Will you be taking a booster?

The claim was something like $120bn. How do you get at that number from your link?

Sinovac/pharm is whole deactivated virus but has a much lower efficacy than the others. Novavax is again aiming at the spike specifically. The advantage with mRNA (and to a lesser extent adenovector) is that if a stable part of the virus is found, those proteins can be specifically targeted without much retooling. It's much more likely that we'll see traditional vaccines move to mRNA (especially now that the manufacturing capability is there) than vice vera.

Unless of course the "bomb" goes off.

From an investing perspective, the money will follow the treatments as it always does, vaccines tend not to generate the big bucks.

34 weeks pregnant and don't know what to do about the booster.

The issue isn't booster itself but fact I only received my 2nd dose in Sept.

I don't want to be the pregnant guinea pig at this late stage in my pregnancy.

Two weeks ago rule was not to take it unless 6mths gap, then 5 mths now suddenly 3 but absolutely no studies on outcome for people who get a booster after only 3mths, especially pregnant women.

Gp pressuring me to take it, but in same breath I'm not allowed take a cough bottle to help with really bad chest infection as not safe.

Ffs whole thing is a mess.

It's been ok, other vaccines have been cancelled due to similar efficacy (and I have family members who've taken it and had no issues), it's certainly not a panacea for vaccine development, even Novavax, while using older tech for the protein, is using novel technology for stimulating the immune system (maybe that combined with a deactivated virus would work?) the mRNA vaccines efficacy is so high in comparison that it's hard for the others to compete (unless they find a way to stimulate a longer term response, which I don't believe the vaccines have much control over). Its also a case of following the money, most of those not in the mRNA space are moving into it, Pfizer has it's own giant database of results and dosing effects and booster effects from Israel to pore over, Janssen appear to be happy with the adenovector platform but we'll see how long that lasts for.

However, I'd also predict that post pandemic, vaccines will drop down the list (they're too cost efficient and morally they tend to let them get produced generically) and treatment and condition management will become their bread and butter again.

I also did a check, but China are also moving into the mRNA space with a booster in trials (their "efficient" rollout gets around the vaccine hesitancy issues other countries have).

Also, incidentally, Novavax have traditionally been big on flu vaccines and have a combined flu/COVID vaccine in development that could become the annual booster (Moderna are also looking at this and have had good results recently after earlier disappointing results), a seasonal COVID/Flu vaccine (if Summer numbers dip) could be an acceptable level of shots for people to get (nasal vaccines still seem to be a while away, even if Putin got one recently):

Study confirms co-efficacy of Novavax Covid vaccine with flu vaccines – (in-24.com)

Yes Luke the God was saying they are all great vaccines and take any one. Turns out they are all a bit meh.Some decidedly more meh then others. They dont prevent transmission. With latest figures it looks like the most vaccinated countries have the highest transmission rates. Is that behaviour among vaccinated or something else? They do seem to reduce mortality. But cases no. Lets hope the next more mutant variants dont arise from the spread in the now vaxxed populace spreading the majority of it and are more lethal to all.

It has hit me big time... woke up 5 am. in pain today. Still aching, the under arm is the worst. Temp about 37.4 now, headache and I feel like my clothes are hurting me. In other words, not feeling very festive. Could hardly eat and was ready for bed at 7 pm. Hopefully tomorrow is better.

Edit: 37.7 now...

anyone heard how the HSE is meant to handle 3rd dose done in another EU country (in the context of the 9 months validity), when the individual's initial certificate is from Ireland ?

(doesn't seem to be a connection there yet, no mention of 3rd dose here - gov.ie - EU Digital COVID Certificate (www.gov.ie))

yes. Feel free to bring it up in the CT thread about vaccine safety, not this one. Thanks.

Is it the same for people that were vaccinated and then caught Covid say 6-9 months later?

Why? Risk of myocarditis is minute, and much worse if unvaccinated.

Yes quite remote as what can he seen by the Israeli data.

However I don't think that's of benefit to the 26 year old n new Zealand family who died.

What under 40s really would like to see is what is the actual risk here and why take it.

Anytime I look for some data on who under 40, has got serious I'll from Covid there doesn't seem to be anything bar news articles on someone who was asthmatic or overweight. Coupled to omicron on the scene now and what seems less severe.

So many people 40 and under are testing positive last few days and describing a head cold , I think this is the end of this pandemic as once they will have the attitude it was nothing and won't bother with boosters or distancing again.

As I said I regretted getting it , it's almost hyped up to a lottery and u need to be in it or u're missing out , someone here posted to sit back and reflect over Xmas and I wished I listened to them.

If there is some actual data for under 40s with healthy BMI , I'd change my opinion - data from omicron just further fuels opinon though that booster is overkill.

HSE are lashing out moderna as they ordered 2 million of them and need to get rid by mid Jan before they expire.