COVID-19: Vaccine/antidote and testing procedures Megathread [Mod Warning - Post #1]

iguana · 05-09-2020 10:23AM

What do we think the Moderna insider share sell off means? The obvious assumption is insider information that the MRNA-1273 vaccine isn't doing as well in Phase 3 as hoped.

https://www.forbes.com/sites/jimcollins/2020/09/04/why-are-moderna-insiders-selling-so-many-shares/#e06174d5dc0d

Gael23 · 05-09-2020 02:16PM

iguana wrote: »

What do we think the Moderna insider share sell off means? The obvious assumption is insider information that the MRNA-1273 vaccine isn't doing as well in Phase 3 as hoped.

https://www.forbes.com/sites/jimcollins/2020/09/04/why-are-moderna-insiders-selling-so-many-shares/#e06174d5dc0d

If that does turn out to be the case then there does need to be a plan to stop the US intercepting deliveries of the oxford vaccine in transit

timsey tiger · 05-09-2020 02:46PM

iguana wrote: »

What do we think the Moderna insider share sell off means? The obvious assumption is insider information that the MRNA-1273 vaccine isn't doing as well in Phase 3 as hoped.

https://www.forbes.com/sites/jimcollins/2020/09/04/why-are-moderna-insiders-selling-so-many-shares/#e06174d5dc0d

Answer could be, right there in second last paragraph of article, without any illegal insider trading.

Covid-19 vaccine will be just a one off payday. After the preorders are fulfilled there will be competition between a number of company's with competing vaccines. Projected profits built in to share price, by overexcited investors prob. overestimate potential profits and insiders are more aware of this than market.

Gael23 · 05-09-2020 08:47PM

This is an interesting article although it paints a pessimistic view https://www.google.ie/amp/s/www.irishtimes.com/news/science/coronavirus-early-vaccines-may-help-but-not-halt-the-pandemic-1.4339241%3fmode=amp

Happydays2020 · 05-09-2020 08:52PM

Masala wrote: »

Today being Paddy Day 2020... when do you think we will have a ‘flu jab’ / pill / syrup that we can take to make us immune/ les likely to catch this 19 virus?.

paddy’s Day 2024

Micky 32 · 05-09-2020 08:52PM

Gael23 wrote: »

This is an interesting article although it paints a pessimistic view https://www.google.ie/amp/s/www.irishtimes.com/news/science/coronavirus-early-vaccines-may-help-but-not-halt-the-pandemic-1.4339241%3fmode=amp

Well sure if that’s the case we may have to accept the rest of our lives are going to be crap.We’ll have nothing to look forward to.

Beasty · 05-09-2020 09:03PM

Threads merged

timsey tiger · 05-09-2020 10:47PM

Gael23 wrote: »

This is an interesting article although it paints a pessimistic view https://www.google.ie/amp/s/www.irishtimes.com/news/science/coronavirus-early-vaccines-may-help-but-not-halt-the-pandemic-1.4339241%3fmode=amp

Too much what if-ery. What if we have a vaccine protocol with the 5 best vaccines developed, giving 99.99% protection?

Marhay70 · 06-09-2020 10:55AM

Gael23 wrote: »

This is an interesting article although it paints a pessimistic view https://www.google.ie/amp/s/www.irishtimes.com/news/science/coronavirus-early-vaccines-may-help-but-not-halt-the-pandemic-1.4339241%3fmode=amp

It's a worst case scenario. The virus is spreading mainly among younger adults at the moment so if we can eliminate that source with a vaccine then surely the older generations will have less exposure to the virus anyway.
It's not an ideal situation but we have to walk before we can run.
I am in my seventies and receive the flu vaccine every year, I assume at some stage somebody said the flu vaccine wouldn't work on this one or that. As it is, I don't mix in large crowds, I don't drink in packed pubs, I don't travel on public transport because there is none, so I generally do what I need to do anyway.

scooby77 · 06-09-2020 02:47PM

Saw interesting discussion on vaccines between professors during the week (either CNN or bloomberg, not sure)
They were very optimistic about safety of vaccines, as methods used tried and tested ( though they clarified even common, safe medicines can have adverse effects on a tiny minority)
However they agreed there were 3 main questions, which really only time can answer
1. How long will vaccine protect for, and will subsequent doses be effective?( touched on earlier here)
2. Assuming vaccines protects, could vaccinated person still spread virus?( as asymptomatic people seem to be effective spreaders)
3. Related to previous...will vaccine effectively protect in elderly and sick, and if not, and vaccinated people still spread, how protect elderly and sick.?
Important issues, but I agree that we really need time for definite answers.

hmmm · 06-09-2020 03:23PM

Great post scooby, fully agree.

