Vaccine Megathread - See OP for threadbans

revelman · 26-04-2021 10:24AM

Lumen wrote: »

I'm not even sure whether that's good or bad news. Both?

All medicines have potential side effects. I think all the EMA approved vaccines should be available to everyone, no matter what their age as long as there is consent. But that is just my personal opinion.

Sanjuro · 26-04-2021 10:29AM

Was talking to a mate of mine last night who lives in Belfast. Just a year older than me (40). He got his first shot last week. A mixture of emotions. Firstly, incredible frustration that we're not at the same pace. Even though the differences in how to approach vaccinating the population is understood and I do prefer our approach. Secondly, very encouraging hearing him be all upbeat about things. I'm looking forward to when we're at that stage.

Lumen · 26-04-2021 10:30AM

revelman wrote: »

All medicines have potential side effects. I think all the EMA approved vaccines should be available to everyone, no matter what their age as long as there is consent. But that is just my personal opinion.

Vaccines are not normal medicines, because they are (a) prophylactic, and (b) partly intended to protect people other than the the recipient.

This is why vaccine approval is so much tougher than for normal medicine. (I appreciate that the EMA has approved J&J, it's a general point).

"First, do not harm" and all that.

JPA · 26-04-2021 10:34AM

VinLieger wrote: »

So I heard something on the radio a few a few weeks back that confused me when AZ was being stopped for the under 65s, someone was reporting any health care workers who had 1 shot of AZ would instead be getting a 2nd shot of Pfizer or Moderna. How is this possible since they are based on 2 different vaccine technologies?

If you did hear that it is totally wrong.
Anyone who got 1st dose of AZ will get a 2nd dose as well.

Red Silurian · 26-04-2021 10:35AM

Lumen wrote: »

I don't think it's completely unreasonable to provide young people (who themselves are at almost zero risk from COVID) with the vaccines having the least bad side effects, i.e. the mRNA vaccines, as long as that can be accommodated without delaying the rollout.

If we end up with a couple of twenty-somethings dead from clotting events because it was too much effort to manage the streams of vaccines a bit better, then that would be...I'm looking for the right word...tragic? regrettable? incompetent? I don't know.

Vaccinate the young reduces transmission so makes medical sense... Of course one of the reasons transmission is high in the young is because many of them are flouting the restrictions so it would look like it is 'promoting bad behavior'

Medically it would be a good idea but politically it would be suicide

TheDoctor · 26-04-2021 10:35AM

Has the dose gap for AZ been pushed out to 16 weeks or is it still 12?

Sparko · 26-04-2021 10:40AM

TheDoctor wrote: »

Has the dose gap for AZ been pushed out to 16 weeks or is it still 12?

My understanding is if you are under 60 with no underlying conditions and have already gotten a dose, then it has been extended to 16 weeks. Over 60s and under 60s with high risk conditions are staying at 12 weeks.

My mother is in her 60s and got her first dose of AZ over the weekend, she was told it'd be 12 weeks.

26-04-2021 10:43AM

revelman wrote: »

https://www.timesofisrael.com/israel-said-probing-link-between-pfizer-shot-and-heart-problem-in-men-under-30/

Expected rates of myocarditis are 10-20 per 100k per year. So if you take the lower end of that range Israel would expect about 250 cases in 3 months. Younger males also have a higher rate of myocarditis than the general population. So, 62 cases in Israel with a higher prevalence in younger males is not something to be overly concerned about

Charles Babbage · 26-04-2021 10:45AM

Sparko wrote: »

My understanding is if you are under 60 with no underlying conditions and have already gotten a dose, then it has been extended to 16 weeks. Over 60s and under 60s with high risk conditions are staying at 12 weeks.

My mother is in her 60s and got her first dose of AZ over the weekend, she was told it'd be 12 weeks.

So a 60 year old vaccinated towards the end of May, and some will be, will not get a second jab until the end of August and will be one of the last people to be fully vaccinated? What are they going to do with the AZ in the meantime?

FlubberJones · 26-04-2021 10:56AM

I have an appointment to get a vaccine this coming bank holiday weekend. I would have to travel over on the Ferry to Holyhead on Friday night, get out and get a PCR test on the Saturday, get the vaccine on the Sunday then travel back on the Monday.
This would be heavily reliant on the PCR negative test results being available to me by the bank holiday Monday morning.

I'm trying to balance up both the cost and the benefit here and obviously when I will get vaccinated in Ireland if I didn't do this.

Russman · 26-04-2021 10:58AM

Charles Babbage wrote: »

So a 60 year old vaccinatined towards the end of May, and some will be, will not get a second jab until the end of August and will be one of the last people to be fully vaccinated? What are they going to do with the AZ in the meantime?

I'd imagine hold what we need for second doses in storage, and come August/September when the 60s have their shots, that's us & the EU done with AZ for ever more.

26-04-2021 10:59AM

cool

26-04-2021 11:01AM

I'm not sure what the benefits of this are?

26-04-2021 11:04AM

The clotting incidence rate for J&J is 7 per million in women under 50.

For women in their 30s, it's 11.8 per million.

These are similar rates to AZ (albeit for a more specific cohort), so I can't really understand the logic in restricting one and not the other.

In the US, people have some choice over which vaccine they get, it's not a case of "take J&J or get to the back of the queue."

