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The Ivermectin discussion

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Comments

  • Registered Users Posts: 382 ✭✭Unicorn Milk Latte


    Yes, but while that is true (Mercola had to remove claims that vitamin D cures Covid from his website after FDA warnings), the main point I was trying to make is that there are scammers like Mercola who create antiqvax FUD for the mere purpose making money - like selling generic vitamins at insane prices.



  • Registered Users, Registered Users 2 Posts: 32,136 ✭✭✭✭is_that_so



    The Washington Times is in the anti-Biden camp anyway and we know what Malone is and it's nothing to do with mRNA vaccines. They really do fete their celebrity "scientists" over there and let them away with murder.



  • Posts: 0 [Deleted User]


    I'm on the "more data required" side of the Ivermectin thing, but it's not true that we know nothing about Ivermectin. It's a drug that's been in human use for nigh on forty years, has been dosed in the billions, has a good safety profile, is on the WHO list of essential medicines, and has shown antiviral properties in-vitro against a good number of viruses (its effects against chikungunya and yellow fever are currently being studied).

    The all-out attacks on ivermectin make me a little crazy. They are disinformation in and of themselves, and when strongly-worded articles or frothy, rabid forum posts pop up saying, essentially: "lol idiots want to use a horse parasite drug instead of getting a vaccine", they raise my brow. I've seen some ostensibly serious journalists describe Ivermectin as a "drug used to de-worm livestock" and never even mention that it has been used in humans in any capacity, much less been considered an essential medicine by the WHO.

    It is easy to see why people who think Ivermectin works would want to push ahead with treatment: if a therapeutic were as effective as some apparently believe Ivermectin to be, then it would indeed be unethical not to do all one could to advocate for its use in frontline medicine. The motivation of those who seem hell-bent on ensuring Ivermectin is considered to be dangerous, ineffective, animal-only drug for conspiracy theorists, Trump supporters and kooks, while trials are ongoing? Well that is much less clear.



  • Registered Users Posts: 2,110 ✭✭✭The Raging Bile Duct


    I've no doubts that Ivermectin has many benefits, it just caused a raised a raised eyebrow when I saw it being promoted as the treatment that works from people I know on facebook that are extraordinarily anti-vax and anti-mask - a quick google seemed to indicate that the jury was still out on its effectiveness and more trials were needed. From my own viewpoint, I just don't understand why Ivermectin is acceptable to these people but masks and vaccines are not.



  • Registered Users, Registered Users 2 Posts: 16,906 ✭✭✭✭astrofool


    I'm in the group that it would be awesome if it was proven to work as it's one more medicine in the arsenal to fight COVID with, however, working against that is the lack of well run studies despite there being no barriers to doing so (other medicines have been through studies already and deemed good to use or eliminated), the fact that any company can make and sell it as a generic but have chosen not to and the very very grifty people that have latched onto it and are pushing it, I mean, the Malone, long COVID piece was one of the classic ploys to eliminate people who won't fall for it and ensure those you're targeting are easily manipulated (e.g. the Nigerian prince email scam).



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  • Posts: 0 [Deleted User]


    Yeah. In the interest of disclosure, I am vaccine hesitant. But I'm not on the Ivermectin bandwagon other than thinking it's a good idea to be investigating as many potential therapeutics as possible, if they have shown in-vitro promise. Ivermectin could be as good as the most optimistic papers say or as useless as the most pessimistic, and right now there's just too much noise to make a prediction either way. I hope the PRINCIPLE study will shed some light, when the Ivermectin phase is completed.

    I'm aware that there are some oldskool anti-vax, anti-mask types out there who think ivermectin is being suppressed by Big Tech so that Gates can get his 5G magnet into their arm and Big Pharma can restock Nancy Pelosi's child-luring ice cream freezer so that she, Ursula and Klaus can turn us all into techno-serfs under the control of a one-world, China-lead government. But those people are not going to be reached by information that is just as crazy (as far as Ivermectin goes) in the other direction, when descriptions like "toxic horse paste" are easily shown to be the propagandistic nonsense that the conspiracy theorists claim is everywhere and about everything.

