Covid 19 Part XXIII-33,444 in ROI(1,792 deaths) 9,541 in NI(577 deaths)(22/09)Read OP

ACitizenErased · 21-09-2020 08:21PM

Further observations from the t-cell paper published in Cell medical journal:

Of note, we detected cross-reactive T cell responses against spike or membrane in 28% of the unexposed healthy blood donors, consistent with a high degree of pre-existing immune responses potentially induced by other coronaviruses (Braun et al., 2020; Grifoni et al., 2020; Le Bert et al., 2020).

The fact that memory B cells (Juno et al., 2020) and robust T cell memory is formed after SARS-CoV-2 infection, suggests that potent adaptive immunity is maintained to provide protection against severe re-infection. In line with these observations, none of the convalescent individuals in this study, including those with previous mild disease, have experienced further episodes of COVID-19.

Collectively, our data provide a functional and phenotypic map of SARS-CoV-2-specific T cell immunity across the full spectrum of exposure, infection, and disease. The observation that many individuals with asymptomatic or mild COVID-19, after SARS-CoV-2 exposure or infection, generated highly durable and functionally replete memory T cell responses, not uncommonly in the absence of detectable humoral responses, further suggests that natural exposure or infection could prevent recurrent episodes of severe COVID-19.

Micky 32 · 21-09-2020 08:22PM

Polar101 wrote: »

It's absolutely bizarre.

For me the most fascinating thing is how people still think they can win arguments on the internet (possibly by posting as many links they can google).

Are you talking about the positive links or the negative ones?

owlbethere · 21-09-2020 08:23PM

caveat emptor wrote: »

Please don't tell lies in support of your opinion. Coronavirus' don't confer longterm immunity. Why would this one be different? If we can get infected on a biannual basis this will be never ending. People need to start confronting reality.

I remember people back in Feb saying nothing to worry about it's only an outbreak in China.
I remember people saying masks don't work.
I remember people saying it wasn't airborne.
I remember people saying there wouldn't be another wave.

All examples of wishful thinking.

Some people just don't get stuff. Then they get angry and take it out on anyone that'll listen. Sometimes it ends with hitting someone over the head with a two by four wrapped in a flag. Doesn't change the situation one iota though.

https://twitter.com/EricTopol/status/1305605844013203456?s=20

I remember someone who's a nobel prize winner coming out and saying the virus is going to be gone by June and so many people here posted it here and put faith in the article. So many people clutching them straws putting so much faith in what your man said that the virus was going to die down and be gone. That was nonsense and wishful thinking.

bb1234567 · 21-09-2020 08:23PM

Excess deaths in Peru rise to almost 70,000 as of late August- representing an absolutely staggering 0.21% of the country's population.

About half of these are confirmed as COVID deaths, and with serum studies estimating that 25% of Peruvian having had COVID and depending on how many more of the excess deaths are unconfirmed COVID deaths this means the IFR in the region of 0.4%-0.85%. As has been widely theorised for months now

https://www.reuters.com/article/us-health-coronavirus-peru-vaccine-idUSKBN25O2CS

ACitizenErased · 21-09-2020 08:24PM

Micky 32 wrote: »

Are you talking about the positive links or the negative ones?

Mad how people believe Twitter trumps medical journals

eagle eye · 21-09-2020 08:24PM

ACitizenErased wrote:

Anyone advocating for 'virtual classrooms' clearly has absolutely no idea how difficult online learning is. Ridiculous suggestion.

My young man is being homeschooled at the minute. I've no issue with virtual classrooms though and it's not very difficult at all.
A lot of people just like to put roadblocks in the way of good sense.

When a couple of kids die from the virus the schools will be shut again.
We shouldn't be waiting for that to happen.

growleaves · 21-09-2020 08:26PM

Micky 32 wrote: »

Are you talking about the positive links or the negative ones?

I think he's talking about all of it.

I count only two posters in the entire forum who have changed their minds, and one of those became more sceptical of restrictions because of the behaviour of the government (i.e. not because of anything posted here).

This is like one of those "glass bead games" from the Hesse novel.

Polar101 · 21-09-2020 08:27PM

I saw this somewhere else, so I wouldn't know how reliable it is. But it's a study done in the US (almost 200,000 patients too) regarding Vitamin D and Covid, and seems to suggest lower positivity rates in people with higher Vitamin D levels.

