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Would you be happy for your children to receive covid-19 vaccine

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Comments

  • Registered Users, Registered Users 2 Posts: 1,219 ✭✭✭Spudman_20000


    So Dr Lucy Jessop, director of the HSE’s National Immunisation Office has said there's 1 in 16,000 risk of myocarditis or pericarditis in boys. Neither of these conditions are insignificant. For me, the risks far outweigh the benefits for kids and quite frankly I'm amazed it has been approved for this age group at all unless there are serious underlying health conditions already.




  • Registered Users, Registered Users 2 Posts: 30,511 ✭✭✭✭Lumen


    I don't see why we shouldn't achieve or even exceed Canada's uptake of 73% in 12-17 ages, given that (I think) we've exceeded their take up in other age groups, which would add around 4% to our total population coverage, taking us to around 75% overall with the steady trickle from other age groups, perhaps by early October.

    https://health-infobase.canada.ca/covid-19/vaccination-coverage/#a5



  • Registered Users, Registered Users 2 Posts: 44 JEC


    All four Covid vaccines have received Conditional Marketing Authorisation from the EMA. This process is an expedited process, considerably shorter than traditional approval. CMA approval can be granted for medicines with less comprehensive medical data than would normally be required on the basis that the benefit of immediate availability outweighs the risk inherent in the fact that additional data is still required. There are specific obligations required of developers including the submission of monthly reports. Conditional Marketing Authorisation is valid for one year and can be renewed annually for up to 5 years.

    So while it is true to say that the vaccines are authorised for use in the EU I believe it is important to highlight to parents that they have not received standard marketing authorisation and are very much subject to ongoing trials and safety reviews, particularly in those under 16.



  • Registered Users, Registered Users 2 Posts: 30,511 ✭✭✭✭Lumen


    @JEC wrote

    the benefit of immediate availability outweighs the risk inherent in the fact that additional data is still required

    Couldn't agree more.



  • Posts: 265 ✭✭ [Deleted User]


    My child has also had all the vaccines as part of early childhood. I took a vaccine for malaria eight years ago myself. But there are clear differences in the current vaccines compared to past vaccines. You say you have no doubt in the safety of the vaccines. I do not share your certainty on this. Unless I am mistaken I find it very difficult to find information on the side effects of the vaccines currently. I know of two people who had very strong side effects, neither were given a follow up call by a doctor to see if they had side effects or not and neither thought of self reporting their side effects. So from what I can see we do not have good data in relation to the current side effects of the vaccines. I have asked my GP do we know if the vaccines are safe or not in the future and he said we do not know.



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  • Registered Users, Registered Users 2 Posts: 17,516 ✭✭✭✭Blazer


    and this is the key point most people miss out on.

    Covid is going to be here for a long time. Fair enough you get it once and its all good ie no ill effects etc , second time catching it ? slight fever maybe struggling for breath etc,,,,third time getting it? you could be goosed.

    So its a decision between taking a new vaccine which has the highest testing of any vaccines gone before it and lets be honest..there will be side effects...all drugs etc have side effects...

    but the question is do this risks outweigh the covid risks? For me I'll take the risk of the vaccines over the risks of Covid in my decision.



  • Posts: 265 ✭✭ [Deleted User]


    You say the goal is herd immunity (Which version of herd immunity are you talking about as the definition was changed by the WHO last year). This is baffling to me. I do not see this as the goal. If it was we need to nationalise the vaccination programs because for now rich countries are allowing poor countries to be the breeding ground for new variants, one which will eventually bypass vaccines. Also vaccines that keep hosts alive but still allow transmission could thus allow very virulent strains to circulate in a population.



  • Posts: 10,049 ✭✭✭✭ [Deleted User]


    Conditional Market Authorisation is a standard process



  • Registered Users, Registered Users 2, Paid Member Posts: 17,745 ✭✭✭✭astrofool


    Unless the variant doesn't use or significantly alters the spike protein (at which points it's essentially a new virus), vaccine escape is unlikely. Variants can be more transmissible or more deadly, but all share the spike or small variations of it because it's what makes SARS-COV2 so effective (while also being it's Achilles heal for vaccines).



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  • Registered Users, Registered Users 2 Posts: 44 JEC


    In a pandemic. It is not standard marketing authorisation. It is the EMA equivalent to the FDA's Emergency Use Authorization.



  • Posts: 10,049 ✭✭✭✭ [Deleted User]


    Its not - CMA is a standard approval mechanism that is in use for years and is used dozens of times every year. EUA is very different



  • Registered Users, Registered Users 2 Posts: 44 JEC


    CMA was introduced in 2006, in the ten years from 2006 30 products received CMA, 11 went on to receive standard authorisation. Two products were revoked, two swine flu pandemic vaccines.



