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COVID-19: Vaccine/antidote and testing procedures Megathread [Mod Warning - Post #1]

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  • Registered Users, Registered Users 2 Posts: 2,308 ✭✭✭Irish Stones


    El Sueño wrote: »
    Any source? Link? Video? Anything?

    The TV channel's server hasn't the program available yet. I guess they upload the day programs only at the end of the day. The last Sunday's program is available, I will check it again tomorrow and let you know.
    At the end of the day if you post nonsense sensationalist claims (such as the above or your previous claim that there wouldn't be a vaccine until 2023) you'll get called out on it.

    Well, officially we haven't any vaccine yet.


  • Posts: 0 [Deleted User]


    The interview should be available on the server of the broadcaster tomorrow, I guess, because right now only last Sunday's program is available.
    It's an hour long program, with a few interviews, and one of this was telling what I wrote above.
    I'll check it again tomorrow and if I find the link to the program I will provide it. It'll be in Italian, I think you're good with the language enough to understand it.

    Anytime I was in Italy I always thought the news programmes looked quite melodramatic when discussing the most mundane topics, so can only imagine what they are like when discussing Covid. There are no manufacturing issues which will delay either of the vaccines mentioned until 2022


  • Registered Users, Registered Users 2 Posts: 2,419 ✭✭✭Cork2021


    Uk will have at least another 4million doses of vaccine before year end if this happens. EMA need to pull the finger out!!

    https://www.dailymail.co.uk/news/article-9048539/amp/Pretty-high-chance-Oxford-vaccine-rolled-end-year.html


  • Registered Users, Registered Users 2 Posts: 215 ✭✭Ce he sin


    El Sueño wrote: »
    Any source? Link? Video? Anything?

    At the end of the day if you post nonsense sensationalist claims (such as the above or your previous claim that there wouldn't be a vaccine until 2023) you'll get called out on it.
    I think the poster is referring to the Sanofi/GSK vaccine which has been found in trials to be less effective than hoped for older people and whose rollout will therefore be delayed until it can be reformulated and retested.


  • Posts: 0 [Deleted User]


    Ce he sin wrote: »
    I think the poster is referring to the Sanofi/GSK vaccine which has been found in trials to be less effective than hoped for older people and whose rollout will therefore be delayed until it can be reformulated and retested.

    And it is now expected in the second half of 21. I.e not 2022. Astrazeneca will be shipping as soon as approved


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  • Moderators, Science, Health & Environment Moderators Posts: 14,648 Mod ✭✭✭✭marno21


    Ce he sin wrote: »
    I think the poster is referring to the Sanofi/GSK vaccine which has been found in trials to be less effective than hoped for older people and whose rollout will therefore be delayed until it can be reformulated and retested.
    And indeed would be cause for concern if only there wasn't 5 other vaccines expected to be approved and deployed before this one.


  • Registered Users, Registered Users 2 Posts: 2,065 ✭✭✭funnydoggy




    Well, officially we haven't any vaccine yet.


    Who's we? 'cos the US and the UK have one now. On the island of Ireland, people are being vaccinated.

    The antagonism is getting boring.


  • Registered Users, Registered Users 2 Posts: 15,643 ✭✭✭✭Supercell


    Morocco is planning on having 80% of its adult population vaccinated this month whilst the EMA dawdles along.
    Reading on rte.ie that Martin is saying that the vaccine wont be available to most of the population here until May or June, so we are six months behind other countries already..lets hope the same people that are involved in the National Children's hospital debacle are not making important decisions here or it will be May/June 2022.

    Have a weather station?, why not join the Ireland Weather Network - http://irelandweather.eu/



  • Registered Users, Registered Users 2 Posts: 2,308 ✭✭✭Irish Stones


    I'll check it again tomorrow and if I find the link to the program I will provide it. It'll be in Italian, I think you're good with the language enough to understand it.

