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COVID-19: Vaccine/antidote and testing procedures Megathread [Mod Warning - Post #1]

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  • #5462
    Thierry12
    Closed Accounts Posts: 979 ✭✭✭Thierry12


    Water John wrote: »
    The Oxford vaccine is being offered at $4 and no refridgeration. Results in about a month.

    They won't let Pfzier have a free month

    Those in the know on Twitter said it was just as effective today

    We will get leaks

    Vaccine war has begun

    Some of those companies have waited whole lives for this


  • #5463
    mandrake04
    Registered Users, Registered Users 2 Posts: 4,435 ✭✭✭mandrake04


    Beanybabog wrote: »
    Why does the Pfizer vaccine need to be so cold? I’ve read numerous articles explaining the logistical challenges but not why it needs to be so cold. I read one that suggested the freezers can only be opened for a short amount of time... surely when you’re going to be injected the vaccine can’t be -80 (does it freeze?) so how do they manage to make
    It warm enough but not ruin it?



    The best answer I seen yet

    https://www.boards.ie/vbulletin/showpost.php?p=114953843&postcount=3311


  • #5464
    SimpleLogic
    Registered Users, Registered Users 2 Posts: 663 ✭✭✭SimpleLogic


    I'm traveling back to Ireland(Dublin) from outside of Europe in under a months time.
    It goes without saying that I'm already being careful and will be doing everything to minimize my risk on the journey back.

    I'd like to get a private Covid-19 PCR test 5 days after arrival to give me some confidence I am not infected(this is inline with recent guidelines as of yesterday https://bit.ly/3pfWvX2).

    I've done a bit of research so far and vivoclinic seems like a decent option.
    If anyone already has some experience with private testing that they could share, that would be great :)

    I'd be especially interested in how long it took to get the results. If you didn't get the PCR test and instead the LAMP(simple and quick but less accurate test) test, please specify.


  • #5465
    Be right back
    Registered Users, Registered Users 2 Posts: 6,347 ✭✭✭Be right back


    Affidea clinic is another option.


  • #5466
    Del2005
    Registered Users, Registered Users 2 Posts: 19,182 ✭✭✭✭Del2005


    Are countries outside the EU in the traffic light system? If not then having a test won't make any difference as you'll have to quarantine regardless of the result being negative for COVID.

    On the plane/boat you'll be expected to wear a mask so just buy a N95/FFP3 mask and then you won't spread or catch anything.


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  • #5467
    SimpleLogic
    Registered Users, Registered Users 2 Posts: 663 ✭✭✭SimpleLogic


    Del2005 wrote: »
    Are countries outside the EU in the traffic light system? If not then having a test won't make any difference as you'll have to quarantine regardless of the result being negative for COVID.

    On the plane/boat you'll be expected to wear a mask so just buy a N95/FFP3 mask and then you won't spread or catch anything.

    I'd be treated the same as arriving from a EU red regions.
    https://www.irishtimes.com/news/health/coronavirus/only-gold-standard-covid-test-will-result-in-restriction-free-travel-around-ireland-1.4405837

    "From midnight on November 29th, arrivals from an EU red region will also not be expected to restrict their movements as long as they have a negative Covid-19 test taken a minimum of five days after arrival in Ireland.

    The same will apply for arrivals from orange regions who did not take a pre-departure test.

    Arrivals from third countries, such as the United States, will be treated on the same basis as arrivals from red regions. Arrivals from Great Britain will be subject to the same traffic light categorisation and restrictions that apply for other EU locations."


  • #5468
    Irish Stones
    Registered Users, Registered Users 2 Posts: 2,308 ✭✭✭Irish Stones


    Sky King wrote: »
    I am no logistics expert but I think rather than trying to put together a crazy ass national logistical distribution system which could quite easily be ballsed up, they would be better off having one or two national drive through centres in a location that is capable of handling a lot of traffic - somewhere like a stadium, a racecourse or airport carpark, or the disused ferry terminal in Dun Laoghaire or similar.

    It's a LOT easier to bring a person to a vaccine than to go and create a novel, specialised cold chain to bring a vaccine to the person.


    Some minor issues have been brought up to our attention last night on TV.


    -The Pfizer vaccine is still in Phase 3 trial, it hasn't been approved yet, so we still don't know whether we have a vaccine.
    -The possible distribution won't start before the end of January 2021 with the first 50 million doses.
    -There is no scientific data available on this vaccine yet, Pfizer is to publish it within days.
    -There is no certainty that elderly people (the part of population that should receive it first) might tolerate it.
    -No data on the immunity duration.
    -It has to be stored at -80°C.
    -Once shipped from the manufacturer, the vaccine has to be administered within 5 days, or it is wasted, and this requires a very well tested chain of distribution to optimize the vaccination of tens of thousands people a day.
    -A few countries haven't the logistic to handle and distribute the vaccine according these specs.
    -EU asked member states to present a logistical and distribution plan within 2 to 3 weeks.


