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COVID-19: Vaccine/antidote and testing procedures Megathread [Mod Warning - Post #1]

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  • Closed Accounts Posts: 2,950 ✭✭✭polesheep


    1641 wrote: »
    May not be entirely safe or effective.


    And what might "entirely" safe mean? Some vulnerable groups cannot take existing vaccines. It is not a choice for them. And some who can take it show limited response.

    It is for these reason that it is so important that the "non-vulnerable" take such vaccines so as to develop population herd immunity.

    Obviously there are those who will not be able to take the vaccine. The point I was making is that once the vulnerable in general has had the vaccine the world will move on from restrictions. In time, sufficient numbers may take the vaccine to ensure herd immunity, but things will move on regardless.


  • Registered Users, Registered Users 2 Posts: 2,242 ✭✭✭brisan


    If the HSE & Dept of health haven't got some sort of plan in place then heads should roll. They'll need defence forces logistics to give them help with it probably

    Assuming we get enough doses of the vaccine to give it to those that need it
    Only 1 Billion doses
    That wont go far in China ,India ,Africa and Europe not to mention the United States


  • Registered Users, Registered Users 2 Posts: 15,897 ✭✭✭✭Goldengirl


    Again, a non-sequiter, a pro-vaccine country would be much more likely allow non vaccinated visitors as the risk to their population and healthcare capticy is virtually non-existant.

    I think it's really time to remove these points from the discussion - they are verging on anti-vaxx teritory in reverse.

    No. Countries that are pro vaccine will not be wanting to take that risk . By increasing the population of those without vaccination / or a negative test incoming , it is increasing the infection risk for those citizens who may be unable to take a vaccine , or who need more frequent doses to maintain immunity than the general population.
    This would be a proportion of older people along with those people with immune deficiency.
    Your last point I don't get because are you saying our points are pro vaccine ( double negative ) which I agree they are ?
    So why should our points be removed and not yours ?


  • Moderators, Business & Finance Moderators, Science, Health & Environment Moderators, Society & Culture Moderators Posts: 51,690 Mod ✭✭✭✭Stheno


    brisan wrote: »
    Assuming we get enough doses of the vaccine to give it to those that need it
    Only 1 Billion doses
    That wont go far in China ,India ,Africa and Europe not to mention the United States

    China have 2 vaccines of their own


  • Registered Users, Registered Users 2 Posts: 48,081 ✭✭✭✭Mitch Connor


    brisan wrote: »
    Assuming we get enough doses of the vaccine to give it to those that need it
    Only 1 Billion doses
    That wont go far in China ,India ,Africa and Europe not to mention the United States

    Are Phfizer the only ones that can make this vaccine?

    I get they are the ones that are researching it, but will they be keeping the IP to themselves to stop others from producing it? There are also other vaccines in the works - surely they don't all just stop now and they would also have an amount of dosses. Also, at a base level, will Phfizer be responsible for supplying everyone on the planet or will other regions/countries take from someone else (China taking a china dev'd one?)


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  • Registered Users, Registered Users 2 Posts: 12,917 ✭✭✭✭iguana


    Stheno wrote: »
    China have 2 vaccines of their own

    And are in talks with some other countries to distribute the Sinopharm vaccine which reduces the demand for the Pfizer/Biontech vaccine. As well as that, I suspect we'll also be getting some pretty good news on Oxford/AstraZeneca in the coming weeks if not days. That's another candidate that's been in mass production for months, so will hopefully mean many hundred of millions more people can be vaccinated as in 2021.


  • Moderators, Business & Finance Moderators, Science, Health & Environment Moderators, Society & Culture Moderators Posts: 51,690 Mod ✭✭✭✭Stheno


    iguana wrote: »
    And are in talks with some other countries to distribute the Sinopharm vaccine which reduces the demand for the Pfizer/Biontech vaccine. As well as that, I suspect we'll also be getting some pretty good news on Oxford/AstraZeneca in the coming weeks if not days. That's another candidate that's been in mass production for months, so will hopefully mean many hundred of millions more people can be vaccinated as in 2021.

    I think Oxford have also partnered with an Indian vaccine producer who have huge capacity to make vaccine doses and are already doing so


  • Closed Accounts Posts: 4,550 ✭✭✭ShineOn7


    Are Phfizer the only ones that can make this vaccine?

    I get they are the ones that are researching it, but will they be keeping the IP to themselves to stop others from producing it? There are also other vaccines in the works - surely they don't all just stop now and they would also have an amount of dosses. Also, at a base level, will Phfizer be responsible for supplying everyone on the planet or will other regions/countries take from someone else (China taking a china dev'd one?)


    I haven't been following it as much as some here, but I believe the Oxford, Johnson & Johnson and Moderna ones are looking very strong as well


  • Closed Accounts Posts: 651 ✭✭✭440Hertz


    There’s a general consensus that successful vaccines will be licenced and rapidly scaled up.

