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What exactly is happening with AstraZeneca?

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Comments

  • Registered Users, Registered Users 2 Posts: 14,595 ✭✭✭✭CIARAN_BOYLE




  • Registered Users, Registered Users 2 Posts: 7,548 ✭✭✭Pete_Cavan


    AZ had to agree to selling the vaccine at cost because that was the price those who developed it imposed.

    Oxford left the door open for a margin to be made;

    https://innovation.ox.ac.uk/technologies-available/technology-licensing/expedited-access-covid-19-related-ip/
    The default approach of the University and OUI regarding (1) will be to offer non-exclusive, royalty-free licences to support free of charge, at-cost or cost + limited margin supply as appropriate, and only for the duration of the pandemic, as defined by the WHO

    AZ may well be making a margin on every doses, that may be why they signed up to supply so much of it - a small margin on a huge volume gives a good profit. Unfortunately for everyone, they can't produce nearly as much as they signed up to.


  • Registered Users, Registered Users 2 Posts: 13,023 ✭✭✭✭Joe_ Public


    Aegir wrote: »
    can you give me a list of the companies banging down the door wanting to produce this?

    Was never offered so how would anyone know? And what difference should it have made to AZ anyway? If they're not interested in profit, as we're being led to believe, why would they care about the vaccine being open source? The more, the merrier surely. And then, maybe poor countries like Uganda and Bangladesh wouldn't be paying more than rich western countries, even before you take GDP into account.


  • Registered Users, Registered Users 2 Posts: 7,548 ✭✭✭Pete_Cavan


    But no matter what they do they are the scum that lied to us about what they were going to give us.

    It has already been pointed out to you that Oxford were preveted from signing a contract with Merck

    https://www.boards.ie/vbulletin/showpost.php?p=116617508&postcount=3424


  • Posts: 5,853 ✭✭✭ [Deleted User]


    Was never offered so how would anyone know? And what difference should it have made to AZ anyway?

    offered where? an advert on donedeal maybe?

    this is just pure speculation.
    If they're not interested in profit, as we're being led to believe, why would they care about the vaccine being open source? The more, the merrier surely. And then, maybe poor countries like Uganda and Bangladesh wouldn't be paying more than rich western countries, even before you take GDP into account.

    They don't own the IP, just the licence so unless we know the details of that licensing agreement, none of us can say for sure.

    Uganda and Bangladesh aren't paying for the vaccine are they? isn't that what Covax is all about? Do you have something that shows what Covax is paying?


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  • Registered Users, Registered Users 2 Posts: 13,023 ✭✭✭✭Joe_ Public


    Pete_Cavan wrote: »
    Oxford left the door open for a margin to be made;

    https://innovation.ox.ac.uk/technologies-available/technology-licensing/expedited-access-covid-19-related-ip/



    AZ may well be making a margin on every doses, that may be why they signed up to supply so much of it - a small margin on a huge volume gives a good profit. Unfortunately for everyone, they can't produce nearly as much as they signed up to.

    I dont have an issue with AZ making a profit at all btw, would be rather strange if they weren't in it to make money after all. Just this not for profit line gets thrown out willy nilly, as if they're acting as some sort of benevolent white knights, only in it to save the whole world.

    According to a mou they signed in brazil last year, 1 july has been set as a date the pandemic can be declared over. At least with this particular deal anyway.

    https://www.ft.com/content/c474f9e1-8807-4e57-9c79-6f4af145b686


  • Registered Users, Registered Users 2 Posts: 13,023 ✭✭✭✭Joe_ Public


    Aegir wrote: »
    offered where? an advert on donedeal maybe?

    this is just pure speculation.



    They don't own the IP, just the licence so unless we know the details of that licensing agreement, none of us can say for sure.

    Uganda and Bangladesh aren't paying for the vaccine are they? isn't that what Covax is all about? Do you have something that shows what Covax is paying?

    Uganda paid $7 per dose for an order of 18m. Bangladesh was a little cheaper, but still around twice the price of the uk or eu. South Africa paid over the top two, but they dont want to use it anyway i dont think so....

