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Covid19 Part XV - 15,251 in ROI (610 deaths) 2,645 in NI (194 deaths) (19/04) Read OP

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Comments

  • #4232
    ihdxwz4a3pem9j
    Closed Accounts Posts: 82 ✭✭ihdxwz4a3pem9j


    DevilsHaircut wrote: »
    What are your thoughts on convalescent plasma/antibody therapy as a potentially quick route to treating the sickest patients? It seems that we're being a bit slow to join the other countries starting/investigating it.

    https://ec.europa.eu/health/blood_tissues_organs/covid-19_en

    The FDA is a board that reviews a medical treatment, and determines if it is safe for administration. They have determined that the evidence for the plasma is equivocal. Hence, they have yet to approve its use in patients. We will have to do proper clinical trials in patients before we know for sure its role. It is only an experimental treatment. A clinical trial has various steps: pre-clinical (you look at a medical therapy in animals, and determine it safe and effective). Phase I (you give it to healthy volunteers- you don’t want to test an experimental therapy on the sickest patients, their bodies are already compromised). Phase 2 (you want to test it on a small group of patients with the disease, to see if it’s effective and safe). Phase 3 (you want to test it on a large group of patients to see if it is effective and safe). We will have to get the plasma through these trials, before we know a) if it is actually effective and b) if it safe. I know that people might feel, sure what have we to lose. But until we know it’s effective and safe, we should not roll out to people.


  • #4233
    smelly sock
    Closed Accounts Posts: 6,820 ✭✭✭smelly sock


    Alisa Odd Wasp wrote: »
    I am also a frontline doctor. I think that we are doing a terrific job! I am very proud to be working for the HSE! I have no gripes against the system, nor have I seen anything that was terrible. I do not have any political affiliation. I am simply stating what I see. All levels of the HSE are producing one hell of a response against this virus. Stay safe everybody!

    Thank you so much . We owe our liberty to you guys and our futures are in your hands.

    I wish you the best.

    Please stay strong so we can see years more of sunrises amd sunsets.


  • #4234
    Daroxtar
    Registered Users, Registered Users 2 Posts: 4,499 ✭✭✭Daroxtar


    Beechwoodspark wrote: »
    Well yeah it is until maybe June July time but The bigger story could be the recovery in second part of the year I choose to be optimistic.

    So when is Love Island back?


  • #4235
    Be right back
    Registered Users, Registered Users 2, Paid Member Posts: 6,479 ✭✭✭Be right back


    Alisa Odd Wasp wrote: »
    I am also a frontline doctor. I think that we are doing a terrific job! I am very proud to be working for the HSE! I have no gripes against the system, nor have I seen anything that was terrible. I do not have any political affiliation. I am simply stating what I see. All levels of the HSE are producing one hell of a response against this virus. Stay safe everybody!

    Thank you and all of your colleagues.


  • #4236
    peasant
    Registered Users, Registered Users 2 Posts: 17,789 ✭✭✭✭peasant


    And now for something completely different.

    Playmobil have started producing face masks, available in their online shop

    509616.JPG


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  • #4237
    ShineOn7
    Closed Accounts Posts: 4,550 ✭✭✭ShineOn7


    Rob A. Bank wrote: »
    17th in the world for deaths = 406 very unfortunate people RIP
    20th in the world for cases = 11,479 unfortunate people
    124th in the world for population = 4,937,786 people
    18th in the world for testing = 18,358/million pop (top 10 for testing if micro states are excluded)


    Are those figures all per head of population?


  • #4238
    Kermit.de.frog
    Registered Users, Registered Users 2 Posts: 25,811 ✭✭✭✭Kermit.de.frog


    https://www.theguardian.com/world/live/2020/apr/14/coronavirus-live-news-cases-worldwide-near-2-million-trump-repeats-who-funding-threat-latest-updates
    In Germany, local media are reporting that zoos are making contingency plans, including killing some of the animals, should the lockdown continue without a solution to their financial troubles.

    Neumünster Zoo’s director has told Die Welt they have “listed the animals we will have to slaughter first” and said some may even have to be fed to others. But even such drastic plans would not be sufficient to solve the problem.

    Verena Kaspari told the paper the step would be a last resort and “unpleasant”. She referred to the plight of the piscivorous animals and added: “If it comes to it, I’ll have to euthanise animals, rather than let them starve.”

    :(


  • #4239
    Beechwoodspark
    Registered Users, Registered Users 2 Posts: 16,179 ✭✭✭✭Beechwoodspark


    Yes agreed it has been a bad year for news.

    One tiny tiny positive in all this is that air quality has improved with lower co2 emissions. That is one thing in all this I would keep.

    But yeah, other than that I am clutching at straws.


