Coronavirus Part IV - 19 cases in ROI, 7 in NI (as of 7 March) *Read warnings in OP*

SeaBreezes wrote: »

You know this virus is not flu, right?

Its a combo of SARS/HIV.

SeaBreezes wrote: »

Yes, it is.
Chinese doctors say autopsies of coronavirus victims suggest the deadly illness is “like a combination of SARS and AIDS” that can cause “irreversible” lung damage even if the patient recovers.

The grim finding was reported on by Communist Party mouthpiece the Global Times on Friday, after a paper by Wuhan doctors published in the Journal of Forensic Medicine earlier in the week went viral on Chinese social media.

“The influence of COVID-19 on the human body is like a combination of SARS and AIDS as it damages both the lungs and immune systems,” Peng Zhiyong, director of the intensive care unit of the Zhongnan Hospital of Wuhan University in Wuhan, told the Global Times.

Dr Peng was commenting on the paper by Liu Liang, a forensic specialist from the Tongji Medical College at Huazhong University of Science and Technology, whose team had conducted nine autopsies of coronavirus patients as of February 24.

“The autopsy results Liu shared inspired me a lot. Based on the results, I think the most important thing now is to take measures at an early stage of the disease to protect patients’ lungs from irreversible fibrosis,” Dr Peng told the outlet.

https://www.news.com.au/lifestyle/health/health-problems/chinese-doctors-say-coronavirus-like-a-combination-of-sars-and-aids-can-cause-irreversible-lung-damage/news-story/f58f19c5eeae99b845c54e2d2b9305ca



Latest coronavirus research by a team of researchers from Nankai University in Tianjin lead by Professor Ruan Jishou, a prominent virologists and genomicist have discovered that the new SARS-Cov-2 coronavirus that causes the Covid-19 disease has a mutated gene that is found in HIV virus. It is this unique feature that sets it aside from the rest of the known coronaviruses.
The study is published this week on Chinaxiv.org, a platform used by the Chinese Academy of Sciences to release scientific research papers before they have been peer-reviewed .( http://www.chinaxiv.org/abs/202002.00082)

These findings have huge implications on the potency of the coronavirus and also what it can cause in humans, not just the Covid-19 disease. Furthermore, the Covid-19 disease should never be compared to like the common cold or influenza virus as this new coronavirus is in a separate league of its own.

Though it has not been peer reviewed, two other studies including one in Europe has confirmed the findings.

The combined findings from the three studies indicates that because of the HIV-like mutations, its ability to bind with human cells could be as much as 1,000 times more potent that the initial SARS virus of 2003.

The findings also indicate that the new SARS-CoV-2 has a ‘dual attack’ approach of binding to human cells.

The first is via the ACE2 receptors found on human cell membranes and it’s a typical mode of most coronaviruses. (The new SARS-CoV-2 coronavirus has a plus 80 percent genomic matching to the previous SARS virus, hence it explains this property that it possesses)

However it must be noted that the ACE2 protein does not occur in large quantities in healthy people, and this partly helped to limit the scale of the SARS outbreak of 2002/2003 which infected close to 8,000 people globally.

As the findings of the new study indicates that the new SARS-CoV-2 coronavirus has a mutated gene similarly found on the HIV virus, it is also able to attack human cells via the target called furin, which is an enzyme that works as a protein activator in the human body. Typically many proteins are inactive or dormant when they are produced and have to be “cut” at specific points to activate their various functions which furin does in the human cellular pathways.

Professor Ruan Jishou and his team at Nankai University in Tianjin discovered this new property of the SARS-CoV-2 when they were doing genome sequencing of the new coronavirus found a section of mutated genes that did not exist in the original SARS virus, but were similar to those found in HIV.

Professor Ruan Jishou told Thailand Medical News via a phone interview, “This finding suggests that 2019-nCoV coronavirus may be significantly different from the SARS coronavirus in the infection pathway and has the added potency of using the packing mechanisms of other viruses such as HIV.”
Another research conducted also this month, by Professor Li Hua , another prominent virologist and genetic specialists, and his team from Huazhong University of Science and Technology in Wuhan, Hubei province, also confirmed Professor Ruan’s findings. http://www.chinaxiv.org/abs/202002.00062

The study indicated that the HIV-like gene found on the new SARS-CoV-2 coronavirus was not detected on any of the other coronaviruses including the MERS, original SARS and even the Bat-CoVRaTG13, a bat coronavirus that was considered the original source of the new coronavirus with 96 per cent similarity in genes.

Professor Li told Thailand Medical News,” This is maybe why the SARS-CoV-2 is more infectious than the other known coronaviruses.”
A European a study by French scientist professor Dr Etienne Decroly at Aix-Marseille University in France, which was published in the scientific journal Antiviral Research , also found a “furin-like cleavage site” that is absent in similar coronaviruses, thus confirming the initial findings as well. (https://www.ncbi.nlm.nih.gov/pubmed/32057769)


https://www.thailandmedical.news/news/breaking-latestcoronavirus-research-reveals-that-the-virus-has-mutated-gene-similar-to-hiv-and-is-1,000-times-more-potent-

GM228 wrote: »

First case reported in the Vatican, I guess there is no divine intervention afterall.

starbaby2003 wrote: »

Again why only people able to read medical literature should be allowed relay it in lay terms.

SeaBreezes wrote: »

Yes, it is.
Chinese doctors say autopsies of coronavirus victims suggest the deadly illness is “like a combination of SARS and AIDS” that can cause “irreversible” lung damage even if the patient recovers.

odyssey06 wrote: »

Not suggesting total dysfunction\existential threat but this worst case scenario from the UK does suggest considerable strain on the state's ability to function:

https://fortune.com/2020/03/03/u-k-warns-companies-that-20-percent-of-workforce-could-be-out-as-coronavirus-cases-rise/
British businesses were warned as many as 20% of their workers could be forced to take time off during peak periods of infection if the U.K. is hit by a widespread outbreak of coronavirus.
As the number of confirmed infections in the U.K. rose to 51, the government published its plan for dealing with the disease. It included an estimate that in a worst-case, a fifth of the workforce — more than 6 million people — could be absent.
This would have knock-on effects, as others would be forced to take time off to care for those who are ill, or to look after children if schools are closed. Such a peak period of infection would be likely to last around three weeks, the government said.

MOR316 wrote: »

And when you cough, it sounds like Liam Neeson chasing a load of chickens around in a barrel