Advertisement
If you have a new account but are having problems posting or verifying your account, please email us on hello@boards.ie for help. Thanks :)
Hello all! Please ensure that you are posting a new thread or question in the appropriate forum. The Feedback forum is overwhelmed with questions that are having to be moved elsewhere. If you need help to verify your account contact hello@boards.ie

COVID-19: Vaccine/antidote and testing procedures Megathread [Mod Warning - Post #1]

1…171172174176177…325

Comments

  • #5192
    polesheep
    Closed Accounts Posts: 2,950 ✭✭✭polesheep


    landofthetree wrote: »
    They arent doing it for free.

    Do you think Ireland pre-EU membership could have negotiated the same number of vaccines as speedily?


  • #5193
    ShineOn7
    Closed Accounts Posts: 4,550 ✭✭✭ShineOn7


    Tears of joy as Pfizer staff told of vaccine breakthrough

    https://www.breakingnews.ie/world/tears-of-joy-as-pfizer-staff-told-of-vaccine-breakthrough-1031675.html


  • #5194
    ShineOn7
    Closed Accounts Posts: 4,550 ✭✭✭ShineOn7


    Tweeted 40 mins ago



    https://twitter.com/pfizer/status/1325848378564030464


  • #5195
    10000maniacs
    Registered Users, Registered Users 2 Posts: 5,589 ✭✭✭10000maniacs


    The scientific data produced by Pfizer will be most important on this new vaccine.
    90%+ on a sample of 43,000 people.
    What were the age ranges of these people? and how many people in that 43,000 had the virus to begin with?
    If nobody had the virus to begin with and the age range of the participants was 20-80, 90% is worse than the natural recovery rate for this sample in the real world.


  • #5196
    landofthetree
    Registered Users, Registered Users 2 Posts: 2,462 ✭✭✭landofthetree


    polesheep wrote: »
    Do you think Ireland pre-EU membership could have negotiated the same number of vaccines as speedily?

    Once you have the conkers you can buy it. Eg Switzerland have a deal.



    https://www.heidi.news/geneva-solutions/switzerland-has-assured-4-5-million-doses-of-future-covid-19-vaccine-through-moderna


  • Advertisement
  • #5197
    polesheep
    Closed Accounts Posts: 2,950 ✭✭✭polesheep


    landofthetree wrote: »
    Once you have the conkers you can buy it. Eg Switzerland have a deal.



    https://www.heidi.news/geneva-solutions/switzerland-has-assured-4-5-million-doses-of-future-covid-19-vaccine-through-moderna

    And if we hadn't got the conkers as EU members we would still get it.


  • #5198
    CIARAN_BOYLE
    Registered Users, Registered Users 2 Posts: 14,599 ✭✭✭✭CIARAN_BOYLE


    10000maniacs wrote: »
    The scientific data produced by Pfizer will be most important on this new vaccine.
    90%+ on a sample of 43,000 people.
    What were the age ranges of these people? and how many people in that 43,000 had the virus to begin with?
    If nobody had the virus to begin with and the age range of the participants was 20-80, 90% is worse than the natural recovery rate for this sample in the real world.

    It's 90% on a group of 94 (confirmed cases of covid) among the 43000.

    Also its not that 90% lived and 10% died.

    Rather than the people involved in a trial are divided into 2 randomly. Half given the vaccine and half given a placebo.

    Roughly 85 people in the placebo group have gotten covid compared to roughly 9 in the vaccinated group. They suggest this means that 90% of the people from the vaccinated group did not get covid because of the vaccine.


  • #5199
    timsey tiger
    Registered Users, Registered Users 2 Posts: 1,768 ✭✭✭timsey tiger


    10000maniacs wrote: »
    The scientific data produced by Pfizer will be most important on this new vaccine.
    90%+ on a sample of 43,000 people.
    What were the age ranges of these people? and how many people in that 43,000 had the virus to begin with?
    If nobody had the virus to begin with and the age range of the participants was 20-80, 90% is worse than the natural recovery rate for this sample in the real world.

    The number of positives was 94. None of the 43,000 had the virus before. The group is split in two those who got a placebo and those who got the vaccine.

    The 90% will refer to the proportion in each group who got the disease, with the proportion in the vaccinated group being less than 10% of the proportion in the placebo group.

    This is my understanding, I haven't given more than a passing look at it so I will have missed a lot of the subtleties.


  • #5200
    10000maniacs
    Registered Users, Registered Users 2 Posts: 5,589 ✭✭✭10000maniacs


    CIARAN_BOYLE wrote: »
    It's 90% on a group of 94 (confirmed cases of covid) among the 43000.

    Also its not that 90% lived and 10% died.

    Rather than the people involved in a trial are divided into 2 randomly. Half given the vaccine and half given a placebo.

    Roughly 85 people in the placebo group have gotten covid compared to roughly 9 in the vaccinated group. They suggest this means that 90% of the people from the vaccinated group did not get covid because of the vaccine.

