What exactly is happening with AstraZeneca?

pueblo · 06-04-2021 05:04PM

Carefully worded.

AFP News Agency
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#UPDATE European Medicines Agency (#EMA) head of vaccines Marco Cavaleri said in an interview published on Tuesday that there is a link between the #AstraZeneca coronavirus vaccine and blood clots, but the cause of "this reaction" is still not clear http://u.afp.com/UMpi

mista11 · 06-04-2021 05:29PM

correct horse battery staple wrote: »

I didn’t say anything about their rollout, they are injecting people just as fast as we are, the only difference is they got more of these AZ vaccines faster unlike us where AZ is fraction of total

However it’s starting to look like AZ is nowhere as good as advertised and now news coming out it could be downright dangerous to a healthy/young section of population

Cheering on Tories (for work done by NHS which they are privatising) is the last thing I will do. It’s like cheering on Mayor Quinby after the firefighters put out fire which burned down half of Springfield, with water being used instead of foam for an electric fire.

Its exactly as good as advertised - 100% effective against death against original and UK varient of COVID, you need to stop scaremongering

Lots of young women have alot to consider if they get offered this vaccine, they dont need to read your politically driven drivel clouding their minds

06-04-2021 05:44PM

The Astrazeneca Trials in children and teenagers have now been paused.

Melanchthon · 06-04-2021 05:46PM

Call me Al wrote: »

Is this a quiz?
A quiz that Norwegian medics never took in their training perhaps?
If they are medically qualified enough to realise that the numbers of recently-vaccinated people presenting with ITP are out of kilter then I'm sure they know enough to investigate and account for underlying conditions and medications that may be involved..

It was a bit actually, since you said you were familiar with it I am suprised you didn't mention Heparin when I asked about medication.

The people in other countries and the people running the trials are also medically qualified, the Norwegian results are an outlier at the minute.

Why trust the Norway figures and not the others.

josip · 06-04-2021 05:56PM

Deleted User wrote: »

The Astrazeneca Trials in children and teenagers have now been paused.

That's actually news since the blood clotting is more prevalent in younger women.

Beechwoodspark · 06-04-2021 06:10PM

[Deleted User] wrote: »

The Astrazeneca Trials in children and teenagers have now been paused.

Not good

Why am I getting anxiety about the AZ vaccine

Will we possibly get even worse news later in the year when ppl have been vaccinated and it’s “too late”??...

Call me Al · 06-04-2021 06:28PM

Melanchthon wrote: »

It was a bit actually, since you said you were familiar with it I am suprised you didn't mention Heparin when I asked about medication.

The people in other countries and the people running the trials are also medically qualified, the Norwegian results are an outlier at the minute.

Why trust the Norway figures and not the others.

Do you normally feel the need to give quizzes to people who post on this thread?
Why on earth would you? Do you not believe me or something?
It's a very odd way to respond to what's a fairly innocuous statement about ITP (which also happens to be true).

Edit I would trust the figures as they are specific diagnoses. I can't see them misdiagnosing anything in the current environment.
I'd imagine those cases have been thoroughly analysed by more than just Norwegian authoritiesat this stage.

Pete_Cavan · 06-04-2021 06:36PM

Beechwoodspark wrote: »

Will we possibly get even worse news later in the year when ppl have been vaccinated and it’s “too late”??...

It seems as though if you haven't developed a blood clot in the first couple of weeks, you aren't going to have a problem. I can't see that being an issue.

Strazdas · 06-04-2021 07:29PM

Deleted User wrote: »

The Astrazeneca Trials in children and teenagers have now been paused.

It's been pointed out that to give a vaccine with some question marks to healthy young people at zero risk of dying from Covid would be questionable to say the least, even if the actual risk from the vaccine is very, very low.

06-04-2021 07:30PM

Beechwoodspark wrote: »

Not good

Why am I getting anxiety about the AZ vaccine

Will we possibly get even worse news later in the year when ppl have been vaccinated and it’s “too late”??...

Generally, as I understand it, the issues have presented themselves soon after immunisation, so I don’t think there are on going worries identified long after vaccination

06-04-2021 07:33PM

Pete_Cavan wrote: »

It seems as though if you haven't developed a blood clot in the first couple of weeks, you aren't going to have a problem. I can't see that being an issue.

Is there anyway of mitigating risk of clotting.

McConkey recently mentioned exercise reduces risk of clotting and not being dehydrated.

JTMan · 06-04-2021 07:45PM

Deleted User wrote: »

The Astrazeneca Trials in children and teenagers have now been paused.

Pfizer are doing trials in 12-15 year olds. (With younger kids at a later stage).
Moderna are doing trials in 12-17 year olds. (With younger kids at a later stage).
AZ were doing trials in 6-17 year olds.

All were expected to be approved before schools reopen in September.

I was hoping that in August, that we would vaccinate 12-15 year olds with Pfizer and 6-11 year olds with AZ.