    I found what I was talking about.
    This link takes you to a news article (2 minutes long) from a news program of yesterday at 1pm

    https://www.mediasetplay.mediaset.it/video/tg5/vaccini-lobiettivo-e-partire-il-15-gennaio_F310153701390D03

    The article begins with the description of the current situation in our country. We have the European record for deaths from Covid, at least we are first in something :D
    Then it says about our vaccination campaign, with the aim (impossible, in my opinion) to give the vaccine to the whole Italian population within September, through 1,500 distribution centres and over 20,000 doctors and nurses involved.
    It ends with the words (timecode 1:45) that Sanofi will give us their doses only in 2022 due to a technical issue, accounting for about 20% of the total doses we were waiting for.

    The second link is from the program I told you about

    https://www.raiplay.it/video/2020/12/Mezzora-in-piu-90745759-d71c-47c0-8fa9-7a65d31f5559.html

    It begins with the interview to one our more famous senior doctors, founder of an NGO called Emergency. I am sure you have never heard of it, but over here it's very well known for their commitment to health care to civilians in war-torn countries. He says that he fears that the distribution in poorer countries might be slower and this might affect the success of a world vaccination. He also says that the vaccines will reduce the deaths, but won't stop the virus spreading, so unless the herd immunity is reached, the pandemic won't be stopped. He adds that the AZ vaccine has an efficacy of 62-90% which is too wide a range to be reliable and also has problem at supplying the 40 millions doses we are waiting for.
    Further into the program (timecode 10:45), it says about the problems AZ had with the continuity of production, leading to a raise in the shares value when they announced the vaccine, followed by a collapse of the same shares three days later, along with the confusing data on the trials and (timecode 11:16 - 11:48) the not too representative panel of volunteers.
    At timecode 13:02 - 13:40 they talk about the problems that AZ and Sanofi had in the production, and how Sanofi has to work again on the vaccine because they're using a protein from the HIV virus which might lead to a positive test for HIV when a person receives this vaccine.

    A word of notice, the TV presenter in this program has a strong southern accent, that might sound unintellegible to a non-Italian speaker. The raspy voice of the senior doctor might also be a barrier to the comprehension of what he's saying.

    I'm available to further translations, if you're interested.

    Hopefully you Irish have the rights to access the links due to geographic and regional copyrights.


  • Registered Users, Registered Users 2 Posts: 2,308 ✭✭✭Irish Stones


    funnydoggy wrote: »
    Who's we? 'cos the US and the UK have one now. On the island of Ireland, people are being vaccinated.

    The antagonism is getting boring.


    We European who are waiting for the EMA approval. Technically, until a vaccine is approved, there's no vaccine.


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  • Registered Users, Registered Users 2 Posts: 15,443 ✭✭✭✭stephenjmcd


    Ce he sin wrote: »
    I think the poster is referring to the Sanofi/GSK vaccine which has been found in trials to be less effective than hoped for older people and whose rollout will therefore be delayed until it can be reformulated and retested.

    Sanofi/ GSK is indeed put back a few months.

    AstraZeneca on the other hand is not so posting that both are delayed until 2022 is rubbish as others have pointed out.

    AstraZeneca & Oxford will be delayed in the USA but in Europe it looks fine to submit for approval once full phase 3 readouts are completed


  • Registered Users, Registered Users 2 Posts: 5,977 ✭✭✭Russman


    Sanofi/ GSK is indeed put back a few months.

    AstraZeneca on the other hand is not so posting that both are delayed until 2022 is rubbish as others have pointed out.

    AstraZeneca & Oxford will be delayed in the USA but in Europe it looks fine to submit for approval once full phase 3 readouts are completed

    Wonder is it fair to assume a similar time gap between interim results and full phase 3 results as Pfizer & Moderna had ? What was it, 2/3 weeks between interim & final for each ?


  • Registered Users, Registered Users 2 Posts: 2,004 ✭✭✭Hmmzis


    Bahrain has also approved the Sinopharm vaccine for general distribution.