    A better solution would be to 50/50 split the vaccine and placebo to people in vulnerable groups.
    And another 50/50 split to random people with the virus.


  • #5201
    big syke
    Registered Users, Registered Users 2 Posts: 903 ✭✭✭big syke


    10000maniacs wrote: »
    A better solution would be to 50/50 split the vaccine and placebo to people in vulnerable groups.
    And another 50/50 split to random people with the virus.


    Why give it to people with the virus???? It is not a treatment its a vaccine.

    You really arent grasping this well are you?


  • Advertisement
  • #5202
    Thierry12
    Closed Accounts Posts: 979 ✭✭✭Thierry12


    CIARAN_BOYLE wrote: »
    It's 90% on a group of 94 (confirmed cases of covid) among the 43000.

    Also its not that 90% lived and 10% died.

    Rather than the people involved in a trial are divided into 2 randomly. Half given the vaccine and half given a placebo.

    Roughly 85 people in the placebo group have gotten covid compared to roughly 9 in the vaccinated group. They suggest this means that 90% of the people from the vaccinated group did not get covid because of the vaccine.

    Were those 9 people sick?


  • #5203
    10000maniacs
    Registered Users, Registered Users 2 Posts: 5,589 ✭✭✭10000maniacs


    big syke wrote: »
    Why give it to people with the virus???? It is not a treatment its a vaccine.

    You really arent grasping this well are you?

    Aren't you the smug one?
    It's you that ain't grasping it. It all depends what type of vaccine it is. And what stage the virus is at in your system.
    And I meant giving the virus to the subject after the vaccine had been delivered.
    No need to be so arrogant in your replies.


  • #5204
    D.Q
    Registered Users, Registered Users 2 Posts: 6,054 ✭✭✭D.Q


    10000maniacs wrote: »
    A better solution would be to 50/50 split the vaccine and placebo to people in vulnerable groups.
    And another 50/50 split to random people with the virus.

    Mad they haven't hired you


  • #5205
    JacksonHeightsOwn
    Registered Users, Registered Users 2 Posts: 1,913 ✭✭✭JacksonHeightsOwn


    10000maniacs wrote: »
    A better solution would be to 50/50 split the vaccine and placebo to people in vulnerable groups.
    And another 50/50 split to random people with the virus.

    So you know more than these big pharma companies who, id imagine are experts in their field?


  • #5206
    10000maniacs
    Registered Users, Registered Users 2 Posts: 5,589 ✭✭✭10000maniacs


    chrisbonnie wrote: »
    So you know more than these big pharma companies who, id imagine are experts in their field?

    No, not really. Sanjay Gupta on CNN expressed similar concerns as I did.


  • #5207
    ACitizenErased
    Registered Users, Registered Users 2 Posts: 11,750 ✭✭✭✭ACitizenErased


    Based on the 90% rate and the 92 infections I think approximately 85 of the infections were in the placebo group


  • #5208
    odyssey06
    Registered Users, Registered Users 2 Posts: 35,496 ✭✭✭✭odyssey06


    10000maniacs wrote: »
    Aren't you the smug one?
    It's you that ain't grasping it. It all depends what type of vaccine it is. And what stage the virus is at in your system.
    And I meant giving the virus to the subject after the vaccine had been delivered.
    No need to be so arrogant in your replies.

    Pot. Kettle. Black.

    You think it would have been better to skip this phase and go straight to challenge trials?
    Can you give us a timeline on regulatory approval for skipping this phase of the trial and running challenge trials instead - if apparently you think it a better solution.

    The number of ppl that would be enrolled in a challenge trial would be a fraction of the current phase.

    "To follow knowledge like a sinking star..." (Tennyson's Ulysses)



  • #5209
    begbysback
    Closed Accounts Posts: 2,910 ✭✭✭begbysback


    Is it too late to buy Pfizer shares?


  • #5210
    10000maniacs
    Registered Users, Registered Users 2 Posts: 5,589 ✭✭✭10000maniacs


    odyssey06 wrote: »
    Pot. Kettle. Black.

    You think it would have been better to skip this phase and go straight to challenge trials?
    Can you give us a timeline on regulatory approval for skipping this phase of the trial and running challenge trials instead - if apparently you think it a better solution.

    The number of ppl that would be enrolled in a challenge trial would be a fraction of the current phase.

    All I really said was wait for the scientific report on what Pfizer are actually doing to get these figures. And that's all Dr Sanjay Gupta said too on CNN.


  • #5211
    ShineOn7
    Closed Accounts Posts: 4,550 ✭✭✭ShineOn7


    begbysback wrote: »
    Is it too late to buy Pfizer shares?

