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COVID-19: Vaccine and testing procedures Megathread Part 3 - Read OP

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  • Posts: 10,049 ✭✭✭✭ [Deleted User]


    We aren't overly concerned , she thought it would have eased if anything if sorer now than a few days ago

    It’s a needle directly into the muscle. Of course it can be sore for days. Possibly caught a nerve


  • Closed Accounts Posts: 309 ✭✭Dressoutlet


    I visited my Nans grave today, she died of Covid in a nursing home last May. I've never been one to go the graveyard, but because I couldn't attend her funeral I feel terrible guilty. So I go up a lot and I feel better. She was over 95, no comorbities. She would likely have had her 2 vaccines now. Not really much point to this, but I hate that she was taken. I hate we didn't get to see her before she died. I hate she didn't get the party she deserved


  • Registered Users, Registered Users 2 Posts: 15,068 ✭✭✭✭Danzy


    I visited my Nans grave today, she died of Covid in a nursing home last May. I've never been one to go the graveyard, but because I couldn't attend her funeral I feel terrible guilty. So I go up a lot and I feel better. She was over 95, no comorbities. She would likely have had her 2 vaccines now. Not really much point to this, but I hate that she was taken. I hate we didn't get to see her before she died. I hate she didn't get the party she deserved

    You are doing right by her and paying your respects. You are playing a desperate hand in the only way you can and making the best of the situation.

    That's good to see. My condolences to you.


  • Registered Users, Registered Users 2 Posts: 54 ✭✭tosspot




  • Registered Users, Registered Users 2 Posts: 3,815 ✭✭✭snotboogie


    seamus wrote: »
    I'd say we can expect 900,000 done by the end of the month, if not more. We'll hit the 1m mark in early April and 2m a month later.

    250k vaccines between the 18th and 31st of March seems extraordinary. That's 20k vaccines a day and a nearly 40% increase in our total vaccinations in 13 days. It also puts us at an average of 0.4 vaccines per 100 people per day for 13 days when we have struggled to maintain anything above a 0.2 for any length of time.

    Not having a pop at you BTW, appreciate your answer. Just wanted to share some of my concerns. If we reach 900k by the end of the month the ramp up will be now. Vaccine figures will be fascinating over the next two weeks.


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  • Registered Users, Registered Users 2 Posts: 15,068 ✭✭✭✭Danzy


    snotboogie wrote: »
    250k vaccines between the 18th and 31st of March seems extraordinary. That's 20k vaccines a day and a nearly 40% increase in our total vaccinations in 13 days. It also puts us at an average of 0.4 vaccines per 100 people per day for 13 days when we have struggled to maintain anything above a 0.2 for any length of time.

    Not having a pop at you BTW, appreciate your answer. Just wanted to share some of my concerns. If we reach 900k by the end of the month the ramp up will be now. Vaccine figures will be fascinating over the next two weeks.

    It's a lot but it is still only about the normal flu season vaccination rate.

    Very doable if it comes in. Thankfully.


  • Registered Users, Registered Users 2 Posts: 1,929 ✭✭✭Marhay70


    snotboogie wrote: »
    250k vaccines between the 18th and 31st of March seems extraordinary. That's 20k vaccines a day and a nearly 40% increase in our total vaccinations in 13 days. It also puts us at an average of 0.4 vaccines per 100 people per day for 13 days when we have struggled to maintain anything above a 0.2 for any length of time.

    Not having a pop at you BTW, appreciate your answer. Just wanted to share some of my concerns. If we reach 900k by the end of the month the ramp up will be now. Vaccine figures will be fascinating over the next two weeks.

    I suppose in reality we have to be grateful it's the HSE that's in charge of the roll out. I never thought I'd say that but when you see the fcukwittery that is emanating from political circles all over the world, it's good to have at least a few competent souls we can depend on.


  • Registered Users, Registered Users 2 Posts: 11,787 ✭✭✭✭ACitizenErased


    I don't usually post things from Reddit but there was some fairly significant vaccine analysis posted on r/Ireland tonight with sources. Fair play to u/bubble831 for this.

