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COVID-19: Vaccine/antidote and testing procedures Megathread [Mod Warning - Post #1]

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  • Closed Accounts Posts: 40,061 ✭✭✭✭Harry Palmr


    Some say children should be among the first to get this as they are almost all symptomatic.


  • Closed Accounts Posts: 4,550 ✭✭✭ShineOn7


    Gael23 wrote: »
    Would hope a little quicker than Q3 for at risk groups


    True

    Perhaps they'll combine the over 70s with them in Q2

    A week or so ago someone here posted the UK's proposed order of who gets it and in what order

    Would be interested in seeing it again


  • Registered Users, Registered Users 2 Posts: 5,977 ✭✭✭Russman


    ShineOn7 wrote: »
    I'm cautiously happy with this news, cautiously because the HSE are a national embarresment

    Probable rollout for Ireland timeline?

    2021

    Q1 - Frontline workers
    Q2 - Over 70s
    Q3 - Those with serious underlying symptoms
    Q4 - Everyone else

    Plus we only need a 50/60% uptake on it don't we?

    Leaving aside the mess the HSE will make of it, how many front line workers are there ish ? I genuinely don't know. I'd have thought a couple of those quarters above would be rolled into one and Q3 would be the end. Pure speculation obviously.


  • Banned (with Prison Access) Posts: 220 ✭✭holdyerhorses


    Some say children should be among the first to get this as they are almost all symptomatic.

    No point in vaccinating the kids if the vulnerable are vaccinated.


  • Registered Users, Registered Users 2 Posts: 3,789 ✭✭✭snotboogie


    Gael23 wrote: »
    Even so 1.3bn vaccines equals 650million people. That’s only 10% of the world’s population.
    Or can they licence the recipe out to other producers to further ramp up supply?

    Pfizer vaccine wont ever see China or huge swarths of Asia and Africa that will go for the Chinese vaccines.


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  • Registered Users, Registered Users 2 Posts: 1,627 ✭✭✭MerlinSouthDub



    I'm just surprised he didn't claim the news had been deliberately held back to stop him being re-elected.


  • Registered Users, Registered Users 2 Posts: 5,977 ✭✭✭Russman


    I stupidly just read the article and comments in The Journal!

    'Keep it'
    'Who's going to be the Guiney pigs?'
    'The sheep will take it'
    'So if we vaccinated all over Ireland only 490,000 people would get Covid/'

    The same ones protesting about restrictions will be protesting about this next!

    Don't ever do that :D:D, no good can come of it


  • Closed Accounts Posts: 4,550 ✭✭✭ShineOn7


    If the HSE & Dept of health haven't got some sort of plan in place then heads should roll. They'll need defence forces logistics to give them help with it probably


    They should roll but likely won't

    Paul Reid should be in politics with how many bullets he's dodged


  • Registered Users, Registered Users 2 Posts: 12,149 ✭✭✭✭Gael23


    Paul Reid should be sacked if they make a mess of it


  • Registered Users, Registered Users 2 Posts: 6,054 ✭✭✭D.Q


    I stupidly just read the article and comments in The Journal!

    'Keep it'
    'Who's going to be the Guiney pigs?'
    'The sheep will take it'
    'So if we vaccinated all over Ireland only 490,000 people would get Covid/'

    The same ones protesting about restrictions will be protesting about this next!

    Please isolate for 14 days


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  • Registered Users, Registered Users 2 Posts: 2,462 ✭✭✭landofthetree


    If the HSE & Dept of health haven't got some sort of plan in place then heads should roll. They'll need defence forces logistics to give them help with it probably

    Germany has already started.


    https://www.thelocal.de/20201023/germany-prepares-for-60-coronavirus-vaccination-centres

    German daily Bild said the federal Health Ministry has asked the country's 16 state governments to provide the addresses of potential vaccination centres by November 10th.

    According to the report, a total of 60 centres are to be established nationwide. The vaccination centres are necessary to guarantee the effectiveness of the vaccine, the reports says. The vaccine will have to be kept cool at minus 78C, but many medical practices lack the necessary efficient cooling devices.