Now with the AZ trial paused it might just be 12-15 year olds that are vaccinated in August.

If the AZ trail does not resume, we could be waiting until Q1 2022 before we vaccinate those 11 and under.

murphaph · 06-04-2021 08:12PM

What has caused the huge drop in vaccinations in the UK over the past few days? Just lack of supply?

https://coronavirus.data.gov.uk/details/vaccinations

astrofool · 06-04-2021 08:15PM

murphaph wrote: »

What has caused the huge drop in vaccinations in the UK over the past few days? Just lack of supply?

https://coronavirus.data.gov.uk/details/vaccinations

Supply and making sure they have enough kept back for second shots.

BorneTobyWilde · 06-04-2021 10:48PM

Astrazeneca should be dumped. Other vaccines available, one death is too many from a dodgy vaccine. Just use the other ones instead.

Lesalare · 06-04-2021 10:50PM

I'm extremely worried about Astrazeneca being my only option. I have severe Raynaud's disease and my Father died at 55 from a stroke.
I am starting to ponder if I should refuse it if it's the only option given to me - which obviously I don't want to have to do.

LLMMLL · 06-04-2021 10:53PM

Lesalare wrote: »

I'm extremely worried about Astrazeneca being my only option. I have severe Raynaud's disease and my Father died at 55 from a stroke.
I am starting to ponder if I should refuse it if it's the only option given to me - which obviously I don't want to have to do.

Why do you think it will put you at risk?

Lesalare · 06-04-2021 10:59PM

LLMMLL wrote: »

Why do you think it will put you at risk?

Because I have Raynaud's disease and my father died from a stroke at 55.

"Can Raynaud's cause blood clots?
We seem to find that patients with autoimmune diseases have a higher frequency of Raynaud's than the general population. Scleroderma has the strongest association. In phospholipid syndrome, a person has certain blood proteins that predispose them to sluggish blood flow or blood clots that may show up as Raynaud's"

So I am somewhat worried, yet it's not on an 'underlying condition' list.

I'm not sure how happy I am to have this AZ jab anymore. I'm actually more worried about being forced to take it than the fact I've hibernated away for the past 12 months and followed social guidelines by the book.

LLMMLL · 06-04-2021 11:00PM

Lesalare wrote: »

Because I have Raynaud's disease and my father died from a stroke at 55.

Is there any indication that People with Raynaud’s are more likely to have an adverse reaction with AstraZeneca?

mista11 · 06-04-2021 11:09PM

BorneTobyWilde wrote: »

Astrazeneca should be dumped. Other vaccines available, one death is too many from a dodgy vaccine. Just use the other ones instead.

How many more people will die waiting for the other vaccines?

Lesalare · 06-04-2021 11:13PM

LLMMLL wrote: »

Is there any indication that People with Raynaud’s are more likely to have an adverse reaction with AstraZeneca?

I'm reading through this: https://link.springer.com/article/10.1007/s11239-019-01805-0#Sec12

I'm still looking into it. I am a tad concerned though. I'll obvs read up throughly on it. Considering Raynaud's is a condition to constriction of blood vessels, of course I am concerned. But I'll research it and get advice and make a call.

Multipass · 06-04-2021 11:15PM

BorneTobyWilde wrote: »

Astrazeneca should be dumped. Other vaccines available, one death is too many from a dodgy vaccine. Just use the other ones instead.

There are deaths from every vaccine in existence, you’d better dump the lot.

LLMMLL · 06-04-2021 11:17PM

Lesalare wrote: »

I'm reading through this: https://link.springer.com/article/10.1007/s11239-019-01805-0#Sec12

I'm still looking into it. I am a tad concerned though. I'll obvs read up throughly on it. Considering Raynaud's is a condition to constriction of blood vessels, of course I am concerned. But I'll look into it.

I honestly think that article is not going to help you. It has zero information on AZ vaccine or any other vaccine. Unless you’re a medical expert with a specialty in RP or vaccines then how will you use that article to assess your risk? How will you know if the issues talked about in that article are been vaguely related to the issues a tiny number of people face after a vaccine?

What would you advise a relative with RP to do?

quokula · 06-04-2021 11:22PM

Strazdas wrote: »

It's been pointed out that to give a vaccine with some question marks to healthy young people at zero risk of dying from Covid would be questionable to say the least, even if the actual risk from the vaccine is very, very low.

Healthy young people aren’t at zero risk of dying from covid. They’re at low risk, but the risk from the vaccine is lower still.

Obviously there’s plenty more investigation to be done, but it seems the sensible conclusion is that getting AZ is safer than getting no vaccine, but a different vaccine would be safer than AZ. So the decision on whether to use AZ is probably down to availability of other vaccines and how dependent rollout is on AZ.