    Why the vaccination situation isn't as bad as it seems [Long post]
    TLDR; Over 70s should be finished with one dose by the end of the week beginning the 12th of April. 65-69 should begin getting theirs either that week or the week before. Serious at risk group will all have their first vaccinations by the week ending the 11th of April. Government should have enough vaccines for 86% of our population to be fully vaccinated by the end of June thus the 80% with a first dose looks very realistic.

    There’s been a lot of talk recently about how people don’t believe that the vaccination process is going to be ramped up and people confused about when they will have an opportunity to be vaccinated. I wanted to set a few things straight and perhaps convince people that things aren’t as bad as they might think.

    Firstly, the boring stuff (warning, the whole post is quite boring). All my information comes directly from government data. I will be using a combination of the original Irish delivery schedule (a month outdated) as well as the Swedish vaccine schedule (linked below, updated weekly) as my sources. I will obviously adjust the Swedish figures for our population (divided by 2.08). I will also be using data from the Danish scheduler to try and pinpoint potential weekly deliveries in March and April. I will not be using the Danish data to find out how many doses Ireland will receive as it is well known that Denmark gets a higher per capita amount of vaccines than Ireland and other EU countries (that’s a story for another day). I am also going to assume that we continue to administer pretty much all vaccines we get on a particular week (eg week 1) on the following week (eg week 2). This is fairly consistent with the evidence we have so far (for example we received 93k vaccines on the week beginning the 1st of March and administered roughly 92k vaccines on the week starting the 8th of March)

    So, thus far we received 758k vaccines up to last Sunday. In December we had 40k vaccines delivered. In January we had 166k. In February we saw 312k. In the first two weeks of March we received 238k (compared to 143k in the first two weeks of Feb). We received 144,840 vaccines in the week starting the 8th of March. The highest before that was 94,620 in the week beginning the 15th of Feb and 93,330 for the week beginning the 1st of March. This is clear evidence of a ramp up and this will continue to get better. We are due 1.1 million vaccines by the end of March, this target is consistent with Swedish vaccine figures which are updated weekly (every Friday). This means 342k in the last 2.5 weeks of the quarter, and average of 136,800 per week. But we are due 40k extra Pfizer due to a deal agreed last week with the EU so we are actually due something around 1.14 million in the quarter. Now, Paul Reid said today we got around 10k AZ this week. This is consistent with the Danes expecting around 14k. They expect this amount again next week (week starting the 22nd) with the vast majority of AZ coming in the last week (beginning 29th) and thus this would be administered on the week beginning the 5th of April. Moderna still owe us 60k vaccines this quarter also. We have been told to expect it towards the end of the month. Judging by the Danish vaccine schedule we would be due this the week beginning the 22nd. Anyway I’m rambling through my points now, but you get the idea. Thus, below is the estimated vaccine administration for up to the end of April, basically estimated deliveries plus one week. For Moderna, half the doses delivered are kept back for second doses, while Pfizer and AZ are pretty much all given out.

    Week 10 (completed already) : 617k

    Week 11 (beginning 15th of March) : 60k (all Pfizer due to AZ cancelation) = 677k

    Week 12 (22nd March) : 165k (75k Pfizer + 90k AZ, consisting of 80k in fridges due to pause and 10k deliveries) = 842k

    Week 13 (29th March) : 125k (75K Pfizer + 30k Moderna + 10k AZ) = 967k

    Week 14 (5th April) : 175k (75k Pfizer + 100k AZ) = 1.142 million

    Week 15 (12th April) : 192k (140k Pfizer + 10k Moderna + 42k AZ) = 1.334 million

    Week 16 (19th April) : 180k (140k Pfizer + 40k AZ) = 1.514 million

    Week 17 (26th April) : 263k (140k Pfizer + 50k Moderna [20k first dose, 30k second dose] + 73k AZ) = 1.777 million

    Week 18 (3rd May) : 349k (140k Pfizer + 209k AZ) = 2.126 million

    Note that this does not include J&J deliveries in April which are projected to be around 100k. This gets us to 2.226 million vaccines delivered by the end of April. Per capita, by the Swedish vaccine schedule we should have 2.235 million, so this is roughly correct in terms of what each week should look like (especially when you add in the 20k Moderna doses that have been administered as first doses and will be slowly given out as second doses in the coming 4 weeks)

    Now, what does that mean for each cohort? Well, I’m going to assume, other than second doses, cohorts 1 and 2 are finished (which is pretty much correct). Per the links below there are around 500k people over 70 and 700k people over 65 (thus 200k 65-69). There are 140k-150k people in cohort 4 (no source on this I just read it was around that number, feel free to correct). The 65-69 age cohort are due the AZ after the serious at risk group. Only 5k of these have been done so basically the next 150k AZ will be given to them.

