COVID-19: Vaccine/antidote and testing procedures Megathread [Mod Warning - Post #1]

3xh · 10-11-2020 11:26AM

stephenjmcd wrote: »

As I've said there's been plenty of technical discussion on this thread. You seem to be new to the thread, instead of watching Bill Gates conspiracy theory videos might I suggest doing some actual research.

Hopefully your stay on thread is short lived and we can get back to reasonable discussion

Tbh, in time, I’d love to be shown the full manufacturing process and ingredients used in this vaccine, why those particular ingredients are used, their actual effect on the immune system etc. Layman’s terms. No corporate fluff. No, ‘it’s a vaccine. What’s not to like? Just take it’ stuff.

If any of you proponents come across such, I’d be happy to take the time to read it.

tobefrank321 · 10-11-2020 11:32AM

Big question here is do we have super low temperature facilities in Ireland and if not what are the government's plans to build them?

I presume the HSE are already planning for the logistics.

Gael23 · 10-11-2020 11:32AM

So maybe a system of GP referrals to testing centres?

Still a huge organisational effort that I don’t have trust on the HSE to do. Referrals would need to be triaged to ensure they fit the criteria and that they have 2 vaccines for everyone

lbj666 · 10-11-2020 11:33AM

Deleted User wrote: »

Not conspiracy theory videos of Bill Gates, just interviews with Bill Gates himself and his well documented investment trail :pac:

I'm not here to argue with you anyway. Good luck with your (multiple dose) RNA vaccine for that deadly virus with a 0.03% of killing you.

Ah yes the classic conspiracy/cynics play of no of death/total population instead of no. of death/no. of cases to get an exaggerated low mortality rate.

Leftwaffe · 10-11-2020 11:35AM

I have absolutely zero faith on the HSE getting the distribution of this right when it comes to it. Zero.

tobefrank321 · 10-11-2020 11:35AM

Deleted User wrote: »

Here you go. Dr Carrie Madej breaks down the Gates vaccine. She seems a bit concerned. All copies were removed from YouTube, for some strange reason :rolleyes:

You perhaps all should give this a watch considering this is what will be entering your bodies.

I think you are in the wrong forum tbh.

And personally I don't care if vaccine makers make huge profits off this. You have to reward innovation otherwise there'd never be a vaccine.

10-11-2020 11:36AM

lbj666 wrote: »

And?

And.. you arrive back at my first answer of "it'll be as many doses as possible to extract as much money from you as possible".

tobefrank321 · 10-11-2020 11:38AM

Redordeadqwwer wrote: »

I have absolutely zero faith on the HSE getting the distribution of this right when it comes to it. Zero.

Based on everything related to covid 19 so far, you are probably right.

I'm just waiting for them to tell us in a couple months time, "stored at -70 degrees? First we heard of it".

By the sounds of it, this vaccine will require substantial logistical support and a plan. And so far NPHET and the HSE are at the "cautiously optimistic" stage.

10-11-2020 11:39AM

tobefrank321 wrote: »

I think you are in the wrong forum tbh.

And personally I don't care if vaccine makers make huge profits off this. You have to reward innovation otherwise there'd never be a vaccine.

It's a video of a Doctor explaining the components of the proposed vaccine, along with some concerns she has. I'd say that's relevant to a Coronavirus vaccination discussion, wouldn't you?

As always, people can watch and make up their own minds.

10-11-2020 11:41AM

tobefrank321 wrote: »

I'm just waiting for them to tell us in a couple months time, "stored at -70 degrees? First we heard of that".

:D:D

stephenjmcd · 10-11-2020 11:42AM

[Deleted User] wrote: »

Here you go. Dr Carrie Madej breaks down the Gates vaccine. She seems a bit concerned. All copies were removed from YouTube, for some strange reason :rolleyes:

You perhaps all should give this a watch considering this is what will be entering your bodies.

Ah yes the Dr subject to false and misleading claims articles. A great source.

"She also claims - without any evidence - that vaccines will "hook us all up to an artificial intelligence interface".

https://www.bbc.com/news/53525002

Here is the forum your looking for

https://touch.boards.ie/forum/576

charlie14 · 10-11-2020 11:42AM

Deleted User wrote: »

Not conspiracy theory videos of Bill Gates, just interviews with Bill Gates himself and his well documented investment trail :pac:

I'm not here to argue with you anyway. Good luck with your (multiple dose) RNA vaccine for that deadly virus with a 0.03% of killing you.

