COVID-19: Vaccine and testing procedures Megathread Part 3 - Read OP

robinph · 20-03-2021 10:31PM

Stark wrote: »

It seems to be linked to under-50s and healthcare workers are pretty much the only under-50s receiving it at the moment.

7 million people aged 16-64 with underlying conditions, or just a carer for someone with underlying conditions, have received the vaccine in the UK. Plenty of younger people vaccinated with Astra Zeneca, and health care workers were jabbed earlier on, but possibly more Pfizer jabs.

noplacehere · 20-03-2021 11:20PM

thecretinhop wrote: »

got a text at 2pm to get first vaccine text yes or no. i have a few ailmemts puts me in cat 4. i whould have thought moderate enough high bp etc. anyway is it legit? its for monday:eek:

Take it. I’m cat 4 and would take it in a heart beat!!

Icantthinkof1 · 20-03-2021 11:56PM

thecretinhop wrote: »

got a text at 2pm to get first vaccine text yes or no. i have a few ailmemts puts me in cat 4. i whould have thought moderate enough high bp etc. anyway is it legit? its for monday:eek:

Delighted for you
I just looked back over the text I received when offered mine it read as follows;
Action required (my name) your 1st vaccine dose is (date, time and location)
Reply yes to confirm or no to cancel
(They also send a text the day before to remind you)

Goldengirl · 21-03-2021 12:33AM

Tippbhoy1 wrote: »

Countries in the main so far are only vaccinating older people and health care workers, and as AZ isn’t being given to the older cohort then the recipients are only hcw’s. Re female, at a guess the industry is dominated by females but that is a very simplistic reason, maybe contraceptive pill could be a factor too. Both guesses on my part

You are right there, re hcws and mostly female.
Not about the ocp or hrt though despite both being known to be a risk factor for thrombus formation.
They were out ruled as causes when it first broke, as the type of thrombus formation ( in the brain) and with the platelet irregularities found are not the same as those found due to hormonal treatment.

Micky 32 · 21-03-2021 12:50AM

Are NEPHET trying to put people off vaccines with their “ NEPHET warn vaccines will offer limited protection”

stephenjmcd · 21-03-2021 12:53AM

Micky 32 wrote: »

Are NEPHET trying to put people off vaccines with their “ NEPHET warn vaccines offer limited protection”

As I posted in the main thread

"I mean the letter is over a month old when the impact of vaccination still wasn't as clear as it is now.

As the saying goes a paper never refuses ink"

The letters over a month old, the impact of vaccination wasn't as clear then as it is now. The letter is a snapshot of time then, doesn't mean its a snapshot of time now as more evidence has built since then regarding vaccination. Something to keep in mind.

Would question why the Independent felt the need to throw that month old letter onto the front page in what's a dynamic situation in terms of vaccination

IRISHSPORTSGUY · 21-03-2021 01:28AM

How can the EU export ban to the UK work if Lipids (a key component of the Pfizer vaccine), are made in the UK? Can they be sourced elsewhere or is Ursula VDL being inept again?

User142 · 21-03-2021 01:55AM

IRISHSPORTSGUY wrote: »

How can the EU export ban to the UK work if Lipids (a key component of the Pfizer vaccine), are made in the UK? Can they be sourced elsewhere or is Ursula VDL being inept again?

Completely open to correction here but as Pfizer are meeting their contractual requirements their exports wouldn't be restricted. I think AZ are the only producer within the scope of these measures.

Wolf359f · 21-03-2021 02:35AM

IRISHSPORTSGUY wrote: »

How can the EU export ban to the UK work if Lipids (a key component of the Pfizer vaccine), are made in the UK? Can they be sourced elsewhere or is Ursula VDL being inept again?