Lumen · 26-04-2021 11:05AM

Flying Fox wrote: »

The clotting incidence rate for J&J is 7 per million in women under 50.

For women in their 30s, it's 11.8 per million.

These are similar rates to AZ, so I can't really understand the logic in restricting one and not the other.

J&J is single dose, so that adjusts the risk downwards.

1huge1 · 26-04-2021 11:06AM

FrankN1 wrote: »

When are they due to start 20-30s?

Vicxas wrote: »

June(ish) all going well

I'd assume early to mid July for people in their 20s, they want 80% of Adults to have their first dose by the end of June, presumably then the 20% is the 18-30yr old cohort?

This is based on 80% of adults having their first dose by the end of June which is the target.

Russman · 26-04-2021 11:09AM

is_that_so wrote: »

They can but they also know that will delay the vaccination programme and Butler does seem keen to get people vaccinated as fast as we can. I won't be surprised either way but logic suggests they should approve it for all.

I guess it depends on what weight they'd put on the speed of the programme. As you say, could go either way.

stephenjmcd · 26-04-2021 11:10AM

25,832 for Saturday

21070 first dose
4762 second dose

FlubberJones · 26-04-2021 11:10AM

I am also wondering of the benefits, if the vaccine will be sooner rather than later for a over 50s then I would wait for my turn to come around in Ireland.

seamus · 26-04-2021 11:11AM

1huge1 wrote: »

I'd assume early to mid July for people in their 20s, they want 80% of Adults to have their first dose by the end of June, presumably then the 20% is the 18-30yr old cohort?

Yeah, I wouldn't expect under-35s to be jabbed until well into July. I'm (barely) under 40 and I'm hoping but not expecting a jab before the end of June.

26-04-2021 11:11AM

Lumen wrote: »

J&J is single dose, so that adjusts the risk downwards.

We don't have enough data yet on the second dose risks for AZ, so it's not really possible to compare at this stage.

Russman · 26-04-2021 11:12AM

Flying Fox wrote: »

The clotting incidence rate for J&J is 7 per million in women under 50.

For women in their 30s, it's 11.8 per million.

These are similar rates to AZ (albeit for a more specific cohort), so I can't really understand the logic in restricting one and not the other.

In the US, people have some choice over which vaccine they get, it's not a case of "take J&J or get to the back of the queue."

If those rates are correct & are similar to AZ (not doubting you), then its hard to imagine there not being some restriction. Would AZ have any legal recourse if the rates were the same and no restriction placed on J&J ?

Your last sentence could be quite important for context also, a degree of vaccine choice is a huge mitigating factor IMO.

seamus · 26-04-2021 11:13AM

stephenjmcd wrote: »

25,832 for Saturday

21070 first dose
4762 second dose

If we reached 1m first doses yesterday, then that's at least 13,000 first doses done yesterday.

Eyeballing it, they're the biggest weekend numbers by a very long way. I haven't verified that though.

Strazdas · 26-04-2021 11:13AM

Sanjuro wrote: »

Was talking to a mate of mine last night who lives in Belfast. Just a year older than me (40). He got his first shot last week. A mixture of emotions. Firstly, incredible frustration that we're not at the same pace. Even though the differences in how to approach vaccinating the population is understood and I do prefer our approach. Secondly, very encouraging hearing him be all upbeat about things. I'm looking forward to when we're at that stage.

But we're gaining pace on them rapidly. In mid March, we were nearly three months behind them. At the moment it's eight weeks.....soon it will be four weeks etc.

26-04-2021 11:18AM

Well, I don't see that it is any individual benefit to you to have the vaccine even a.couple of months before you would here?
Life won't change until the majority of the country is vaccinated.
There's nothing wrong with getting it early, if it suited you to do it.

Pete_Cavan · 26-04-2021 11:19AM

seamus wrote: »

If we reached 1m first doses yesterday, then that's at least 13,000 first doses done yesterday.

Eyeballing it, they're the biggest weekend numbers by a very long way. I haven't verified that though.

Yes I was expecting the 1,000,000th person dose to happen today, getting it done at the weekend is impressive. Should sail past 1.5m doses before next weekend. How would 1.5m doses administered at end of April compare with earlier targets?

JPup · 26-04-2021 11:22AM

What vaccine would you get in the UK? How would you get the second dose? Same trip again?

It's a lot of expense and effort. If you are over 50 chances are you will be vaccinated here in the next 4-6 weeks. Unlikely to be AZ also, so your second dose would be another 4-6 weeks after that.

Lucas Hood · 26-04-2021 11:24AM

https://twitter.com/IrelandVaccine/status/1386621657272496128?s=19

Good week.

Atlantic Dawn · 26-04-2021 11:25AM

I'd wait, the risk of exposure to the virus while travelling nullifies the benefits of getting it early, far better to wait. The expense is another reason not to.

odyssey06 · 26-04-2021 11:25AM

A family member is in Group 7 of high risk, under 60.
Their GP surgery is not participating in the rollout because "AZ is not available".

Family member now seems to be in limbo as there doesn't seem to be any Plan B?
GP hasn't said anything along the lines of "We will register you for an MVC" and self registration on HSE is age based only.

Anyone else in same boat?

Vaccine Megathread - See OP for threadbans

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