    They're only up 10% so far with three hours trading left in New York

    But perhaps a lot of their pricing was already built in over the last couple of months when they were looking strong to get there first


  • Advertisement
  • #5212
    timsey tiger
    Registered Users, Registered Users 2 Posts: 1,768 ✭✭✭timsey tiger


    begbysback wrote: »
    Is it too late to buy Pfizer shares?

    One could buy moderna shares, they droped on this news, but if they come up with the goods presently they should rebound.

    This obviously is not advice and none should be taken from anonomous losers on the internet.


  • #5213
    timsey tiger
    Registered Users, Registered Users 2 Posts: 1,768 ✭✭✭timsey tiger


    10000maniacs wrote: »
    A better solution would be to 50/50 split the vaccine and placebo to people in vulnerable groups.
    And another 50/50 split to random people with the virus.

    the split is not 50/50 morelike 2/3rds 1/3rd vaccine/placebo.

    You also would need to take in how long each individual was "exposed to risk" as some will have gotten the jab maybe twice as long as others who got it later and possibly even covid19 prevalence in the community where the individual lived.


  • #5214
    brisan
    Registered Users, Registered Users 2 Posts: 2,242 ✭✭✭brisan


    timsey tiger wrote: »
    One could buy moderna shares, they droped on this news, but if they come up with the goods presently they should rebound.

    This obviously is not advice and none should be taken from anonomous losers on the internet.

    Bit late now but I know 2 lads who bought 2k each worth of Ryanair shares in June
    Sitting pretty now


  • #5215
    Beasty
    Administrators, Social & Fun Moderators, Sports Moderators Posts: 78,458 Admin ✭✭✭✭✭Beasty


    Threads merged


  • #5216
    begbysback
    Closed Accounts Posts: 2,910 ✭✭✭begbysback


    timsey tiger wrote: »
    One could buy moderna shares, they droped on this news, but if they come up with the goods presently they should rebound.

    This obviously is not advice and none should be taken from anonomous losers on the internet.
    Don’t worry, I never take financial advice from someone who can’t spell anonymous :)


  • #5217
    odyssey06
    Registered Users, Registered Users 2 Posts: 35,496 ✭✭✭✭odyssey06


    10000maniacs wrote: »
    All I really said was wait for the scientific report on what Pfizer are actually doing to get these figures. And that's all Dr Sanjay Gupta said too on CNN.

    At no point did Dr Sanjay Gupta said they should have run challenge trials though.
    Questions about age range of participants, symptom tracking etc are of course important.

    "To follow knowledge like a sinking star..." (Tennyson's Ulysses)



  • #5218
    10000maniacs
    Registered Users, Registered Users 2 Posts: 5,589 ✭✭✭10000maniacs


    odyssey06 wrote: »
    At no point did Dr Sanjay Gupta said they should have run challenge trials though.
    Questions about age range of participants, symptom tracking etc are of course important.
    Challenge trials was my suggestion, but Gupta said that the target was the vulnerable population anyway.

    Here's what Dr. Gupta actually said today.
    Firstly this is good news. 90% effective! Give people the vaccine and give people placebo and see how effectively it works.
    But if the question is how effective is it in preventing people from getting sick who are infected, its a good question. 80% of people recover from this virus anyway with no symptoms or minimal symptoms. So it's this vulnerable population, how well will it work for them? How likely will it prevent them from getting sick? How long does it last? These are still unanswered questions. Is the vaccine going to be a yearly thing? If it's two shots, how long after you get the second shot will you have immunity? An entire season?
    (


  • #5219
    normanoffside
    Registered Users, Registered Users 2 Posts: 10,229 ✭✭✭✭normanoffside


    CIARAN_BOYLE wrote: »
    It's 90% on a group of 94 (confirmed cases of covid) among the 43000.

    Also its not that 90% lived and 10% died.

    Rather than the people involved in a trial are divided into 2 randomly. Half given the vaccine and half given a placebo.

    Roughly 85 people in the placebo group have gotten covid compared to roughly 9 in the vaccinated group. They suggest this means that 90% of the people from the vaccinated group did not get covid because of the vaccine.

    Didn't the Chinese report 100% efficacy?
    They said that of a group of Chinese workers in Huawei in Mexico 80 something got infected in an office but none of the 90+ who'd been vaccinated had been infected.


  • #5220
    Sam Hain
    Registered Users, Registered Users 2 Posts: 1,317 ✭✭✭Sam Hain


    MerlinSouthDub wrote: »
    Booked my flights for next summer when I heard the vaccine news :)

    A simpletons chain of reaction.


  • Advertisement
  • #5221
    Cork2021
    Registered Users, Registered Users 2 Posts: 2,420 ✭✭✭Cork2021


    Well this escalated quickly!!

    I let out a serious sigh of relief when I saw this.
    I know it’ll take time and a few more vaccines to come but to know there’s actually light at the end of this is unreal!! Hopefully be able to stay with my wife come March when our second baby arrives! Not just the birth!!!


This discussion has been closed.
Advertisement