I'm not 100% sure but I think the new Pfizer factory financed by Germany is self sufficient.
Also lipids are also produced in Switzerland, but they maybe for moderna.
EU could block exports of Pfizer just to the UK, if the UK in turn block lipids exports to the EU, then all countries apart from the USA suffer.
I think the EU are trying to make people realise the vaccine nationalism is having knock on effects.
AZ has proven to be a bust in the western world, not the vaccine, the production. The other key vaccine is Pfizer and having the worldwide production (apart from the US) in a few factories in the EU is a near impossible task.
Pfizer was never meant to be the backbone of vaccination, but it's looking to be.

thecretinhop · 21-03-2021 09:29AM

Icantthinkof1 wrote: »

Delighted for you
I just looked back over the text I received when offered mine it read as follows;
Action required (my name) your 1st vaccine dose is (date, time and location)
Reply yes to confirm or no to cancel
(They also send a text the day before to remind you)

yep 100pc same epic. thsnks so much

Van.Bosch · 21-03-2021 09:46AM

I wonder how the vaccine reporting will change when J&J starts being rolled out. Will need a way to see that those people are fully vaccinated and a second dose isn’t required.

irishgeo · 21-03-2021 09:52AM

Van.Bosch wrote: »

I wonder how the vaccine reporting will change when J&J starts being rolled out. Will need a way to see that those people are fully vaccinated and a second dose isn’t required.

Just include them in the 2nd category as fully vaccinated.

NeuralNetwork · 21-03-2021 10:04AM

Interesting, the U.K. articles on that lipid production could be getting the wrong end of the stick.

The Pfizer lipid delivery system is made by a US company called Avanti Polar Lipids which was acquired by Croda International Plc in July 2020.

It’s not clear that the products are made in the U.K. at all. They seem to be essentially American tech.

https://avantilipids.com/

https://cen.acs.org/business/outsourcing/Pfizer-signs-Croda-vaccine-excipients/98/i44

The distribution seems to be by Merck (German) in Germany and also Evonik is involved with the production of these liposome delivery systems in a big way both in Germany & the USA

https://corporate.evonik.com/en/media/press-releases/corporate/fight-against-covid-19-evonik-supplies-key-technology-for-gene-based-drugs-149707.html

None of the countries involved are self sufficient entirely. There’s supply chain and technology codependencies between the US and EU for example on a lot of this stuff.

Some of the key lipid tech involved in this also originated in Canada.

A lot of the very specialised machines that produce the lipids are also European.

If you start going into nationalism on this stuff it just does not work. Global supply chains are global and that’s why Trump & Brexiteers are lost in the 1950s (or 1850s...)

These companies aren’t multinationals for nothing.

is_that_so · 21-03-2021 10:25AM

astrofool wrote: »

They're generally the ones getting vaccines at this stage of the rollout, also a high proportion are relatively young and female.

Important thing to note is that these 2 cases were of people who had the vaccine in the 14 days prior, there is no evidence of a causal link between the two, and from data received so far, they probably would have had thrombotic events if they hadn't been vaccinated.

The WSJ article linked to some pages back suggested there is a causal link but there is also a proposed solution and instructions for AZ have been updated as a result of the pause.

JTMan · 21-03-2021 12:03PM

https://twitter.com/BBCPolitics/status/1373570946787852288

St.Spodo · 21-03-2021 12:06PM

"Vaccines will only offer limited protection between now and summer unless case numbers fall significantly".

That is a responsible statement, is it not? We'll only have perhaps one third of the population vaccinated by late May, early June. In that context, if the virus were to spread quickly among the rest of the population, it could still do a lot of damage.

is_that_so · 21-03-2021 12:10PM

St.Spodo wrote: »

"Vaccines will only offer limited protection between now and summer unless case numbers fall significantly".

That is a responsible statement, is it not? We'll only have perhaps one third of the population vaccinated by late May, early June. In that context, if the virus were to spread quickly among the rest of the population, it could still do a lot of damage.

