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Covid 19 Part XXXI-187,554 ROI (2,970 deaths) 100,319 NI (1,730 deaths)(24/01)Read OP

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  • Closed Accounts Posts: 3,023 ✭✭✭Gruffalux


    Convalescent Plasma has continuously failed clinical trials in terms of outcomes so not sure why it would be effective against a new variant

    It has had mixed results which is not the same as ''continuously failed''...

    Mixed results links -

    https://journals.sagepub.com/doi/full/10.1177/1559325820979921

    https://www.hiqa.ie/reports-and-publications/health-technology-assessment/convalescent-plasma-treatment-covid-19

    https://www.nejm.org/doi/full/10.1056/NEJMoa2031304

    https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(20)30289-3/fulltext


  • Registered Users, Registered Users 2 Posts: 4,043 ✭✭✭Polar101


    Are blood plasma treatments for Covid in widespread use, or do you have to be a president of the US to receive such treatments?


  • Registered Users, Registered Users 2 Posts: 5,611 ✭✭✭10000maniacs


    Ohmeha wrote: »
    We've just recently gone on 7 day rolling averages from 275 daily reported cases to 6,050 daily reported cases (+ truckload missed) in just 6 weeks. New cases have to go sub 100

    Well... people had to celebrate Christmas. I mean get a grip!
    (I am being facetious and sarcastic here if you don't realise.)


  • Moderators, Entertainment Moderators, Society & Culture Moderators Posts: 14,279 Mod ✭✭✭✭pc7


    some of the other vaccines that are in development don't focus on the spike protein, right?

    Yeah, I’m sure Luke O’Neill the other day said one of them doesn’t, open to correction but I’m nearly sure he said it. Hopefully I’m remembering right, would be on the podcast from earlier this week. He also talked about how pfeizer could be tweaked within 6 weeks (again if remembering right).


  • Registered Users, Registered Users 2 Posts: 9,523 ✭✭✭runawaybishop


    pc7 wrote: »
    Yeah, I’m sure Luke O’Neill the other day said one of them doesn’t, open to correction but I’m nearly sure he said it. Hopefully I’m remembering right, would be on the podcast from earlier this week. He also talked about how pfeizer could be tweaked within 6 weeks (again if remembering right).

    Yeah, Pfizer ceo said 6 weeks for a new vaccine. It's one of the major advantages of mRNA


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  • Registered Users, Registered Users 2 Posts: 16,139 ✭✭✭✭niallo27


    Gael23 wrote: »
    Hospitality likely closed until June

    Whaaaaaaa. No this can't be right surely, be parties all over the country.


  • Posts: 6,192 ✭✭✭ [Deleted User]


    Yeah, Pfizer ceo said 6 weeks for a new vaccine. It's one of the major advantages of mRNA

    But surely such a vaccine would require same level of testing etc

    Though i guess it would be a long down road of development to start with


  • Registered Users, Registered Users 2 Posts: 12,780 ✭✭✭✭ninebeanrows


    I think the public will toe the line through March, I cant see there being any appetite after April, considering how we were sold the September pup last year, people wont be fooled this year. Society will largely open up by late April, maybe with exception of wet pubs and nightclubs until but later


  • Closed Accounts Posts: 3,023 ✭✭✭Gruffalux


    Yeah, Pfizer ceo said 6 weeks for a new vaccine. It's one of the major advantages of mRNA

    The tweaking is not as handy as it may seem - first there is the wait while they are tweaked, the wait for re manufacture, then there is the relaunch of another huge logistically-demanding vaccination program to revaccinate, then there is the next tweak, the confusion over which one one already has been given, etc etc and how many very recently-developed vaccines should people be getting in a set period of time anyway?

    The vaccines and the tweaking promises are effectively stopping us from making Plan Bs.

    Stamp the fecker out and be done with it.


  • Registered Users, Registered Users 2 Posts: 1,272 ✭✭✭theballz


    I think the public will toe the line through March, I cant see there being any appetite after April, considering how we were sold the September pup last year, people wont be fooled this year. Society will largely open up by late April, maybe with exception of wet pubs and nightclubs until but later

    Can’t see nightclubs reopening this year tbh


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  • Posts: 0 [Deleted User]


    But surely such a vaccine would require same level of testing etc

    Though i guess it would be a long down road of development to start with

    The EMA have already said it wouldn't.


