What exactly is happening with AstraZeneca?

Ashbourne hoop · 07-04-2021 02:51PM

stephenjmcd wrote: »

Numbers from MHRA Chief Executive

79 reports of blood clots after first #AstraZeneca dose
51 women / 28 men
19 died
3 were under 30

Equates to 4 in 1 million doses dispensed ie ‘very rare’

The 3 under 30 is worrying though, particularly for a virus that doesn't generally cause death in that age group. The news will have a negative effect on the AZ roll out.

LLMMLL · 07-04-2021 02:53PM

Lesalare wrote: »

Most/all of that medication has been tested for a heck of a longer time than these vaccines.

New medication comes on the market all the time. And people happily take it. Have you researched how long every medication you’ve ever taken has been on the market?

I wish people would just be honest about how they assess risk rather than pretend they are being rational. The fact that this is in the newspapers and a media fuss is being made is what is scaring people. The numbers are not at all scary.

embraer170 · 07-04-2021 02:54PM

Probes wrote: »

Aren’t a third of people dying from this side effect? Wouldn’t that equate to 1 in 10,000 dying from the pill?

How many die from taking the pill?

Turtwig · 07-04-2021 02:54PM

Ashbourne hoop wrote: »

The 3 under 30 is worrying though, particularly for a virus that doesn't generally cause death in that age group. The news will have a negative effect on the AZ roll out.

If there was no vaccine given what do you think the number under 30 would be?

That there were 3 reported doesn't necessarily mean the vaccine was the reason.

stephenjmcd · 07-04-2021 02:55PM

To clarify a few posts here

https://twitter.com/kateferguson4/status/1379806860287561729?s=19

https://twitter.com/kateferguson4/status/1379806461702905863?s=19

07-04-2021 03:00PM

I think I'll pass on that jab. Do we find out which brand we are being offered?

_Whimsical_ · 07-04-2021 03:01PM

ACitizenErased wrote: »

Exact same symptoms. EMA agreed they're the same, I'm watching the press conference right now and they compared them.

A comparison seems quite disingenuous on their behalf then.

DVT and CSVT caused by thrombocytopenia are too very different situations. Every DVT does not end up lodged in your brain. CSVT by it's nature is describing that situation.

I feel like they need to tell us what the outcomes have been for those affected. Did they recover fully or are those who are alive impacted by the typical aftermath of stroke/cerebral haemorage. Deaths alone do not tell the full story.

robinph · 07-04-2021 03:02PM

Turtwig wrote: »

If there was no vaccine given what do you think the number under 30 would be?

That there were 3 reported doesn't necessarily mean the vaccine was the reason.

39 deaths of people aged 20-29 in January 2021 in the UK from Covid:

https://www.gov.uk/government/publications/covid-19-reported-sars-cov-2-deaths-in-england/covid-19-confirmed-deaths-in-england-report

_Whimsical_ · 07-04-2021 03:05PM

stephenjmcd wrote: »

To clarify a few posts here

https://twitter.com/kateferguson4/status/1379806860287561729?s=19

https://twitter.com/kateferguson4/status/1379806461702905863?s=19

This does not bode well.
Lots between 30 and 40 aren't afraid of the illness anyway and will refuse the vaccine on the basis of why would it be safe for me but not my friend 2 years younger etc.
They'd have been much wiser to make a cut of off 45 or so. They'll really screw the effort and our hope of herd immunity now.

LLMMLL · 07-04-2021 03:08PM

_Whimsical_ wrote: »

This does not bode well.
Lots between 30 and 40 aren't afraid of the illness anyway and will refuse the vaccine on the basis of why would it be safe for me but not my friend 2 years younger etc.
They'd have been much wiser to make a cut of off 45 or so. They'll really screw the effort and our hope of herd immunity now.

Lots of people in their 50s aren’t scared of it either. By that logic the cutoff should be 60.

It’s not the government or medical boards who will screw this up. It’s the people who will incorrectly assess their risk and refuse the vaccine.

josip · 07-04-2021 03:09PM

_Whimsical_ wrote: »

This does not bode well.
Lots between 30 and 40 aren't afraid of the illness anyway and will refuse the vaccine on the basis of why would it be safe for me but not my friend 2 years younger etc.
They'd have been much wiser to make a cut of off 45 or so. They'll really screw the effort and our hope of herd immunity now.