  • Posts: 10,049 ✭✭✭✭ [Deleted User]




  • Registered Users, Registered Users 2 Posts: 44 JEC


    And we all know how that turned out.

    Approval for two swine flu vacvines, Arepanrix and Humenza, was withdrawn.

    I have no issue with the CMA of Covid vaccines but I think it is important that parents are fully informed that these vaccines have been approved with comprehensively less data than normally required for approval. They have not been subjected to the same approval process as all the other vaccines our children have received.

    They may be approved but the approval is conditional and only for one year at a time. There are absolutely no guarantees they will go on to receive standard marketing authorisation. They may well do but there is also a chance that they do not depending on the ongoing safety reviews. The point is we just do not know.



  • Registered Users, Registered Users 2 Posts: 7,236 ✭✭✭mcmoustache


    Raind already posted the link but I'll just spell out what's in there for those who worry about myocarditis as it seems to be the main concern about the vaccine.

    With the vaccine, there's a risk that children could develop myocarditis. With covid, there is six times the risk of developing myocarditis as well as god knows what else.

    I did some research recently and discovered that 6 is a lot bigger than one. I personally would prefer the option that comes with the least risk of myocarditis and that turns out to be the vaccine, remember 6 is bigger than 1, so big in fact that when you count with your fingers, it's on a completely different hand. If the vaccine were a game of Russian Roulette with a six-shooter and one bullet, covid would be like the same game with six bullets, one in each chamber, which if I'm honest would take a lot of the fun out of it.

    So if I had to choose between something with X risk of bad thing and 6X risk of bad thing, I would go with the first option myself.



  • Posts: 10,049 ✭✭✭✭ [Deleted User]


    Pandemrix received full approval, and issues still occurred. But the fact is that CMA does not permit the manufacturer to take short cuts on safety. The very first line on it is "the benefit-risk balance of the medicine is positive". Its also subject to enhanced ongoing monitoring requirements when approved as part of CMA. The implication that someone is at increased risk as a result of CMA is false.

    Its also worth bearing in mind that the issues with pandemrix occurred within 6 to 8 weeks of the doses being administered and the Covid vaccines are the most monitored in history with billions of doses administered already.

    There is also no history of vaccines having issues occur long after vaccination. Yet this is the spectre being presented here to parents, that because of a single vaccine which had extremely rare issues occur within weeks of been administered, these vaccines will have issues years into the future.

    Also worth noting on pandemrix - it was withdrawn not because the risks outweighted the benefits, but because alternatives were available with even lower risks



  • Registered Users, Registered Users 2 Posts: 4,182 ✭✭✭spaceHopper


    That is not fully true or even remotely true, the vaccines to date are as well tested as they can be under the circumstances but to the best of my limited knowledge they have been give "Conditional" approval due the urgent need caused by the pandemic, which I'm fine with but its not right for to say they are fully approved. You can't call people out for half truths and false statements and not apply the same standards to yourself especially when an admin of the site , please do better next time!

    Here's the official eu source.

    https://www.ema.europa.eu/en/medicines/human/EPAR/comirnaty#authorisation-details-section

    https://www.ema.europa.eu/en/human-regulatory/overview/public-health-threats/coronavirus-disease-covid-19/treatments-vaccines/covid-19-vaccines



  • Posts: 10,049 ✭✭✭✭ [Deleted User]


    Conditional approval is full approval, with conditions



  • Registered Users, Registered Users 2 Posts: 44 JEC


    Would you agree it is 'Conditional' because there is 'less complete data than normally required' as per the EMA's own website?

    The benefits may outweigh the risk in adults however this is much less clear cut in children. The assumption that most adverse effects are evident within 2 months of vaccinaton is based on existing vaccine technology however as Mrna vaccine technology has not been used in previous vaccines it is not clear that this assumption still applies.



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  • Posts: 10,049 ✭✭✭✭ [Deleted User]


    It wont be approved if the benefits don't outweigh the risk.

    And the "but but but mRNA" canard does not establish any mechanism by which something that will have long left the body will continue to cause impacts long into the future? With all vaccine technologies, long term events are caused by the bodies own immune system. mRMA does not cause myocarditis, the immune response does, adenovirus viral vector does not cause CVST the immune response does, pandemrix did not cause narcolepsy, the immune response did. Adenovirus is as new as mRNA as a vector, however it does not sound as "scary" so those spreading misinformation stick to the scary sounding mRNA in the hope that the uninformed think "mRNA, kind of like DNA, must be like GMO".