  • Registered Users, Registered Users 2 Posts: 5,977 ✭✭✭Russman


    Germany has already started.


    https://www.thelocal.de/20201023/germany-prepares-for-60-coronavirus-vaccination-centres

    German daily Bild said the federal Health Ministry has asked the country's 16 state governments to provide the addresses of potential vaccination centres by November 10th.

    According to the report, a total of 60 centres are to be established nationwide. The vaccination centres are necessary to guarantee the effectiveness of the vaccine, the reports says. The vaccine will have to be kept cool at minus 78C, but many medical practices lack the necessary efficient cooling devices.

    60 centres in somewhere the size of Germany, what would that equate to here I wonder ? Provincial centres maybe ? Given the specific temperature requirement.


  • Posts: 17,728 ✭✭✭✭ [Deleted User]


    ShineOn7 wrote: »
    I'm cautiously happy with this news, cautiously because the HSE are a national embarresment

    Probable rollout for Ireland timeline?

    2021

    Q1 - Frontline workers
    Q2 - Over 70s
    Q3 - Those with serious underlying symptoms
    Q4 - Everyone else

    Plus we only need a 50/60% uptake on it don't we?

    They reckon 1.3 billion doses in 2021, the World has 7.8 billions....... I doubt we'll be given enough to cover everyone.


  • Registered Users, Registered Users 2 Posts: 2,004 ✭✭✭Hmmzis


    Gael23 wrote: »
    Is it looking like it gives Sterlising immunity?

    Waiting for Hmmzis analysis if this develoment

    Not enough data to tell that, but even if they just went with the primary outcome No.1 which is to prevent disease (confirmed by PCR) then it's a massive win no matter how you look at it.

    Once they publish the data we'll know for sure what the exact outcomes are.

    Another thing we would gain is the correlate of efficacy when compared to the NHP challenge trials. This would be another huge data set to have when working on subsequent 100% effective vaccines.

    Given this result from Pfizer/BNT, I would sort of be leaning for Monderna to do a bit better, J&J similar and Novavax to knock it out of the park. AZ/Oxford might come near it even with the single shot in the younger population, prime-boost might do a bit better actually (all populations) than Pfizer/BNT.


  • Registered Users, Registered Users 2 Posts: 13,848 ✭✭✭✭thebaz


    In such a horrific year , all the fear and anxiety back in March how good it is to announce a Vaccine that seams 90% effective - first real good news story on Covid this year - given what happened at weekeend - been a pretty good few days .
    https://www.bbc.com/news/health-54873105


  • Banned (with Prison Access) Posts: 220 ✭✭holdyerhorses


    * Someone that knows better *

    Is 94 enough of a sample size to be able to say this is working?


  • Registered Users, Registered Users 2 Posts: 2,462 ✭✭✭landofthetree


    https://mobile.twitter.com/Steven_Swinford/status/1325776285860245504


    Britain has ordered 40m doses of Pfizer vaccine, including 10m due by end of year if it gets regulatory approval

    This is who gets it:

    1. Care home residents & staff
    2. 80+
    3. 75+
    4. 70+
    5. 65+
    6. High risk adults under 65
    7. Moderate risk adults under 65
    8. 60+
    9. 55+
    10. 50+


  • Registered Users, Registered Users 2 Posts: 11,750 ✭✭✭✭ACitizenErased


    Augeo wrote: »
    They reckon 1.3 billion doses in 2021, the World has 7.8 billions....... I doubt we'll be given enough to cover everyone.
    And then add:
    J&J
    Moderna
    Astrazeneca
    CanSinoBIO
    Novavax
    Sinopharm
    Sinovac
    Bharat Biotech


    And...
    Zydus
    Curevac
    Imperial College London
    Osaka University
    Arcturus
    Anhui Zhifei Longcom
    Finlay Vaccine Institute


    And that's me being conservative


  • Closed Accounts Posts: 4,550 ✭✭✭ShineOn7


    Augeo wrote: »
    They reckon 1.3 billion doses in 2021, the World has 7.8 billions....... I doubt we'll be given enough to cover everyone.


    Plus two doses of it are needed

    But! Some regions of the world have pretty much Zero Covid anyway or are heading that way. New Zealand and Oz for example

    South East Asia have stamped on it so hard that case numbers there are tiny compared to the EU and America. And haven't parts of Africa got a very small amount of cases?

