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Vaccine Megathread No 2 - Read OP before posting

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Comments

  • Registered Users, Registered Users 2 Posts: 2,086 ✭✭✭theguzman


    RobertKK wrote: »
    I am happy we did.

    So am I happy from a Green Jersey perspective but if I was an Indian or Brazilian I'd be fairly pissed reading the news that the likes of Ireland or Denmark are getting to skip the queue by opening the chequebook when both countries have seen the same amount of deaths since the very beginning as the likes of Brazil or India is experiencing Daily!

    We are lucky we are living in a country with such a economically illiterate Govt and robust economy (tax haven) to support the sort of absolutely crazy measures we have seen here since the start compared to other countries where Covid has caused immense serious hardship wheras for Ireland it has given alot of people a huge bonus in terms of free printed money for not working, public and civil servants of full pay at home for a year and a hald. Alot of whome haven't done a tap since Covid and everyone are hiding behind covid because the pandemic suits them better to do nothing at work.

    I think there should be a system of subs where eg. if Romania didn't use its allocation then they would go to countries struggling to vaccinate like African nations and South America. Australia has no-one vaccinated hardly and is now reaping the rewards of their crazy zero-covid approach and the variants rips through them and they thought to pull up the drawbridge forever would work lol.


  • Registered Users, Registered Users 2 Posts: 3,899 ✭✭✭Apogee


    Are we gazumping Denmark here (didn't they announce the same thing, 1 million vaccines from Romania a few days ago) or is this another 1 million that they aren't using.

    Apparently, these are different vaccines
    Indo wrote:
    IRELAND is on the brink of buying one million Covid-19 vaccines from the Romanian government, Independent.ie can exclusively reveal.
    The move will be a massive boost for the vaccination programme amid dire warnings from health chiefs that a fourth wave of Covid-19 is now inevitable.
    In recent days, Romania has halted the importation of vaccines due to a slow uptake among its citizens. Their government already started sending more than one million unwanted doses to Denmark earlier this week.
    https://www.independent.ie/world-news/coronavirus/ireland-to-buy-one-million-unwanted-vaccines-from-romania-40606757.html


  • Registered Users, Registered Users 2 Posts: 3,772 ✭✭✭celt262


    theguzman wrote: »
    So am I happy from a Green Jersey perspective but if I was an Indian or Brazilian I'd be fairly pissed reading the news that the likes of Ireland or Denmark are getting to skip the queue by opening the chequebook when both countries have seen the same amount of deaths since the very beginning as the likes of Brazil or India is experiencing Daily!

    We are lucky we are living in a country with such a economically illiterate Govt and robust economy (tax haven) to support the sort of absolutely crazy measures we have seen here since the start compared to other countries where Covid has caused immense serious hardship wheras for Ireland it has given alot of people a huge bonus in terms of free printed money for not working, public and civil servants of full pay at home for a year and a hald. Alot of whome haven't done a tap since Covid and everyone are hiding behind covid because the pandemic suits them better to do nothing at work.

    I think there should be a system of subs where eg. if Romania didn't use its allocation then they would go to countries struggling to vaccinate like African nations and South America. Australia has no-one vaccinated hardly and is now reaping the rewards of their crazy zero-covid approach and the variants rips through them and they thought to pull up the drawbridge forever would work lol.

    If we didn't but them there would be a mob asking questions and slating the government for not buying them.


  • Registered Users, Registered Users 2 Posts: 355 ✭✭Pat_bottom


    Strazdas wrote: »
    Within days apparently, providing the whole thing goes through okay.

    This feels like your football club making a deadline day signing..... Hope psg don't come in with a late bid.


  • Registered Users, Registered Users 2 Posts: 6,564 ✭✭✭Charles Babbage


    Cork2021 wrote: »
    What in the name of god are the examiner at. An anti vaxxers wet dream headline! And just as it’s opening up to that age group as well

    https://twitter.com/irishexaminer/status/1411025266349019138?s=21


    Clear example of a suspect headline. Having a clot does not necessarily kill you and since the association between clots and AZ is now known and so it is much less likely to kill than in the early days. There was a Professor on the radio during the week describing how they now have a specific test for this type of clot which people can get quickly enough to stop any damage.

    Having Covid can give you other problems other than death of course.


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  • Registered Users, Registered Users 2 Posts: 2,086 ✭✭✭theguzman


    celt262 wrote: »
    If we didn't but them there would be a mob asking questions and slating the government for not buying them.

