Beanybabog wrote: » Why does the Pfizer vaccine need to be so cold? I’ve read numerous articles explaining the logistical challenges but not why it needs to be so cold. I read one that suggested the freezers can only be opened for a short amount of time... surely when you’re going to be injected the vaccine can’t be -80 (does it freeze?) so how do they manage to make It warm enough but not ruin it?
Del2005 wrote: » Are countries outside the EU in the traffic light system? If not then having a test won't make any difference as you'll have to quarantine regardless of the result being negative for COVID. On the plane/boat you'll be expected to wear a mask so just buy a N95/FFP3 mask and then you won't spread or catch anything.
Sky King wrote: » I am no logistics expert but I think rather than trying to put together a crazy ass national logistical distribution system which could quite easily be ballsed up, they would be better off having one or two national drive through centres in a location that is capable of handling a lot of traffic - somewhere like a stadium, a racecourse or airport carpark, or the disused ferry terminal in Dun Laoghaire or similar. It's a LOT easier to bring a person to a vaccine than to go and create a novel, specialised cold chain to bring a vaccine to the person.
hmmm wrote: » Italy has said they will get the Pfizer vaccine beginning January 20 2021. So not before the end of the year & they are part of the EU contract.
Sky King wrote: » Who was it who first mentioned about not trusting the HSE not to cock this up?https://www.independent.ie/irish-news/health/hse-wont-release-any-new-flu-vaccine-jabs-as-600000-go-missing-39732344.html
Thierry12 wrote: » Nice Pfizer is supposedly €40 per dose, while AstraZeneca are selling to the EU for €2.50 per dose
Irish Stones wrote: » Some minor issues have been brought up to our attention last night on TV. -The Pfizer vaccine is still in Phase 3 trial, it hasn't been approved yet, so we still don't know whether we have a vaccine. -The possible distribution won't start before the end of January 2021 with the first 50 million doses. -There is no scientific data available on this vaccine yet, Pfizer is to publish it within days. -There is no certainty that elderly people (the part of population that should receive it first) might tolerate it. -No data on the immunity duration. -It has to be stored at -80°C. -Once shipped from the manufacturer, the vaccine has to be administered within 5 days, or it is wasted, and this requires a very well tested chain of distribution to optimize the vaccination of tens of thousands people a day. -A few countries haven't the logistic to handle and distribute the vaccine according these specs. -EU asked member states to present a logistical and distribution plan within 2 to 3 weeks.
Hmmzis wrote: » Speaking of T cells, here is a vaccine candidate focusing on just that:https://www.medrxiv.org/content/10.1101/2020.11.04.20225417v1.full.pdf+html The company involved is ImmunityBio and the vaccine would appear to be nearing the end of phase1 human trials. The construct is a viral vector using a modified Ad5 virus. The modifications are done to prevent existing Ad5 antibodies from neutralizing the vector. The expressed SARS-cov-2 proteins are the standard S, an extra construct to to show more of the RBD and a few of the most prominent N (nucleocapsid) epitopes for T cell recognition. Very impressive genetic and protein engineering. Hope it works as intended.
Sky King wrote: » Who was it who first mentioned about not trusting the HSE not to cock this up?https://independent.ie/irish-news/health/hse-wont-release-any-new-flu-vaccine-jabs-as-600000-go-missing-39732344.html
stephenjmcd wrote: » It can be stored for 6 months at its storage temperature. 5 days in a cool box or refrigeration unit after being removed from its storage in deep chill freezers.
Irish Stones wrote: » Last night our TV said it's €20 per dose.
While the overall cost of the vaccinating 95% of the population has not been quantified, $24.7 million has been spent securing 100 million needles and syringes from the US and chief political correspondent with The Conversation, Michelle Grattan, estimates it will eventually surpass ‘billions of dollars’. By way of comparison, AstraZeneca has already agreed to supply the US with 300 million doses of its vaccine for $1.66 billion, or around $5.50 per dose. Such a price would appear to be on the cheaper end of the vaccine scale, with US pharmaceutical companies such as Moderna and Pfizer hoping to generate profit with their candidates, resulting in price ranges from $54–83 per dose. However, the Australian Government’s COVID strategy is not restricted to one vaccine, and $256 million has been invested in the development of candidates around the world.
stephenjmcd wrote: » HSE completely refuting those claims this morning.
mandrake04 wrote: » In US $5.50
Irish Stones wrote: » https://www.lastampa.it/topnews/primo-piano/2020/11/11/news/le-incognite-della-distribuzione-solo-cinque-giorni-per-somministrare-le-dosi-di-vaccino-1.39524251 A view of the article, accessible in full to subscribers only. That EU has asked the States to present a distribution and logistical plan within two to three weeks, and that some of them are unprepared to this, is new to me, I read it this morning.
funnydoggy wrote: » Even reddit Ireland (who've been absolutely 100% pro lockdown & other measures without fault, even downvoting/threadbanning anyone who wasn't) are even leaning towards not taking the vaccine. The government and HSE need to create and share an info campaign now.
stephenjmcd wrote: » And ? EU asked member states weeks ago to prepare. Germany were first out of the block. As I said other parts of the post are just completely false but thats absolutely nothing new based on previous posts. The claim of its unusable after 5 days is not accurate.
Thierry12 wrote: » Most of those redditors are kids/young adults? Honestly think it will be an older person vaccine for a long time because of supply and group virus affects Can't see too many unders 35's getting or needing it
Irish Stones wrote: » It's a different type of vaccine, probably the AZ doesn't need a deep cold chain, and I'm sure that the cost of this cold chain (or part of it) is included in the €20.
Irish Stones wrote: » Have you seen the title of the article that I linked? EDIT: How can you say that it's false when they have been explained by doctors in a public interview?
SimpleLogic wrote: » I'm traveling back to Ireland(Dublin) from outside of Europe in under a months time. It goes without saying that I'm already being careful and will be doing everything to minimize my risk on the journey back. I'd like to get a private Covid-19 PCR test 5 days after arrival to give me some confidence I am not infected(this is inline with recent guidelines as of yesterday https://bit.ly/3pfWvX2). I've done a bit of research so far and vivoclinic seems like a decent option. If anyone already has some experience with private testing that they could share, that would be great I'd be especially interested in how long it took to get the results. If you didn't get the PCR test and instead the LAMP(simple and quick but less accurate test) test, please specify.
stephenjmcd wrote: » Yes I've read it and like most articles you've posted isn't accurate, you've quite a habit of posting unsubstantiated claims from Italian media
mandrake04 wrote: » sorry I picked you up wrong, I thought you were talking about the price of AZ.
Yeah I suppose the Pfizer is more expensive as it requires more tricky logistics. US$54-$83 is closer to €45-€70 not €20
funnydoggy wrote: » Not all, no! To be fair many of my instagram followers are younger (18-24) and they're mostly leaning towards not taking it. Thankfully they won't be most affected if they *do* get it.
Irish Stones wrote: » I will let the publishers of these Italian media that you say they are publishing rubbish, and to rely on you for their next articles. Thanks for the info.
