Vaccine Megathread - See OP for threadbans

Russman · 22-04-2021 09:32AM

Lumen wrote: »

Difficult to compare. If I was given the choice I'd rather have mRNA, in the same way that I'd rather own a Ferrari than a Lamborghini.

https://www.statnews.com/2021/02/02/comparing-the-covid-19-vaccines-developed-by-pfizer-moderna-and-johnson-johnson/

From a practical perspective I'd rather have J&J because I'd be considered fully vaccinated sooner.

Thanks Lumen, that's a really interesting article

Cazale · 22-04-2021 09:36AM

The missus is from the North and got the Astrazenica vaccine up there the day before they restricted the age groups. She's now very reticent to get the second jab. I can get her the Pfizer vaccine now through work. Is there any guidelines or data on getting Astrazenica and then Pfizer?

Turtwig · 22-04-2021 09:41AM

Russman wrote: »

So, for the layman, how does J&J compare to AZ in terms of effectiveness ? Leaving aside the obvious benefits of being one dose Vs two doses.

I'd take any of them tomorrow if offered, and I know we won't have a choice, just curious as to which might be viewed as "better".

They do exactly what they say on the tin.

Hmmzis · 22-04-2021 09:41AM

Russman wrote: »

So, for the layman, how does J&J compare to AZ in terms of effectiveness ? Leaving aside the obvious benefits of being one dose Vs two doses.

I'd take any of them tomorrow if offered, and I know we won't have a choice, just curious as to which might be viewed as "better".

When it comes to comparing the trials it's effectively impossible to compare as the protocols, locations, timing are all quite different. Even the primary endpoint definitions are quite different. The only consistent(-ish) endpoint definition for all is for severe/critical cases. There all of the vaccines seem to be on par with each other.

The real world data from the UK does show that AZ after one dose is slightly more efficacious than Pfizer/BNT after one dose against severe/critical cases.
Since not enough time has passed since the booster shots, we don't have that data yet after boosters have been given.

seamus · 22-04-2021 09:46AM

Cazale wrote: »

The missus is from the North and got the Astrazenica vaccine up there the day before they restricted the age groups. She's now very reticent to get the second jab. I can get her the Pfizer vaccine now through work. Is there any guidelines or data on getting Astrazenica and then Pfizer?

No. Some countries are mixing and matching, but there's no data on it.

The recommendation here would be to get two Pfizer doses, as if she hasn't been vaccinated at all, and not to consider herself fully vaccinated after one Pfizer dose.

There is no danger in doing this, but she can always ask her GP for guidance.

lbj666 · 22-04-2021 09:59AM

Hmmzis wrote: »

This from the paper is for me the most important finding:

Efficacy against Covid-19 involving hospitalization was 93% with regard to onset at least 14 days after administration (2 cases in the vaccine group and 29 in the placebo group) and 100% with regard to onset at least 28 days after administration (no hospitalizations in the vaccine group and 16 in the placebo group).

Exactly , it is was simply 82% efficacious against severe illness the whole time, thats far from a reduction to neglible levels.

stephenjmcd · 22-04-2021 09:59AM

Good to see the portal opening for more tomorrow.

Registered my father on Monday (aged 65) so hopefully should hear something in the next few days

22-04-2021 10:01AM

Hmmzis wrote: »

This from the paper is for me the most important finding:

Excellent news. Anyone told the ISAG?

Sconsey · 22-04-2021 10:02AM

funnydoggy wrote: »

Micheál confirmed it ☺️

https://twitter.com/MichealMartinTD/status/1385111432916832256?s=20

Have they completely thrown out their own plan at this stage? What happened to following the plan they have published which states the high risk come after the over (or even parallel) with the obver 65's. I suppose the tweet says they are asking peopel to register, not that stating when thy will be scheduled. Still though.

is_that_so · 22-04-2021 10:07AM

Sconsey wrote: »

Have they completely thrown out their own plan at this stage? What happened to following the plan they have published which states the high risk come after the over (or even parallel) with the obver 65's. I suppose the tweet says they are asking peopel to register, not that stating when thy will be scheduled. Still though.

Ok, that whole Group 1-7 is not part of the portal in any way. They are still ongoing separately in the original HSE categorisation plan.

harr · 22-04-2021 10:11AM

Sconsey wrote: »

Have they completely thrown out their own plan at this stage? What happened to following the plan they have published which states the high risk come after the over (or even parallel) with the obver 65's. I suppose the tweet says they are asking peopel to register, not that stating when thy will be scheduled. Still though.

Are the high risk not being done by GPs only ? I know a few people high risk and waiting for GP appointments.. the age groups getting done in vaccination centres will tip along and get done quicker.
Still GPs here struggling to finish the over 70s while I know a good few 65-70 who have been done first .

Bubbaclaus · 22-04-2021 10:13AM

Sconsey wrote: »

Have they completely thrown out their own plan at this stage? What happened to following the plan they have published which states the high risk come after the over (or even parallel) with the obver 65's. I suppose the tweet says they are asking peopel to register, not that stating when thy will be scheduled. Still though.

The 60-64 age group are getting a different vaccine to the high risk groups. It wouldn't make any sense to wait for high risk to be done.

sd1999 · 22-04-2021 10:13AM

Sconsey wrote: »

Have they completely thrown out their own plan at this stage? What happened to following the plan they have published which states the high risk come after the over (or even parallel) with the obver 65's. I suppose the tweet says they are asking peopel to register, not that stating when thy will be scheduled. Still though.