This is a really interesting read about mRNA vaccines:

https://jamanetwork.com/journals/jama/fullarticle/2770485

"Experts said in interviews that if the technology pans out, the pandemic could help to usher in a new plug-and-play approach to vaccinology."

"Thanks to research beginning in 2002 on the severe acute respiratory syndrome coronavirus and then the Middle East respiratory syndrome coronavirus, which emerged a decade later, scientists knew to focus their initial attention on the novel coronavirus’ spike protein. "

"Weissman is trying to develop a more potent second-generation mRNA vaccine that protects with a single shot. He’s also set his sights on a universal coronavirus vaccine using the genetic platform. “We’ve had 3 coronavirus epidemics in the past 20 years,” he said. “The next time this happens, we’ll have a vaccine already made, ready to be shipped out and used very quickly to prevent the pandemic from taking over.”"

Hand in Your Pants · 06-09-2020 03:44PM

Can't believe all these morans saying they'll refuse the jab. Absolute morans. It's just a mask ffs

timsey tiger · 06-09-2020 03:49PM

Hand in Your Pants wrote: »

Can't believe all these morans saying they'll refuse the jab. Absolute morans. It's just a mask ffs

Are these the Sligo Morans or the Mayo Morans?

Capt'n Midnight · 06-09-2020 03:52PM

The common cold might offer some protection against flu and other viruses.

[URL="[url]https://news.yale.edu/2020/09/04/common-cold-combats-influenza[/url]"]Press release [/URL]

Paper. Yale. The Lancet Microbe.

In fact, the annual
autumn rhinovirus epidemic associated with school reentry
in the northern hemisphere might be a major factor
determining the timing and severity of the annual winter
inﬂuenza epidemic, an important cause of morbidity and
mortality every year.

CruelSummer · 06-09-2020 04:21PM

Ah yes, it's all good news on this thread. Nothing about any side effects or potential dangers being discussed, or why they are slowing down phase 3 trials of the Moderna vaccine...nothing about the fact that RNA vaccines have never been used before and are highly experimental.
So who is going to be first in line here to get their shot?

is_that_so · 06-09-2020 04:24PM

Hand in Your Pants wrote: »

Can't believe all these morans saying they'll refuse the jab. Absolute morans. It's just a mask ffs

I'm guessing you're in the wrong thread. It's moron, Moran is a surname!

is_that_so · 06-09-2020 04:25PM

CruelSummer wrote: »

Ah yes, it's all good news on this thread. Nothing about any side effects or potential dangers being discussed, or why they are slowing down phase 3 trials of the Moderna vaccine...nothing about the fact that RNA vaccines have never been used before and are highly experimental.
So who is going to be first in line here to get their shot?

We may not have a choice. It will probably be high risk, front line, others at risk, maybe kids and then gen pop in that order. Q3-Q4 of next year would be good.

alwald · 06-09-2020 05:10PM

CruelSummer wrote: »

So who is going to be first in line here to get their shot?

Looking at various polls in various countries the percentage of those willing to take the vaccine is between 30% to 70%.

I admire the research and effort behind it as it's unprecedented but I won't line up to take this vaccine.

Marhay70 · 06-09-2020 05:32PM

alwald wrote: »

Looking at various polls in various countries the percentage of those willing to take the vaccine is between 30% to 70%.

I admire the research and effort behind it as it's unprecedented but I won't line up to take this vaccine.

That's your choice. What is objected to on this thread is people who try to convince others not to take vaccines by spouting lies and bullsh*t.

landofthetree · 06-09-2020 05:34PM

alwald wrote: »

Looking at various polls in various countries the percentage of those willing to take the vaccine is between 30% to 70%.