    Covax is fine, beautiful concept, but do you think that's going to save the world? Reality is while the us and uk talks about vaccinating the world, while continuing to hoard stock, it is actually the chinese, and to a much lesser extent, the Russians who are out there doing it. Not simply talking about it.

    https://healthpolicy-watch.news/uganda-defends-astrazeneca-price-says-its-not-higher-than-other-countries/


  • Posts: 5,853 ✭✭✭ [Deleted User]


    Pete_Cavan wrote: »
    It has already been pointed out to you that Oxford were preveted from signing a contract with Merck

    https://www.boards.ie/vbulletin/showpost.php?p=116617508&postcount=3424


    That article is a bit tabloidy. The WSJ have a far better analysis here https://www.wsj.com/articles/oxford-developed-covid-vaccine-then-scholars-clashed-over-money-11603300412

    it's behind a paywall though.

    In short, Oxford wanted to ensure two things, firstly that they did not give yet another drug to the world that they received nothing from, but a pharma giant would make a **** load of money from. secondly, that it would be offered to all countries on an even basis

    Uganda paid $7 per dose for an order of 18m. Bangladesh was a little cheaper, but still around twice the price of the uk or eu. South Africa paid over the top two, but they dont want to use it anyway i dont think so....

    Covax is fine, beautiful concept, but do you think that's going to save the world? Reality is while the us and uk talks about vaccinating the world, while continuing to hoard stock, it is actually the chinese, and to a much lesser extent, the Russians who are out there doing it. Not simply talking about it.

    https://healthpolicy-watch.news/uganda-defends-astrazeneca-price-says-its-not-higher-than-other-countries/

    it's like the Health minister said, you can't compare shipping millions of doses from a factory in Germany to a distribution hub in Dublin. There may be distribution considerations there that don't apply in europe.

    They are on the face of it paying three times what the EU is, but it is sill less than a third of the Pfizer vaccine.


  • Registered Users, Registered Users 2 Posts: 5,518 ✭✭✭fly_agaric


    Aegir wrote: »
    One customer is taking the approach of setting up suitable manufacturing facilities and ensuring they work, the other is bunging a wad of upfront cash at them and saying "sort it out". Which approach is the most likely to work?

    Fair dues to the British, but it has not really worked out completely for them. Alot of recent content on the thread would be irrelevant if it had would it not?

    (If media stories are correct), I suppose even if UK will be seeking to import multi-millions of doses from any AZ EU-located stockpile, it will still be insignificant in context of the hundreds of millions of missing vaccine doses AZ will end up stiffing the EU for.

    Whatever the UKs clever contracts with the benevolent MNC contain it all seems a bit, well Irish, to me!:pac:


  • Registered Users, Registered Users 2 Posts: 6,700 ✭✭✭Wolf359f


    Aegir wrote: »

    Are they all not supplied from SII?
    SII was granted a licence to produce 1bil doses of the Oxford vaccine. I'm not sure if the licence came from AZ or Oxford, but AZ thankfully don't seem to have any part in SII.

    The issues with the Oxford vaccine in the EU is solely down to AZ, not Oxford or SII.


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  • Registered Users, Registered Users 2 Posts: 269 ✭✭deeperlearning


    AstraZeneca have run into problems in the US.

    U.S. health officials question results from AstraZeneca’s vaccine trial, less than a day after they’re released.

    https://www.nytimes.com/live/2021/03/23/world/covid-vaccine-coronavirus-cases#us-health-officials-question-results-from-astrazenecas-vaccine-trial-less-than-a-day-after-theyre-released


    This could spell serious trouble.


  • Registered Users, Registered Users 2 Posts: 5,518 ✭✭✭fly_agaric


    Wolf359f wrote: »
    Are they all not supplied from SII?
    SII was granted a licence to produce 1bil doses of the Oxford vaccine. I'm not sure if the licence came from AZ or Oxford, but AZ thankfully don't seem to have any part in SII.

    The issues with the Oxford vaccine in the EU is solely down to AZ, not Oxford or SII.

    Another poster (Danzy) is claiming the UK (along with the US) will be "vaccinating the whole world". The Raj never ended.


  • Posts: 45,738 ✭✭✭✭ [Deleted User]


    AstraZeneca have run into problems in the US.

    U.S. health officials question results from AstraZeneca’s vaccine trial, less than a day after they’re released.

    https://www.nytimes.com/live/2021/03/23/world/covid-vaccine-coronavirus-cases#us-health-officials-question-results-from-astrazenecas-vaccine-trial-less-than-a-day-after-theyre-released


    This could spell serious trouble.