Over 60s are getting AZ and cohorts 4 and 7 aren’t. There’s no reason to delay the over 60s because the AZ vaccines can’t be prioritised for anyone else.

horse7 · 22-04-2021 10:14AM

Are hospital consultants going through their patient list and getting urgent people vaccinated?

Van.Bosch · 22-04-2021 10:18AM

The reporting on HSE and the Covid hub seems to be a bit out of line with the cohorts now. Cohort 5 has 4423 first doses done as at Tuesday which I assume is 65-69 but the hub still shows that as being high risk 65-69?

Lucas Hood · 22-04-2021 10:18AM

About 20k done on Tuesday
https://www.hse.ie/eng/services/news/newsfeatures/covid19-updates/vaccination-programme-dashboard-as-of-20-april-2021.pdf

Hmmzis · 22-04-2021 10:19AM

Mum got her first dose today (Moderna). That's now all the vulnerable in my immediate family with at least one dose. The mind is getting more at ease.

ceegee · 22-04-2021 10:23AM

Lucas Hood wrote: »

About 20k done on Tuesday
https://www.hse.ie/eng/services/news/newsfeatures/covid19-updates/vaccination-programme-dashboard-as-of-20-april-2021.pdf

About 5000 AZ. Hopefully that's down to lag rather than an accurate reflection of the MVCs.

Zipppy · 22-04-2021 10:24AM

Sconsey wrote: »

Have they completely thrown out their own plan at this stage? What happened to following the plan they have published which states the high risk come after the over (or even parallel) with the obver 65's. I suppose the tweet says they are asking peopel to register, not that stating when thy will be scheduled. Still though.

Exactly , at this stage they'll be vaccinating the 30s and many high risk will still be waiting...

TheDoctor · 22-04-2021 10:24AM

Lucas Hood wrote: »

About 20k done on Tuesday
https://www.hse.ie/eng/services/news/newsfeatures/covid19-updates/vaccination-programme-dashboard-as-of-20-april-2021.pdf

This feels on the low side? Or is it as expected this week?

landofthetree · 22-04-2021 10:26AM

The auld tart on RTE radio seems to be against vaccine passports.

TomOnBoard · 22-04-2021 10:27AM

Sconsey wrote: »

Have they completely thrown out their own plan at this stage? What happened to following the plan they have published which states the high risk come after the over (or even parallel) with the obver 65's. I suppose the tweet says they are asking peopel to register, not that stating when thy will be scheduled. Still though.

I think its a case of what a famous Prussian General said back in the 19th Century-

" No battle plan survives the first contact with the enemy! " or words to that effect. I'll accept that rationale, so long as it doesn't descend into a keystone cops scenario...

Bubbaclaus · 22-04-2021 10:27AM

TheDoctor wrote: »

This feels on the low side? Or is it as expected this week?

Best Tuesday yet I think.

sd1999 · 22-04-2021 10:28AM

Zipppy wrote: »

Exactly , at this stage they'll be vaccinating the 30s and many high risk will still be waiting...

They won’t because under 60s, high risk or not, will be getting Pfizer or Moderna. Both of those will be prioritised for high risk people before moving on to the general population. Over 60s got lucky with the AZ ruling but they’re the only group that will be getting vaccinated a bit ahead of the high risk groups.

is_that_so · 22-04-2021 10:32AM

horse7 wrote: »

Are hospital consultants going through their patient list and getting urgent people vaccinated?

Anecdotally yes. I know of a few this week. How they are organising it, though, is a complete mystery!

seamus · 22-04-2021 10:34AM

Lucas Hood wrote: »

About 20k done on Tuesday
https://www.hse.ie/eng/services/news/newsfeatures/covid19-updates/vaccination-programme-dashboard-as-of-20-april-2021.pdf

I was going to say I was disappointed by that, but as has been pointed out above, that is actually in line with previous Tuesdays. Not the biggest, but not far off. There may also be a lag in data that will bring it up.

gmisk · 22-04-2021 10:34AM

Just wondering if anyone here in NI had a vaccine?
I am able to book an appointment now (35-39).
I didn't need NHS number, dob and address was sufficient.
I am just wondering do I need proof of address when I attend at the SSE? (Have UK passport etc for photo ID)
I can go home to get a letter or something but would be a serious trek!, Is it something they are checking?

Lucas Hood · 22-04-2021 10:36AM

Bubbaclaus wrote: »

Best Tuesday yet I think.

3rd highest with 20010

6 april (21004) and 30 March (20885) were higher.

Zipppy · 22-04-2021 10:37AM

sd1999 wrote: »

They won’t because under 60s, high risk or not, will be getting Pfizer or Moderna. Both of those will be prioritised for high risk people before moving on to the general population. Over 60s got lucky with the AZ ruling but they’re the only group that will be getting vaccinated a bit ahead of the high risk groups.

So we're saying that current vaccinations are:

Remaining over 70s: Pfizer
65-69s: AZ
High Risk/Very High Risk: Pfizer

SJFly · 22-04-2021 10:40AM

sd1999 wrote: »

They won’t because under 60s, high risk or not, will be getting Pfizer or Moderna. Both of those will be prioritised for high risk people before moving on to the general population. Over 60s got lucky with the AZ ruling but they’re the only group that will be getting vaccinated a bit ahead of the high risk groups.

It will be interesting to see what happens next in the MVCs when over 60s are done, which could be quite soon in some regions. The GP rollout is slow, with deliveries every other week. I think it's unlikely group 7 will be finished before the MVCs could be on to over 50s. I don't particularly have a problem with that, but I imagine it will cause a lot of outrage.

Vaccine Megathread - See OP for threadbans

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