  • Registered Users, Registered Users 2 Posts: 42 123Dublin456


    I think herd immunity won't happen with this new strain, the vaccines will reduce transmission and then the majority unvaccinated group will be children. The measures should be gone soon because they were done to protect the vulnerable. I really think children should have some say in their own health and it shouldn't only be up to the parents but that's just my view. People keep mentioning low risk but I think if it did spread among all children then it could be different to what people expect because currently it's only been some. Who knows, I know I would personally want the vaccine. A lot of these side effects are difficult to even pin on the vaccine as tbe populations getting it are so huge.



  • Registered Users, Registered Users 2 Posts: 4,182 ✭✭✭spaceHopper



    I don't think we are done yet, we could well need boosters. Also covid and variants of it are here to stay, it will eventually melt into the background and become one of many vaccinated illness. Like the flu where they modify the vaccine based on what's seen in the southern hemisphere for us and then what we see for them each flu season.



  • Registered Users, Registered Users 2 Posts: 1,993 ✭✭✭FileNotFound


    I imagine your pretty on the ball with the future state there.

    We will even get to the point its voluntary shots if you want them (might even get a flu/covid jab in 1).



  • Registered Users, Registered Users 2 Posts: 44 JEC


    The fact remains that there is an assumption that Covid 19 vaccines have no long term side effects on children, despite the absence of any long term safety data.

    Many parents are happy to accept this assumption and vaccinate their children. There are others who will choose not to.

    I referred to mRNA technology only as it is only mRNA vacvines that are currently approved for use in children, adenovirus based vaccines are not. This is a fact not misinformation.



  • Posts: 10,049 ✭✭✭✭ [Deleted User]


    Children are humans too you know and the 12 months data since the trials started is a large amount of long term data. And before you say it - Pandemrix triggered narcolepsy in adults too and this presented within weeks of vaccination.

    And even so, they will not approve for even younger age groups without further supporting data



  • Registered Users, Registered Users 2 Posts: 42 123Dublin456


    I actually feel that its selfish to take a vaccine yourself but not get your child vaccinated. I don't really understand why people think the effects are going to be different for under 12s, usually vaccines are given to young children. The effects may generally be mild for 99 in 100 but for the 1 in 100 or so hospitalised, it's a different story. On one hand I understand the risk versus benefit analysis however I don't know if we fully understand covid enough to weigh up these risks of the virus. I've always felt these vaccines are for personal benefit and there is a bonus of a reduction of transmission. If people don't want that benefit then eventually there will be not much we can do, but I do think its strange to take vaccines yourself but then not allow your child to.



  • Registered Users, Registered Users 2 Posts: 383 ✭✭Unicorn Milk Latte


    Like in every profession, you find people who are excellent at their job as well as people who are terrible at their job amongst scientists and medical professionals. They are also just as susceptible to mental illness as people in any other profession.

    There are several common sense ways to evaluate scientists. What is their area of expertise? If an eye/foot/heart doctor who is not a scientist claims to know better than a virologist, that's a data point to evaluate. How much has a scientist published? How recently? How many times have his publications been cited?

    Scientists on top of their field publish a lot, get cited a lot, and have extensive credentials. An example of what credentials of a truly outstanding scientist look like can be found here.

    Publishing scientific papers is crucial for scientists - keeping findings secret would be equivalent to career suicide.

    Medical doctors, more often than not, are not scientists. Although they are often perfectly capable of understanding and communicating relevant science. Again, the field of expertise is a crucial indicator to evaluate what they have to say.


    The key characteristic of scientific work is that it is measurable, verifiable and reproducible - the opposite of an 'opinion', which is subjective and personal, and does not need to be reproducible or factually correct to be valid.



  • Registered Users, Registered Users 2 Posts: 44 JEC


    Most medicines have a different effect and safety profile for children and adults, even though we are all human. Why would anyone think it is safe to assume these vaccines don't?



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  • Registered Users, Registered Users 2 Posts: 1,993 ✭✭✭FileNotFound



    I think the word scientist is the worst word ever to be allowed in the public domain during times like these.

    I am by education and active profession a scientist and could spout my opinion on vaccines backed up by nice looking letters beside my name - alas I know no more than the daily person (I will say my company provides me with accurate info when it exists at least I suppose as they have a section involved in vaccine production).

    Unless your actively working in vaccine development, trials, production - odds are your far from the best source of anything specific. Even every tom dick and harry we get on the news - university professors (better known as failed pharma employees half the time) telling us nothing but generic nonsense and half statements.


    Anyway pointless rant over - Time to make a point.


    Would it not be wise to follow WHO advice and start to battle covid worldwide before children get vaccinated. This way we will have a lot more data to ensure things are safe for anyone who has concerns, even without kids we will hit the technical 70% herd figure, more international vaccination = less chance of variants. Just a thought...



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