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Covid 19 Part XXXIV-249,437 ROI(4,906 deaths) 120,195 NI (2,145 deaths)(01/05)Read OP

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Comments

  • #2912
    muddypuppy
    Registered Users, Registered Users 2 Posts: 322 ✭✭muddypuppy


    is_that_so wrote: »
    Story about celebs ending up in Australia, including our own refugee Matt Damon. Needless to say some of the 40,000 normal stranded Aussies are not happy about it.

    https://www.bbc.com/news/world-australia-55851074

    Remember, we are all in this together.


  • #2913
    Sobit1964
    Registered Users, Registered Users 2 Posts: 550 ✭✭✭Sobit1964


    Banana Republic 1 wrote: »
    France has discovered a variant that can’t be picked up by current pcr test.

    Off hand do you know if it is detected by the anal swab that the chinese are using?


  • #2914
    funnydoggy
    Registered Users, Registered Users 2 Posts: 2,065 ✭✭✭funnydoggy


    Banana Republic 1 wrote: »
    France has discovered a variant that can’t be picked up by current pcr test.


    They discovered it over 2 weeks ago. I don't think it's of too much concern, or we'd hear a lot more about it.


    I'd happily eat my words though!


  • #2915
    podgeandrodge
    Site Banned Posts: 5,975 ✭✭✭podgeandrodge


    podgeandrodge wrote: »
    Germany stopped AstraZeneca again for under 60's:

    "On Tuesday morning hospitals in four German states, including Berlin’s Charité clinic, suspended use of the vaccine on staff members under 60, in particular women, after registering 31 cases of a rare blood clot in the brain among those who had received an AstraZeneca jab.

    He added that public trust in the British-Swedish vaccine was likely to be affected negatively after this second halt in its use. A survey last week suggested that nearly a quarter of Germans would be wary of accepting the AstraZeneca jab.

    Among 31 German cases of blood clots which lead to its suspension were some 19 cases of thrombopenia, where a lower-than-normal level of blood platelets lead to symptoms including excessive nose bleeds. All but two cases involved women between 20 and 63. The two men affected were 36 and 57 years old    ."

    Irish Times:

    "Germany’s Covid-19 vaccination timetable was thrown into disarray yet again after its vaccine commission recommended a temporary halt on the use of the AstraZeneca vaccine in people below 60 years of age.

    The announcement on Tuesday afternoon followed a similar decision by Canada to suspend the use of the vaccine in adults younger than 55.

    Chancellor Angela Merkel held an emergency meeting with state leaders on Tuesday evening to discuss the consequences of the ban. Germany’s health authorities have promised a decision by the end of April about how to proceed with people who are awaiting their second AstraZeneca jab    ."
    Happydays2020 wrote: »
    Has this issue arisen in the UK? They are presumably far ahead on numbers of this vaccine?

    https://www.rte.ie/news/world/2021/0402/1207578-britain-vaccine-clots/


  • #2916
    User1998
    Registered Users, Registered Users 2 Posts: 9,530 ✭✭✭User1998


    Benimar wrote: »
    The aim (not a guarantee!) is for 80% of adults to have had ONE dose by the end of June (2 months before EP).

    EP is pie in the sky to be honest. Vaccinated or not, any test events for large crowds will be matches and seated concerts, not uncontrolled crowds (in the sense of moving around) in what’s not necessarily being the most sanitary environment in the past.

    Regardless of it being two months or two weeks, we know one dose of the vaccine is very effective, and surely 2 months after June a lot more people will have gotten their second dose. I’m not saying I think EP will go ahead but IMO there is no reason to delay going back to a normal life after mid July never mind September (all dependent on vaccine supply of course)


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  • #2917
    funnydoggy
    Registered Users, Registered Users 2 Posts: 2,065 ✭✭✭funnydoggy


    User1998 wrote: »
    Regardless of it being two months or two weeks, we know one dose of the vaccine is very effective, and surely 2 months after June a lot more people will have gotten their second dose. I’m not saying I think EP will go ahead but IMO there is no reason to delay going back to a normal life after mid July never mind September (all dependent on vaccine supply of course)


    If we do have a good vaccination profile across the country, it would be an absolute shame not to have something like EP go ahead.


