What exactly is happening with AstraZeneca?

Sam Russell · 02-02-2021 01:00PM

Tyrone212 wrote: »

Russian vaccine 92% efficiency
Zero hospitalisations/deaths
Zero severe reactions
Trial of 20k people
Published in lancet today

Better Efficiency than Oxford. We should order it.

It would be too Rusky.

Tyrone212 · 02-02-2021 01:03PM

Sam Russell wrote: »

It would be too Rusky.

I don't think some people will be Putin it in them.

robinph · 02-02-2021 01:06PM

Pete_Cavan wrote: »

That is complete and utter bull. There should be bans for still repeating it.

Merely working from recent quotes attributed to AZ bosses in articles in the Italian press and re quoted by the BBC in January where they stated that the production in the EU was 2 months behind that in the UK currently.

Maybe they knew more about what was going to occur in January 2021 back in July 2020 though?

niallo27 · 02-02-2021 01:06PM

Tyrone212 wrote: »

I don't think some people will be Putin it in them.

I wouldn't be russian to get it anyway, I'll get my coat.

02-02-2021 01:25PM

Tyrone212 wrote: »

Russian vaccine 92% efficiency
Zero hospitalisations/deaths
Zero severe reactions
Trial of 20k people
Published in lancet today

Better Efficiency than Oxford. We should order it.

Well they only applied for approval a week ago

mick987 · 02-02-2021 01:29PM

Deleted User wrote: »

Well they only applied for approval a week ago

Going by the EU past performance on vaccines we will get it in 2024 if we are lucky.

SteM · 02-02-2021 01:41PM

mick987 wrote: »

Going by the EU past performance on vaccines we will get it in 2024 if we are lucky.

They should just click their fingers and it will magically appear I suppose?

astrofool · 02-02-2021 01:47PM

mick987 wrote: »

Going by the EU past performance on vaccines we will get it in 2024 if we are lucky.

3 weeks from application to approval for AstraZeneca wasn't it? Now, I know we're living in a 24/7 COVID news bubble, but that's quick for a medicine isn't it? Sputnik also seems to have all the data and dosage regimen in order, which should help.

Mr. Karate · 02-02-2021 01:48PM

Waterford Regional Hospital/University Hospital Waterford are supposed to receive 35,000 AstraZeneca vaccines next week.

So deadly they can afford to drag their feet. :rolleyes:

02-02-2021 01:58PM

mick987 wrote: »

Going by the EU past performance on vaccines we will get it in 2024 if we are lucky.

Why do you think that?
The Pfizer one was applied for on 1st December and granted on the 21st
The Moderna was applied for on 1st December and granted on the 6th January
The AZ one was applied for on 12th January and approved 30th January

So, an average of 25 days for the three processes. Why do you think it will take 3+ years instead of 3+ weeks?

micosoft · 02-02-2021 02:13PM

robinph wrote: »

Just t0 put your mind at ease on this point, you do know that the internet is global right?

Sigh. Except most folk that think for a minute recognise that it's turned into a bunch of echo chambers and it's accurate to say there is far more bleed of UK based media to Ireland than vice versa and certainly vs French, German media to Ireland? Or are you seriously suggesting that you are as up to date with Kronen Zeitung as you are with the BBC? Just play that back in your mind for a minute...

micosoft · 02-02-2021 02:22PM

robinph wrote: »

Do we know when these production issues were identified by AZ?
When were the EU made aware of them?

https://www.bbc.co.uk/news/world-europe-55817633

Same problems with the EU based plants as were happening in the UK ones, but the UK ones had a 3 month headstart over the EU ones.

The article also mentions that Pfizer have slowed production to the EU as well. Should they have checked with the EU before doing that so that the EU could have said to wait a bit on their upgrade because AZ have some other problems at the moment and they need something from somewhere? It's a few unfortunate things all seem to have happened at the same time and hit the EU vaccine program. Its a bit of bad luck, but kicking off a fight about it is probably not the best resolution.

Demanding things like your full quota of vaccine when it's not currently possible to provide it is all a bit futile and just makes the EU out to be the toddler screaming about their ice cream mentioned previously.