    For the EU, US and wealthy parts of Asia, this really is a very achievable goal. We have access to all of the technology and production capabilities and public & private infrastructure to do it.

    It’ll still take time though & production facilities are complex. The challenges here aren’t financial, they’re practical and to a large degree will be political / social when it comes to vaccine conspiracy theories.

    The one thing in the developed world is the resources being thrown at this are basically unlimited. There’s no shortage of funds or willingness to do whatever it takes to make it work.

    For poorer parts of the world, it’s going to be a much bigger challenge and realistically, even if it’s just out of self interest more than altruism, it needs to be funded as a global programme for those who can’t get access.


  • Posts: 2,827 ✭✭✭ [Deleted User]


    brisan wrote: »
    Assuming we get enough doses of the vaccine to give it to those that need it
    Only 1 Billion doses
    That wont go far in China ,India ,Africa and Europe not to mention the United States
    India and Africa don't need the vaccine as their populations don't have long enough lifespans. This is a virus that predominately affects Geriatrics in the western world despite all the scaremongering in the media.


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  • Moderators, Business & Finance Moderators, Science, Health & Environment Moderators, Society & Culture Moderators Posts: 51,690 Mod ✭✭✭✭Stheno


    440Hertz wrote: »
    There’s a general consensus that successful vaccines will be licenced and rapidly scaled up.

    For the EU, US and wealthy parts of Asia, this really is a very achievable goal. We have access to all of the technology and production capabilities and public & private infrastructure to do it.

    For poorer parts of the world, it’s going to be a much bigger challenge and realistically, even if it’s just out of self interest more than altruism, it needs to be funded as a global programme for those who can’t get access.

    There's a whole WHO program to help poorer nations funded by the richer nations


  • Registered Users, Registered Users 2 Posts: 1,919 ✭✭✭simongurnick


    lbj666 wrote: »
    Big question, if Pfizer say 90% reduction in infections, does that mean the 10% that do get infected can still get the same severity of the disease or would it be diminished also, its kind of a can you get half (or 10%) pregnant sort of question.

    I mentioned before that the mortality rate here for +65 is around 1 in 8 probably improving to 1 in 10, if the vaccine just improves that to 1 in 100, its still significant an not reason to let the virus run rampant.

    So, I don't know the exact details of this vaccine, so maybe shouldn't comment. But as a comparison, two of my kids needed a vaccine against RSV every year, which is a particularly nasty respiratory virus that can be fatal to immune comprised and/or medically complex children. My boys still contracted the virus despite the vaccine, but it was not as severe as if they had no vaccine. If they got a full blown whack of that virus they most likely would have tied.
    So, hopefully this one operates in a similar manner, where although not completely elimianting covid, will reduce its effects.

    Cheers all. Nice to hear some good news on a Monday morning.


  • Registered Users, Registered Users 2 Posts: 1,510 ✭✭✭woejus


    India and Africa don't need the vaccine as their populations don't have long enough lifespans. This is a virus that predominately affects Geriatrics in the western world despite all the scaremongering in the media.


    lolwut?


  • Posts: 0 [Deleted User]


    Stheno wrote: »
    I think Oxford have also partnered with an Indian vaccine producer who have huge capacity to make vaccine doses and are already doing so

    Johnson & Johnson too. They have monstrous capacity. They're planning a billion doses by end of next year.


  • Closed Accounts Posts: 232 ✭✭AssetBacked2


    brisan wrote: »
    Assuming we get enough doses of the vaccine to give it to those that need it
    Only 1 Billion doses
    That wont go far in China ,India ,Africa and Europe not to mention the United States

    There's a billion people in Europe and the U.S.A. Africa does not need a vaccine as their populations are not old enough. Asia doesn't need a vaccine from Pfizer as they already have a couple Chinese vaccines.

    So a billion doses from Pfizer alone covers all of the healthcare staff and vulnerable people in Europe and the U.S.A.


  • Closed Accounts Posts: 651 ✭✭✭440Hertz


    Stheno wrote: »
    There's a whole WHO program to help poorer nations funded by the richer nations

    Which should now be easier due to the change of US president. Trump had gone out of his way to both undermine the WHO, withdrew the US from it and even tried to buy out vaccine developers in Europe etc etc

    Hopefully, we should now see a major player re-engaging with multilateral organisations like the WHO.


  • Registered Users, Registered Users 2 Posts: 662 ✭✭✭Private Joker


    lbj666 wrote: »
    Big question, if Pfizer say 90% reduction in infections, does that mean the 10% that do get infected can still get the same severity of the disease or would it be diminished also, its kind of a can you get half (or 10%) pregnant sort of question.