    Official statement here


  • Closed Accounts Posts: 134 ✭✭Henryq.


    Surely the countries approving quickly are getting a double boost

    They're vaccinating right now and getting ahead of the inevitable shortfalls in production


  • Registered Users, Registered Users 2 Posts: 15,443 ✭✭✭✭stephenjmcd


    Russman wrote: »
    Wonder is it fair to assume a similar time gap between interim results and full phase 3 results as Pfizer & Moderna had ? What was it, 2/3 weeks between interim & final for each ?

    Yeah about that, all depends on infection levels in the areas where they're testing really.

    Hopefully hear something this side of Christmas and then it slots in a few weeks behind Moderna in the EMA timeline fingers crossed


  • Registered Users, Registered Users 2 Posts: 1,580 ✭✭✭JDD


    Does anyone know when the Astra Zeneca crowd will be submitting to the EMA for approval? I know they decided to go back and do more testing on the 1 dose + half a dose regime, but any idea when that second round of Phase 3 testing will be complete?

    I don't think we're far off EMA approval for Pfizer. Days away really. It's obviously going to take a little longer to approve a vaccine for 26 countries than it is for one, and we all decided that we'd go down the group approval route. I have no particular issue with whatever our regulator is here, but in general I have a higher trust in a Europe-wide approval than I would with an Irish only approval. That may be because the Irish have a lower level of trust in their government institutions then the Brits do, but that's the way I feel.


  • Registered Users, Registered Users 2 Posts: 15,443 ✭✭✭✭stephenjmcd


    JDD wrote: »
    Does anyone know when the Astra Zeneca crowd will be submitting to the EMA for approval? I know they decided to go back and do more testing on the 1 dose + half a dose regime, but any idea when that second round of Phase 3 testing will be complete?

    I don't think we're far off EMA approval for Pfizer. Days away really. It's obviously going to take a little longer to approve a vaccine for 26 countries than it is for one, and we all decided that we'd go down the group approval route. I have no particular issue with whatever our regulator is here, but in general I have a higher trust in a Europe-wide approval than I would with an Irish only approval. That may be because the Irish have a lower level of trust in their government institutions then the Brits do, but that's the way I feel.

    On AstraZeneca what they published was interim results. They still require phase 3 to complete, that all depends on infections in the test group really.

    The second round of phase 3 is really only to benefit the FDA, they won't accept the half dose full dose in its current state and it wasn't a trial ran in the USA.


  • Registered Users, Registered Users 2 Posts: 8,731 ✭✭✭BrianD3


    Supercell wrote: »
    Morocco is planning on having 80% of its adult population vaccinated this month whilst the EMA dawdles along.
    Reading on rte.ie that Martin is saying that the vaccine wont be available to most of the population here until May or June, so we are six months behind other countries already..lets hope the same people that are involved in the National Children's hospital debacle are not making important decisions here or it will be May/June 2022.
    Yes, Martin was saying on RTE radio that he "wants" and "hopes to be in a position to" start vaccinating within a week of EMA approval. A lot of other non committal language also.
    https://www.rte.ie/news/2020/1213/1184225-ronan-glynn-vaccines/

    Given the HSE's track record, hoping for and wanting a particular outcome are likely to result in not achieving that outcome.

    I'd say there' s a good chance now that we will f*ck up the logistics, hopefully I'm wrong. Getting close to Christmas now too, at this time of the year there's a culture in the public service of winding down and putting things off until the New Year, maybe things will be different this time.

    As for the EMA, good to see they are getting some flak. The British will be giving their vulnerable and healthcare workers booster shots while the EMA is having a meeting. Lots of anti British sentiment out there including some on this forum. This is clearly an emergency situation and while the EMA will do a very thorough appraisal of the vaccine, there would seem to be a danger of allowing the "near perfect to become the enemy of the excellent".