  • #5469
    Irish Stones
    Registered Users, Registered Users 2 Posts: 2,308 ✭✭✭Irish Stones


    hmmm wrote: »
    Italy has said they will get the Pfizer vaccine beginning January 20 2021. So not before the end of the year & they are part of the EU contract.


    Apparently Italy will also receive an extra quote of doses according to a private deal with Pfizer.


  • #5470
    Sky King
    Registered Users, Registered Users 2 Posts: 4,431 ✭✭✭Sky King


    Who was it who first mentioned about not trusting the HSE not to cock this up?

    https://independent.ie/irish-news/health/hse-wont-release-any-new-flu-vaccine-jabs-as-600000-go-missing-39732344.html


  • #5471
    is_that_so
    Registered Users, Registered Users 2 Posts: 32,136 ✭✭✭✭is_that_so


    Sky King wrote: »
    Who was it who first mentioned about not trusting the HSE not to cock this up?

    https://www.independent.ie/irish-news/health/hse-wont-release-any-new-flu-vaccine-jabs-as-600000-go-missing-39732344.html
    The HSE just distribute, they don't administer them and in the face of such an apparent shortfall in claims, it's the right thing to do.


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  • #5472
    Irish Stones
    Registered Users, Registered Users 2 Posts: 2,308 ✭✭✭Irish Stones


    Thierry12 wrote: »
    Nice Pfizer is supposedly €40 per dose, while AstraZeneca are selling to the EU for €2.50 per dose

    Last night our TV said it's €20 per dose.


  • #5473
    stephenjmcd
    Registered Users, Registered Users 2 Posts: 15,443 ✭✭✭✭stephenjmcd


    Irish Stones wrote: »
    Some minor issues have been brought up to our attention last night on TV.


    -The Pfizer vaccine is still in Phase 3 trial, it hasn't been approved yet, so we still don't know whether we have a vaccine.
    -The possible distribution won't start before the end of January 2021 with the first 50 million doses.
    -There is no scientific data available on this vaccine yet, Pfizer is to publish it within days.
    -There is no certainty that elderly people (the part of population that should receive it first) might tolerate it.
    -No data on the immunity duration.
    -It has to be stored at -80°C.
    -Once shipped from the manufacturer, the vaccine has to be administered within 5 days, or it is wasted, and this requires a very well tested chain of distribution to optimize the vaccination of tens of thousands people a day.
    -A few countries haven't the logistic to handle and distribute the vaccine according these specs.
    -EU asked member states to present a logistical and distribution plan within 2 to 3 weeks.

    None of what you've raised is any new information, most of it has been previously commented on here and the answers given and some is just completely wrong, such as administered within 5 days of being shipped thats completely false. It can be stored for 6 months at its storage temperature. 5 days in a cool box or refrigeration unit after being removed from its storage in deep chill freezers.

    Not sure what TV you watch in Italy but it ain't giving you a full picture of whats going on.


  • #5474
    Thierry12
    Closed Accounts Posts: 979 ✭✭✭Thierry12


    Hmmzis wrote: »
    Speaking of T cells, here is a vaccine candidate focusing on just that:

    https://www.medrxiv.org/content/10.1101/2020.11.04.20225417v1.full.pdf+html

    The company involved is ImmunityBio and the vaccine would appear to be nearing the end of phase1 human trials.

    The construct is a viral vector using a modified Ad5 virus. The modifications are done to prevent existing Ad5 antibodies from neutralizing the vector.
    The expressed SARS-cov-2 proteins are the standard S, an extra construct to to show more of the RBD and a few of the most prominent N (nucleocapsid) epitopes for T cell recognition. Very impressive genetic and protein engineering. Hope it works as intended.

    Commercial T Cell test should be available in few weeks

    Seems way more accurate

    97% detectable tcells vs 77% antibodies in a group of covid infected

    https://www.nytimes.com/2020/11/10/health/t-cell-test-coronavirus-immunity.html#click=https://t.co/rGeGE2FE0t


  • #5475
    stephenjmcd
    Registered Users, Registered Users 2 Posts: 15,443 ✭✭✭✭stephenjmcd


    Sky King wrote: »
    Who was it who first mentioned about not trusting the HSE not to cock this up?

    https://independent.ie/irish-news/health/hse-wont-release-any-new-flu-vaccine-jabs-as-600000-go-missing-39732344.html

    HSE completely refuting those claims this morning.