    Those people will probably not be reached by anything, in fact, so if those sort of articles and posts achieve anything, aside from giving those who are already "against" Ivermectin and have a general dislike for those who put their faith in it as a wonder drug a warm tingle of smugness for ten minutes, the it is to make people who are on the fence, or who have looked into Ivermectin and come to the conclusion that most of us here seem to have come to (ie. that Ivermectin ought to be investigated properly but there is no clear signal yet either way), wonder why, exactly, there is such obvious pressure to make sure that the reputation of a molecule is tainted. And in turn to damage the trust they have in what ought to be our general instruments of sense-making. As I said: hard to understand the motivation.



  • Registered Users, Registered Users 2 Posts: 31,141 ✭✭✭✭Lumen


    @[Deleted User] wrote

    ..descriptions like "toxic horse paste" are easily shown to be the propagandistic nonsense..

    "Horse paste" is not propaganda, it is literally what some loons are taking, the toxicity comes (presumably) from getting the dosage wrong.



  • Posts: 0 [Deleted User]




    Between these two, Dr. Kataria/FLCCC, if I or my family get sick we will be following some of the things they suggest

    (not Ivermectin by FLCCC - cant get it in Ireland and am not entirely sure of its efficacy).

    In a years time we could be using Ivermectin as a preventative aid and treatment.

    I can see why it is used in India and USA as its something they use, but its not a drug we use much of historically in Europe. Hiqa reports in 2021 seem to be its unlikely to be suitable in an irish care setting.

    Some of the other things such as vitamins, nasal sprays, mouthwash, breathing exercises to improve lung function are common sense.

    Dr. Katarias video, no fancy treatments, just a lot of common sense.

    Getting your body through in the best possible shape during that inflammatory stage.

    She seems like a really good doctor, we need doctors of her calibre in this country (4 million youtube views - i suggest many of which are Indian).

    Post edited by [Deleted User] on


  • Posts: 0 [Deleted User]


    I believe at this stage (18 months in) the above is true.



  • Posts: 0 [Deleted User]


    Post edited by [Deleted User] on


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  • Posts: 0 [Deleted User]


    Describing Ivermectin as "toxic horse paste" absolutely is propaganda, if that is the only information given about the molecule in the piece. Explaining that some people have taken anti-parasitic horse paste in pursuit of Ivermectin because it is not proven effective and therefore not licensed for use against Covid-19, and that those products are inconsistent and dangerous is a different thing. Far, far too many examples of the former appearing in what are ostensibly reliable media outlets.



  • Registered Users, Registered Users 2 Posts: 302 ✭✭Piollaire




  • Registered Users Posts: 382 ✭✭Unicorn Milk Latte


    The all-out attacks on ivermectin make me a little crazy. They are disinformation in and of themselves, and when strongly-worded articles or frothy, rabid forum posts pop up saying, essentially: "lol idiots want to use a horse parasite drug instead of getting a vaccine", they raise my brow.


    You do realise that Ivermectin Horse dewormer is sold out on Amazon, because actual people here in the real world are buying it for Covid protection and treatment. Feel free to go to amazon.com and find Ivermectin horse paste from different resellers, and then look at the comments from people who bought this.

    Yes, these people who are afraid of getting a vaccine that has been administered to millions without issue, but are not afraid of ingesting horse paste, have a screw loose.


    No-one ever claimed Ivermectin is ineffective as horse dewormer, or that the variants sold for human consumption are ineffective in what they are actually supposed to treat. Straw man.



  • Registered Users Posts: 325 ✭✭virginmediapls



    Looks like complete and total horseshit. No science, sentences poorly constructed, made up figures.


    Absolute **** tripe.



  • Registered Users Posts: 382 ✭✭Unicorn Milk Latte


    It looks interesting for what it is - a study based on a clinical trial that is not yet peer reviewed, that looks into

    Efficacy of a nasal spray containing Iota-Carrageenan in the prophylaxis of COVID-19 in hospital personnel dedicated to patients care with COVID-19 disease


    So, not a Covid treatment, prophylaxis only, not a replacement for vaccines, and only intended for health care workers in a Covid ward.



    The study came out before vaccines were widely available. It states:

    Implications of all the available evidence A simple intervention such as the administration of a nasal spray with Iota-Carrageenan, in addition to hand hygiene, use of personal protective equipment and social distancing, could provide additional protection until vaccines can be administered to the majority of the population.



  • Posts: 0 [Deleted User]




  • Posts: 0 [Deleted User]


    100's of Nasal sprays developed in last year.

    All of them help in some way or another.