    This puts the 65-69 group starting on the week of the 5th of April or the week starting the 12th of April.

    There are roughly 350k doses of mRNA vaccines that need to be given as second doses before the 18th of April. There are around 150k over 70s with one dose so this leaves around 350k yet to get a dose. This would have all over 70s getting a dose by the end of the week beginning the 12th of April (again this is consistent with the governments promise of all over 70s getting a jab by mid-April).

    Cohorts 6 (which is small enough) and cohort 7 should thus begin somewhere around the 19th of April, if not the week earlier.

    Again this is all kind of confusing but the general point is we have vaccines coming, and the programme will significantly ramp up in the coming weeks. By the end of June we should have somewhere around 5.25 million 2 dose vaccines and 600k J&J (not including CureVac approval). This is enough to fully vaccinate 3.225 million people or 86% of the adult population. This includes 1.2 million AZ. If you exclude AZ (unreliable), we would still have enough to fully vaccinate 70% of our population by the end of Q2 (again, add at least a week for the vaccines to be administered)

    Irish delivery schedule (published in February) https://www.gov.ie/en/publication/c4876-covid-19-resilience-and-recovery-2021-the-path-ahead/

    Original vaccine schedule post https://www.reddit.com/r/ireland/comments/lr9t5o/vaccinations_in_ireland_as_of_21022021_total/gokiqll/

    Swedish vaccination schedule (Deliveries): https://www.folkhalsomyndigheten.se/smittskydd-beredskap/utbrott/aktuella-utbrott/covid-19/statistik-och-analyser/prognos-av-vaccinleveranser/

    Danish vaccination calendar: https://www.sst.dk/-/media/Udgivelser/2021/Corona/Vaccination/Kalender/Specificeret-vaccinationskalender-19032021.ashx?la=da&hash=DFDFB441004E2C313ED7724FCE2018DF26650DC9

    Irish week 9 and 10 deliveries: https://twitter[dot]com/newschambers/status/1372150312316833798

    Irish first two months deliveries: https://twitter[dot]com/FergalBowers/status/1367521128646852609/photo/1

    Estimated over 70s breakdown: https://twitter[dot]com/FergalBowers/status/1366026746127130629

    Ireland population demographics: https://www.cso.ie/en/releasesandpublications/ep/p-cp7md/p7md/p7dgs/
    https://www.reddit.com/r/ireland/comments/ma2y3h/why_the_vaccination_situation_isnt_as_bad_as_it/


  • Registered Users, Registered Users 2 Posts: 10,462 ✭✭✭✭WoollyRedHat


    tosspot wrote: »

    Good news in that article it states that internal AstraZeneca document shared with Reuters suggests the company expects EU approval for their Halix plant by March 25th.


  • Registered Users, Registered Users 2 Posts: 1,820 ✭✭✭larchielads


    When are we due j&j vaccine into the country ?


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  • Registered Users, Registered Users 2 Posts: 6,567 ✭✭✭Wolf359f


    When are we due j&j vaccine into the country ?

    Second half of April I believe.


  • Registered Users, Registered Users 2 Posts: 12,523 ✭✭✭✭Red Silurian


    I don't usually post things from Reddit but there was some fairly significant vaccine analysis posted on r/Ireland tonight with sources. Fair play to u/bubble831 for this.

    Why the vaccination situation isn't as bad as it seems [Long post]


    https://www.reddit.com/r/ireland/comments/ma2y3h/why_the_vaccination_situation_isnt_as_bad_as_it/

    These figures are fantastic, if true, but the govt have said they'll be administering 1.3m doses in the months of April, May and June and by the looks of your post they'll only be getting 935k between weeks 13-17


  • Registered Users, Registered Users 2 Posts: 12,000 ✭✭✭✭scudzilla


    Supposedly my group, age 18-69 who are at very high risk, are being vaccinated, i spoke to my doctor surgery but they've said no, where should i contact now??