    The faster the vaccine gets approved, the higher the chances of the HSE/Ireland and other countries getting caught with their pants down re: logistics. We might be more exposed than most given that Ireland was one of only 2 countries of the EU 27 that didn't respond to the EU HSC survey on vaccine rollout preparations.


  • Closed Accounts Posts: 134 ✭✭Henryq.


    BrianD3 wrote: »
    Yes, Martin was saying on RTE radio that he "wants" and "hopes to be in a position to" start vaccinating within a week of EMA approval. A lot of other non committal language also.
    https://www.rte.ie/news/2020/1213/1184225-ronan-glynn-vaccines/

    Given the HSE's track record, hoping for and wanting a particular outcome are likely to result in not achieving that outcome.

    I'd say there' s a good chance now that we will f*ck up the logistics, hopefully I'm wrong. Getting close to Christmas now too, at this time of the year there's a culture in the public service of winding down and putting things off until the New Year, maybe things will be different this time.

    As for the EMA, good to see they are getting some flack. The British will be giving their vulnerable and healthcare workers booster shots while the EMA is having a meeting. Lots of anti British sentiment out there including some on this forum. This is clearly an emergency situation and while the EMA will do a very thorough appraisal of the vaccine there would seem to be a danger of allowing the "near perfect to become the enemy of the excellent".

    The faster the vaccine gets approved the higher the chances of the HSE/Ireland and other countries getting caught with their pants down re: logistics. We might be more exposed that most given that Ireland was one of only 2 countries of the EU 27 that didn't respond to the EU HSC survey on vaccine rollout preparations.

    At this stage we'd be better off with press conferences on vaccine rollout and not covid numbers


  • Banned (with Prison Access) Posts: 547 ✭✭✭BeefeaterHat


    https://www.rte.ie/news/2020/1213/1184225-ronan-glynn-vaccines/

    Micheal with the excuses a the ready. By comparison, Japan hope to have 120 million people vaccinated by the summer time and the UK are already getting people vaccinated. Watch now and while the rest of Europe goes back to normal, the HSE and nphet and the government will be putting on a modern day carry on film while they shamble about.


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  • Registered Users, Registered Users 2 Posts: 10,008 ✭✭✭✭cgcsb


    The BBC seems to hint at April as a date for widespread uptake of the vaccine. I notice RTÉ mention June today. June just seems a really long way off considering the rolling lock downs. Also surely a country as sparsely populated as Ireland can roll it out faster than the UK and it's 70 million people??

    I'm assuming once the vulnerable are vaccinated then restrictions will go, what do people think?


  • Registered Users, Registered Users 2 Posts: 14,425 ✭✭✭✭leahyl


    Henryq. wrote: »
    At this stage we'd be better off with press conferences on vaccine rollout and not covid numbers

    Absolutely, there is no need for these press conferences anymore. We need to hear about vaccine rollout and what is planned and we need to know that they are ready to move as soon as EMA approve it.


  • Closed Accounts Posts: 134 ✭✭Henryq.


    cgcsb wrote: »
    The BBC seems to hint at April as a date for widespread uptake of the vaccine. I notice RTÉ mention June today. June just seems a really long way off considering the rolling lock downs. Also surely a country as sparsely populated as Ireland can roll it out faster than the UK and it's 70 million people??

    I'm assuming once the vulnerable are vaccinated then restrictions will go, what do people think?

    We seem to be very short on detail at this late stage

    We should have a national plan ready to go by now

    How many are trained and enlisted to administer the vaccine?


  • Registered Users, Registered Users 2 Posts: 784 ✭✭✭daydorunrun


    Quick question on testing-

    Is it possible to get a test anomalously? Or is it the case that all details of private testing are being recorded.

    Getting a pre Christmas test done but don't want any potential postive result effecting things like health and life insurance as I'm drawing down on a new mortgage in January and one of the questions on the life insurance is 'have you been diagnosed with Covid 19 in the last 6 months.

