COVID-19: Vaccine/antidote and testing procedures Megathread [Mod Warning - Post #1]

Gael23 wrote: »

Would hope a little quicker than Q3 for at risk groups

True

Perhaps they'll combine the over 70s with them in Q2

A week or so ago someone here posted the UK's proposed order of who gets it and in what order

Would be interested in seeing it again

ShineOn7 wrote: »

I'm cautiously happy with this news, cautiously because the HSE are a national embarresment

Probable rollout for Ireland timeline?

2021

Q1 - Frontline workers
Q2 - Over 70s
Q3 - Those with serious underlying symptoms
Q4 - Everyone else

Plus we only need a 50/60% uptake on it don't we?

Leaving aside the mess the HSE will make of it, how many front line workers are there ish ? I genuinely don't know. I'd have thought a couple of those quarters above would be rolled into one and Q3 would be the end. Pure speculation obviously.

snotboogie

Gael23 wrote: »

Even so 1.3bn vaccines equals 650million people. That’s only 10% of the world’s population.
Or can they licence the recipe out to other producers to further ramp up supply?

Pfizer vaccine wont ever see China or huge swarths of Asia and Africa that will go for the Chinese vaccines.

holdyerhorses

Harry Palmr wrote: »

Some say children should be among the first to get this as they are almost all symptomatic.

No point in vaccinating the kids if the vulnerable are vaccinated.

MerlinSouthDub

stephenjmcd wrote: »

Didn't take long

https://twitter.com/realDonaldTrump/status/1325778096151203843?s=19

I'm just surprised he didn't claim the news had been deliberately held back to stop him being re-elected.

stephenjmcd wrote: »

If the HSE & Dept of health haven't got some sort of plan in place then heads should roll. They'll need defence forces logistics to give them help with it probably

They should roll but likely won't

Paul Reid should be in politics with how many bullets he's dodged

daydorunrun wrote: »

I stupidly just read the article and comments in The Journal!

'Keep it'
'Who's going to be the Guiney pigs?'
'The sheep will take it'
'So if we vaccinated all over Ireland only 490,000 people would get Covid/'

The same ones protesting about restrictions will be protesting about this next!

Don't ever do that

:D, no good can come of it

Gael23

Paul Reid should be sacked if they make a mess of it

D.Q

daydorunrun wrote: »

I stupidly just read the article and comments in The Journal!

'Keep it'
'Who's going to be the Guiney pigs?'
'The sheep will take it'
'So if we vaccinated all over Ireland only 490,000 people would get Covid/'

The same ones protesting about restrictions will be protesting about this next!

Please isolate for 14 days

landofthetree

stephenjmcd wrote: »

If the HSE & Dept of health haven't got some sort of plan in place then heads should roll. They'll need defence forces logistics to give them help with it probably

Germany has already started.

https://www.thelocal.de/20201023/germany-prepares-for-60-coronavirus-vaccination-centres

German daily Bild said the federal Health Ministry has asked the country's 16 state governments to provide the addresses of potential vaccination centres by November 10th.

According to the report, a total of 60 centres are to be established nationwide. The vaccination centres are necessary to guarantee the effectiveness of the vaccine, the reports says. The vaccine will have to be kept cool at minus 78C, but many medical practices lack the necessary efficient cooling devices.

landofthetree wrote: »

Germany has already started.

https://www.thelocal.de/20201023/germany-prepares-for-60-coronavirus-vaccination-centres

German daily Bild said the federal Health Ministry has asked the country's 16 state governments to provide the addresses of potential vaccination centres by November 10th.

According to the report, a total of 60 centres are to be established nationwide. The vaccination centres are necessary to guarantee the effectiveness of the vaccine, the reports says. The vaccine will have to be kept cool at minus 78C, but many medical practices lack the necessary efficient cooling devices.

60 centres in somewhere the size of Germany, what would that equate to here I wonder ? Provincial centres maybe ? Given the specific temperature requirement.

ShineOn7 wrote: »

I'm cautiously happy with this news, cautiously because the HSE are a national embarresment

Probable rollout for Ireland timeline?

2021

Q1 - Frontline workers
Q2 - Over 70s
Q3 - Those with serious underlying symptoms
Q4 - Everyone else

Plus we only need a 50/60% uptake on it don't we?

They reckon 1.3 billion doses in 2021, the World has 7.8 billions....... I doubt we'll be given enough to cover everyone.

Hmmzis

Gael23 wrote: »

Is it looking like it gives Sterlising immunity?

Waiting for Hmmzis analysis if this develoment

Not enough data to tell that, but even if they just went with the primary outcome No.1 which is to prevent disease (confirmed by PCR) then it's a massive win no matter how you look at it.

Once they publish the data we'll know for sure what the exact outcomes are.

Another thing we would gain is the correlate of efficacy when compared to the NHP challenge trials. This would be another huge data set to have when working on subsequent 100% effective vaccines.

