Vaccine Megathread - See OP for threadbans

Doctor Jimbob wrote: »

If this happens as planned I'd imagine AZ will be politely told to take their vaccine elsewhere shortly. I'd have no issue taking AZ (I'd take it tomorrow if offered!) but with Pfizer performing like this, AZ are getting less and less worth the hassle.

Danzy wrote: »

Pfizer still aren't going to be enough to save the summer for the economies of Europe.

Especially if Johnson is delayed as well.

The impact of that will cost much more in lives lost and destroyed.

rm212 wrote: »

More than covers that figure that was floating around regarding some doses of AZ possibly going unused with the new guidelines.

EDIT: In fact, looking at those charts, it gets close to covering the entire Q2 delivery of AZ to the EU!

European Union countries will receive 50 million more Covid-19 vaccines produced by Pfizer and BioNTech in the second quarter, the head of the EU commission said on Wednesday, as deliveries expected at the end of the year are brought forward.

Van.Bosch wrote: »

We should really have a bank Holiday to honour the guys in Biontech who created the vaccine and the gang at Pfizer who produced it in huge numbers.

If/when we get out of this, that vaccine is going to have played a massive roll - and to think a few months ago AZ was considered the game changer

funnydoggy wrote: »

Rumblings about Alzheimer's too in the last week

is_that_so wrote: »

MS too is under research by BionTech.

Romark Announces Initial Results Of Phase 3 Clinical Trial Of NT-300 Tablets For The Treatment Of COVID-19


TAMPA, Fla., April 14, 2021 /PRNewswire/ -- Romark announced today initial results of a Phase 3 clinical trial of its investigational new drug candidate NT-300 (nitazoxanide extended-release tablets, 300 mg) versus placebo as a treatment for mild or moderate COVID-19. Based on the findings, Romark is working with the U.S. Food and Drug Administration (FDA) and plans to seek Emergency Use Authorization (EUA).

In the analysis of the primary endpoint, median time to sustained response (a measure of recovery time) was similar for subjects treated with NT-300 compared with placebo (approximately 13 days). In the pre-defined subgroup of patients with mild disease, median time to sustained response was reduced by 3.1 days with NT-300 (10.3 days, n=116) versus placebo (13.4 days, n=129).

In the analysis of the key secondary endpoint, treatment with NT-300 was associated with an 85% (0.5% of NT-300-treated patients vs. 3.6% of patients treated with placebo) reduction in the progression to severe illness (shortness of breath at rest with SpO2 ≤93% on room air or PaO2/FiO2<300). Only one person treated with NT-300 progressed to severe COVID-19 disease. In the pre-defined subgroup at high risk of severe illness according to CDC criteria, 7/126 (5.6%) of placebo-treated subjects experienced severe illness compared to 1/112 (0.9%) of NT-300-treated subjects.

ACitizenErased wrote: »

That Pfizer news is absolutely huge. That's 250k more fully vaccinated people.

TomOnBoard wrote: »

500,000 with a cohort average of 80+ effectiveness if they adopt a one shot strategy and get everyone covered, with a booster/2nd shot once all have got the 80+% protection.

TomOnBoard wrote: »

500,000 with a cohort average of 80+ effectiveness if they adopt a one shot strategy and get everyone covered, with a booster/2nd shot once all have got the 80+% protection.

bucketybuck wrote: »

It highlights a problem with our governments approach since the very start, they completely ignored the human element in all this.

The young people of this country have been treated disgracefully in this past year, they had everything taken away from them while never being treated as anything more than collateral damage. Their jobs, their education and their chances all taken away and then told to stop whining and "hold firm".

Now they are being told to take a vaccine that possibly could kill them to protect against a virus that doesn't hurt them, all to protect people that did nothing for them. And we wonder why they may have stopped giving a damn?

I'm not young and I'll have my vaccine in the next few weeks, but I can completely see how extremely poor messaging and communication this past year has led to a situation where a lot of people may no longer care how selfish they are or are not.