    So I'm guessing all that will play into it too

    Who knows at this stage eh?


  • Posts: 17,728 ✭✭✭✭ [Deleted User]


    And then add:
    J&J
    Moderna
    Astrazeneca
    CanSinoBIO
    Novavax
    Sinopharm
    Sinovac
    Bharat Biotech


    And...
    Zydus
    Curevac
    Imperial College London
    Osaka University
    Arcturus
    Anhui Zhifei Longcom
    Finlay Vaccine Institute


    And that's me being conservative

    They don't have vaccines as yet


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  • Registered Users, Registered Users 2 Posts: 11,750 ✭✭✭✭ACitizenErased


    Augeo wrote: »
    They don't have vaccines as yet
    All of the first group are in the exact same phase as Pfizer.


  • Registered Users, Registered Users 2 Posts: 11,750 ✭✭✭✭ACitizenErased




  • Registered Users, Registered Users 2 Posts: 575 ✭✭✭eastie17


    In the films, isnt it the injection of the vaccine stage of whatever pandemic there was when we start showing zombie like behavior, eating eachother and so on?

    Just in case we all get too optimistic, expect George Lee to start talking about this soon in case anyone gets too happy.


  • Posts: 17,728 ✭✭✭✭ [Deleted User]


    And then add:
    J&J
    Moderna
    Astrazeneca
    CanSinoBIO
    Novavax
    Sinopharm
    Sinovac
    Bharat Biotech


    And...
    Zydus
    Curevac
    Imperial College London
    Osaka University
    Arcturus
    Anhui Zhifei Longcom
    Finlay Vaccine Institute


    And that's me being conservative
    All of the first group are in the exact same phase as Pfizer.

    My reply was to someone querying how the HSE would cope with managing the roll out of the vaccine....... I pointed out they won't get enough to vaccinate the population in a single year.

    I'll go further, you don't have to vaccinate the entire population if a vaccine is 90% effective :)

    J&J may well be at the same phase but there's was on hold for a period...... same phase isn't at all informative in the vaccine game. It's a results business.


  • Closed Accounts Posts: 4,550 ✭✭✭ShineOn7


    American markets haven't opened yet have they?

    Pfizer share holders today ...

    AromaticCarelessBackswimmer-small.gif


  • Posts: 0 [Deleted User]


    * Someone that knows better *

    Is 94 enough of a sample size to be able to say this is working?

    My background is pharmacology, and used to work in regulatory affairs. My knowledge of vaccine trials is limited but as far as I can tell this is a somewhat spectacular result for a first vaccine. Sample size is more than adequate.


  • Registered Users, Registered Users 2 Posts: 13,848 ✭✭✭✭thebaz


    What makes me happier , is hopefully all the divisions in society , as could be seen here , will hopefully come together , and we can start living life together again - the extremists will never be happy I know.


  • Registered Users, Registered Users 2 Posts: 894 ✭✭✭cian68


    ShineOn7 wrote: »
    American markets haven't opened yet have they?

    Zoom shares have gone down 5.5% and cinemas and airlines are going up


  • Registered Users, Registered Users 2 Posts: 5,977 ✭✭✭Russman


    Augeo wrote: »
    My reply was to someone querying how the HSE would cope with managing the roll out of the vaccine....... I pointed out they won't get enough to vaccinate the population in a single year.

    I'll go further, you don't have to vaccinate the entire population if a vaccine is 90% effective :)

    J&J may well be at the same phase but there's was on hold for a period...... same phase isn't at all informative in the vaccine game. It's a results business.

    They might go close if Oxford and J&J come through too though, no ?


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  • Registered Users, Registered Users 2 Posts: 41,019 ✭✭✭✭Itssoeasy


    ShineOn7 wrote: »
    American markets haven't opened yet have they?

    Pfizer share holders today ...

    AromaticCarelessBackswimmer-small.gif

    No not yet.

    It’s Finally a ray of light and what’s been a mess of a year in many ways and hopefully it all goes well. I expected myself to be happier but I’m being over cautious.


This discussion has been closed.
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