  • Posts: 0 [Deleted User]


    A study conducted in healthcare workers does not mean the subject of the study is only intended for healthcare workers.

    I’ve used a HPMC nasal powder for a long time to ward off allergens, but I make sure to use one any time I’m going anywhere that’s likely to be crowded now.



  • Posts: 0 [Deleted User]


    I have bought several brands in the last 18 months:

    Viraleeze

    Taffix

    Enovid


    Enovid and taffix have HPMC.

    Taffix claims 78% protection from trial in 2020.

    Enovid claims it can reduce viral load by 95% after one day of treatment in covid positive persons.

    99.9% after 3 days treatment in phase 2 trial in UK hospital.

    They all use similar ingredients HPMC, Carrageenan, Astrodiner Sodium.

    There is something to them I believe.

    Post edited by [Deleted User] on


  • Posts: 0 [Deleted User]


    https://c19adoption.com/

    Good databases of all theraputics/updated trial data.

    Enormous the amount of work going on and very heartening.



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  • Registered Users Posts: 382 ✭✭Unicorn Milk Latte


    Enormous the amount of work going on and very heartening.


    Very true.

    In the spirit of staying positive - I know this will sound like science fiction, but bear with me for a moment: one could imagine that a medication could be developed where, instead of having to spray your nose 3 times a day for moderate protection, one could have one or two single small injections of a hypothetical drug, that would prevent death and hospitalisation altogether.

    I know this sounds a little insane - after all, new drugs need to go through a lengthy testing process till they are considered safe and available to the public. But imagine that one could speed up this testing process, by starting several tests at the same time, rather than doing them one after another. Same safety standards, faster approval. Some brilliant minds could come up with something like that.


    So, if we stay positive - I know we want to - could we imagine something like that, maybe in the not too far future?



  • Registered Users Posts: 2,110 ✭✭✭The Raging Bile Duct


    That's some bizarro fantasy land you're living in there, bucko. I have something you might have heard about called an immune system so you cling to those dreams and I'll stick to my 12 vitamin D tablets a day and 20 minutes of shining a UV light up my hole.



  • Registered Users Posts: 382 ✭✭Unicorn Milk Latte


    That may not work much longer. You may have heard of a new nefarious government program that is called 'vaccination'. It has the sole purpose of making people more compliant. Obedient. Sheep like.

    There have been many people critical of this government measure, and refused to have it done to them.

    But - and this is shocking news - the government has now developed a new biological weapon that targets only the unvaccinated, and makes a lot of them very sick. Some even die. Just to retaliate, because they don't comply with their vaccination scheme.

    This new weapon is called the 'Delta Variant' in government speak.



  • Posts: 0 [Deleted User]


    4th trial of fluvoxamine results out (see above).

    All 4 trials have shown early treatment significantly reduces severe covid.

    This is a complex disease that needs multi-pronged approach:

    • Vaccines
    • Anti viral treatments.
    • Anti-inflammatory treatments.
    • Anti-coagulant treatments.

    Excess inflammation in the lungs and or blood clotting in the body is what kills.

    This whole family of SSRI's is worth investigation.

    They seem to attack covid virally, reduce inflammation and reduce coagulation.

    Looks like a winning combination.

    4 out of 4 aint bad.

    Fluvoxamine can have a few side affects nausea etc.

    Fluvoxetine and Sertaline I heard are better tolerated by patients and look as impressive.


    Post edited by [Deleted User] on


  • Registered Users, Registered Users 2 Posts: 13,998 ✭✭✭✭Cuddlesworth


    Just wait till you find out about the common SSRI side effects.



  • Registered Users, Registered Users 2 Posts: 32,136 ✭✭✭✭is_that_so


    This is all well and good but have any of them produced enough data on COVID that a regulatory authority might use to approve them? Most people would not be happy to take something like this off the back of small trials and the say so of some doctor pushing treatments.



  • Posts: 0 [Deleted User]


    How many countries have allowed its use for covid?

    In europe it is currently Slovakia and Czech Republic.

    Ireland are only using it for ICU patients.



  • Registered Users Posts: 142 ✭✭spalpeen


    Ivermectin? That is not being used in Irish hospitals. There is no more evidence for its efficacy against covid than there is for peanut butter. Source: I'm a doctor



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  • Posts: 0 [Deleted User]


    Apologies I must have just made the above up, while your valid source knocked down my argument completely.

