COVID-19: Vaccine/antidote and testing procedures Megathread [Mod Warning - Post #1]

irishgeo

ShineOn7 wrote: »

O'Neill is a populist gobshíte. Time after time he just says whatever gets the most attention and has flipped opinion several times on this since March



https://www.irishtimes.com/news/ireland/irish-news/reasons-to-be-optimistic-for-a-covid-19-vaccine-by-christmas-says-expert-1.4383970

I see he fails to mention that IF the Pfizer one happens by Christmas it'll still be Q4 next year before all in the EU have it if we follow the talked about timeline of:

• Q4 this year/Q1 next year - Frontline workers
• Q2 next year - Over 70s
• Q3 next year - Those with underlying symptoms
• Q4 next year - Er, everyone else?

It all feels like fantasy type hope at the moment with this vaccine

And I believe the theories going around this week that Pfizer's announcement was just to boost their stock price

You can't just say anything to boost your stock price. It's against all sorts of rules. Ask Elon musk.

D.Q

Probably a silly question, when they develop and start rolling out the vaccine, if you get get a positive test, can you take the vaccine as a cure? Or does it need to be pre infection haha

Hmmzis

D.Q wrote: »

Probably a silly question, when they develop and start rolling out the vaccine, if you get get a positive test, can you take the vaccine as a cure? Or does it need to be pre infection haha

The incubation period is too short for that I think. The median time to symptom onset is 5 days. To get a response from a vaccine it would take more time than that, usually a few weeks. Plus, most of the front runners are prime-boost regimen vaccines (J&J ia the only single shot candidate).

Micky 32

ACitizenErased wrote: »

The US are preparing for the majority of people to have been vaccinated by June next year.

According to all the experts on the other thread even if the vaccine is approved and distributed it’s not going to work. Apparently people are stiil going to get sick and die.

Le Bruise

Micky 32 wrote: »

According to all the experts on the other thread even if the vaccine is approved and distributed it’s not going to work. Apparently people are stiil going to get sick and die.

The negativity on the main thread is infuriating! So many seem to want to wallow in this pandemic for ever more. It’s also mad how many of my (non-boards) mates have no clue about any sort of vaccines, thinking this will go on indefinitely.....we can certainly blame RTE for that!

Gael23

Will the EU purchase be allocated on the basis of population?

Thierry12

Le Bruise wrote: »

The negativity on the main thread is infuriating! So many seem to want to wallow in this pandemic for ever more. It’s also mad how many of my (non-boards) mates have no clue about any sort of vaccines, thinking this will go on indefinitely.....we can certainly blame RTE for that!

Thank its pretty clear now the vaccines will work

Won't be sterilising or even 80% efficacy, but going to work very well overall

Some will get sick and die even with the vaccine, hopefully will be very rare but will happen

Gael23

Thierry12 wrote: »

Thank its pretty clear now the vaccines will work

Won't be sterilising or even 80% efficacy, but going to work very well overall

Some will get sick and die even with the vaccine, hopefully will be very rare but will happen

Is the fact that it won’t be sterilising a huge negative or is it not a big deal?

ACitizenErased

Gael23 wrote: »

Is the fact that it won’t be sterilising a huge negative or is it not a big deal?

If you can reduce serious disease by 80-90% then you can basically get back to normal

CIARAN_BOYLE

Gael23 wrote: »

Is the fact that it won’t be sterilising a huge negative or is it not a big deal?

A number of commentators have suggested that it will take til 2023 for second generation vaccines to emerge for life to return to normal. It is suggested that the vaccines will act more to reduce symptoms than to produce immunity for the majority. It is possible that it will provide genuine immunity for a minority (which would act to reduce the R number significantly).

They won't necessarily break the chain of transmission but rather ensure more asymptomatic cases and less hospitalisations, icu and death.

It's a major disappointment compared to to hopes but its a massive step from having nothing. If it for example halves the risk of icu admission we can sustain twice as many daily cases (if vaccinated) before the health service feels strain.

Here's a fairly readable article from 4 weeks ago.

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31976-0/fulltext

Thierry12

Gael23 wrote: »

Is the fact that it won’t be sterilising a huge negative or is it not a big deal?

Its a big negative if they are still contagious and get people sick, as we will have limited vaccine production for a while

Monkeys in the trials were contagious, they did get exposed to massive doses though so it might be rare for a human to be contagious and spread it to non vaccinated

Le Bruise

CIARAN_BOYLE wrote: »

A number of commentators have suggested that it will take til 2023 for second generation vaccines to emerge for life to return to normal. It is suggested that the vaccines will act more to reduce symptoms than to produce immunity for the majority. It is possible that it will provide genuine immunity for a minority (which would act to reduce the R number significantly).

They won't necessarily break the chain of transmission but rather ensure more asymptomatic cases and less hospitalisations, icu and death.

It's a major disappointment compared to to hopes but its a massive step from having nothing. If it for example halves the risk of icu admission we can sustain twice as many daily cases (if vaccinated) before the health service feels strain.