AZ represents only a quarter of our future supply.
Bearing in mind the 12 week dosing interval, we would probably arrive at herd immunity no later, if we use a later tranche of another vaccine instead.
(If you're in the UK, then things may be different)

Jane1012 · 07-04-2021 03:10PM

My maternity hospital have me booked in for it in the next few day’s. I’m very nervous to get it being early 30s (and obviously pregnant) but I think I just have to go with it now, I’m very terrified of COVID so I hope it’s the lesser of 2 evils!

Wanderer78 · 07-04-2021 03:10PM

Deleted User wrote: »

I think I'll pass on that jab. Do we find out which brand we are being offered?

i didnt until i was at the center, could be different for others

josip · 07-04-2021 03:11PM

Jane1012 wrote: »

My maternity hospital have me booked in for it in the next few day’s. I’m very nervous to get it being early 30s (and obviously pregnant) but I think I just have to go with it now, I’m very terrified of COVID so I hope it’s the lesser of 2 evils!

I didn't know any vaccine was approved for pregnant women ?

Strazdas · 07-04-2021 03:12PM

josip wrote: »

I didn't know any vaccine was approved for pregnant women ?

They all are : pregnant women are not exempt from receiving any of the vaccines (they are considered safe to administer).

Wanderer78 · 07-04-2021 03:13PM

josip wrote: »

I didn't know any vaccine was approved for pregnant women ?

yea looks like some women are taking it, depending on where theyre at

Mitch Connor · 07-04-2021 03:13PM

josip wrote: »

I didn't know any vaccine was approved for pregnant women ?

wife was telling me about guidance this morning.

Should have it as soon as possible within pregnancy and not after week 30 (i think).

Ashbourne hoop · 07-04-2021 03:13PM

Wanderer78 wrote: »

i didnt until i was at the center, could be different for others

I think that's the case for everyone

Jane1012 · 07-04-2021 03:14PM

josip wrote: »

I didn't know any vaccine was approved for pregnant women ?

No vaccines are approved for anyone actually... but we are all getting them! It’s if you are high risk of exposure or of illness...

https://www2.hse.ie/screening-and-vaccinations/covid-19-vaccine/getting-your-vaccine/pregnancy.html

Jane1012 · 07-04-2021 03:15PM

Mitch Connor wrote: »

wife was telling me about guidance this morning.

Should have it as soon as possible within pregnancy and not after week 30 (i think).

Yes it’s between 14 and 33 weeks.
That’s another issue I have, I’m 24 weeks so will either need the second dose in 9 weeks (instead of 12) or at a much later stage....

Ashbourne hoop · 07-04-2021 03:18PM

Turtwig wrote: »

If there was no vaccine given what do you think the number under 30 would be?

That there were 3 reported doesn't necessarily mean the vaccine was the reason.

I've no idea what the number would be without the vaccine, not sure if it's that important in this discussion anyway.

Absolutely it doesn't mean the vaccine was the reason, but it is concerning, particularly as it's in an age group that hasn't been widely vaccinated at this stage. If there were more vaccines given to that age group would there be more deaths ?

BTW I've had the first dose of AZ and will get my 2nd when called.

Strazdas · 07-04-2021 03:23PM

Jane1012 wrote: »

My maternity hospital have me booked in for it in the next few day’s. I’m very nervous to get it being early 30s (and obviously pregnant) but I think I just have to go with it now, I’m very terrified of COVID so I hope it’s the lesser of 2 evils!

The only thing I'd say to you is that any risk is extremely low. It seems we haven't had a single serious blood clot case in Ireland with AZ this year, so that should be reassuring to you.

patnor1011 · 07-04-2021 03:27PM

_Whimsical_ wrote: »

This does not bode well.
Lots between 30 and 40 aren't afraid of the illness anyway and will refuse the vaccine on the basis of why would it be safe for me but not my friend 2 years younger etc.
They'd have been much wiser to make a cut of off 45 or so. They'll really screw the effort and our hope of herd immunity now.

Why would they screw the effort or herd immunity? Since none of offered vaccines do not guarantee immunity from infection then unvaccinated people will simply acquire natural immunity when they contract infection.

07-04-2021 03:28PM

Jane1012 wrote: »

No vaccines are approved for anyone actually... but we are all getting them! It’s if you are high risk of exposure or of illness...

https://www2.hse.ie/screening-and-vaccinations/covid-19-vaccine/getting-your-vaccine/pregnancy.html

Exactly Hobsons choice.

