to the virus spike proteins themselves to keep them from binding and not on the cells they try to invade via the ace2 receptors. The cytokine storm is the body going overboard with massive inflammation throughout the body to get rid of the antigens wherever they may be and i think a trigger to an evolving auto immune system just as i believe are post viral or post operative issues which are usually more than just chronic fatigue syndrom which can go on for years after the virus/antigen is gone. So, auto immune and inflammation goes hand in hand. Some of that is mast cell activation which i think i suffer from. All this a trigger mechanism without an antigen present. It is the body massively over reacting at first (cytokine storm) and then setting up a high sensitivity mechanism. Allergy is not a good word for it. Peanut allergy is just that, an allergy to a specific antigen. The rest is, as you stated, auto immune related and i include chronic fatigue syndrom etc in that. Now, here is where my knowledge ends. I think there is currently no evidence that Omicron will lead to long Covid because of the short time frame. If it continues not to we could conclude that long Covid must be linked to the effect of the first viral onslaught and huge inflammation by the immune system ( nose, throat and bronchi issues can be handled in the normal way like what happens in a cold).Antibodies and killer cells will clean up the antigens.Then it is up to mast and other cells in certain areas including deep in the bone marrow sensitive enough to get triggered.

    Sorry for the long and winding road

    Post edited by deholleboom on


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