COVID-19: Vaccine/antidote and testing procedures Megathread [Mod Warning - Post #1]

09-11-2020 02:19PM

Russman wrote: »

They might go close if Oxford and J&J come through too though, no ?

They won't be attempting to vaccinate the entire population.

ShineOn7 · 09-11-2020 02:19PM

cian68 wrote: »

Zoom shares have gone down 5.5% and cinemas and airlines are going up

Just checked and RyanAir are already up 12% at 15 euros per share. Weren't they like 16 euros in February? That's incredible that they're nearly valued at pre Covid prices already

If I'd a DeGiro account I'd jump on Cruise ship companies today too

Indestructable · 09-11-2020 02:21PM

I actually got shivers when I read the headline and article. Amazing and historic work.

Gael23 · 09-11-2020 02:21PM

Airlines and hotels up be 15-20%

ShineOn7 · 09-11-2020 02:21PM

Itssoeasy wrote: »

No not yet.

It’s Finally a ray of light and what’s been a mess of a year in many ways and hopefully it all goes well. I expected myself to be happier but I’m being over cautious.

Yes same here

There's a few turns left in this I think, but it's great news overall

holdyerhorses · 09-11-2020 02:22PM

Deleted User wrote: »

My background is pharmacology, and used to work in regulatory affairs. My knowledge of vaccine trials is limited but as far as I can tell this is a somewhat spectacular result for a first vaccine. Sample size is more than adequate.

And tell me this - can we 'trust' the results. I mean if something is spectacular for a first vaccine, it would rightly raise and eyebrow and need detailed scrutiny. Given the bias towards doing something to alleviate this crisis, is there a danger here.

Itssoeasy · 09-11-2020 02:23PM

ShineOn7 wrote: »

Yes same here

There's a few turns left in this I think, but it's great news overall

And I feel ****e for not being more upbeat about it. I’m not trying to rain on the parade as it were. But yeah as I said it’s something positive and hopefully a light at the end of the tunnel.

ShineOn7 · 09-11-2020 02:24PM

D.Q wrote: »

This is the moment all the lunatics descend on this thread. We've prepared for this, remember your training

:pac:

Genuinely laughed out loud

Kerry25x · 09-11-2020 02:25PM

Definitely something to feel hopeful for, thanks for sharing!

09-11-2020 02:25PM

holdyerhorses wrote: »

And tell me this - can we 'trust' the results. I mean if something is spectacular for a first vaccine, it would rightly raise and eyebrow and need detailed scrutiny. Given the bias towards doing something to alleviate this crisis, is there a danger here.

I wouldn't doubt the results in any way. The controls in place are remarkably strong. Trial is double blinded and the results are assessed by independent scientists.

09-11-2020 02:29PM

holdyerhorses wrote: »

And tell me this - can we 'trust' the results. I mean if something is spectacular for a first vaccine, it would rightly raise and eyebrow and need detailed scrutiny. Given the bias towards doing something to alleviate this crisis, is there a danger here.

Just to add, from my limited knowledge I was hoping for above 75%, 90 and above was something I doubted would happen. If the others have similar levels the western world might feel normal again by next summer. Fingers crossed.

speckle · 09-11-2020 02:34PM

[Deleted User] wrote: »

I wouldn't doubt the results in any way. The controls in place are remarkably strong. Trial is double blinded and the results are assessed by independent scientists.

Maybe you or anyone could answer two questions for me?

First.. Were the participants tested before they started the trial for both antibodies and T cells etc against covid? As this new type of vaccination is meant to produce both?

Secondly how many in general, and in particular do these new results come from people in the high risk catagorys. As they are meant to be first to recieve it? Will the efficency lower in them, if all the above in the trial are healthy subjects?

thanks

average_runner · 09-11-2020 02:35PM

holdyerhorses wrote: »

And tell me this - can we 'trust' the results. I mean if something is spectacular for a first vaccine, it would rightly raise and eyebrow and need detailed scrutiny. Given the bias towards doing something to alleviate this crisis, is there a danger here.

There is a danger to every vaccine, but you won't know what it is for another 10 years.