So basically you are anti vaccine and if Bill Gates wasn`t involved in a search for a vaccine it would be something something else.
Thanks for at least making that clear.

Le Bruise · 10-11-2020 11:45AM

Deleted User wrote: »

Here you go. Dr Carrie Madej breaks down the Gates vaccine. She seems a bit concerned. All copies were removed from YouTube, for some strange reason :rolleyes:

You perhaps all should give this a watch considering this is what will be entering your bodies.

I'm starting to think that you're not even a real Doctor....

lbj666 · 10-11-2020 11:45AM

Deleted User wrote: »

Here you go. Dr Carrie Madej breaks down the Gates vaccine. She seems a bit concerned. All copies were removed from YouTube, for some strange reason :rolleyes:

You perhaps all should give this a watch considering this is what will be entering your bodies.

You know your weren't too absurb with the suggesting that investors might want a return on it,
or that multiple vaccines give a a sustained return on investment and maybe there would be a bigger push for them instead of one off.

But then you had to post up that bat****, Human 2.0??

I think we are done with you mate, conspiracy theory forum is that away.

ixoy · 10-11-2020 11:46AM

tobefrank321 wrote: »

By the sounds of it, this vaccine will require substantial logistical support and a plan. And so far they are NPHET and the HSE are at the "cautiously optimistic" stage.

Pfizer seem to be taking over the logistical elements all the way up to the point it enters a country - taking on the storage shipping containers, hardened medical vials, etc.
After that, there will indeed be an issue around cold storage and I see even some well equipped US hospitals couldn't, right now, store the vaccine in sufficient quantities. They're planning on buying more but will the HSE even bother forward planning six months ahead? Will they just buy the one freezer for an initial batch? Or will they hold out hope for vaccines stored at room temperature (which might not be the most effective ones)?

ACitizenErased · 10-11-2020 11:48AM

DHL, FedEx and UPS have been tasked with developing cold storage transport. Based on what I've seen, it's ready to be activated within a few hours notice.

dominatinMC · 10-11-2020 11:51AM

Christ, where are the moderators when you need them! I was expecting the usual barrage of rubbish, but didn't expect the thread to get derailed so soon!

lbj666 · 10-11-2020 11:52AM

ACitizenErased wrote: »

DHL, FedEx and UPS have been tasked with developing cold storage transport. Based on what I've seen, it's ready to be activated within a few hours notice.

Once is it isn't Fastways I dont care. They'd throw them into the doctors garden in a melted cooler box.

tobefrank321 · 10-11-2020 11:53AM

ACitizenErased wrote: »

DHL, FedEx and UPS have been tasked with developing cold storage transport. Based on what I've seen, it's ready to be activated within a few hours notice.

If they can transport it a -70 degrees, that's impressive.

I'd be confident there are some facilities in Ireland which can store it at such low temperatures. I think the super low termperature might be a long term requirement, whereas if you plan to use the vaccine within a few days, temperatures close to 0 will do.

To be honest, I'd like to see a plan from NPHET or HSE, which would put us all at ease and not leave us with the usual worries around HSE planning.

Russman · 10-11-2020 11:53AM

Redordeadqwwer wrote: »

I have absolutely zero faith on the HSE getting the distribution of this right when it comes to it. Zero.

You're probably right. Maybe its the cynic in me, but I can almost imagine the HSE praying for one of the other candidates that doesn't require super cold storage to come through soon so they can avoid this one. Or I have visions of some lad in the HSE purchasing department asking Power City for a quote for a few freezers.

On a more serious note, I'm just wondering if suitable storage units actually exist that would be small enough for a GP's surgery ?
Would the cost of providing one of these for every GP be higher/lower/similar than getting the army to set up large vaccination centres ? Would the GPs need special training to administer the shot ?
No idea, just thinking out loud really about the logistics. If it turned out to be a shot that was needed every year, the vaccination centres would need to be permanent I suppose.

ACitizenErased · 10-11-2020 11:54AM

Just using FedEx as an example:

The Pfizer vaccine requires two doses, about three weeks apart. It also requires a deep-freeze cold chain, which FedEx Corp. and other logistics companies have been working to create.

FedEx is ready to move vaccines once they’re released for distribution, FedEx Express president, The Americas, Richard W. Smith said on “60 Minutes” Sunday, Nov. 8.

Smith said he was confident in FedEx’s ability to deliver vaccines while dealing with the holiday peak shipping season on top of a e-commerce surge COVID-19 created back in March.