    Apologies again Doctor.

    Whats your early care plan for covid?

    All I can see in ireland is stay at home with covid

    and take no treatment until your lips turn blue.

    Two weeks after infected go to the hospital.

    Obviosly the most optimal care.

    Brilliant 18 months into a pandemic.

    I have heard annecdotely of irish doctors taking horse paste ivermection as prevention from covid.

    History will not remember this time kindly how hse/nphet and other authorities around the world have dealt with early treatment of covid.

    Nothing in irelands case.

    I have taken the vaccine as have most of the population and covid is rampant.

    We listened to the doctors and hse about vaccines and hospital numbers are going up every day.

    Look how eastern europe are doing for last 3-4 months who are widely using this.

    In many eastern european countries you can order it from a pharmacy as soon as you are sick with covid.

    Look how quickly Delta wave came down in India.

    Do they use Ivermectin in India?

    In Africa?



  • Registered Users Posts: 142 ✭✭spalpeen


    I'm not sure how reputable that website is but in any case it says that was a trial, not an endorsement of evidence. No patients are receiving ivermectin in Ireland for covid as standard treatment. We have a vaccine in less than 12 months which is unprecedented in medical history. Get your vaccine. If you still get sick go to hospital. There are treatments such as oxygen, dexamethasone, remdesivir, and the various monoclonal antibodies.



  • Posts: 0 [Deleted User]


    Its better evidence in fairness than your anecdote.

    Got vaccine as did my neighbour and all their family.

    Their whole family is at home sick with covid presently (not in great shape at present).

    Vaccines cannot be seen in a vacumn by hse.

    There is more in hospital in NI at present than their first wave and have high vaccination levels.

    Vaccines alone is not good enough and I'm sorry but GPs are doing very little other than telling patients youve been sick long enough at home go to a hospital. That is not great care.

    Treatments in a hospital: when you have been infected for two weeks (incubation 5-6 days) and then sitting at home for 8-9 days.

    You dont think those people (40 a day currently) would be better served with early outpatient treatment to avoid hospitals and to be in better shape when they get in their.

    The damage is done by the time they are in hospital.



  • Registered Users, Registered Users 2 Posts: 6,247 ✭✭✭Former Former Former


    It's an anti vaccine propaganda website. Take everything on it with a massive pinch of salt.



  • Posts: 0 [Deleted User]


    It will be a treatment here in the future.

    How else do you explain covid clearing up so quickly in india.

    We let high covid stick around like a bad smell.

    Every doctor prescribing this to sick and non sick in india, reduced r rate.

    It could be as good as vaccines, look at eastern europe.

    We need a multi-pronged approach.

    Through everything at covid to reduce cases.



  • Posts: 0 [Deleted User]


    We need Ivermectin use in your europe.

    Vaccines + ivermectin = return to normaility.

    Covid will then be the flu that we can live with.



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  • Registered Users Posts: 382 ✭✭Unicorn Milk Latte


    Meanwhile in the US, Ivermectin is used on prison inmates, against explicit advice from the FDA:



    The article also, once again, brings up horse dewormer paste:

    Last week, the FDA tweeted out a page with information about ivermectin, mentioning that they had received multiple reports of patients requiring medical support and getting hospitalized after self-medicating with ivermectin intended for use on horses. The information they release said the drug, even when prescribed to humans to treat skin conditions or lice, is not an antiviral drug.



  • Posts: 0 [Deleted User]


    Misinformation aside, how do the doctor's results stack up with general Covid statistics?

    That article says there have been 500 cases in the prison and one short hospitalisation, zero deaths. That seems... pretty good, no?



  • Registered Users, Registered Users 2 Posts: 302 ✭✭Piollaire


    The sheriff is talking horse sense

    The FDA reminds me of the Ordnance Department in the US during World War II that refused to develop heavy tanks while tank crews in Shermans got slaughtered.

    Post edited by Piollaire on


  • Registered Users Posts: 2,110 ✭✭✭The Raging Bile Duct




  • Registered Users, Registered Users 2 Posts: 69,588 ✭✭✭✭L1011


    A few pages ago you stopped pushing Ivermectin as there was no evidence of it working, and moved on to on anti depressants instead. Why have you gone back to pushing unproven veterinary medicines?