    I agree totally and buying them is the right thing to do from our point of view, but in the bigger global picture it is actually wrong since we are over the far effects of the pandemic. These vaccines will ensure a bunch of twenty-somethings can go out on the sauce here where they would save alot more lives abroad where they are needed far more.


  • Registered Users, Registered Users 2 Posts: 33,775 ✭✭✭✭RobertKK


    theguzman wrote: »
    So am I happy from a Green Jersey perspective but if I was an Indian or Brazilian I'd be fairly pissed reading the news that the likes of Ireland or Denmark are getting to skip the queue by opening the chequebook when both countries have seen the same amount of deaths since the very beginning as the likes of Brazil or India is experiencing Daily!

    We are lucky we are living in a country with such a economically illiterate Govt and robust economy (tax haven) to support the sort of absolutely crazy measures we have seen here since the start compared to other countries where Covid has caused immense serious hardship wheras for Ireland it has given alot of people a huge bonus in terms of free printed money for not working, public and civil servants of full pay at home for a year and a hald. Alot of whome haven't done a tap since Covid and everyone are hiding behind covid because the pandemic suits them better to do nothing at work.

    I think there should be a system of subs where eg. if Romania didn't use its allocation then they would go to countries struggling to vaccinate like African nations and South America. Australia has no-one vaccinated hardly and is now reaping the rewards of their crazy zero-covid approach and the variants rips through them and they thought to pull up the drawbridge forever would work lol.

    India was exporting vaccines to places like the UK before they stopped exporting.
    Brazil went for Chinese vaccines before getting more like Pfizer as people don't trust the Chinese vaccines.
    These governments could have done better.


  • Posts: 1,662 ✭✭✭ [Deleted User]


    “The case-fatality rate for Delta (0.3%) at this time appears to be lower than that for Alpha (2%)". Per Cillian De Gascun


    Vaccine effectiveness or weaker strain or both?


  • Moderators, Regional Abroad Moderators Posts: 2,474 Mod ✭✭✭✭Nigel Fairservice


    It prompted me to take a look at Europe as a whole.
    I've removed a number of countries for clarity, but you can see clear geographical bands developing based around uptake/supply.

    Anyone got any idea on the history of this? Did a number of these countries have poor prior experience with vaccination programs?

    Delta could rip through many of them very soon

    The bottom half of the table is made up of ex Soviet states. There is still a lot of mistrust of the state in some of these countries which may explain some of the hesitancy.


  • Registered Users, Registered Users 2 Posts: 11,776 ✭✭✭✭ACitizenErased


    Woody79 wrote: »
    “The case-fatality rate for Delta (0.3%) at this time appears to be lower than that for Alpha (2%)". Per Cillian De Gascun


    Vaccine effectiveness or weaker strain or both?
    Could be both. Hard to tell I guess.


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  • Posts: 10,049 ✭✭✭✭ [Deleted User]


    “The case-fatality rate for Delta (0.3%) at this time appears to be lower than that for Alpha (2%)". Per Cillian De Gascun


    Vaccine effectiveness or weaker strain or both?

    Vaccine effectiveness and testing and age.


  • Registered Users, Registered Users 2 Posts: 1,628 ✭✭✭MerlinSouthDub


    Woody79 wrote: »
    “The case-fatality rate for Delta (0.3%) at this time appears to be lower than that for Alpha (2%)". Per Cillian De Gascun


    Vaccine effectiveness or weaker strain or both?

    Much lower average age of those infected (which is a result of the vaccine)


  • Registered Users, Registered Users 2 Posts: 2,086 ✭✭✭theguzman


    Woody79 wrote: »
    “The case-fatality rate for Delta (0.3%) at this time appears to be lower than that for Alpha (2%)". Per Cillian De Gascun


    Vaccine effectiveness or weaker strain or both?

    Vaccine effectiveness in older and at risk groups who have gotten the vaccines now since March-April, the median age of infections is 25 now so it is primarily spreading and infecting people who are younger, stronger and far better able to fight the virus. Ireland is very close to pushing this into the background entirely and the response of the youth to get vaccinated is heartening and they are by and large not anti-vaxx, it is middle aged grumpy karens and mainly English 5G nutcases with a phd in the facebook school of lies and misinformation that are refusing the vaccine.


  • Registered Users, Registered Users 2 Posts: 9,249 ✭✭✭duffman13


    Did you's get any sort of heads up that this was coming ??