I admire the research and effort behind it as it's unprecedented but I won't line up to take this vaccine.

No problem.

Just give out Covid cards with ID to those who have taken the vaccine.

You will need the card to go into educational institutions,cafes,restaurants,cinemas,sporting events etc.

mean gene · 06-09-2020 05:39PM

is_that_so wrote: »

I'm guessing you're in the wrong thread. It's moron, Moran is a surname!

what a moron ya man

alwald · 06-09-2020 06:22PM

landofthetree wrote: »

No problem.

Just give out Covid cards with ID to those who have taken the vaccine.

You will need the card to go into educational institutions,cafes,restaurants,cinemas,sporting events etc.

A lot of people here are fantasising about giving cards to those who took the vaccine, put a bracelet on those who didn't or even deny those who didn't any medical care in case they get sick. None of these will happen and it's quite certain that no EU country will make this vaccine mandatory or exclude those who didn't take it.

Deeper Blue · 06-09-2020 08:51PM

This was a great thread before the anti vaxxers started poisoning it with their nonsense

LessOutragePlz · 06-09-2020 08:57PM

El Sueño wrote: »

This was a great thread before the anti vaxxers started poisoning it with their nonsense

Is it possible to not want take a vaccine and not be an anti vaxxer, or are the 2 inseparable?

The only reason I ask is because I've been vaccinated as a child but I would be hesitant to take a covid 19 vaccine.

timsey tiger · 06-09-2020 09:52PM

LessOutragePlz wrote: »

Is it possible to not want take a vaccine and not be an anti vaxxer, or are the 2 inseparable?

The only reason I ask is because I've been vaccinated as a child but I would be hesitant to take a covid 19 vaccine.

Yes, you could just be a self centered misanthropic asshole, who is a low risk group, who couldn't be bothered to help society out, but still understand the science behind vaccines.

Marhay70 · 06-09-2020 10:01PM

timsey tiger wrote: »

Yes, you could just be a self centered misanthropic asshole, who is a low risk group, who couldn't be bothered to help society out, but still understand the science behind vaccines.

Bit harsh there Timsey, I'm sure he must like somebody.

timsey tiger · 06-09-2020 10:17PM

Marhay70 wrote: »

Bit harsh there Timsey, I'm sure he must like somebody.

LOL, I didn't say he was, that would get me a ban. I said "you could be ..."

LessOutragePlz · 06-09-2020 10:46PM

timsey tiger wrote: »

Yes, you could just be a self centered misanthropic asshole, who is a low risk group, who couldn't be bothered to help society out, but still understand the science behind vaccines.

Fair enough but, the fact that the vaccine producers are lobbying the EU for legal protection from any litigation that could result from the potential side effects for people that take the vaccine doesn't inspire my confidence in them.

"Covid-19 vaccine makers lobby EU for legal protection"

https://www.ft.com/content/12f7da5b-92c8-4050-bcea-e726b75eef4d

AstraZeneca has already secured exemptions from coronavirus vaccine liability claims in most countries.

https://uk.mobile.reuters.com/article/amp/idUKKCN24V2EN

I think it's fair to say that this stance from the vaccine producers will have a negative impact on the amount of people that would are willing to take the vaccine and pour fuel on the anti-vaxxers fire.

Hand in Your Pants · 06-09-2020 10:53PM

Saw some of these morans out protesting on Saturday, shuddup you selfish ejits, just wear the mask ffs, jab needs to be mandatory for these wreckless morans, otherwise no dole, no meds, no loans

Hmmzis · 06-09-2020 10:58PM

LessOutragePlz wrote: »

Is it possible to not want take a vaccine and not be an anti vaxxer, or are the 2 inseparable?

The only reason I ask is because I've been vaccinated as a child but I would be hesitant to take a covid 19 vaccine.

Just out of curiosity, are you concerned about any particular vaccine candidate or a particular platform of vaccines?

There are at least 30 individual candidates in human trials at this point in time and using about half a dozen platform types.

When it comes to vaccinating non-risk groups there will be an even bigger choice of types and manufacturers to chose from, including the current safety champions - sub-unit and VLP types.

COVID-19: Vaccine/antidote and testing procedures Megathread [Mod Warning - Post #1]

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