COVID-19: Vaccine/antidote and testing procedures Megathread [Mod Warning - Post #1]

stockshares · 05-10-2020 05:54PM

https://twitter.com/CNN/status/1313158828184293377?s=19

Marhay70 · 05-10-2020 06:17PM

stockshares wrote: »

https://twitter.com/CNN/status/1313158828184293377?s=19

Really don't know what to think about Trump's "illness" On one hand I consider him capable of the most underhand deeds imaginable, on the other, could he really manage to pull the wool over all the hospital staff who must have been involved? Could you really trust them all to keep it secret in the face of the press offering big bucks to tell all?

scouserstation · 05-10-2020 06:42PM

There seems to be growng evidence of the role that Vitamin D can play in the prevention and even treatment of Covid 19 with studies showing a reduction in ICU admissions as well as preventing people from getting infected in the first place, so is it time we start seriously looking at Vitamin D?

https://www.irishtimes.com/news/health/vitamin-d-deficit-link-to-covid-19-severity-considerable-1.4371795

charlie14 · 05-10-2020 06:55PM

Marhay70 wrote: »

Really don't know what to think about Trump's "illness" On one hand I consider him capable of the most underhand deeds imaginable, on the other, could he really manage to pull the wool over all the hospital staff who must have been involved? Could you really trust them all to keep it secret in the face of the press offering big bucks to tell all?

Are the hospital staff treating him civilian or military

charlie14 · 05-10-2020 06:58PM

scouserstation wrote: »

There seems to be growng evidence of the role that Vitamin D can play in the prevention and even treatment of Covid 19 with studies showing a reduction in ICU admissions as well as preventing people from getting infected in the first place, so is it time we start seriously looking at Vitamin D?

https://www.irishtimes.com/news/health/vitamin-d-deficit-link-to-covid-19-severity-considerable-1.4371795

Not exactly up to the minute reporting from the Irish Times.

That has been around for months.

ShineOn7 · 05-10-2020 08:08PM

I'm reading on Reddit that convalescent plasma is saving lives in the States

Are we using it here yet?

Marhay70 · 05-10-2020 08:14PM

charlie14 wrote: »

Are the hospital staff treating him civilian or military

Actually, given his latest statement I'm coming down on the side of a major fraud being perpetrated. As usual he can't quit when he's ahead.

CIARAN_BOYLE · 05-10-2020 08:27PM

ShineOn7 wrote: »

I'm reading on Reddit that convalescent plasma is saving lives in the States

Are we using it here yet?

We've been involved in trials of Convalescent plasma since April.

Not enough evidence has been gathered to approve it as a treatment. What evidence that has been gathered is considered of a low quality by the who.

The blood transfusion service has a system to label blood donations received as convalescent plasma when appropriate.

charlie14 · 05-10-2020 08:38PM

Marhay70 wrote: »

Actually, given his latest statement I'm coming down on the side of a major fraud being perpetrated. As usual he can't quit when he's ahead.

If it is then it has backfired. From Opinion polls the majority of Americans think he has only himself to blame.

plodder · 05-10-2020 09:17PM

Marhay70 wrote: »

Really don't know what to think about Trump's "illness" On one hand I consider him capable of the most underhand deeds imaginable, on the other, could he really manage to pull the wool over all the hospital staff who must have been involved? Could you really trust them all to keep it secret in the face of the press offering big bucks to tell all?

I watched the news conference this evening and my guess is he definitely has it, but has had mild symptoms (so far).

Whatever about some of the drugs he's getting, the Regeneron cocktail is being trialed in different settings including as a preventive treatment. So, it doesn't look far fetched that he would be getting these drugs on the same basis, ie to prevent a mild infection from worsening.

The medics as good as admitted though that he could be back in hospital any time over the next seven days if his condition worsens suddenly.

Marhay70 · 05-10-2020 09:44PM

plodder wrote: »

I watched the news conference this evening and my guess is he definitely has it, but has had mild symptoms (so far).

Whatever about some of the drugs he's getting, the Regeneron cocktail is being trialed in different settings including as a preventive treatment. So, it doesn't look far fetched that he would be getting these drugs on the same basis, ie to prevent a mild infection from worsening.

The medics as good as admitted though that he could be back in hospital any time over the next seven days if his condition worsens suddenly.

This is what the great man had to say tonight

"I will be leaving the great Walter Reed Medical Center today at 6:30 P.M. Feeling really good! Don’t be afraid of Covid. Don’t let it dominate your life. We have developed, under the Trump Administration, some really great drugs & knowledge. I feel better than I did 20 years ago!"

Obviously knows more than we do and more than most of the doctors in his own country.

Hmmzis · 05-10-2020 10:28PM

Marhay70 wrote: »

"... I feel better than I did 20 years ago!"

They gave him dexamethsone, it's a glucocorticoid. From personal experience I can say it makes one real happy and feeling like moving mountains.

Gael23 · 06-10-2020 04:39AM

I has an allergic reaction to an antibiotic in February just as Covid 19 was kicking off and my GP thought about giving me dexamethsone

plodder · 06-10-2020 07:21AM

Hmmzis wrote: »

They gave him dexamethsone, it's a glucocorticoid. From personal experience I can say it makes one real happy and feeling like moving mountains.

Yes, that was the steroids talking. And telling people not to worry about Covid, when he got a drug regimen that isn't available to anyone else, and possibly has never been given to anyone else.