In austrailia uptake is poor. My sisters are there and many people not taking it as risk of covid exposure is 0% currently.

Here we just have to go for it. 2% chance of being hosptitalised with covid in my age group or a one in a million chance of dieing of a blood clot. Choice made if im offered astra. Dont overthink it. We need this vaccine to tame covid in this country over next three months. A million doses in next three months. UK pragmatic as ever. Under 30 you will have choice of vaccines as covid risk is generally quite low. Just get on with jabbing needles into shoulders. Benefits outweigh risks individually and societally. Its that simple.

07-04-2021 03:55PM

correct horse battery staple wrote: »

Took 19 people to die before action was taken with initial howls in tabloids and Brexiteers on boards about how the UK vaccine is being unfairly treated.

Let’s see what happens here

Unfair statement.

18 million britains vaccinated with AZ.

How many lives did that save from covid (directly and indirectly through spread reduction) now and in the future?

This time last year in UK 1000 people dieing a day.

Now under 50 per day and dropping.

Its all about the big picture and public good.

I would take a one in million chance of dieing of blood clot to restore normal life.

07-04-2021 04:23PM

correct horse battery staple wrote: »

Took 19 people to die before action was taken with initial howls in tabloids and Brexiteers on boards about how the UK vaccine is being unfairly treated.

Let’s see what happens here

your posts get increasingly more and more bizarre :rolleyes:

take everything · 07-04-2021 04:24PM

Jane1012 wrote: »

My maternity hospital have me booked in for it in the next few day’s. I’m very nervous to get it being early 30s (and obviously pregnant) but I think I just have to go with it now, I’m very terrified of COVID so I hope it’s the lesser of 2 evils!

I think it is awful that people are taking a vaccine under what seems like duress and not given a choice.

Everyone else who wants to take AZ, fire ahead. But people should be given a choice.

Supposed supply issues or not.

Jane1012 · 07-04-2021 04:34PM

take everything wrote: »

I think it is awful that people are taking a vaccine under what seems like duress and not given a choice.

Everyone else who wants to take AZ, fire ahead. But people should be given a choice.

Supposed supply issues or not.

Yes I literally feel like I have no other option, I know many on here have said take what you’re given or to the back of the q and while I understand that to a certain degree I still think I should be given a plan B. I’m afraid if I say no it’ll be months before I get another opportunity - even though I remain high risk.
I literally am running out of time to get it, I need to have it before 33 weeks pregnant and if I don’t get it before then I face going in to labour while being terrified of contracting covid and dying (due to my other risk factors). Id understand if it was a case of this is the only vaccine available, but it’s not there’s 2 other options I could be given right now, and AZ is not even the majority of our supply either. What’s worse is, I am being given it in a hospital so the issue of storage temps etc are not there either.

07-04-2021 04:35PM

take everything wrote: »

I think it is awful that people are taking a vaccine under what seems like duress and not given a choice.

Everyone else who wants to take AZ, fire ahead. But people should be given a choice.

Supposed supply issues or not.

You dont have to take it.

You probably will get a choice if you refused but could be months later.

We are all in the same boat.

Risk of covid vs. one.in a million chance of death of blood clot

We always have choices....

People being offered a vaccine now the choice should be alot easier as covid risk is alot higher than someone very young and no underlying.

Older over 70s should have given either vaccine. This added to peoples worries over az and meant more younger could not get pfzier if they wanted. Also over 70s had to wait longer to get first jab. Blame tony holihan for that one. I hope glynn takes over permanently tbh. He should have left in June and came back following June.

Turtwig · 07-04-2021 04:52PM

[Deleted User] wrote: »

Risk of covid vs. one.in a million chance of death of blood clot

You are conflating risk on a population level with risk to a individual. A random person in a population pool may have odds of 1 in a million. A specific individual with specific medical history may have very different odds. They need to discuss their concerns with their medical team and if they don't feel their medical team are able to answer their concerns they should ask for their medical team to seek to those answers or refer them to someone who can.

Please can we stop telling posters with concerns here that their odds are 1 in 4 million. That may or may not be the case depending on their individual details.

In the coming weeks the EMA will publish even more details that should hopefully help stratify the risk even further.

What exactly is happening with AstraZeneca?

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