    I mentioned before that the mortality rate here for +65 is around 1 in 8 probably improving to 1 in 10, if the vaccine just improves that to 1 in 100, its still significant an not reason to let the virus run rampant.

    The ceo of Pfizer said they don't know as its a blind study by independent research. And that data hasn't been made available to them.


  • Closed Accounts Posts: 651 ✭✭✭440Hertz


    You’ll also likely see a serious vaccine from Sanofi in the next few months and they have huge capacity as probably the world’s largest vaccine producer.

    You’re looking at a multi year scenario where these vaccines will go from breakthrough to being as common as your basic childhood vaccinations and that’s the point where this era comes to a close.

    More and more capacity and more vaccines will come on stream.


  • Registered Users, Registered Users 2 Posts: 12,149 ✭✭✭✭Gael23


    The next NPHET Briefing will be a good watch. Good news doesn’t fit the rhetoric


  • Registered Users, Registered Users 2 Posts: 14,426 ✭✭✭✭leahyl




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  • Registered Users, Registered Users 2 Posts: 15,897 ✭✭✭✭Goldengirl


    There's a billion people in Europe and the U.S.A. Africa does not need a vaccine as their populations are not old enough. Asia doesn't need a vaccine from Pfizer as they already have a couple Chinese vaccines.

    So a billion doses from Pfizer alone covers all of the healthcare staff and vulnerable people in Europe and the U.S.A.

    Just because a population is young does not mean they don't need it , there are older, vulnerable people and healthcare workers all over the world .


  • Closed Accounts Posts: 4,550 ✭✭✭ShineOn7


    Gael23 wrote: »
    The next NPHET Briefing will be a good watch. Good news doesn’t fit the rhetoric


    RTE must be scrambling to figure out how they can keep the Gloom Porn going with those who haven't worked them out yet


  • Posts: 2,827 ✭✭✭ [Deleted User]


    Goldengirl wrote: »
    Just because a population is young does not mean they don't need it , there are older, vulnerable people and healthcare workers all over the world .
    The point is that they won't consume a billion doses which are in short supply.
    They've got fewer Geriatrics and on a per capita ratio they generally have fewer health professionals.


  • Closed Accounts Posts: 232 ✭✭AssetBacked2


    Goldengirl wrote: »
    Just because a population is young does not mean they don't need it , there are older, vulnerable people and healthcare workers all over the world .

    Yes, it is a fact they don't need it. This virus affects a tiny percentage of young people. To say otherwise is to, quite frankly, display pure ignorance.


  • Closed Accounts Posts: 651 ✭✭✭440Hertz


    One of the issues with the BioNTech vaccine is the super low temp logistic chain. That’s feasible in Europe, the USA and elsewhere, but it’s more feasible in the developing world.


  • Registered Users, Registered Users 2 Posts: 2,004 ✭✭✭Hmmzis


    So, I don't know the exact details of this vaccine, so maybe shouldn't comment. But as a comparison, two of my kids needed a vaccine against RSV every year, which is a particularly nasty respiratory virus that can be fatal to immune comprised and/or medically complex children. My boys still contracted the virus despite the vaccine, but it was not as severe as if they had no vaccine. If they got a full blown whack of that virus they most likely would have tied.
    So, hopefully this one operates in a similar manner, where although not completely elimianting covid, will reduce its effects.

    Cheers all. Nice to hear some good news on a Monday morning.

    There is no licensed vaccine against RSV. What your children are getting is called monoclonal antibodies (mABs), passive immunization. The long life ones can persist for 6 to 12 months and protect from severe disease with 40-80% efficacy. They do not prevent infection in the case of RSV. The vaccines in the works against RSV should be doing better than that as they would stimulate the immune system itself to fight off the infection.


  • Registered Users, Registered Users 2 Posts: 2,027 ✭✭✭lbj666


    The point is that they won't consume a billion doses which are in short supply.
    They've got fewer Geriatrics and on a per capita ratio they generally have fewer health professionals.

    Why do they have a younger population, wouldnt be anything to do health/ life expectancy no?


  • Registered Users, Registered Users 2 Posts: 32,136 ✭✭✭✭is_that_so


    The point is that they won't consume a billion doses which are in short supply.
    They've got fewer Geriatrics and on a per capita ratio they generally have fewer health professionals.
    Another charmer I see, full of love for humanity!


  • Posts: 2,827 ✭✭✭ [Deleted User]


    is_that_so wrote: »
    Another charmer I see!
    With regard to the topic in hand I am using the correct term. If I called them curmudgeons then I would be using the wrong term.


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  • Registered Users, Registered Users 2 Posts: 25,117 ✭✭✭✭Kermit.de.frog


    This is very positive development but there is a long winter ahead.

    At least people can see light at the end of the tunnel which will lift spirits.


This discussion has been closed.
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