  • Registered Users, Registered Users 2 Posts: 6,567 ✭✭✭Wolf359f


    These figures are fantastic, if true, but the govt have said they'll be administering 1.3m doses in the months of April, May and June and by the looks of your post they'll only be getting 935k between weeks 13-17

    That does exclude J&J from April onwards and also Curevac from (possibly) June onwards. But I don't believe our Governments timetable included Curevac at all.


  • Registered Users, Registered Users 2 Posts: 2,027 ✭✭✭lbj666


    I don't usually post things from Reddit but there was some fairly significant vaccine analysis posted on r/Ireland tonight with sources. Fair play to u/bubble831 for this.

    Why the vaccination situation isn't as bad as it seems [Long post]


    https://www.reddit.com/r/ireland/comments/ma2y3h/why_the_vaccination_situation_isnt_as_bad_as_it/

    Its worth mentioning that even if the hoped target isn't met by June and there is slippage, that slippage should be recovered quiet fast in July with J&J at full speed for a 2nd month, AZ hopefully getting things ironed out, UK/USA closer finishing before EU with Curevac, Novavax and sputnick even coming on board.

    Think exponential graphs but in a good way.


  • Registered Users, Registered Users 2 Posts: 12,523 ✭✭✭✭Red Silurian


    Wolf359f wrote: »
    That does exclude J&J from April onwards and also Curevac from (possibly) June onwards. But I don't believe our Governments timetable included Curevac at all.

    Fair point, I think 100k AstraZenneca in week 14 and 200k in week 18 could be hopeful as well but I'll reserve judgement until nearer the date


  • Registered Users, Registered Users 2 Posts: 883 ✭✭✭eoinbn


    Wolf359f wrote: »
    That does exclude J&J from April onwards and also Curevac from (possibly) June onwards. But I don't believe our Governments timetable included Curevac at all.

    Curevac is Q3 and small numbers if/when it happens. Not going to be a factor.


  • Registered Users, Registered Users 2 Posts: 6,628 ✭✭✭Micky 32




  • Registered Users, Registered Users 2 Posts: 6,567 ✭✭✭Wolf359f


    eoinbn wrote: »
    Curevac is Q3 and small numbers if/when it happens. Not going to be a factor.

    Sweden may need to update their forecast so.
    https://www.folkhalsomyndigheten.se/smittskydd-beredskap/utbrott/aktuella-utbrott/covid-19/statistik-och-analyser/prognos-av-vaccinleveranser/
    They could be just being super optimistic though.


  • Registered Users, Registered Users 2 Posts: 883 ✭✭✭eoinbn


    Wolf359f wrote: »

    Curevac were hoping to get approval in may but recent P3 results have variants data so requires further analysis. They are aiming for the end of the quarter now.
    Wacker are hoping to start production soon with first doses arriving in July.
    If the EU had a clue it would be funding early production of vaccine rather than just hoping for a miracle with AZ.


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  • Registered Users, Registered Users 2 Posts: 6,567 ✭✭✭Wolf359f


    eoinbn wrote: »
    Curevac were hoping to get approval in may but recent P3 results have variants data so requires further analysis. They are aiming for the end of the quarter now.
    Wacker are hoping to start production soon with first doses arriving in July.
    If the EU had a clue it would be funding early production of vaccine rather than just hoping for a miracle with AZ.

    I don't think they are expecting much from AZ tbh.
    Looking there, Curevac expect 50mil doses by year end.
    Guess it's not a runner so.


  • Moderators, Science, Health & Environment Moderators Posts: 14,709 Mod ✭✭✭✭marno21


    Further to ACE's excellent post sourced from Reddit above, the current delivery schedules given us 106.5 doses per 100 people of the 2 dose vaccines plus another 600k J&J vaccines, which if compared to the 2 dose vaccines, would allow us to have 131 doses per 100 people (counting J&J's vaccines as 2 doses for this exercise).

    Israel are currently at 111 per 100 people. Israel opened a few weeks ago and cases continue to drop, even though they were going through a heavy wave during the initial weeks of vaccination. The R0 there is 0.7 and dropping, and deaths and hospitalisations have fallen off a cliff.