  • #5476
    Irish Stones
    Registered Users, Registered Users 2 Posts: 2,308 ✭✭✭Irish Stones


    stephenjmcd wrote: »
    It can be stored for 6 months at its storage temperature. 5 days in a cool box or refrigeration unit after being removed from its storage in deep chill freezers.


    https://www.lastampa.it/topnews/primo-piano/2020/11/11/news/le-incognite-della-distribuzione-solo-cinque-giorni-per-somministrare-le-dosi-di-vaccino-1.39524251

    A view of the article, accessible in full to subscribers only.

    That EU has asked the States to present a distribution and logistical plan within two to three weeks, and that some of them are unprepared to this, is new to me, I read it this morning.

    EDIT: Anyway, in no part of my post did I tell that these points were new information, I just listed the issues they mentioned, old or new.


  • #5477
    mandrake04
    Registered Users, Registered Users 2 Posts: 4,435 ✭✭✭mandrake04


    Irish Stones wrote: »
    Last night our TV said it's €20 per dose.

    In US $5.50

    While the overall cost of the vaccinating 95% of the population has not been quantified, $24.7 million has been spent securing 100 million needles and syringes from the US and chief political correspondent with The Conversation, Michelle Grattan, estimates it will eventually surpass ‘billions of dollars’.

    By way of comparison, AstraZeneca has already agreed to supply the US with 300 million doses of its vaccine for $1.66 billion, or around $5.50 per dose.

    Such a price would appear to be on the cheaper end of the vaccine scale, with US pharmaceutical companies such as Moderna and Pfizer hoping to generate profit with their candidates, resulting in price ranges from $54–83 per dose.

    However, the Australian Government’s COVID strategy is not restricted to one vaccine, and $256 million has been invested in the development of candidates around the world.


  • #5478
    JacksonHeightsOwn
    Registered Users, Registered Users 2 Posts: 1,913 ✭✭✭JacksonHeightsOwn


    stephenjmcd wrote: »
    HSE completely refuting those claims this morning.

    I'm anxiously awaiting the official statement from the regular know it all, "Irish stones" on this matter.


  • #5479
    funnydoggy
    Registered Users, Registered Users 2 Posts: 2,065 ✭✭✭funnydoggy


    Even reddit Ireland (who've been absolutely 100% pro lockdown & other measures without fault, even downvoting/threadbanning anyone who wasn't) are even leaning towards not taking the vaccine.

    The government and HSE need to create and share an info campaign now.


  • #5480
    Gael23
    Registered Users, Registered Users 2 Posts: 12,149 ✭✭✭✭Gael23


    if the HSE were doing their job properly they would be able to account for all vaccines distributed and identify this discrepancy


  • #5481
    Irish Stones
    Registered Users, Registered Users 2 Posts: 2,308 ✭✭✭Irish Stones


    mandrake04 wrote: »
    In US $5.50


    It's a different type of vaccine, probably the AZ doesn't need a deep cold chain, and I'm sure that the cost of this cold chain (or part of it) is included in the €20.


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  • #5482
    stephenjmcd
    Registered Users, Registered Users 2 Posts: 15,443 ✭✭✭✭stephenjmcd


    Irish Stones wrote: »
    https://www.lastampa.it/topnews/primo-piano/2020/11/11/news/le-incognite-della-distribuzione-solo-cinque-giorni-per-somministrare-le-dosi-di-vaccino-1.39524251

    A view of the article, accessible in full to subscribers only.

    That EU has asked the States to present a distribution and logistical plan within two to three weeks, and that some of them are unprepared to this, is new to me, I read it this morning.

    And ? EU asked member states weeks ago to prepare. Germany were first out of the block.

    As I said other parts of the post are just completely false but thats absolutely nothing new based on previous posts. The claim of its unusable after 5 days is not accurate.


  • #5483
    Thierry12
    Closed Accounts Posts: 979 ✭✭✭Thierry12


    funnydoggy wrote: »
    Even reddit Ireland (who've been absolutely 100% pro lockdown & other measures without fault, even downvoting/threadbanning anyone who wasn't) are even leaning towards not taking the vaccine.

    The government and HSE need to create and share an info campaign now.

    Most of those redditors are kids/young adults?

    Honestly think it will be an older person vaccine for a long time because of supply and group virus affects

    Can't see too many unders 35's getting or needing it


  • #5484
    Irish Stones
    Registered Users, Registered Users 2 Posts: 2,308 ✭✭✭Irish Stones


    stephenjmcd wrote: »
    And ? EU asked member states weeks ago to prepare. Germany were first out of the block.