Except replace ice cream with dead bodies and toddler with 27 Governments who are facing riots. I find it fascinating that the Tory party line that this is a contract dispute has embedded itself in the Irish narrative worrying.

Not a single person is claiming that AZ should have magicked vaccines out of thin air. Clearly the issue being brought to the forefront here is:

1. The lack of notice from AZ. For something this important there is a team in AZ whose only role should be communicating to the EU. You don't drop to 30% overnight. The unusual rage of the EU, known for being calm during the entire Brexit process would suggest this was an unprecedented surprise.
2. The lack of equity where another customer is getting 100% while you are getting 30%. Again, the suggestion that the EU having the best legal and trading skills in the world (according to most Trumps own trade commissioner) would accidently sign a contract late that was just "best effort" is implausible.

That's what this boils down to.

mick987 · 02-02-2021 03:12PM

Deleted User wrote: »

Why do you think that?
The Pfizer one was applied for on 1st December and granted on the 21st
The Moderna was applied for on 1st December and granted on the 6th January
The AZ one was applied for on 12th January and approved 30th January

So, an average of 25 days for the three processes. Why do you think it will take 3+ years instead of 3+ weeks?

Approved but not received.

02-02-2021 03:25PM

mick987 wrote: »

Approved but not received.

Wtf are you talking about? I've no idea what point you're trying to make here but, rest assured, you're making a complete bollocks of it whatever it is.

You suggested it will take over three 3 years to approve a new vaccine, based on past performance. However that past performance has shown that it actually only takes a little over three weeks for approval, not three years.

Delivery of those vaccines is the remit of the supplier, not the contractor. The contractor (the EU) can do all of the necessary work in the background to mitigate against any unforeseen interruptions, but when everything goes wrong and they're unable to deliver as promised, then it is the supplier's fault, not the contractor.

You do realise this, yeah? If you order a pizza and the delivery driver drops it on the ground, that's his fault, not yours, yeah?

So, please, enlighten us as to why you think it will be 2024 before the Russian vaccine is delivered based on past performance.

brickster69 · 02-02-2021 05:51PM

micosoft wrote: »

Except replace ice cream with dead bodies and toddler with 27 Governments who are facing riots. I find it fascinating that the Tory party line that this is a contract dispute has embedded itself in the Irish narrative worrying.

Not a single person is claiming that AZ should have magicked vaccines out of thin air. Clearly the issue being brought to the forefront here is:

1. The lack of notice from AZ. For something this important there is a team in AZ whose only role should be communicating to the EU. You don't drop to 30% overnight. The unusual rage of the EU, known for being calm during the entire Brexit process would suggest this was an unprecedented surprise.

A UK minister made a statement on Sunday saying that British engineers were sent to the plant in question to fix capacity issues a month earlier. So you would imagine issues were known before then at least on one side.

No way to know if the Minister is telling the truth or no way to know if AZ or the sub contractors had informed the EU about production problems.

Bad form if neither of them did not though. Bad form also if they were informed of issues earlier and the EU did not report it.

brickster69 · 02-02-2021 07:02PM

Pfizer expecting $4 Billion profit from current $15 billion sales this year. With margins to increase as the pandemic goes on.

https://www.ft.com/content/0f1ab138-401d-40ff-824f-f6879704f10e?accessToken=zwAAAXf9ij4Wkc8PGrE4QB1A_9OCT_aHlwTxDgE.MEUCIFnYizS7k6SGN9RXpPRy3AQmqfrssdokxZTnbcgM4R0gAiEAoUv8XK0HQENbSgRoU8E1N_nXSmOCx8ZvF5awth1yF9Y&segmentId=0f1ab138-401d-40ff-824f-f6879704f10e

...Ghost... · 02-02-2021 11:00PM

The UK have now detected a variant with atleast some resistance to the vaccine.

ShineOn7 · 02-02-2021 11:55PM

...Ghost... wrote: »

The UK have now detected a variant with atleast some resistance to the vaccine.

Just AZ?

Or Pfizer too?

NeuralNetwork · 03-02-2021 12:12AM

ShineOn7 wrote: »

Just AZ?

Or Pfizer too?