    I'm assuming they've also not confirmed expected deliveries in that case yet

    12 hours later replying, crazy day! No heads up, expecting an update operationally from the union/HSE today at some point but it was in the news 3 hours before we got official confirmation.

    A day back and forth working on supplies has been fun. But excited to get going next week

    Expected deliveries is 50 per pharmacy per week for the next few weeks. 400 on most waiting lists at this but it's still an extra 40,000 vaccines administered per week


  • Registered Users, Registered Users 2 Posts: 15,467 ✭✭✭✭stephenjmcd


    duffman13 wrote: »
    12 hours later replying, crazy day! No heads up, expecting an update operationally from the union/HSE today at some point but it was in the news 3 hours before we got official confirmation.

    A day back and forth working on supplies has been fun. But excited to get going next week

    Expected deliveries is 50 per pharmacy per week for the next few weeks. 400 on most waiting lists at this but it's still an extra 40,000 vaccines administered per week

    Yeah better than nothing for sure, sounds like an absolutely mental day.

    I'd say people would be better off applying on the portal too


  • Registered Users, Registered Users 2 Posts: 101 ✭✭Baxtardo


    J&J pharmacy appointment confirmed for Monday 1pm. 31yo. Rang earlier in the week as soon as NIAC guidance was issued, so there is hope for things to move quickly!


  • Registered Users, Registered Users 2 Posts: 9,249 ✭✭✭duffman13


    Yeah better than nothing for sure, sounds like an absolutely mental day.

    I'd say people would be better off applying on the portal too

    I'd be doing that if I was in the 30-34 when that opens.

    Biggest issue is I've seen the same names in multiple stores in the booking system and id imagine these people registered in multiple chains/pharmacies so the no show rate might be worrying. Still given the interest, I can't see a wasted vaccine in pharmacy over the next 3 weeks at least


  • Registered Users, Registered Users 2 Posts: 27 TheGoatOne


    Is there anyone with a Boots appointment that hasn’t been cancelled? Mine for next Friday in Cork is still active so hoping I’ll be sorted then.


  • Registered Users, Registered Users 2 Posts: 532 ✭✭✭xredmanlfcx


    Mr.S wrote: »
    People need to to understand that just because they can now administer from Monday, it’s going to take weeks and weeks, it won’t be over any time soon.

    Patience and you’ll get it over the next few weeks / 2 months.

    2 months :D

    That's what makes it ludicrous for Stephen Donnelly to just randomly announce this morning that about a million people can ring or turn up at pharmacies/chemists today to register for a vaccine.


  • Posts: 1,662 ✭✭✭ [Deleted User]


    Vaccine effectiveness and testing and age.

    Why then is a person who is double dosed with a vaccine (AZ or MRNA) more likely to get infected with Delta (79% protection) than Alpha (89% protection), but less likely to be hospitalised with Delta (96% protection) than Alpha (93% protection)?

    Table 4. Vaccine effectiveness against symptomatic disease for Alpha and Delta variants


    Vaccine Status Vaccine Effectiveness


    Dose 1 Alpha 49 (46 to 52) Delta 35 (32 to 38)
    Dose 2 Alpha 89 (87 to 90) Delta 79 (78 to 80

    Table 5. Vaccine effectiveness against hospitalisation for Alpha and Delta variants

    Vaccine Status Vaccine Effectiveness

    Dose 1 Alpha 78 (64 to 87) Delta 80 (69 to 88)
    Dose 2 Alpha 93 (80 to 97)Delta 96 (91 to 98)






    Virus more infectious but less deadly.


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  • Registered Users, Registered Users 2 Posts: 6,541 ✭✭✭Wolf359f


    Woody79 wrote: »
    Why then is a person who is double dosed with a vaccine (AZ or MRNA) more likely to get infected with Delta (79% protection) than Alpha (89% protection), but less likely to be hospitalised with Delta (96% protection) than Alpha (93% protection)?

    Table 4. Vaccine effectiveness against symptomatic disease for Alpha and Delta variants


    Vaccine Status Vaccine Effectiveness


    Dose 1 Alpha 49 (46 to 52) Delta 35 (32 to 38)
    Dose 2 Alpha 89 (87 to 90) Delta 79 (78 to 80

    Table 5. Vaccine effectiveness against hospitalisation for Alpha and Delta variants

    Vaccine Status Vaccine Effectiveness

    Dose 1 Alpha 78 (64 to 87) Delta 80 (69 to 88)
    Dose 2 Alpha 93 (80 to 97)Delta 96 (91 to 98)






    Virus more infectious but less deadly.
    As we know covid spreads from the most socially active age groups (younger group) and finds it's way up to the older and more vulnerable. Most heat maps show this.