  • Closed Accounts Posts: 12,653 ✭✭✭✭Plumbthedepths


    Gruffalux wrote: »
    The tweaking is not as handy as it may seem - first there is the wait while they are tweaked, the wait for re manufacture, then there is the relaunch of another huge logistically-demanding vaccination program to revaccinate, then there is the next tweak, the confusion over which one one already has been given, etc etc and how many very recently-developed vaccines should people be getting in a set period of time anyway?

    The vaccines and the tweaking promises are effectively stopping us from making Plan Bs.

    Stamp the fecker out and be done with it.

    So basically Zero Covid which has been dismissed multiple times on this thread and the reasons explained also multiple times.


  • Registered Users, Registered Users 2 Posts: 698 ✭✭✭SuperRabbit


    So basically Zero Covid which has been dismissed multiple times on this thread and the reasons explained also multiple times.


    well if this thread has spoken then i guess that's it!


  • Closed Accounts Posts: 3,023 ✭✭✭Gruffalux


    So basically Zero Covid which has been dismissed multiple times on this thread and the reasons explained also multiple times.

    That's fine, Plumb. People can dismiss it all they want. I am used to being the weirdo with the ideas no one likes :) If I was in New Zealand, though, I would probably be elected their Empress.


  • Moderators, Recreation & Hobbies Moderators Posts: 12,460 Mod ✭✭✭✭igCorcaigh


    Society should have sacraficed a bit more over Christmas.

    Society instead chose that sacrafices buy party's and stupidity. Society's decisions will be listened to and restrictions won't be eased for big events.

    A cold decision should be made based on case numbers and hospitalisation numbers and rates.

    It wasn't society, it was business interests. Money.


  • Closed Accounts Posts: 12,653 ✭✭✭✭Plumbthedepths


    well if this thread has spoken then i guess that's it!

    Actually the government has spoken , posters here happen to be in agreement with government.


  • Closed Accounts Posts: 12,653 ✭✭✭✭Plumbthedepths


    Gruffalux wrote: »
    That's fine, Plumb. People can dismiss it all they want. I am used to being the weirdo with the ideas no one likes :) If I was in New Zealand, though, I would probably be elected their Empress.

    They already have an Empress plus the advantage of being an island hours away from their nearest neighbours. Don’t worry you share the same ideas as Ryan and Staines to name but two.


  • Registered Users, Registered Users 2 Posts: 9,523 ✭✭✭runawaybishop


    Gruffalux wrote: »
    The tweaking is not as handy as it may seem - first there is the wait while they are tweaked, the wait for re manufacture, then there is the relaunch of another huge logistically-demanding vaccination program to revaccinate, then there is the next tweak, the confusion over which one one already has been given, etc etc and how many very recently-developed vaccines should people be getting in a set period of time anyway?

    The vaccines and the tweaking promises are effectively stopping us from making Plan Bs.

    Stamp the fecker out and be done with it.

    Nonetheless, 6 weeks to tweak it is far better than the initial months to develop a new vaccine.


  • Moderators, Recreation & Hobbies Moderators Posts: 12,460 Mod ✭✭✭✭igCorcaigh


    niallo27 wrote: »
    Whaaaaaaa. No this can't be right surely, be parties all over the country.

    There's going to be some party once this is over.
    But I don't think it'll be an all at once moment.

    Still, I can't wait. Can you imagine!


  • Closed Accounts Posts: 3,023 ✭✭✭Gruffalux


    Actually the government has spoken , posters here happen to be in agreement with government.

    It would be great if there was an actual plebiscite -
    a)do you want Zero Covid, a la the Australian method
    or
    b) do you want endless years of tweaking vaccines that you gotta shoot up regularly while hoping nothing really bad comes out of the remote jungle in the meantime?


    giphy.gif


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  • Closed Accounts Posts: 3,023 ✭✭✭Gruffalux


    They already have an Empress plus the advantage of being an island hours away from their nearest neighbours. Don’t worry you share the same ideas as Ryan and Staines to name but two.