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  • Posts: 0 [Deleted User]


    There was and is drugs out there that were effective in the treatment of covid but we weren't fed that narrative. Instead we were ferried down the road of vaccination being the only solution. The whole response to covid was worse than covid itself. This video explains it better from an actual doctor who is more than qualified to judge.




  • Registered Users, Registered Users 2 Posts: 6,247 ✭✭✭Former Former Former


    It's mad that, out of the millions of doctors around the globe, it's the same four or five who keep popping up undermining vaccines and promoting these unproven therapies.

    If you exclude contributions from Robert Malone, Peter McCullough and Pierre Kory, probably 80% of this stuff just ceases to exist.

    If this is as much a slam-dunk as is claimed, why is it such a small circle of medics hyping it?



  • Posts: 0 [Deleted User]


    Most Doctors who endorse ivermectin are not against vaccines.

    Pierre is vaccinated as is family and his parents.

    He got covid a few weeks ago and took ivermectin.

    The anti ivermectin brigade try to make out people who take ivermectin are anti vaccines.

    The amount of stories I have heard this week in ireland of people getting covid after vaccine is shocking.

    Get vaccinated as mitigation, but there also has to be a plan b.

    You stick to your principles, being pragmatic is better.

    Your question about ivermectin is why is it not widely used:

    Its is widely used in:

    South America

    Growing in North America(despite regulatory difficulties).

    Africa

    Asia - India, Malyasia etc.(not in china, south korea, japan due to extreme covid suppression endorsed by countries).

    Not in Austrailia/New Zealand (due to zero covid).

    Eastern europe - slovakia, czech republic, romania etc.

    The only place it is not widely used in the world is western europe despite high levels of vaccines and high levels of covid.

    We are the outlier not everyone else.

    There is 7 billion people on the globe and western europe make up less than 15% of population.

    China make up 20%, but there is no ivermection there as there is no need for it at present.



  • Posts: 0 [Deleted User]


    A few pages ago you stopped pushing Ivermectin as there was no evidence of it working, and moved on to on anti depressants instead.

    Why have you gone back to pushing unproven veterinary medicines?



  • Posts: 0 [Deleted User]


    Please read.

    Both are in there.

    Or ignore, i dont really care.

    Factually what you have said above is untrue.

    I didnt "stop pushing".

    I was sitting on the fence with ivermectin.

    I do believe it works and is another mitigation against severe covid.

    I dont believe current vaccines will stop you getting covid and believe we need an early treatment than

    sitting at home hoping youll get better.

    Most will, many wont.

    My neighbour and all the family are fully vaccinated and infected currently.

    All in bad shape at this stage.

    Not the most ringing endorsement of vaccines.

    Im vaccinated and believe eevryone should take one, but it will not end this crisis or of people going everyday

    to hospital with covid.



  • Registered Users, Registered Users 2 Posts: 6,247 ✭✭✭Former Former Former


    It is "growing in North America" in a certain politically-motivated sector of the population who don't even believe in mask wearing. It is absolutely not based on clear-headed analysis of the data.

    As for the rest of your post, the conclusion is that the first world, with the best healthcare services, the most doctors, best researchers and probably 98% of global knowledge and experience in drug development, have completely missed the boat, while the third world has nailed it?

    It's possible, but it's also possible that these countries are desperate enough to try anything.

    I'd also say you're over-stating the extent to which ivermectin is actually used in these countries.



  • Registered Users Posts: 435 ✭✭godzilla1989


    DELETED



  • Registered Users Posts: 382 ✭✭Unicorn Milk Latte


    I'm honestly not sure if you're just trolling, or if you really have no clue how to systematically determine the efficacy of medications - like double blind studies with placebo control groups.



  • Posts: 0 [Deleted User]


    So you think western europe including (Ireland) have nailed it.

    Circa 50 people today will be wheeled off to hospital, infected 2 weeks ago and the hse has told them to take nothing more than a painkiller for treatment in that time.

    While the rest of know we will all eventually be infected with covid due to high case numbers daily and vaccines that wane within a few months of being

    injected.

    Look how quickly indias delta wave went down and low cases/deaths presently despite being a "third world country" and over a billion people.

    Look how well eastern europe is doing currently.

    The worst hit countries in all of this is in your 98% club.

    NI is having a worst wave of hospitalisations and deaths currently than in its first wave.

    Despite high level of vaccinations and access to "best doctors and best reasearchers".

    Get out of it.



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