    I have little doubt that come July we will be worlds apart from where we are now. What annoys me is that there is fcuk all effort being made to communicate this and cases are rising in Ireland again because the public are fed up with 18 weeks of glorified house arrest over the last 21 weeks


  • Registered Users, Registered Users 2 Posts: 2,354 ✭✭✭nocoverart


    Variant is now a word i detest! right up there with fatty, ginger or ugly. Then again, if you have all of the above Covid is probably your best bet :)


  • Registered Users, Registered Users 2 Posts: 883 ✭✭✭eoinbn


    marno21 wrote: »
    Further to ACE's excellent post sourced from Reddit above, the current delivery schedules given us 106.5 doses per 100 people of the 2 dose vaccines plus another 600k J&J vaccines, which if compared to the 2 dose vaccines, would allow us to have 131 doses per 100 people (counting J&J's vaccines as 2 doses for this exercise).

    Israel are currently at 111 per 100 people. Israel opened a few weeks ago and cases continue to drop, even though they were going through a heavy wave during the initial weeks of vaccination. The R0 there is 0.7 and dropping, and deaths and hospitalisations have fallen off a cliff.

    I have little doubt that come July we will be worlds apart from where we are now. What annoys me is that there is fcuk all effort being made to communicate this and cases are rising in Ireland again because the public are fed up with 18 weeks of glorified house arrest over the last 21 weeks

    I am trying to stop false optimism here.
    The Reddit figures are based on bad data. We know the Irish government figures are nonsense. We knew that on the day they published them. The Reddit figures are also including Curevac, which won't happen, and Novavax which is becoming less and less likely.
    Things are moving in the right direction but it will be a long slow slog.


  • Registered Users, Registered Users 2 Posts: 6,567 ✭✭✭Wolf359f


    eoinbn wrote: »
    I am trying to stop false optimism here.
    The Reddit figures are based on bad data. We know the Irish government figures are nonsense. We knew that on the day they published them. The Reddit figures are also including Curevac, which won't happen, and Novavax which is becoming less and less likely.
    Things are moving in the right direction but it will be a long slow slog.

    Reddit figures are not based on the Irish forecast, they are taken from various other countries.
    The Reddit figures exclude J&J, Curevac and Novax.
    It's based on Pfizer, Moderna & AZ only.


  • Posts: 543 ✭✭✭ [Deleted User]


    Results are in for the AstraZeneca US trial. 79% efficacy overall with 100% efficacy against severe disease. Consistant across all ethnicities and age groups. No safety issues.

    https://www.astrazeneca.com/media-centre/press-releases/2021/astrazeneca-us-vaccine-trial-met-primary-endpoint.html


  • Registered Users, Registered Users 2 Posts: 4,241 ✭✭✭Sanjuro


    Hardyn wrote: »
    Results are in for the AstraZeneca US trial. 79% efficacy overall with 100% efficacy against severe disease. Consistant across all ethnicities and age groups. No safety issues.

    https://www.astrazeneca.com/media-centre/press-releases/2021/astrazeneca-us-vaccine-trial-met-primary-endpoint.html

    I presume they'll start using the millions of doses they've stockpiled now?


  • Registered Users, Registered Users 2 Posts: 32,132 ✭✭✭✭is_that_so


    Sanjuro wrote: »
    I presume they'll start using the millions of doses they've stockpiled now?
    AZ need to apply for approval first, so more likely up to a month away.


  • Registered Users, Registered Users 2 Posts: 883 ✭✭✭eoinbn


    Wolf359f wrote: »
    Reddit figures are not based on the Irish forecast, they are taken from various other countries.
    The Reddit figures exclude J&J, Curevac and Novax.
    It's based on Pfizer, Moderna & AZ only.

    I stand corrected - partly! They come up with a figure of 5.25m 2 dose vaccines by the end of June. I don't see how they get there without Curevac and more.
    Q1 1.1M
    Q2: Pfizer 2.2m, AZ .77m and Moderna .4m gives a total of 4.47m for the first two quarters. Add in J&J and it looks pretty decent - however that is best case scenario. There are still question marks over the supply of all 4 suppliers as all 4 require a huge ramp up and AZ has failed to meet any and all deadlines.


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  • Moderators, Entertainment Moderators Posts: 18,045 Mod ✭✭✭✭ixoy


    My Mum got her first dose on Saturday - delighted!


This discussion has been closed.
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