Like a lot of what has happened in this pandemic, snapshots and soundbytes cannot do justice to the complexity of the explanation. It has to be outlined in detail.

irishlad. · 21-03-2021 12:25PM

Just over 14k doses given on the 18th, the majority to cohort 3.

https://docs.google.com/spreadsheets/d/1cUZy6AMCwuA2zhtRuKK7cqMVgmhdDsGsZrFWJTkw9DY/edit?usp=sharing

Bubbaclaus · 21-03-2021 01:12PM

irishlad. wrote: »

Just over 14k doses given on the 18th, the majority to cohort 3.

https://docs.google.com/spreadsheets/d/1cUZy6AMCwuA2zhtRuKK7cqMVgmhdDsGsZrFWJTkw9DY/edit?usp=sharing

Looks like it was the best day yet for doses given to Cohort 3. This week not looking as bad now as it could have been, particularly with AZ going to be back in the weekend numbers somewhat.

rm212 · 21-03-2021 01:17PM

Just got my first dose of AZ this morning (cohort 4). Very busy up in Beaumont Hospital but I have to say they’ve got a very efficient, professional system going on up there. You have to wait 15 mins after the vaccine in a waiting room and they’ve got bottles of water and packs of biscuits out for people, nice little touch from them.

Nice to see many young people up there with me getting it and not being skeptical or hesitant about AZ. Feeling quite ill now unfortunately but more than happy to put up with the headache, tiredness, upset stomach etc for a few days to get my vaccine. Absolutely over the moon about it, it was like Christmas morning going up there.

Sweet.Science · 21-03-2021 01:32PM

rm212 wrote: »

Just got my first dose of AZ this morning (cohort 4). Very busy up in Beaumont Hospital but I have to say they’ve got a very efficient, professional system going on up there. You have to wait 15 mins after the vaccine in a waiting room and they’ve got bottles of water and packs of biscuits out for people, nice little touch from them.

Nice to see many young people up there with me getting it and not being skeptical or hesitant about AZ. Feeling quite ill now unfortunately but more than happy to put up with the headache, tiredness, upset stomach etc for a few days to get my vaccine. Absolutely over the moon about it, it was like Christmas morning going up there.

Heard similar from friends this week . Always good to hear

Jim_Hodge · 21-03-2021 02:18PM

From the BBC this morning.

Chile's vaccination rate is the third highest in the world, according to some experts, but that hasn't stopped another resurgence in Covid-19. Infection rates are currently higher there than at any point in the pandemic.

Almost all hospital beds in the country are full and a new lockdown is being imposed in the capital Santiago.

More than 8.5 million vaccine doses have been administered in the country of 19 million people, according to Oxford University's Covid tracker. But officials say new variants and a relaxation of restrictions has led to the resurgence in cases.

I find this all very disconcerting.

hmmm · 21-03-2021 02:21PM

Jim_Hodge wrote: »

From the BBC this morning.

I find this all very disconcerting.

We've seen something similar in Israel, but there was an interesting graph posted earlier in the thread showing how it was the unvaccinated group making up the vast majority of hospitalisations and deaths.

Unless we're seeing mass hospitalisations of vaccinated groups, I'm not going to worry. But it does show I think that it is not sufficient simply to vaccinate the so-called "vulnerable" and then allow the disease to run rampant - it can overwhelm hospitals if enough of the non-vulnerable become sick.

Sweet.Science · 21-03-2021 02:24PM

hmmm wrote: »

We've seen something similar in Israel, but there was an interesting graph posted earlier in the thread showing how it was the unvaccinated group making up the vast majority of hospitalisations and deaths.

Unless we're seeing mass hospitalisations of vaccinated groups, I'm not going to worry. But it does show I think that it is not sufficient simply to vaccinate the so-called "vulnerable" and then allow the disease to run rampant - it can overwhelm hospitals if enough of the non-vulnerable become sick.

It's so rampant in Chile and Brazil that's it's hard to go 3 weeks after being vaccinated without getting Covid

charlie14 · 21-03-2021 02:36PM

Sweet.Science wrote: »

It's so rampant in Chile and Brazil that's it's hard to go 3 weeks after being vaccinated without getting Covid

Have you any data showing the numbers for either country that have been infected 3 weeks after being vaccinated ?

trellheim · 21-03-2021 02:47PM

Just a look back on deliveries

Debate here between myself and a few people on deliveries was in the main around whether it would be

850,000, 930,000, 1.1 million, 1.4 millon, or 1.7 million deliveries in Q1.