Here's a fairly readable article from 4 weeks ago.

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31976-0/fulltext

So no return to normal until 2023......that’s ok, if your idea of normal is a ‘mad max beyond thunderdome’ sort of reality?

ACitizenErased

Tbh lads being able to goto a shop without wearing a mask or being able to go to a football match with more than 200 people is enough of a return to normal for me

Le Bruise

ACitizenErased wrote: »

Tbh lads being able to goto a shop without wearing a mask or being able to go to a football match with more than 200 people is enough of a return to normal for me

Masks don’t bother me at all. It’s the fact that I can’t go to a live concert/festival is the awful pain....and of course my business relies on crowds to flourish!

Deeper Blue

If a vaccine reduces severe symptoms and therefore hospitalizations and deaths I see no reason why we can't return to normal.

Hmmzis

ACitizenErased wrote: »

Tbh lads being able to goto a shop without wearing a mask or being able to go to a football match with more than 200 people is enough of a return to normal for me

For me it's even more basic than that. Being able to actually plan something for the future. Being able to hug my grandparents and parents would be a great thing. Having kids be be kids again. Having some stability in the economy would be nice as well.

If any of the vaccines or treatments can get this thing down to HKU-1 or OC43 levels, it would be a resounding victory in my book.

ACitizenErased

Luke O'Neill is on front page of Sunday Independent tomorrow saying 'start counting the days'.

greenfield21

So what about these Chinese vaccines, do any of them work etc. Also will they try and sell them to the west. How would they even apply for FDA approval considering the us would probably never believe their results. I have no idea what's going on over there.

ACitizenErased

Good article by Politico on the EU's instruction to the EU nations to prepare for distribution.
In good news, all EU countries will receive the vaccine at the same time.

Kyriakides wouldn't speculate on when these vaccines will be ready, but when they are, the Commission will distribute the vaccines according to population size to all EU countries at the same time.

https://www.politico.eu/article/coronavirus-vaccines-european-commission-tells-countries-to-get-ready/

VG31

I've seen suggestions that the first vaccine will only prevent or greatly reduce the chance of severe symptoms rather than actually give full immunity.

While this doesn't seem ideal, I would have thought it should not be too much of an issue? The main problem with the spread of the virus has been while 95% of people will be fine, you could give it to someone vulnerable. Surely if all the vulnerable people are vaccinated it should allow an end to social distancing, mask wearing etc?

Dickie10

wow im not hearing this anywhere else much, rte like to pedal the statement that this will go on for another 2 years

Away With The Fairies

Has there been other vaccines like this? Where it doesn't give immunity but lessen symptoms?

johnire

What happens the people who for whatever reason don't take a vaccine? Will life continue as it is now for their will they get back to normal on the shirttails of those who do take the vaccine? Also I wonder how they will fare out as regards international travel and travel insurance? I can't imagine any country is going to welcome someone who hasn't had the vaccine if there's one available.

stephenjmcd

Away With The Fairies wrote: »

Has there been other vaccines like this? Where it doesn't give immunity but lessen symptoms?

Yeah, the obvious one being the flu vaccine

Away With The Fairies

stephenjmcd wrote: »

Yeah, the obvious one being the flu vaccine

I thought the flu vaccine depends on the particular flu strain that is going around? It gives immunity to the particular flu strain, but if it's a different flu strain that goes around, that's where the vaccine doesn't work?

Dressoutlet

Away With The Fairies wrote: »

Has there been other vaccines like this? Where it doesn't give immunity but lessen symptoms?

Chicken pox vaccine I think, you get a very mild version of CP if you go on go contract it, although it does give you immunity after contracting the disease but in theory it would be similar.

Dressoutlet

johnire wrote: »

What happens the people who for whatever reason don't take a vaccine? Will life continue as it is now for their will they get back to normal on the shirttails of those who do take the vaccine? Also I wonder how they will fare out as regards international travel and travel insurance? I can't imagine any country is going to welcome someone who hasn't had the vaccine if there's one available.

If they don't get a vaccine they can still get Covid. The people who take a vaccine will be protected from getting sick, but will still be infectious and passing it onto the ones without a vaccine.
It's bad news for people who cannot take the vaccine for whatever reason, but the anti vaxxers will also not benefit from the herd immunity, and will catch covid and either be fine, be dead or be somewhere in the middle.

JP Liz V1

https://twitter.com/MailOnline/status/1317638421716885505

Away With The Fairies

JP Liz V1 wrote: »

https://twitter.com/MailOnline/status/1317638421716885505

Can they help us out?

Wolf359f

JP Liz V1 wrote: »

https://twitter.com/MailOnline/status/1317638421716885505

I won't dismiss a Chinese or Russian vaccine, despite posters on other threads saying there's no Covid vaccine etc...

Obviously the EU can't approve them as they haven't started trials in the EU, but it lessens the demand for EU approved vaccines outside of Europe.