    At some stage, people will need to do their own risk analysis and act accordingly. It can't be up to NPHET et al, as they will be gone or out of the limelight soon.


  • #2918
    Derek Zoolander
    Registered Users, Registered Users 2 Posts: 434 ✭✭Derek Zoolander


    podgeandrodge wrote: »
    https://www.rte.ie/news/world/2021/0402/1207578-britain-vaccine-clots/

    Good article on differences in this article for FT subscribers

    Basically Europe used AZ on younger population where these conditions could be more regular - U.K. seen some instances but none with the secondary low platelets which is where it can be fatal..

    In short there is an increase in instances likely because of vaccines but still incredibly rare - in Germany it was 1 in 600k

    https://www.ft.com/content/d5cd63c6-af01-4d29-a5e5-b69ade4f3803


  • #2919
    Banana Republic 1
    Registered Users, Registered Users 2 Posts: 3,316 ✭✭✭Banana Republic 1


    Sobit1964 wrote: »
    Off hand do you know if it is detected by the anal swab that the chinese are using?

    Genetic tests I think

    https://www.reuters.com/article/us-health-coronavirus-france-variant-idUSKBN2B80GQ


  • #2920
    [Deleted User]
    Posts: 5,121 ✭✭✭ [Deleted User]


    Banana Republic 1 wrote: »
    Genetic tests I think

    https://www.reuters.com/article/us-health-coronavirus-france-variant-idUSKBN2B80GQ

    Woooosh!


  • #2921
    seamus
    Registered Users, Registered Users 2 Posts: 68,173 ✭✭✭✭seamus


    Vicxas wrote: »
    Do hospitals discharge on a public holiday? Or will we see a steady climb of hospitalisations over the weekend again
    We've seen a good chunk of discharges this week and I think a lot of that is down to, "Let's get you home for Easter" discharges.

    Today isn't a public holiday, so I expect we will see a good tranche of people discharged today too, and very few then until Tuesday. So we could be back to ~300 in hospital come Tuesday, but then it should drop again.


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  • #2922
    funnydoggy
    Registered Users, Registered Users 2 Posts: 2,065 ✭✭✭funnydoggy


    Banana Republic 1 wrote: »
    France has discovered a variant that can’t be picked up by current pcr test.




    Just to bring this up again, there was a short thread on r/COVID19 about it - - https://www.reddit.com/r/COVID19/comments/m9netk/sarscov2_variants_of_concern_are_associated_with/


    Doesn't seem to be what the headlines are saying.


  • #2923
    seamus
    Registered Users, Registered Users 2 Posts: 68,173 ✭✭✭✭seamus


    funnydoggy wrote: »
    Just to bring this up again, there was a short thread on r/COVID19 about it - - https://www.reddit.com/r/COVID19/comments/m9netk/sarscov2_variants_of_concern_are_associated_with/


    Doesn't seem to be what the headlines are saying.
    Indeed, they seem to be saying the exact opposite; newer variants appear to be *easier* to detect.

    This would indicate on average a higher viral load. Hard to say if this is down to the variants, or the nature of these samples having been taken mid-wave; average viral load may have been higher as the infection was significantly more prevalent in the community.

    Could also be a result of improvements in testing or swabbing.

    But this is why the media aren't saying anything about it; it's not of any real interest to the layman.


  • #2924
    Benimar
    Registered Users, Registered Users 2 Posts: 7,793 ✭✭✭Benimar


    User1998 wrote: »
    Regardless of it being two months or two weeks, we know one dose of the vaccine is very effective, and surely 2 months after June a lot more people will have gotten their second dose. I’m not saying I think EP will go ahead but IMO there is no reason to delay going back to a normal life after mid July never mind September (all dependent on vaccine supply of course)

    We will be doing more things, and I even mentioned some - going to matches, sit down concerts etc. Even then it will need a large proportion of the population to be fully vaccinated, not just have one dose.

    The conversation was about EP and there isn’t a hope that EP gets sanctioned this year.


  • #2925
    Away With The Fairies
    Banned (with Prison Access) Posts: 4,077 ✭✭✭Away With The Fairies


    Banana Republic 1 wrote: »
    France has discovered a variant that can’t be picked up by current pcr test.