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0239252

the association between lower SARS-CoV-2 positivity rates and higher circulating 25(OH)D levels remained significant

Gael23 · 21-09-2020 08:29PM

Any updates on the outbreak involving Wilton shopping centre?

caveat emptor · 21-09-2020 08:29PM

ACitizenErased wrote: »

I'm not sure if you understand immunity?
1) Antibodies are not permanent.
2) There's no such thing as complete sterilising natural immunity.
3) In line with these observations, none of the convalescent individuals in this study, including those with previous mild disease, have experienced further episodes of COVID-19. (I can put things in bold too)

Your bold quote is missing something. I'll help you out.

"Yet"

In line with these observations, none of the convalescent individuals in this study, including those with previous mild disease, have experienced further episodes of COVID-19 Yet.

Martina1991 · 21-09-2020 08:29PM

Strawberry Milkshake wrote: »

Think it’s letterkenny and Milford that are getting the most. Carrick has majority of Leitrim's numbers.

Deleted User wrote: »

Donegal has a very big influx of people from northern Ireland especially and other parts of the country during the summer months. The beaches are majority northern reg cars.

There was an outbreak in a Mexican restaurant in Letterkenny with 9 staff infected and they've had ~15-20 cases every day since.

If it was Northerners or tourists causing infections I would have thought cases would have increased in seaside towns instead of Letterkenny, but it hasn't.

I think that restaurant is the epicentre for all these recent cases.

ACitizenErased · 21-09-2020 08:30PM

Polar101 wrote: »

I saw this somewhere else, so I wouldn't know how reliable it is. But it's a study done in the US (almost 200,000 patients too) regarding Vitamin D and Covid, and seems to suggest lower positivity rates in people with higher Vitamin D levels.

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0239252

I've been taking vit d since March. Haven't been infected

ACitizenErased · 21-09-2020 08:31PM

caveat emptor wrote: »

Your bold quote is missing something. I'll help you out.

"Yet"

In line with these observations, none of the convalescent individuals in this study, including those with previous mild disease, have experienced further episodes of COVID-19 Yet.

You can't add words to studies. What sort of nonsense is that? You're joking at this stage, surely? This has to be a wind up.

In line with these observations, none of the convalescent individuals in this study, including those with previous mild disease, have experienced further episodes of COVID-19. Of note, we detected cross-reactive T cell responses against spike or membrane in 28% of the unexposed healthy blood donors, consistent with a high degree of pre-existing immune responses potentially induced by other coronaviruses (Braun et al., 2020; Grifoni et al., 2020; Le Bert et al., 2020).

edit: oh by the way, the study involved people infected in February/March, so it's been a while.

caveat emptor · 21-09-2020 08:33PM

ACitizenErased wrote: »

Also are you going to provide a source from a medical journal on the graph and whatever you quoted? Because it's not from the paper I posted.

Ah so you didn't read the paper in the tweet about the coronavirus reinfections.
Good to know.
I'll help you out some more.
It's a great journal.

https://www.nature.com/articles/s41591-020-1083-1

ACitizenErased · 21-09-2020 08:34PM

caveat emptor wrote: »

Ah so you didn't read the paper in the tweet about the coronavirus reinfections.
Good to know.
I'll help you out some more.
It's a great journal.

https://www.nature.com/articles/s41591-020-1083-1

That isn't even about COVID... dear god.
HCoV-NL63, HCoV-229E, HCoV-OC43 and HCoV-HKU1 =/= SARS-COVI-2.......

SeaBreezes · 21-09-2020 08:37PM

ACitizenErased wrote: »

Further observations from the t-cell paper published in Cell medical journal:

Ive been following this Dr. On twitter, phd in Tcell immunology. But he seems very wary of Tcell immunity. I dont understand it fully, as a lot of it is over my head.

But from what i THINK i understand, hes wary because the sarscov2 virus ages Tcells and kills them. So after an infection, we have less and it takes time for the body to reproduce (months) which leaves our bodies open to all sorts of other issues (cancer, epv, herpes, other sickness) and if we get a second dose of the virus, well its very dodgy.

Anyway, for anyone interested:
https://twitter.com/fitterhappierAJ/status/1308051767981150208?s=19

Goldrickssan · 21-09-2020 08:38PM

ACitizenErased wrote: »

That isn't even about COVID... dear god.
HCoV-NL63, HCoV-229E, HCoV-OC43 and HCoV-HKU1 =/= SARS-COVI-2.......

Did you not hear???
Covid 19 is the seasonal flu now

ACitizenErased · 21-09-2020 08:38PM

Just a heads up RE: coronaviruses.
They're not all the same.
SARS and MERS produced long term immunity. Antibodies are still detected.
Other coronaviruses are not the same.
You can't really make an assumption that every single coronavirus has the same immunity.