Hmmzis · 06-10-2020 11:15AM

Pfizer/BioNTech also starting a rolling review process with EMA for their vaccine candidate:

https://investors.biontech.de/news-releases/news-release-details/biontech-and-pfizer-initiate-rolling-submission-european

Same process as AZ/Oxford initiated last week.

hmmm · 06-10-2020 03:13PM

Interesting bit of vaccine politics going on.

The FDA published draft new guidelines for its vaccine advisory committee on emergency use authorisations for vaccines which would have meant nothing was likely to get approved before the election. The White House over-ruled them.
https://www.usnews.com/news/health-news/articles/2020-10-05/white-house-nixes-tougher-fda-guidelines-on-vaccine-approval

The FDA have gone and published the new guidelines anyway:
https://twitter.com/gregggonsalves/status/1313477606067572742

eigrod · 06-10-2020 03:20PM

https://twitter.com/rtenews/status/1313482038247395328?s=21

ACitizenErased · 06-10-2020 03:26PM

That's a big statement from Tedros. Very big.

hmmm · 06-10-2020 03:28PM

ACitizenErased wrote: »

That's a big statement from Tedros. Very big.

He could be talking about the Chinese vaccines. We sometimes see things through Western eyes, when the WHO are in many ways more focused on the poorer countries.

Gael23 · 06-10-2020 03:29PM

Is there no hope of Oxford being ready this year?

Santy2015 · 06-10-2020 03:29PM

hmmm wrote: »

He could be talking about the Chinese vaccines. We sometimes see things through Western eyes, when the WHO are in many ways more focused on the poorer countries.

I’d doubt that though surely?

Pfizer and Oxford are close...

hmmm · 06-10-2020 03:32PM

Santy2015 wrote: »

I’d doubt that though surely?

Pfizer and Oxford are close...

The Pfizer/Moderna vaccines are unlikely to be of much interest to poorer countries - particularly with the storage requirements.

The Chinese have been making good progress and are promising to make their vaccines available cheaply to some countries:
https://www.reuters.com/article/us-health-coronavirus-who-china-idUSKBN26R19B

"China is in talks to have its locally-produced COVID-19 vaccines assessed by the World Health Organization, as a step toward making them available for international use, a WHO official said on Tuesday."

is_that_so · 06-10-2020 05:15PM

UK study to look at the effect of the immune system on COVID.

British scientists have launched a major study aimed at uncovering the critical role that human antibodies and other immune defences play in the severity of Covid-19 cases.

https://www.theguardian.com/science/2020/oct/04/scientists-study-whether-immune-response-wards-off-or-worsens-covid

Gael23 · 06-10-2020 07:18PM

It appears the Oxford challenge trials are not to begin until January which is disappointing. I understood we would be looking at getting approval from regulators around then
https://www.telegraph.co.uk/global-health/science-and-disease/covid-19-vaccine-coronavirus-update-latest-ready-trial-news/

ShineOn7 · 06-10-2020 08:17PM

hmmm wrote: »

He could be talking about the Chinese vaccines. We sometimes see things through Western eyes, when the WHO are in many ways the mouthpiece of China since this began.

FYP

Sweet.Science · 07-10-2020 07:45AM

Gael23 wrote: »

It appears the Oxford challenge trials are not to begin until January which is disappointing. I understood we would be looking at getting approval from regulators around then
https://www.telegraph.co.uk/global-health/science-and-disease/covid-19-vaccine-coronavirus-update-latest-ready-trial-news/

Not exactly true . These challenge trials will most likely occur after intitial distribution of the vaccine

is_that_so · 07-10-2020 09:11AM

This could be upsetting for the just a flu' proponents - a study on the age profile of COVID patients.

Patients hospitalized with COVID-19 were more likely male, younger, and, in both the US and Spain, had fewer comorbidities and lower medication use than hospitalized influenza patients according to a recent study published by the Observational Health Data Sciences and Informatics (OHDSI) community

https://www.sciencedaily.com/releases/2020/10/201006153512.htm

funnydoggy · 07-10-2020 12:32PM

(Boston) – Being previously infected with a coronaviruses that cause the “common cold” may decrease the severity of severe acute respiratory syndrome coronavirus (SARS-CoV-2) infections, according to results of a new study. Led by researchers at Boston Medical Center and Boston University School of Medicine, the study also demonstrates that the immunity built up from previous non-SARS-CoV-2 coronavirus infections does not prevent individuals from getting COVID-19. Published in the Journal of Clinical Investigation, the findings provide important insight into the immune response against SARS-CoV-2, which could have significant implications on COVID-19 vaccine development.

Something similar was posted here recently. Here's a press piece on it -

https://www.bmc.org/news/press-releases/2020/10/06/previous-infection-other-types-coronaviruses-may-lessen-severity

MerlinSouthDub · 07-10-2020 06:47PM

Eli Lilly seeking approval for their Covid treatment.

https://www.irishtimes.com/business/health-pharma/lilly-seeks-emergency-approval-for-covid-drug-1.4374730?mode=amp

Good news, albeit only limited quantities will be available

Sweet.Science · 08-10-2020 09:58AM

A lot of talk that these vaccines will be rolled out pretty soon. Once approved really. Which should be by November

COVID-19: Vaccine/antidote and testing procedures Megathread [Mod Warning - Post #1]

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