    J&J walking in like a boss

    tenor.gif


  • Registered Users, Registered Users 2 Posts: 14,595 ✭✭✭✭CIARAN_BOYLE


    Pete_Cavan wrote: »
    It has already been pointed out to you that Oxford were preveted from signing a contract with Merck

    https://www.boards.ie/vbulletin/showpost.php?p=116617508&postcount=3424

    I don't see what that has to do with AstraZeneca doing a deal with the EU and not meeting it.


  • Registered Users, Registered Users 2 Posts: 7,548 ✭✭✭Pete_Cavan


    I don't see what that has to do with AstraZeneca doing a deal with the EU and not meeting it.

    Just pointing out that AZ were not the only company interesting in working with Oxford to produce their vaccine. Some would have us believe that AZ were the only company interested.

    Perhaps if Oxfords vision of an open source vaccine had been realised, the vaccine may have been produced on a bigger scale and the errors with trials and applications may not have occurred, although that is obviously speculation. Instead we are stuck with AZ.


  • Registered Users, Registered Users 2 Posts: 5,905 ✭✭✭dogbert27


    US health chiefs accuse AstraZeneca of providing out dated information

    https://www.dailymail.co.uk/news/article-9391951/AstraZeneca-accused-providing-outdated-information-vaccine-trial.html

    I wonder will the UK government and media attack the US as vehemently as they have attacked EU countries who raised concerns?


  • Registered Users, Registered Users 2 Posts: 1,123 ✭✭✭mick087


    Seeing how AZ efficacy keeps going down, questions in us and the blood clot saga, Boris’ campaign to semi “vaccinate” the UK population might yet go into history books for a giant placebo experiment or worse

    Step aside please.
    The more foolish people like you there are then the quicker i move up the queue in getting this vaccine.


  • Registered Users, Registered Users 2 Posts: 7,548 ✭✭✭Pete_Cavan


    dogbert27 wrote: »
    I wonder will the UK government and media attack the US as vehemently as they have attacked EU countries who raised concerns?

    Given how vehemently the UK media has attacked the EU for potentially blocking exports of vaccines while saying very little about India actively blocking export of vaccines to them, I doubt it.


  • Registered Users, Registered Users 2 Posts: 21,722 ✭✭✭✭Strazdas


    mick087 wrote: »
    Step aside please.
    The more foolish people like you there are then the quicker i move up the queue in getting this vaccine.

    My own view is that I don't trust AZ as a company but I would have no problem at all taking their vaccine. I think the management are a bit dodgy but I don't see an issue with the vaccine itself (bar the tiny risk of blood clots etc).


  • Registered Users, Registered Users 2 Posts: 1,123 ✭✭✭mick087


    Oh please stop sneering I ain’t an anti vaxer and want get vaccinated ASAP

    The AZ vaccine keeps hitting problems that others are not, like the Russian vaccine there’s way to much politics, little science (as per Americans who had no issues approving other vaccines) and loads of smoke from what seems to be a dumpster fire operation.

    No not sneering if you dont wish to take it that is grand.

    Like i say the more folks like you there are then the quicker i move up the queue in getting the vaccine.


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  • Registered Users, Registered Users 2 Posts: 7,548 ✭✭✭Pete_Cavan


    mick087 wrote: »
    No not sneering if you dont wish to take it that is grand.

    Like i say the more folks like you there are then the quicker i move up the queue in getting the vaccine.

    The issue most people have is not fear of taking an AZ produced vaccine, its that we may never get the chance to take an AZ produced vaccine given how bad their performance has been.


  • Registered Users, Registered Users 2 Posts: 1,123 ✭✭✭mick087


    Strazdas wrote: »
    My own view is that I don't trust AZ as a company but I would have no problem at all taking their vaccine. I think the management are a bit dodgy but I don't see an issue with the vaccine itself (bar the tiny risk of blood clots etc).

    Look over the pond, there is all the evidence you need to see if this vaccine works.

    If you don't wish to take it then that is ok.

    But let the right people know when your turn comes to taking it that don't wish to take this vaccine.
    This could and will save time and allow those who do wish to take it take it.