  • #4240
    ShineOn7
    Closed Accounts Posts: 4,550 ✭✭✭ShineOn7


    Iamabeliever wrote: »
    It's too soon to be sure


    A much needed laugh

    And I read it in a dry Culchie's accent for some reason


  • #4241
    [Deleted User]
    Posts: 6,583 ✭✭✭ [Deleted User]


    Daroxtar wrote: »
    So when is Love Island back?

    Hopefully never


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  • #4242
    Rob A. Bank
    Registered Users, Registered Users 2 Posts: 1,842 ✭✭✭Rob A. Bank


    joe_99 wrote: »
    Worldometer are just collating propaganda from countries. The Irish numbers are wrong we all know that as the modellers themselves have indicated thus in the daily press conferences.

    We can also then say that the numbers are wrong in every other country on the planet. No country has tested everyone with it, many are dying untested etc.

    Now that we have established all numbers are wrong what is the point of comparison?

    The only figure we can rely on is ICU numbers. Ultimately this is the fundamental measure of our success or failure.

    The ICU numbers are totally dependent on the triage metrics applied in deciding who is being admitted there.


  • #4243
    tobefrank321
    Registered Users, Registered Users 2 Posts: 4,621 ✭✭✭tobefrank321


    Gael23 wrote: »
    The restrictions are clearly not working

    They aren't working in the east/Dublin region where a high proportion of deaths are. But it seems like its more nursing homes where its not working.


  • #4244
    SEPT 23 1989
    Registered Users, Registered Users 2 Posts: 43,038 ✭✭✭✭SEPT 23 1989


    Vivienne23 wrote: »

    Many small businesses will close they were just getting over the last recession and this year was going to be the money year where they might make a few bob , they won’t bother reopening cos it’s just not worth the hassle anymore

    Many of the small businesses who traded through the last recession will have very little debt today unlike 2008

    No way in hell they will do another one

    Too many mental scars from the last time

    They can walk way today clean and take the dole


  • #4245
    10000maniacs
    Registered Users, Registered Users 2 Posts: 5,831 ✭✭✭10000maniacs


    Deleted User wrote: »
    So does this mean we could have a highly infectious HIV like illness on our hands.

    Nope, If HIV was as infectious as COVID, It wouldn't have made it out of Wuhan. It would kill you in a few days.
    Not very good for a virus spreading wise.


  • #4246
    ihdxwz4a3pem9j
    Closed Accounts Posts: 82 ✭✭ihdxwz4a3pem9j


    Be right back wrote: »
    Thank you and all of your colleagues.

    My brother is a Garda. My best-friend’s wife stays at home, and minds the kids, while he goes to work in the hospital. I have been living off take-out. I do my shopping in Tesco. I called the people in revenue the other day. I bought some stuff in pharmacy at the weekend. All of these things are run by hard-working individuals. They all deserve praise and thanks! And the people sitting at home reading this, who cannot work, deserve praise and thanks. It is by staying home and not spreading the virus, that the health service has been able to function so well. Thank you, but the thanks is much deserved by so many!


  • #4247
    joe_99
    Closed Accounts Posts: 763 ✭✭✭joe_99


    ShineOn7 wrote: »
    Are those figures all per head of population?

    The more you test the higher all those figures become. We are one of the top testers on the planet. Don't worry about other countries look at our hospitals and ICUs. They are the reason for the lockdown. To stop them being overwhelmed and hence unable to cope....resulting in unnecessary deaths


  • #4248
    owlbethere
    Closed Accounts Posts: 2,329 ✭✭✭owlbethere


    peasant wrote: »
    And now for something completely different.

    Playmobil have started producing face masks, available in their online shop

    509616.JPG

    LOL. I thought you were joking so I popped over for a look and lo and behold, a playmobil mask. I would prefer a lego mask myself.


  • #4249
    Lackey
    Closed Accounts Posts: 1,118 ✭✭✭Lackey


    Daroxtar wrote: »
    So when is Love Island back?

    July
    They are interviewing now online :D


  • #4250
    smelly sock
    Closed Accounts Posts: 6,820 ✭✭✭smelly sock


    Alisa Odd Wasp wrote: »
    My brother is a Garda. My best-friend’s wife stays at home, and minds the kids, while he goes to work in the hospital. I have been living off take-out. I do my shopping in Tesco. I called the people in revenue the other day. I bought some stuff in pharmacy at the weekend. All of these things are run by hard-working individuals. They all deserve praise and thanks! And the people sitting at home reading this, who cannot work, deserve praise and thanks. It is by staying home and not spreading the virus, that the health service has been able to function so well. Thank you, but the thanks is much deserved by so many!

    All the above are the reason why our children will have a future.

    I cry when i think of the sacrafice they are making.