Latest published information ( and should be out again on Wednesday )

https://www.gov.ie/en/press-release/4f48c-update-on-covid-19-vaccine-deliveries-17-march-2021/

As of 17th March 758,490

Deliveries in the previous two weeks have been 93330 and 144,840

If that continues at that pace then averaging the two above approx 120,000 per week in 14 days to end of Q1 then we should make the million, with the extra promised Pfizer 45000 doses that should make 1.05 million. ( and I will have been wrong in underestimating it farther back in the thread )

Wolf359f · 21-03-2021 02:55PM

trellheim wrote: »

Just a look back on deliveries

Debate here between myself and a few people on deliveries was in the main around whether it would be

850,000, 930,000, 1.1 million, 1.4 millon, or 1.7 million deliveries in Q1.

Latest published information ( and should be out again on Wednesday )

https://www.gov.ie/en/press-release/4f48c-update-on-covid-19-vaccine-deliveries-17-march-2021/

As of 17th March 758,490

Deliveries in the previous two weeks have been 93330 and 144,840

If that continues at that pace then averaging the two above approx 120,000 per week in 14 days to end of Q1 then we should make the million, with the extra promised Pfizer 45000 doses that should make 1.05 million. ( and I will have been wrong in underestimating it farther back in the thread )

Unfortunately the last delivery of AZ was only 10k, so that will have an impact. Let's see if they can make up the shortfall by the end of Q1. One would hope AZ will try repair some of their reputation by trying to get a big delivery in before the end of Q1.

is_that_so · 21-03-2021 03:06PM

Vaccine diplomacy is generating tensions in Asia.

While western Europe’s “vaccine war” has been a struggle to prevent doses from being exported, in another part of the world, the battle is to give vaccines away.

https://www.theguardian.com/society/2021/mar/21/china-india-coronavirus-covid-vaccine-diplomacy-is-reaching-its-limit

Also the Serum Institute of India (SII) has told Brazil, Saudi Arabia and Morocco that further supplies of the AstraZeneca vaccine will be delayed due to surging demand at home.

We can probably expect to hear more of both stories.

PMBC · 21-03-2021 03:30PM

St.Spodo wrote: »

"Vaccines will only offer limited protection between now and summer unless case numbers fall significantly".

That is a responsible statement, is it not? We'll only have perhaps one third of the population vaccinated by late May, early June. In that context, if the virus were to spread quickly among the rest of the population, it could still do a lot of damage.

Id be interested to know where you got the 1/3 figure.
Based on current numbers of 450,000 one shot of two and 150,000 fully vaccinated (hope I got these figures correct) and the promised deliveries of 600,000 single shot/J&J and 3m of the double dose to end June - and I know that these may not come through - its possible that there could be 3.1 million people 'protected' by end June/first week July.
My 3.1 m calculation is made up of 2.5 m fully vaccinated and 0.6m single shot of two. It would represent >80% of the population over 18m. (CSO 2015 figures).
Agree or disagree?

ddarcy · 21-03-2021 03:40PM

Yevon wrote: »

My mother, Cohort 4, was due to be vaccinated last Monday before the pause on AZ. Just got a text to reschedule to tomorrow. So a week's delay.
Not bad at all given the circumstances.

Hoping we see big numbers vaccinated this week and reports of big deliveries on route by this time next week. People could do with some positive news.

Got to love the contacts to get the vaccine. Just got a text for one tomorrow, the AZ one. I thought I would be waiting until June to get it. I’m guessing they didn’t have enough in the current groups and moved me up. Now I need to rearrange my whole day tomorrow morning to get it. Should be fun I guess.

COVID-19: Vaccine and testing procedures Megathread Part 3 - Read OP

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