ACitizenErased · 21-09-2020 08:38PM

Goldrickssan wrote: »

Did you not hear???
Covid 19 is the seasonal flu now

They literally are the seasonal coronavirus strains

caveat emptor · 21-09-2020 08:44PM

ACitizenErased wrote: »

Just a heads up RE: coronaviruses.
They're not all the same.
SARS and MERS produced long term immunity. Antibodies are still detected.
Other coronaviruses are not the same.
You can't really make an assumption that every single coronavirus has the same immunity.

The viruses were contained so there was chance to observe reinfection cycle. They also produced long term damage and death.

Those other coronavirus' are the only ones to go off.

Look believe what you want, couldn't give a **** what you think.
Not bothered, just find it funny that you attempt to **** on the credibility of a twitter link but fail to see it contains a link to a study in one of the most respected scientific journals in the world. :pac:

lukas8888 · 21-09-2020 08:45PM

Strawberry Milkshake wrote: »

Think it’s letterkenny and Milford that are getting the most. Carrick has majority of Leitrim's numbers.

Leitrim features on the bad list,up to Saturday it had 23 cases for the previous 14 day's.Because of it's tiny population that equates to almost 70 per 100,000 even though it recorded less than 2 cases each day.

Funsterdelux · 21-09-2020 08:54PM

Plumbthedepths wrote: »

CDC rowing back on..https://www.cnbc.com/2020/09/21/cdc-says-it-erroneously-posted-guidance-that-said-coronavirus-spreads-through-air-and-and-travel-beyond-six-feet.html

Thats quite an "error" to make.

Plumbthedepths · 21-09-2020 09:02PM

eagle eye wrote: »

My young man is being homeschooled at the minute. I've no issue with virtual classrooms though and it's not very difficult at all.
A lot of people just like to put roadblocks in the way of good sense.

When a couple of kids die from the virus the schools will be shut again.
We shouldn't be waiting for that to happen.

Poor internet access and no broadband are pretty substantial 'roadblocks' for a virtual classroom.
As for good sense, that's your opinion. Keeping your son locked away from social interaction with other kids is not a good thing btw.

bb1234567 · 21-09-2020 09:02PM

Will be well over a hundred in hospital in about a day or two now, around a fifth of our peak, but without most of the same kerfuffle. About 475 in hospital nationwide during the April peak iirc?

Deeper Blue · 21-09-2020 09:05PM

bb1234567 wrote: »

Will be well over a hundred in hospital in about a day or two now, around a fifth of our peak, but without most of the same kerfuffle. About 475 in hospital nationwide during the April peak iirc?

I believe it was circa 860 at the peak with 160 in ICU

Funsterdelux · 21-09-2020 09:07PM

growleaves wrote: »

A few months ago posters were warning about a possible repeat of the second wave of the Spanish flu,which killed somewhere between 50 to 100 million people.

Now its like "I told you there'd be a second wave" (!)

Fair play for having the balls to gloat over predicting a deadly second wave, when that second wave kills roughly zero people a day in this country most days. A bit of step down from the Spanish flu stuff.

Come on name names, or I should say posters.

Name and shame

Happy4all · 21-09-2020 09:08PM

very few ICUs beds available. Will they stop treating the cancer patients again

MerlinSouthDub · 21-09-2020 09:11PM

eagle eye wrote: »

My young man is being homeschooled at the minute. I've no issue with virtual classrooms though and it's not very difficult at all.
A lot of people just like to put roadblocks in the way of good sense.

When a couple of kids die from the virus the schools will be shut again.
We shouldn't be waiting for that to happen.

Do you work full time?

Flu is more dangerous to children than COVID-19. Should schools close every winter due to a flu outbreak?

iamwhoiam · 21-09-2020 09:12PM

eagle eye wrote: »

My young man is being homeschooled at the minute. I've no issue with virtual classrooms though and it's not very difficult at all.
A lot of people just like to put roadblocks in the way of good sense.

When a couple of kids die from the virus the schools will be shut again.
We shouldn't be waiting for that to happen.

It may not be difficult for you but their are thousands of kids who would be at a huge disadvantage if they couldn’t go to school
Kids from abusive or neglecful homes
Children in a family with a child with special needs , children with special needs , children with autism who will regress without the input of professionals and the interaction with other kids
We must all remember that not everyone is as lucky as we are

wowzer · 21-09-2020 09:12PM

Funsterdelux wrote: »

Come on name names, or I should say posters.

Name and shame

Don't you know names arent usually named in here, usually hide behind cowardly statements like "some people here" or "certain posters" . It is all designed to stir the you know what.

Covid 19 Part XXIII-33,444 in ROI(1,792 deaths) 9,541 in NI(577 deaths)(22/09)Read OP

Comments