  • Registered Users, Registered Users 2 Posts: 19,088 ✭✭✭✭BonnieSituation


    mick087 wrote: »
    Look over the pond, there is all the evidence you need to see if this vaccine works.

    If you don't wish to take it then that is ok.

    But let the right people know when your turn comes to taking it that don't wish to take this vaccine.
    This could and will save time and allow those who do wish to take it take it.

    I got my AZ vaccine yesterday. (Last night was hell. God bless paracetamol.)

    I think AZ are shysters.

    They're not mutually exclusive options/opinions.


  • Registered Users, Registered Users 2 Posts: 1,123 ✭✭✭mick087


    Even if the vaccine you are taking is not much better than a placebo ?

    A dodgy vaccine would be terrible for the vaccination drive and cause hesitation in public. Like I said AZ thing is like a dumpster fire compared to rest

    Macron gets your vote then.
    Just move out of line for this vaccine then would you.


  • Registered Users, Registered Users 2 Posts: 1,123 ✭✭✭mick087


    Pete_Cavan wrote: »
    The issue most people have is not fear of taking an AZ produced vaccine, its that we may never get the chance to take an AZ produced vaccine given how bad their performance has been.

    But you would if you get the chance take it yes?

    I would.


  • Registered Users, Registered Users 2 Posts: 7,548 ✭✭✭Pete_Cavan


    mick087 wrote: »
    Look over the pond, there is all the evidence you need to see if this vaccine works.

    If you don't wish to take it then that is ok.

    But let the right people know when your turn comes to taking it that don't wish to take this vaccine.
    This could and will save time and allow those who do wish to take it take it.

    Presenting people unhappy with AZs performance as people unwilling to take an AZ vaccine is disingenuous at best, trolling at worse.


  • Registered Users, Registered Users 2 Posts: 1,123 ✭✭✭mick087


    I got my AZ vaccine yesterday. (Last night was hell. God bless paracetamol.)

    I think AZ are shysters.

    They're not mutually exclusive options/opinions.

    Lucky you.

    If i had of gotten this jab I would not be criticizing the jab that might well save me from death

    Your very lucky you have gotten the jab.


  • Registered Users, Registered Users 2 Posts: 23,246 ✭✭✭✭Dyr


    Pete_Cavan wrote: »

    The EMA application for Sputnik was only made recently and no Chinese application yet, nothing the EU can do about this. Any application is considered, your claim that the EU wouldnt consider for approval for political reasons is a barefaced lie. Individual countries can approve them themselves if they wish, as some have which you pointed out, so no big bad EU preventing it.


    Bare faced lie, eh?


    EU has ‘absolutely no need’ of Sputnik V vaccine, commissioner says

    https://www.euractiv.com/section/global-europe/news/eu-has-absolutely-no-need-of-sputnik-v-vaccine-commissioner-says/


    It's fairly obvious the EU has dragging its heels on approving Sputnik for entirely political reasons, just as the Russians are offering it to them for entirely political reasons.

    Of course, if the EUs vaccine rollout wasnt a complete shambles the Russians would have no angle to embarass them. Meanwhile its us lot who get shafted while the poor craturs on here have to make excuses for their betters in Brussels

    Speaking of Brussels, hows that dispute resolution mechanism against AZ coming along? Still under consideration, along wth blocking exports? The Commision are fairly slow with that front too, almost like they know they havent got a leg to stand on :o

    Still, its election year in Germany so I'm sure the bould Ursula will have her eye on that while making decisions for the entire continent


  • Registered Users, Registered Users 2 Posts: 23,246 ✭✭✭✭Dyr


    I got my AZ vaccine yesterday. (Last night was hell. God bless paracetamol.)

    I think AZ are shysters.

    They're not mutually exclusive options/opinions.

    If you don't mind answering a personal question, what tier are you in?


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  • Registered Users, Registered Users 2 Posts: 1,123 ✭✭✭mick087


    I am in the back of the line don’t worry

    It’s the people who are going to refuse take ANY vaccines because of how unprofessional AZ are that concerns me

    Btw you really need to work on your reading comprehension and not tar people as anti vaccines, where there is smoke there is usually a fire

    Good man your doing your bit to save lives by going to the back of the queue.
    But could you also keep it down a bit your scaring some of the others.


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