    A better Empress!


  • Closed Accounts Posts: 12,653 ✭✭✭✭Plumbthedepths


    Gruffalux wrote: »
    It would be great if there was an actual plebiscite -
    a)do you want Zero Covid, a la the Australian method
    or
    b) do you want endless years of tweaking vaccines that you gotta shoot up regularly while hoping nothing really bad comes out of the remote jungle in the meantime?


    giphy.gif

    So
    (A ) close the borders for years ( slight problem with the six counties.
    (B) close the borders for ever in case something comes out of the jungle.
    I’m not getting a sense of in-depth thought here in your proposal to be honest.


  • Closed Accounts Posts: 3,023 ✭✭✭Gruffalux


    So
    (A ) close the borders for years ( slight problem with the six counties.
    (B) close the borders for ever in case something comes out of the jungle.
    I’m not getting a sense of in-depth thought here in your proposal to be honest.

    That is a dishonest representation of the more successful countries who have managed to keep Covid lowest in the populations. They have used strict quarantine and border control not closure. Which is the very best thing to do when a new virus is about.
    We have pretty much fcuked it up... to be honest. Thank goodness Covid was not a more serious illness because we would have been bovine in our handling of it. And the best that can be offered now is endlessly tweaked repeated vaccines for an endemic disease - yeah, that does not sound like an in-depth thought-out solution to me.
    And by the way there are other people besides mad yahoos who advocate for not allowing Covid circulate overly much in a population. There are places also besides New Zealand. Places like Vietnam, Thailand, Cambodia. Hong Kong. Places that are not islands. Places that have land borders.


  • Registered Users, Registered Users 2 Posts: 2,150 ✭✭✭TonyMaloney


    So basically Zero Covid which has been dismissed multiple times on this thread and the reasons explained also multiple times.

    It's quite endearing in a way that you think you won that argument.


  • Closed Accounts Posts: 12,653 ✭✭✭✭Plumbthedepths


    Gruffalux wrote: »
    That is a dishonest representation of the more successful countries who have managed to keep Covid lowest in the populations. They have used strict quarantine and border control not closure. Which is the very best thing to do when a new virus is about.
    We have pretty much fcuked it up... to be honest. Thank goodness Covid was not a more serious illness because we would have been bovine in our handling of it. And the best that can be offered now is endlessly tweaked repeated vaccines for an endemic disease - yeah, that does not sound like an in-depth thought-out solution to me.
    And by the way there are other people besides mad yahoos who advocate for not allowing Covid circulate overly much in a population. There are places also besides New Zealand. Places like Vietnam, Thailand, Cambodia. Hong Kong. Places that are not islands. Places that have land borders.
    Where’s the dishonesty? I responded to your comment mentioning Australia.
    As for the other countries you mention you may examine the cultural aspect of those societies versus typical western society.


  • Registered Users, Registered Users 2 Posts: 2,404 ✭✭✭mcburns07


    I think the public will toe the line through March, I cant see there being any appetite after April, considering how we were sold the September pup last year, people wont be fooled this year. Society will largely open up by late April, maybe with exception of wet pubs and nightclubs until but later

    People also claimed that they'd never get away with another lockdown last May.

    Here we are months later doing the same thing again. Well not quite as strict as back then, we've still spent 10 of the last 14 weeks at level 5 with all the indications we've another 6 weeks to go before anything is relaxed.

    Kid yourself all you want but they'll decide what they decide and the vast majority will go along with it because there's no other option really.


  • Registered Users, Registered Users 2 Posts: 37,714 ✭✭✭✭BorneTobyWilde


    Dublin is the hitspit for sure.

    Need to go big up there.


  • Posts: 0 [Deleted User]


    Pubs open in June?

    Glass half full! That’s the spirit!


  • Registered Users, Registered Users 2 Posts: 1,187 ✭✭✭GeorgeBailey


    Dublin is the hitspit for sure.

    Good moo-ning


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  • Posts: 0 [Deleted User]


    igCorcaigh wrote: »
    It wasn't society, it was business interests. Money.

    You're naive if you don't think those things are intertwined. People weren't forced into shops, restaurants, pubs or eachothers houses during December.


This discussion has been closed.
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