Lesalare · 06-04-2021 11:24PM

LLMMLL wrote: »

I honestly think that article is not going to help you. It has zero information on AZ vaccine or any other vaccine. Unless you’re a medical expert with a specialty in RP or vaccines then how will you use that article to assess your risk? How will you know if the issues talked about in that article are been vaguely related to the issues a tiny number of people face after a vaccine?

What would you advise a relative with RP to do?

I am concerned regarding the many European country bans due to clots and the fact I am someone with a - somewhat unfamiliar to many but mainly misunderstood - vascular disease.

I'm not reading that to find out anything re. AZ vaccine, I am doing so to find out if I am more prone to blood clots.

And including my RP (Raynaud's Phenomenon) issue and the fact my father died from a stroke.

I don't think it's unusual for anyone in my situ to be concerned and wanting to get as much info as I can.

LLMMLL · 06-04-2021 11:36PM

Lesalare wrote: »

I am concerned regarding the many European country bans due to clots and the fact I am someone with a - somewhat unfamiliar to many but mainly misunderstood - vascular disease.

I'm not reading that to find out anything re. AZ vaccine, I am doing so to find out if I am more prone to blood clots.

And including my RP (Raynaud's Phenomenon) issue and the fact my father died from a stroke.

I don't think it's unusual for anyone in my situ to be concerned and wanting to get as much info as I can.

I understand you’re concerned. But that article will tell you nothing. If you are more prone to a certain type of blood clot the very rare clotting that happens with AZ could be a completely different mechanism.

You have no way of interpreting that article in any reliable way.

If you don’t want to get the vaccine don’t get it. But it would be more rational to acknowledge to yourself that you are not qualified to assess the risk and that anxiety is the major driving factor in your decision. Which is absolutely fine. We make decisions based on anxiety all the time.

Lesalare · 06-04-2021 11:44PM

LLMMLL wrote: »

I understand you’re concerned. But that article will tell you nothing. If you are more prone to a certain type of blood clot the very rare clotting that happens with AZ could be a completely different mechanism.

You have no way of interpreting that article in any reliable way.

If you don’t want to get the vaccine don’t get it. But it would be more rational to acknowledge to yourself that you are not qualified to assess the risk and that anxiety is the major driving factor in your decision. Which is absolutely fine. We make decisions based on anxiety all the time.

As I said - I wasn't reading that article re the AZ Covid Vaccine. I read it and was doing so to learn the correlation between RP and clots.

I want to get vaccinated - of course I do. I have been moaning to mates how longs its going to take here.

I'm not making out I am in 'any more qualified to assess any risk - akin to an experienced 'medical professional'.

But after reading the numerous up and down differing reports on the blood clotting issues re AZ in last week or two globally, I am certainly not going to take something jabbed into me if I think I might become one of the statistics other people think they have no correlation to.

I have a right to protect myself too given my medical situation.

It's got nothing to do with 'Anxiety' - It's about common sense and weighing up what won't possibly kill me quicker.

LLMMLL · 06-04-2021 11:48PM

Lesalare wrote: »

As I said - I wasn't reading that article re the AZ Covid Vaccine. I read it and was doing so to learn the correlation between RP and clots.

I want to get vaccinated - of course I do. I have been moaning to mates how longs its going to take here.

I'm not making out I am in 'any more qualified to assess any risk - akin to an experienced 'medical professional'.

But after reading the numerous up and down differing reports on the blood clotting issues re AZ in last week or two globally, I am certainly not going to take something jabbed into me if I think I might become one of the statistics other people think they have no correlation to.

I have a right to protect myself too given my medical situation.

Absolutely but how are you going to assess your risk?

In a way it sounds like you’re decided. You won’t be getting AZ. Because what can be said that would lessen your worry? Can you envision any medical advice in the next few weeks that would change your mind?

Because there’s no way they’ll have any specific study on vaccines and RP by the time you’re offered the vaccine.

Lesalare · 06-04-2021 11:49PM

LLMMLL wrote: »

Absolutely but how are you going to assess your risk?

In a way it sounds like you’re decided. You won’t be getting AZ. Because what can be said that would lessen your worry? Can you envision any medical advice in the next few weeks that would change your mind?

Because there’s no way they’ll have any specific study on vaccines and RP by the time you’re offered the vaccine.

Well I have 3-4 months to look into it and work it out/make a decision.

LLMMLL · 06-04-2021 11:52PM

Lesalare wrote: »

It's got nothing to do with 'Anxiety' - It's about common sense and weighing up what won't possibly kill me quicker.

Of course it’s about anxiety. You’re not qualified to assess your risk. That’s not an insult. Most of us aren’t qualified either.

What other reason can there be to ignore expert advice on risk other than anxiety?

If you actually acknowledge that your concerns are based on anxiety then you will be making an informed decision, even if that decision is an anxiety-based-no. Whereas if you believe you’ve made a neutral educated risk assessment (which for some reason is the opposite of that recommended by those who are qualified to assess risk) then it’s a truly uninformed decision.

What exactly is happening with AstraZeneca?

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