    Ah sure it's grand. I think freedom is more important than quarantining the diseased.


  • #2926
    normanoffside
    Registered Users, Registered Users 2 Posts: 10,234 ✭✭✭✭normanoffside


    seamus wrote: »
    We've seen a good chunk of discharges this week and I think a lot of that is down to, "Let's get you home for Easter" discharges.

    Today isn't a public holiday, so I expect we will see a good tranche of people discharged today too, and very few then until Tuesday. So we could be back to ~300 in hospital come Tuesday, but then it should drop again.

    It’ll be reported as a rise in hospitalisations with no context until Tuesday


  • #2927
    Sobit1964
    Registered Users, Registered Users 2 Posts: 550 ✭✭✭Sobit1964


    Away With The Fairies wrote: »
    Ah sure it's grand. I think freedom is more important than quarantining the diseased healthy.

    Fixed that for you.


  • #2928
    [Deleted User]
    Posts: 5,121 ✭✭✭ [Deleted User]


    Away With The Fairies wrote: »
    Ah sure it's grand. I think freedom is more important than quarantining the diseased.

    “The diseased”. Christ, is this the way people think!?


  • #2929
    hotmail.com
    Registered Users, Registered Users 2 Posts: 14,441 ✭✭✭✭hotmail.com


    Sinn Fein support compassionate excemptions for travellers incoming to the country.

    The forced quarantine is about to collapse.

    Good riddance as well.


  • #2930
    Banana Republic 1
    Registered Users, Registered Users 2 Posts: 3,316 ✭✭✭Banana Republic 1


    seamus wrote: »
    Indeed, they seem to be saying the exact opposite; newer variants appear to be *easier* to detect.

    This would indicate on average a higher viral load. Hard to say if this is down to the variants, or the nature of these samples having been taken mid-wave; average viral load may have been higher as the infection was significantly more prevalent in the community.

    Could also be a result of improvements in testing or swabbing.

    But this is why the media aren't saying anything about it; it's not of any real interest to the layman.

    Except that all the people it was found in where dead and they showed up as clear on a pcr test when they were alive.


  • #2931
    Banana Republic 1
    Registered Users, Registered Users 2 Posts: 3,316 ✭✭✭Banana Republic 1


    Away With The Fairies wrote: »
    Ah sure it's grand. I think freedom is more important than quarantining the diseased.

    The people who had it are dead


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  • #2932
    [Deleted User]
    Posts: 5,121 ✭✭✭ [Deleted User]


    hotmail.com wrote: »
    Sinn Fein support compassionate excemptions for travellers incoming to the country.

    The forced quarantine is about to collapse.

    Good riddance as well.

    Once you start exempting certain people there is no point to the whole thing


  • #2933
    hotmail.com
    Registered Users, Registered Users 2 Posts: 14,441 ✭✭✭✭hotmail.com


    Deleted User wrote: »
    Once you start exempting certain people there is no point to the whole thing

    Sinn Fein are a joke.

    The reality of forced quarantine is very concerning and cruel for the people involved.


  • #2934
    seamus
    Registered Users, Registered Users 2 Posts: 68,173 ✭✭✭✭seamus


    Banana Republic 1 wrote: »
    Except that all the people it was found in where dead and they showed up as clear on a pcr test when they were alive.
    Have you got a link to a reputable source?

    Any road, showing up clear on a PCR test one day, and dead from Covid a week later has been happening since the start of this.


  • #2935
    purplefields
    Registered Users, Registered Users 2 Posts: 301 ✭✭purplefields


    Deleted User wrote: »
    That's not really how evolution works. While the end result may be the same as what you've said, it doesn't evolve to do something. An evolutionary trait is simply a mistake that happens to be useful and sticks around. A mistake that beats a vaccine is still a mistake.

    How does evolution work?

    My understanding of it is that there are random mutations, and the successful ones survive and reproduce.

    In the case of the vaccinated individual who becomes infected, again there are mutations. The ones that successfully evade the vaccine go on to create the new variant. (In fact, there is an amplification effect which I won't go into) This is why the World's eyes are on Israel. The canary. (But not a real canary)

    How is my understanding incorrect?