  • #4251
    DevilsHaircut
    Registered Users, Registered Users 2 Posts: 524 ✭✭✭DevilsHaircut


    Alisa Odd Wasp wrote: »
    The FDA is a board that reviews a medical treatment, and determines if it is safe for administration. They have determined that the evidence for the plasma is equivocal. Hence, they have yet to approve its use in patients. We will have to do proper clinical trials in patients before we know for sure its role. It is only an experimental treatment. A clinical trial has various steps: pre-clinical (you look at a medical therapy in animals, and determine it safe and effective). Phase I (you give it to healthy volunteers- you don’t want to test an experimental therapy on the sickest patients, their bodies are already compromised). Phase 2 (you want to test it on a small group of patients with the disease, to see if it’s effective and safe). Phase 3 (you want to test it on a large group of patients to see if it is effective and safe). We will have to get the plasma through these trials, before we know a) if it is actually effective and b) if it safe. I know that people might feel, sure what have we to lose. But until we know it’s effective and safe, we should not roll out to people.

    Thanks for taking the time to reply.

    I'll just say that the EU guidance says 'empirical evidence also indicates that associated risks are very low. In fact, the procedure is a standard plasma transfusion, where the plasma meets all criteria for safety.'

    I think it's being treated as a blood transfusion (and for compassionate use for the sickest) rather than being a new drug/treatment, which of course needs to go through all of the phases (apart from for emergency/compassionate use authorisation).


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  • #4252
    ShineOn7
    Closed Accounts Posts: 4,550 ✭✭✭ShineOn7


    owlbethere wrote: »
    The best news so far is NASA telling us of an asteroid approaching Earth and from what they can see, it won't collide with Earth.


    To be honest I'd probably take an asteroid wiping us all out in 5 seconds instead of the stress of this and the 2-3 years of absolute shíte we have ahead


  • #4253
    fritzelly
    Registered Users, Registered Users 2, Paid Member Posts: 18,583 ✭✭✭✭fritzelly


    Beechwoodspark wrote: »
    Yes agreed it has been a bad year for news.

    One tiny tiny positive in all this is that air quality has improved with lower co2 emissions. That is one thing in all this I would keep.

    But yeah, other than that I am clutching at straws.

    Less rubbish around as well, but lots more dog sh*t


  • #4254
    joe_99
    Closed Accounts Posts: 763 ✭✭✭joe_99


    Rob A. Bank wrote: »
    The ICU numbers are totally dependent on the triage metrics applied in deciding who is being admitted there.

    Triage hasn't been impacted yet and those metrics haven't changed. Nothing abnormal going on now.


  • #4255
    Funsterdelux
    Registered Users, Registered Users 2 Posts: 3,376 ✭✭✭Funsterdelux


    Kermit.de.frog wrote: »
    https://www.theguardian.com/world/live/2020/apr/14/coronavirus-live-news-cases-worldwide-near-2-million-trump-repeats-who-funding-threat-latest-updates



    :(


    I wonder where frogs are on the list:eek:


  • #4256
    Iamabeliever
    Registered Users, Registered Users 2 Posts: 464 ✭✭Iamabeliever


    Beechwoodspark wrote: »
    Well yeah it is until maybe June July time but The bigger story could be the recovery in second part of the year I choose to be optimistic.

    I would like to think the story of the year would be Leo Varadkar's Masterstroke leading Ireland out of this epidemic in sunny May


  • #4257
    Rob A. Bank
    Registered Users, Registered Users 2 Posts: 1,842 ✭✭✭Rob A. Bank


    ShineOn7 wrote: »
    Are those figures all per head of population?

    They are all reported figures from the HSE. The population figure and the comparisons are from Worldometers.

    https://www.worldometers.info/coronavirus/


  • #4258
    Working class heroes
    Registered Users, Registered Users 2 Posts: 3,894 ✭✭✭Working class heroes


    smelly sock wrote: »
    All the above are the reason why our children will have a future.

    I cry when i think of the sacrafice they are making.

    Get a room the pair of ye.

    Racism is now hiding behind the cloak of Community activism.



  • #4259
    ShineOn7
    Closed Accounts Posts: 4,550 ✭✭✭ShineOn7


    SEPT 23 1989 wrote: »
    The IMF told the truth today

    Very few comments on here about it

    It's a total disaster


    RTE leading with positive spin on it

    "IMF: Irish economy set to return to growth next year"

    https://www.rte.ie/news/business/2020/0414/1130427-imf-expects-world-economy-to-shrink-by-3-this-year/


  • #4260
    Conorregan88
    Registered Users, Registered Users 2 Posts: 17 ✭Conorregan88


    Pinch Flat wrote: »
    I think it's certainly passed the Gareth Brookes fiasco a few years back

    Speak for yourself man, I'm still not over that


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  • #4261
    peasant
    Registered Users, Registered Users 2 Posts: 17,789 ✭✭✭✭peasant


    owlbethere wrote: »
    LOL. I thought you were joking so I popped over for a look and lo and behold, a playmobil mask. I would prefer a lego mask myself.

    no worries ...they don't ship to Ireland anyway (yet) :D


This discussion has been closed.
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