    As I said other parts of the post are just completely false but thats absolutely nothing new based on previous posts. The claim of its unusable after 5 days is not accurate.


    Have you seen the title of the article that I linked?

    EDIT: How can you say that it's false when they have been explained by doctors in a public interview?


  • #5485
    funnydoggy
    Registered Users, Registered Users 2 Posts: 2,065 ✭✭✭funnydoggy


    Thierry12 wrote: »
    Most of those redditors are kids/young adults?

    Honestly think it will be an older person vaccine for a long time because of supply and group virus affects

    Can't see too many unders 35's getting or needing it




    Not all, no!

    To be fair many of my instagram followers are younger (18-24) and they're mostly leaning towards not taking it.


    Thankfully they won't be most affected if they *do* get it.


  • #5486
    mandrake04
    Registered Users, Registered Users 2 Posts: 4,435 ✭✭✭mandrake04


    Irish Stones wrote: »
    It's a different type of vaccine, probably the AZ doesn't need a deep cold chain, and I'm sure that the cost of this cold chain (or part of it) is included in the €20.

    sorry I picked you up wrong, I thought you were talking about the price of AZ.

    Yeah I suppose the Pfizer is more expensive as it requires more tricky logistics.

    US$54-$83 is closer to €45-€70 not €20


  • #5487
    stephenjmcd
    Registered Users, Registered Users 2 Posts: 15,443 ✭✭✭✭stephenjmcd


    Irish Stones wrote: »
    Have you seen the title of the article that I linked?

    EDIT: How can you say that it's false when they have been explained by doctors in a public interview?

    Yes I've read it and like most articles you've posted isn't accurate, you've quite a habit of posting unsubstantiated claims from Italian media despite it being pointed out numerous times to be false. There was also a presentation to investors which I am currently trying to find which lays it out nicely but here's the quote.

    "Once the packages are delivered, receivers can store them in ultra-low temperature freezers for up to 6 months, inside a refrigeration unit for up to 5 days, or they can refill the box with new dry ice for up to 15 days of storage." - Pfizer


  • #5488
    Thierry12
    Closed Accounts Posts: 979 ✭✭✭Thierry12


    SimpleLogic wrote: »
    I'm traveling back to Ireland(Dublin) from outside of Europe in under a months time.
    It goes without saying that I'm already being careful and will be doing everything to minimize my risk on the journey back.

    I'd like to get a private Covid-19 PCR test 5 days after arrival to give me some confidence I am not infected(this is inline with recent guidelines as of yesterday https://bit.ly/3pfWvX2).

    I've done a bit of research so far and vivoclinic seems like a decent option.
    If anyone already has some experience with private testing that they could share, that would be great :)

    I'd be especially interested in how long it took to get the results. If you didn't get the PCR test and instead the LAMP(simple and quick but less accurate test) test, please specify.

    I test all visitors with these

    https://www.hiberniamedical.ie/shop/infection-control/coronavirus/diagnostics-coronavirus/roche-sars-cov-2-rapid-antigen-test-x-25/


  • #5489
    Irish Stones
    Registered Users, Registered Users 2 Posts: 2,308 ✭✭✭Irish Stones


    stephenjmcd wrote: »
    Yes I've read it and like most articles you've posted isn't accurate, you've quite a habit of posting unsubstantiated claims from Italian media


    I will let the publishers of these Italian media that you say they are publishing rubbish, and to rely on you for their next articles. Thanks for the info.


  • #5490
    Irish Stones
    Registered Users, Registered Users 2 Posts: 2,308 ✭✭✭Irish Stones


    mandrake04 wrote: »
    sorry I picked you up wrong, I thought you were talking about the price of AZ.

    No need to be sorry.
    Yeah I suppose the Pfizer is more expensive as it requires more tricky logistics.

    US$54-$83 is closer to €45-€70 not €20

    €20 is what I knew from our TV last night, but as stephenjmcd says, our media only give us Italian false and rubbish news.


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  • #5491
    dominatinMC
    Registered Users, Registered Users 2 Posts: 3,130 ✭✭✭dominatinMC


    funnydoggy wrote: »
    Not all, no!

    To be fair many of my instagram followers are younger (18-24) and they're mostly leaning towards not taking it.


    Thankfully they won't be most affected if they *do* get it.
    Tbh, I wouldn't worry about that. Just convince (if that's even needed) a few cash-strapped "influencers" to take the vaccine and the distracted multitude will follow.


This discussion has been closed.
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