Seems the tests were involving serum from patients who'd a single dose of the Pfizer/BioNTech vaccine : https://www.cidrap.umn.edu/news-perspective/2021/02/new-variant-covid-findings-fuel-more-worries-about-vaccine-resistance

dogbert27 · 03-02-2021 08:34AM

brickster69 wrote: »

A UK minister made a statement on Sunday saying that British engineers were sent to the plant in question to fix capacity issues a month earlier. So you would imagine issues were known before then at least on one side.

No way to know if the Minister is telling the truth or no way to know if AZ or the sub contractors had informed the EU about production problems.

Bad form if neither of them did not though. Bad form also if they were informed of issues earlier and the EU did not report it.

This is typical nationalism nonsense. Pharmaceutical companies have their own process engineers and maintenance teams who look after the production equipment.
"British engineers". Engineers in being British? :rolleyes:

Call me Al · 03-02-2021 08:53AM

brickster69 wrote: »

A UK minister made a statement on Sunday saying that British engineers were sent to the plant in question to fix capacity issues a month earlier........

What a bizarre and unhelpful thing for a government minister to say.
Did the UK government send in these engineers?
Did their need to present their passports to prove they were sufficiently British?
What if they were dual citizens?
Were they required to state an opinion on Brexit to get the job too?
I think the level of constant "them and us" epitomised by comments such as this is proving extremely unhelpful to everyone.
It's a long road without a turn, so there's no point in pissing off half your population and most of your neighbours with pointless words like this.

Bass Reeves · 03-02-2021 09:20AM

Call me Al wrote: »

What a bizarre and unhelpful thing for a government minister to say.
Did the UK government send in these engineers?
Did their need to present their passports to prove they were sufficiently British?
What if they were dual citizens?
Were they required to state an opinion on Brexit to get the job too?
I think the level of constant "them and us" epitomised by comments such as this is proving extremely unhelpful to everyone.
It's a long road without a turn, so there's no point in pissing off half your population and most of your neighbours with pointless words like this.

It was probably a Paddy, a Pakistani and two Indians.

Tyrone212 · 03-02-2021 09:27AM

Nauseating nationalism. Reminds me of their education secretary saying there were a better country than the French etc because the vaccine they used in December, even though it came from the EU.

03-02-2021 09:33AM

Positive news to be published in the Lancet after peer review

https://www.theguardian.com/society/2021/feb/02/single-dose-of-astrazeneca-vaccine-could-cut-transmission-by-67

mick087 · 03-02-2021 09:45AM

Deleted User wrote: »

Positive news to be published in the Lancet after peer review

https://www.theguardian.com/society/2021/feb/02/single-dose-of-astrazeneca-vaccine-could-cut-transmission-by-67

This is good news.
The vaccine seems our only way out this awful situation we are all in.

BoatMad · 03-02-2021 09:55AM

mick087 wrote: »

This is good news.
The vaccine seems our only way out this awful situation we are all in.

Good news too studies showing AZ vaccine prevents transmissions

Now we need to get off our arses

mick087 · 03-02-2021 10:08AM

BoatMad wrote: »

Good news too studies showing AZ vaccine prevents transmissions

Now we need to get off our arses

Roll out of vaccines has started.
6 months time most if not all in Ireland and many other countries will be done.

Hopefully the poorer countries will not have to wait to long.

IRISHSPORTSGUY · 03-02-2021 12:03PM

Do we know if it'll take days to get into the country and set up or do vaccinations start on the 8th?

CIARAN_BOYLE · 03-02-2021 12:08PM

IRISHSPORTSGUY wrote: »

Do we know if it'll take days to get into the country and set up or do vaccinations start on the 8th?

Its arriving sometime on the week of the 8th. We don't have a confirmed date of arrival.

drunkmonkey · 03-02-2021 12:20PM

BoatMad wrote: »

Good news too studies showing AZ vaccine prevents transmissions

Now we need to get off our arses

It is and it isn't they'll use that data to put off the second jab as recommend. I'd feel a lot happier it they stuck to the plan. Cutting the chance of transmitting it by only 60% aren't great odds, no restrictions can be lifted.

What exactly is happening with AstraZeneca?

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