Given this result from Pfizer/BNT, I would sort of be leaning for Monderna to do a bit better, J&J similar and Novavax to knock it out of the park. AZ/Oxford might come near it even with the single shot in the younger population, prime-boost might do a bit better actually (all populations) than Pfizer/BNT.

thebaz

In such a horrific year , all the fear and anxiety back in March how good it is to announce a Vaccine that seams 90% effective - first real good news story on Covid this year - given what happened at weekeend - been a pretty good few days .
https://www.bbc.com/news/health-54873105

holdyerhorses

* Someone that knows better *

Is 94 enough of a sample size to be able to say this is working?

landofthetree

https://mobile.twitter.com/Steven_Swinford/status/1325776285860245504

Britain has ordered 40m doses of Pfizer vaccine, including 10m due by end of year if it gets regulatory approval

This is who gets it:

1. Care home residents & staff
2. 80+
3. 75+
4. 70+
5. 65+
6. High risk adults under 65
7. Moderate risk adults under 65
8. 60+
9. 55+
10. 50+

ACitizenErased

Augeo wrote: »

They reckon 1.3 billion doses in 2021, the World has 7.8 billions....... I doubt we'll be given enough to cover everyone.

And then add:
J&J
Moderna
Astrazeneca
CanSinoBIO
Novavax
Sinopharm
Sinovac
Bharat Biotech

And...
Zydus
Curevac
Imperial College London
Osaka University
Arcturus
Anhui Zhifei Longcom
Finlay Vaccine Institute

And that's me being conservative

Augeo wrote: »

They reckon 1.3 billion doses in 2021, the World has 7.8 billions....... I doubt we'll be given enough to cover everyone.

Plus two doses of it are needed

But! Some regions of the world have pretty much Zero Covid anyway or are heading that way. New Zealand and Oz for example

South East Asia have stamped on it so hard that case numbers there are tiny compared to the EU and America. And haven't parts of Africa got a very small amount of cases?

So I'm guessing all that will play into it too

Who knows at this stage eh?

ACitizenErased wrote: »

And then add:
J&J
Moderna
Astrazeneca
CanSinoBIO
Novavax
Sinopharm
Sinovac
Bharat Biotech

And...
Zydus
Curevac
Imperial College London
Osaka University
Arcturus
Anhui Zhifei Longcom
Finlay Vaccine Institute

And that's me being conservative

They don't have vaccines as yet

ACitizenErased

Augeo wrote: »

They don't have vaccines as yet

All of the first group are in the exact same phase as Pfizer.

ACitizenErased

https://www.boards.ie/vbulletin/showthread.php?t=2058062347&page=330 full thread on it here as an FYI

eastie17

In the films, isnt it the injection of the vaccine stage of whatever pandemic there was when we start showing zombie like behavior, eating eachother and so on?

Just in case we all get too optimistic, expect George Lee to start talking about this soon in case anyone gets too happy.

ACitizenErased wrote: »

And then add:
J&J
Moderna
Astrazeneca
CanSinoBIO
Novavax
Sinopharm
Sinovac
Bharat Biotech

And...
Zydus
Curevac
Imperial College London
Osaka University
Arcturus
Anhui Zhifei Longcom
Finlay Vaccine Institute

And that's me being conservative

ACitizenErased wrote: »

All of the first group are in the exact same phase as Pfizer.

My reply was to someone querying how the HSE would cope with managing the roll out of the vaccine....... I pointed out they won't get enough to vaccinate the population in a single year.

I'll go further, you don't have to vaccinate the entire population if a vaccine is 90% effective

J&J may well be at the same phase but there's was on hold for a period...... same phase isn't at all informative in the vaccine game. It's a results business.

American markets haven't opened yet have they?

Pfizer share holders today ...

holdyerhorses wrote: »

* Someone that knows better *

Is 94 enough of a sample size to be able to say this is working?

My background is pharmacology, and used to work in regulatory affairs. My knowledge of vaccine trials is limited but as far as I can tell this is a somewhat spectacular result for a first vaccine. Sample size is more than adequate.

thebaz

What makes me happier , is hopefully all the divisions in society , as could be seen here , will hopefully come together , and we can start living life together again - the extremists will never be happy I know.

cian68

ShineOn7 wrote: »

American markets haven't opened yet have they?

Zoom shares have gone down 5.5% and cinemas and airlines are going up

Augeo wrote: »

My reply was to someone querying how the HSE would cope with managing the roll out of the vaccine....... I pointed out they won't get enough to vaccinate the population in a single year.

I'll go further, you don't have to vaccinate the entire population if a vaccine is 90% effective

J&J may well be at the same phase but there's was on hold for a period...... same phase isn't at all informative in the vaccine game. It's a results business.

They might go close if Oxford and J&J come through too though, no ?

Itssoeasy

ShineOn7 wrote: »

American markets haven't opened yet have they?

Pfizer share holders today ...

No not yet.

It’s Finally a ray of light and what’s been a mess of a year in many ways and hopefully it all goes well. I expected myself to be happier but I’m being over cautious.