COVID-19: Vaccine/antidote and testing procedures Megathread [Mod Warning - Post #1]

ACitizenErased wrote: »

There's quite the proportion on this website who refuse to acknowledge potential vaccines and predict on-going lockdowns until 2022-2023.

Ahh thought you were refferring to those pushing for lockdowns now.

Either way, we're all gonna be vaccinated up to our eyeballs and we'll run free, naked and care-free, like a cow who's just been let outside after a long winter..

... no? Just me?

Deleted User wrote: »

Well, not only do manufacturers need to get FDA approval to market a drug in the US, they also have to be able to demonstrate compliance with Title 21 Chapter 1 of the Code of Federal Regulations and the executives with responsibility to ensure compliance are criminally responsible if they authorise release of a product which subsequently causes harm and they have not satisfied the requirements of the federal code.

So even if Trump was to pressurise the FDA into early approval before requirements were met, reputable manufactures would be reluctant to release, knowing they had not fulfilled the criteria.

pretty sure vaccine manufacturers carry no liability risk in the states according to the PREP act:

https://www.federalregister.gov/documents/2020/04/15/2020-08040/amendment-to-declaration-under-the-public-readiness-and-emergency-preparedness-act-for-medical

funnydoggy wrote: »

How does this work, it being so close to the end of the trial?

Confuses me. Thanks hmmm

From what I've read, it's best to think of the trials as having no fixed date for when they will end.

It's likely we will get data from the initial 30,000 people hopefully by the end of the year. The regulators on the back of that might decide they will allow the vaccine to be given to certain high-risk groups. But the regulators will also likely tell the Pfizers of this world to keep monitoring the 30,000, and include a few more groups (e.g. children), and then make another decision later in 2020 as to whether they will allow the vaccine to be widely deployed (and who gets it).

By mid-2021, they will have nearly a years worth of data on the initial 30,000 people, and another couple of million people will have received the initial release of the vaccine.

JTMan wrote: »

Update on the Chinese vaccines from the WSJ here (paywall).

- China National Biotec Group Co., a division of state-owned Sinopharm that is developing two Covid-19 vaccines, is giving them free to Chinese students planning to study abroad. Apply via website.
- 481,613 people had already taken the Sinopharm vaccines while an additional 93,653 had applied for them.
- Four of China’s vaccines are in the last phase of clinical testing on tens of thousands volunteers, with some of its drugmakers expected to publish preliminary results in the coming weeks.
- Some criticise China for "moving too fast".

They are pretty big numbers

hmmm wrote: »

From what I've read, it's best to think of the trials as having no fixed date for when they will end.

It's likely we will get data from the initial 30,000 people hopefully by the end of the year. The regulators on the back of that might decide they will allow the vaccine to be given to certain high-risk groups. But the regulators will also likely tell the Pfizers of this world to keep monitoring the 30,000, and include a few more groups (e.g. children), and then make another decision later in 2020 as to whether they will allow the vaccine to be widely deployed (and who gets it).

By mid-2021, they will have nearly a years worth of data on the initial 30,000 people, and another couple of million people will have received the initial release of the vaccine.

Perfectly explained, go raibh mile!

Gael23 wrote: »

So it will be late 2021 then

By the time young healthy people get a vaccine, yeah of course. Bottom of the queue

dominatinMC wrote: »

But by then, we'll all be back going to matches, concerts, pubs, restaurants etc. as most young people (bar those with underlying conditions) will be willing to take the risk and get on with living - as opposed to existing, which is the current status quo.

As has been said before, you don't need everyone vaccinated to break transmission.
When vulnerable groups are vaccinated then you can take the foot off restrictions and continue to unwind

hmmm wrote: »

We're going to face problems with community spread and hospital capacity until we get the tools like rapid testing, vaccines & treatments. We're unlikely to be reopening pubs, nightclubs, concerts until those tools are deployed.

I'm guessing that rapid testing will be the first thing to make a big impact, with vaccines following a few months later. The manufacturing capacity for treatments (e.g. Regeneron/Lilly) appears to be lagging where we'd like it to be, but it will catch up in time.

Well the HSE seem incapable of getting testing right so not convinced rapid testing will happen

Gael23 wrote: »

Well the HSE seem incapable of getting testing right so not convinced rapid testing will happen

If you want to throw out inaccurate crap go ahead.

If you would prefer to give fair criticism critise the contact tracing rather than the testing.

We should send an email to the EMA and tell em hurry up a tad, could do with it now