    The data around Alpha was taken during the Xmas wave when the majority of vaccines were given to the old and vulnerable so the vaccine efficiency was taken from this.
    This new Delta wave is currently circulating in the young age groups, so the efficacy being recorded is based on young and healthy vaccinated people.
    It's comparing apples to oranges.


  • Posts: 1,662 ✭✭✭ [Deleted User]


    Wolf359f wrote: »
    As we know covid spreads from the most socially active age groups (younger group) and finds it's way up to the older and more vulnerable. Most heat maps show this.

    The data around Alpha was taken during the Xmas wave when the majority of vaccines were given to the old and vulnerable so the vaccine efficiency was taken from this.
    This new Delta wave is currently circulating in the young age groups, so the efficacy being recorded is based on young and healthy vaccinated people.
    It's comparing apples to oranges.

    Garbage above.

    Your just talking.


  • Registered Users, Registered Users 2 Posts: 6,541 ✭✭✭Wolf359f


    Woody79 wrote: »
    Garbage above.

    Your just talking.

    So you don't think younger people have a higher immune response to a vaccine vs an old and vulnerable person?

    We have been told so many times not to compare vaccine trials from different manufacturers that are run in different countries, at different times on different demographics.

    But comparing the efficacy of a vaccine in an older demographic can be directly compared to the same vaccine in a younger group?


  • Registered Users, Registered Users 2 Posts: 1,570 ✭✭✭Tyrone212


    If you were under 35 and had a choice between J&J or Pfizer in the same week which would you pick?


  • Registered Users, Registered Users 2 Posts: 1,100 ✭✭✭BringBackMick


    Tyrone212 wrote: »
    If you were under 35 and had a choice between J&J or Pfizer in the same week which would you pick?

    J&J now, then likely get Mrna booster in October


  • Posts: 10,049 ✭✭✭✭ [Deleted User]


    Why then is a person who is double dosed with a vaccine (AZ or MRNA) more likely to get infected with Delta (79% protection) than Alpha (89% protection), but less likely to be hospitalised with Delta (96% protection) than Alpha (93% protection)?

    Table 4. Vaccine effectiveness against symptomatic disease for Alpha and Delta variants


    Vaccine Status Vaccine Effectiveness


    Dose 1 Alpha 49 (46 to 52) Delta 35 (32 to 38)
    Dose 2 Alpha 89 (87 to 90) Delta 79 (78 to 80

    Table 5. Vaccine effectiveness against hospitalisation for Alpha and Delta variants

    Vaccine Status Vaccine Effectiveness

    Dose 1 Alpha 78 (64 to 87) Delta 80 (69 to 88)
    Dose 2 Alpha 93 (80 to 97)Delta 96 (91 to 98)






    Virus more infectious but less deadly.

    You need to read up on confidence intervals


  • Registered Users, Registered Users 2 Posts: 583 ✭✭✭crooked cockney villain


    Has the government come out and said that there will be a system to ensure people who have recently had Covid will not have a J&J vaccine wasted on them when a single Pfizer/ AZ will do?


  • Registered Users, Registered Users 2 Posts: 32,132 ✭✭✭✭is_that_so


    But surely it should be proportionate to capacity. With 5k a day capacity Citywest should obviously be doing a larger population than a smaller regional centre, but it seems disproportionate - it's covering several of the most populous suburbs in the country. I trusted that capacity was fairly evenly spread across regions, I'm doubting that now but would have thought there's some actual data on it.

    Capacity is not really that well spread in the higher population regions around Dublin. In both Meath and Louth they can deal with better distributed populations but the much larger southern population bulge in both is sending people further afield. One would imagine Kildare is the same.


  • Posts: 939 ✭✭✭ [Deleted User]


    Tyrone212 wrote: »
    If you were under 35 and had a choice between J&J or Pfizer in the same week which would you pick?

    Pfizer

    Higher efficacy

    Better evidence of prevention of spread

    Less likelihood of booster requirement

    Great safety profile


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  • Registered Users, Registered Users 2 Posts: 32,132 ✭✭✭✭is_that_so


    Pfizer

    Higher efficacy

    Better evidence of prevention of spread

    Less likelihood of booster requirement

    Great safety profile
    Versus one and done of J&J, which is effective against variants.


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