  • #2936
    mightyreds
    Registered Users, Registered Users 2 Posts: 2,893 ✭✭✭mightyreds


    Deleted User wrote: »
    “The diseased”. Christ, is this the way people think!?

    Its modern day leprosy, my cousin caught it recently and people were crossing the road while I was walking by and rolling up their car windows if i passed in fear of catching something I didn't even have.


  • #2937
    seamus
    Registered Users, Registered Users 2 Posts: 68,173 ✭✭✭✭seamus


    purplefields wrote: »

    How does evolution work?

    My understanding of it is that there are random mutations, and the successful ones survive and reproduce.

    In the case of the vaccinated individual who becomes infected, again there are mutations. The ones that successfully evade the vaccine go on to create the new variant. (In fact, there is an amplification effect which I won't go into) This is why the World's eyes are on Israel. The canary. (But not a real canary)

    How is my understanding incorrect?
    Your understanding is simplified; it implies that a single mutation at random will create a new variant that can evade the immune system in a vaccinated individual.

    The reality is that any beneficial mutation may confer a small % benefit in resisting the immune system. But it will eventually succumb.

    The window then is during this period if the virus can manage to jump hosts. If so, it may go on to mutate further, become more resistant, jump hosts again.

    And so forth. It's the "jumping hosts" part that's key here. The more time it can resist annihilation, the more time it has to spread and mutate.

    If there is herd immunity through vaccination, the window to jump hosts is massively reduced, and thus the time available to mutate is massively reduced. Every new host is vaccinated and will still annihilate the slightly more resistant strain before it has a chance to mutate and jump hosts again.

    Without vaccination, new hosts are not vaccinated, and thus the window to mutate and spread is massive.

    Different viruses also have different mutation rates. Coronaviruses do not mutate at nearly the same rate as influenza. So comparisons with yearly 'flu vaccines are not valid.


  • #2938
    Banana Republic 1
    Registered Users, Registered Users 2 Posts: 3,316 ✭✭✭Banana Republic 1


    seamus wrote: »
    Have you got a link to a reputable source?

    Any road, showing up clear on a PCR test one day, and dead from Covid a week later has been happening since the start of this.

    I did go back to the original post you replied to they were also discussing it on Claire Burn. You
    yourself don’t post any source for what you say.


  • #2939
    purplefields
    Registered Users, Registered Users 2 Posts: 301 ✭✭purplefields


    seamus wrote: »
    Your understanding is simplified; it implies that a single mutation at random will create a new variant that can evade the immune system in a vaccinated individual.
    Different viruses also have different mutation rates. Coronaviruses do not mutate at nearly the same rate as influenza. So comparisons with yearly 'flu vaccines are not valid.

    I posted a simplifed version of it because of the nature of this thread. I don't believe I posted that a 'single mutation at random will create a new variant that can evade the immune system in a vaccinated individual' Although, is this possible? Afterall, the single Eeek mutation is found in more than one variant and is causing havoc.

    However, the basic premise is correct, is it not?

    Regarding comparison to other virus, it might me worth also noting that cv is a single strand RNA virus, so more likely to have mutations compared to DNA virus. Consider also how contagious it is. This is also a factor when analysing mutations. (More people infected = more scope for new variants)


  • #2940
    purplefields
    Registered Users, Registered Users 2 Posts: 301 ✭✭purplefields


    nocoverart wrote: »
    Funny how most posters with new accounts come across as miserable, scaremongering twats. Covid and its many “scariants” aren’t really the biggest concern now, bitter fooks who spread false information are.

    I'm guessing this is directed at me. I don't mind to be honest - It made me smile.
    You might have a point (In fact I hope you do!).


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  • #2941
    MerlinSouthDub
    Registered Users, Registered Users 2 Posts: 1,629 ✭✭✭MerlinSouthDub


    GP referral data is out for yesterday. The data is a bit noisy (small sample size) but referrals are down significantly compared to last week.

    Hope to see this trend continue

    https://tomorrowscare.ie/covid/2021-04-02_COVID_GP_Survey_Results.pdf


This discussion has been closed.
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