    “You tried your best and you failed miserably. The lesson is, never try.” Homer.



  • Banned (with Prison Access) Posts: 547 ✭✭✭BeefeaterHat


    cgcsb wrote: »
    The BBC seems to hint at April as a date for widespread uptake of the vaccine. I notice RTÉ mention June today. June just seems a really long way off considering the rolling lock downs. Also surely a country as sparsely populated as Ireland can roll it out faster than the UK and it's 70 million people??

    I'm assuming once the vulnerable are vaccinated then restrictions will go, what do people think?

    That's what should happen but unfortunately our health services are run by complete and utter morons who couldn't run a bath so we'll have to deal with this farce a little bit longer than other countries


  • Registered Users, Registered Users 2 Posts: 10,008 ✭✭✭✭cgcsb


    Henryq. wrote: »
    We seem to be very short on detail at this late stage

    We should have a national plan ready to go by now

    How many are trained and enlisted to administer the vaccine?

    The UK is currently relying on a large staff of volunteers, retired nurses, red cross etc. and converting sports stadiums to administer it in large numbers. Haven't heard of any such ramp up of capacity from the HSE. We're 2 weeks from approval apparently and not much info available. Places outside Europe are plowing ahead. Even the USA with notoriously difficult and expensive access to medication.


  • Registered Users, Registered Users 2 Posts: 15,443 ✭✭✭✭stephenjmcd


    cgcsb wrote: »
    The BBC seems to hint at April as a date for widespread uptake of the vaccine. I notice RTÉ mention June today. June just seems a really long way off considering the rolling lock downs. Also surely a country as sparsely populated as Ireland can roll it out faster than the UK and it's 70 million people??

    I'm assuming once the vulnerable are vaccinated then restrictions will go, what do people think?

    What was said was an interview with Martin this morning on rte.

    He said enough for priority groups in the early stages with larger volumes arriving March through April, May and June and what they expect is in the May / June period to be fully open.

    I don't often agree with what he says but he's probably right on that timeline I'd say.


  • Registered Users, Registered Users 2 Posts: 68,190 ✭✭✭✭seamus


    https://www.rte.ie/news/2020/1213/1184225-ronan-glynn-vaccines/

    Micheal with the excuses a the ready. By comparison, Japan hope to have 120 million people vaccinated by the summer time and the UK are already getting people vaccinated. Watch now and while the rest of Europe goes back to normal, the HSE and nphet and the government will be putting on a modern day carry on film while they shamble about.
    He's just setting realistic expectations. Some people will assume vaccine approval means game over, and restrictions can start being lifted.

    Every country will (does) have a severely limited supply until mid-Spring at the earliest. Japan will have half of their population vaccinated by the end of June (120 million doses). We're planning on 80% by September. Which is about the same, if not slightly ahead.

    It's incredible that before we even start anything, Irish people are so desperate to declare ourselves a failure.


  • Registered Users, Registered Users 2 Posts: 68,190 ✭✭✭✭seamus


    Quick question on testing-

    Is it possible to get a test anomalously? Or is it the case that all details of private testing are being recorded.

    Getting a pre Christmas test done but don't want any potential postive result effecting things like health and life insurance as I'm drawing down on a new mortgage in January and one of the questions on the life insurance is 'have you been diagnosed with Covid 19 in the last 6 months.
    All tests are anonymous. Neither the HSE nor your GP are entitled to reveal medical details to an insurer without your consent.

    Whether you tell the insurer about it, is between you and them. If you have already obtained an insurance policy and paid your first premium you don't have to tell them unless the policy document explicitly says you do.


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  • Posts: 0 [Deleted User]


    https://www.tagesschau.de/wirtschaft/unternehmen/curevac-corona-impfstoff-studie-phase3-101.html

    CureVac moving to Phase III. 35,000 participants across Europe and Latin America. Results expected by end of Q1 2021.


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