“We’re prepared to delivery to every ZIP Code in this country,” Smith said.

“I’d be crazy if I didn’t say this was a herculean effort and recognize how monumental it is and may yet be.”

FedEx has modified its facilities for ultra-cold storage to be able to handle the requirements of the Pfizer vaccine. The company operates a network of 90 cold chain facilities in the Americas, Europe, Asia and Australia, including one that opened in 2016 at the FedEx Express Memphis hub.

https://dailymemphian.com/article/17984/fedex-to-deliver-pfizer-vaccine-effective-against-covid-19

stephenjmcd · 10-11-2020 11:55AM

tobefrank321 wrote: »

If they can transport it a -70 degrees, that's impressive.

I'd be confident there are some facilities in Ireland which can store it at such low temperatures. I think the super low termperature might be a long term requirement, whereas if you plan to use the vaccine with a few days, temperatures close to 0 will do.

To be honest, I'd like to see a plan from NPHET or HSE, which would put us all at ease and not leave us with the usual worries around HSE planning.

I did read somewhere and will try to dig it up that if being used within 24hrs a normal cooler will suffice after its been taken out of cold storage, if being used within a few hours room temp will be fine after taken out of cold storage.

Russman · 10-11-2020 11:55AM

ixoy wrote: »

Pfizer seem to be taking over the logistical elements all the way up to the point it enters a country - taking on the storage shipping containers, hardened medical vials, etc.
After that, there will indeed be an issue around cold storage and I see even some well equipped US hospitals couldn't, right now, store the vaccine in sufficient quantities. They're planning on buying more but will the HSE even bother forward planning six months ahead? Will they just buy the one freezer for an initial batch? Or will they hold out hope for vaccines stored at room temperature (which might not be the most effective ones)?

That's my fear tbh.

tobefrank321 · 10-11-2020 11:56AM

ACitizenErased wrote: »

Just using FedEx as an example:

https://dailymemphian.com/article/17984/fedex-to-deliver-pfizer-vaccine-effective-against-covid-19

Big corporations really stepping up!

Lets hope governments and healthcare systems also meet the challenge.

Hmmzis · 10-11-2020 11:59AM

CureVac's phase 1 paper has been uploaded:

https://www.medrxiv.org/content/10.1101/2020.11.09.20228551v1.full.pdf+html

Very small doses, looks like the highest one (12ug) is the only one that's good enough and that's the one they're going with for phase 2/3. From the mention of them testing out 16ug and 20ug doses it seems they might be thinking that the 12ug might not be all that great.

The graphs on the last page are interesting, they show convalescent people getting the smaller two doses (2ug and 4ug), the boost to their antibody titers is quite impressive and it looks like it's fine to just give one dose (4ug).

begbysback · 10-11-2020 12:00PM

[Deleted User] wrote: »

Here you go. Dr Carrie Madej breaks down the Gates vaccine. She seems a bit concerned. All copies were removed from YouTube, for some strange reason :rolleyes:

You perhaps all should give this a watch considering this is what will be entering your bodies.

Woo hoo, human 2.0 here we come, all those self help books, all that money spent on therapy in an attempt to self improve, and now all we have to do is get a rna jab, marvellous.

Gael23 · 10-11-2020 12:06PM

I suppose there will have to be a public procurement process full of red tape to navigate before freezers are purchased

Russman · 10-11-2020 12:08PM

I think this has been posted earlier in this thread but interesting all the same....

https://www.wsj.com/articles/pfizer-sets-up-its-biggest-ever-vaccination-distribution-campaign-11603272614

opinionated3 · 10-11-2020 12:08PM

CNN reporting the sinovac vaccine on trial in Brazil has been put on hold due to a "serious adverse event". Wonder what that's about?

tobefrank321 · 10-11-2020 12:21PM

opinionated3 wrote: »

CNN reporting the sinovac vaccine on trial in Brazil has been put on hold due to a "serious adverse event". Wonder what that's about?

I believe someone died - BUT - there's no indication what group they were in or what they died from.

Its obvious when you have tens of thousands enrolled that at least one person is likely to die from something.

There's a good chance it had nothing to do with the vaccine.

Edit - Death was unrelated to the trial.

https://news.sky.com/story/coronavirus-brazil-halts-trial-of-sinovac-vaccine-after-unrelated-death-of-volunteer-12128957

COVID-19: Vaccine/antidote and testing procedures Megathread [Mod Warning - Post #1]

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