People can decide if they want it or not. but countries might but restrictions on your travel if you don't have it

Mr.Nice Guy · 09-11-2020 02:41PM

There are other vaccines in development so there is cause for optimism. It will take time to roll them out and there are challenges in storing them but if we can avoid another winter like this next year then that in itself will be a significant improvement. Marvellous accomplishment by all those involved and an encouraging day for the world. 2020 is really turning a corner of late.

ACitizenErased · 09-11-2020 02:42PM

I always post this video when there’s vaccine news. Rollout is ready to go, including cold storage.

https://www.youtube.com/watch?v=byW1GExQB84

Vicxas · 09-11-2020 02:43PM

2020 is coming in strong with the plot twist late in the chapter.

Blondini · 09-11-2020 02:43PM

What's the best case scenario timeframe for availability in Ireland?

09-11-2020 02:44PM

speckle wrote: »

Maybe you or anyone could answer two questions for me?

First.. Were the participants tested before they started the trial for both antibodies and T cells etc against covid? As this new type of vaccination is meant to produce both?

Secondly how many in general, and in particular do these new results come from people in the high risk catagorys. As they are meant to be first to recieve it? Will the efficency lower in them, if all the above in the trial are healthy subjects?

thanks

I don't think there were any people tested for either (don't think there is any accurate one for t cells in any event) but it wouldn't be relevant to the trial results as neither vaccine or placebo group were tested and the sample size was big enough that if pre existing immunity was a factor it would be an equal factor across both groups and would have no significant impact on the trial result.

I haven't seen any data on risk groups yet. We will have to wait on see for that one I think.

holdyerhorses · 09-11-2020 02:46PM

average_runner wrote: »

There is a danger to every vaccine, but you won't know what it is for another 10 years.

People can decide if they want it or not. but countries might but restrictions on your travel if you don't have it

'It' - what's it? There are multiple vaccines in similar trials.

And I've made this point before - but countries putting restrictions on people being vaccinated is nonsensical/illoigcal and purely a political talking point, not scientific...For travel, once the vulnerable population of your jurisdiction are vaccinated, the primary reason for restrictions (healthcare capacity) disappears.

funnydoggy · 09-11-2020 02:47PM

Now the government should roll out its education campaign on the safety of vaccines, especially the upcoming few.

... If they have one.

09-11-2020 02:47PM

Blondini wrote: »

What's the best case scenario timeframe for availability in Ireland?

Seems 50 million is the worldwide number before Christmas, based on the EU preorder i think the EU allocation will be 15 to 20 million, we might get somewhere between 100,000 to 200,000 before the end of the year. All very rough figures.

holdyerhorses · 09-11-2020 02:48PM

Deleted User wrote: »

I don't think there were any people tested for either (don't think there is any accurate one for t cells in any event) but it wouldn't be relevant to the trial results as neither vaccine or placebo group were tested and the sample size was big enough that if pre existing immunity was a factor it would be an equal factor across both groups and would have no significant impact on the trial result.

I haven't seen any data on risk groups yet. We will have to wait on see for that one I think.

"Vaccine candidate was found to be more than 90% effective in preventing COVID-19 in participants without evidence of prior SARS-CoV-2 infection in the first interim efficacy analysis"

Cordell · 09-11-2020 02:49PM

average_runner wrote: »

There is a danger to every vaccine, but you won't know what it is for another 10 years.

People can decide if they want it or not. but countries might but restrictions on your travel if you don't have it

You generally know immediately, in minutes, hours or maybe days. 10 years is vaccines causing autism territory.

average_runner · 09-11-2020 02:50PM

holdyerhorses wrote: »

'It' - what's it? There are multiple vaccines in similar trials.

And I've made this point before - but countries putting restrictions on people being vaccinated is nonsensical/illoigcal and purely a political talking point, not scientific...For travel, once the vulnerable population of your jurisdiction are vaccinated, the primary reason for restrictions (healthcare capacity) disappears.

It is side effects. Takes a few years to find out about some of these.
But we go to move on and get out of this mess.

I think countries will still be careful next year, maybe all people travelling takes a test in the airport if a 20 min one is around if you don't have the vaccine.

To be honest under 50 won't see the vaccine at least till the 2nd half of next year

Anyhow its a good day with some very good news

timsey tiger · 09-11-2020 02:50PM

ShineOn7 wrote: »

Plus two doses of it are needed

But! Some regions of the world have pretty much Zero Covid anyway or are heading that way. New Zealand and Oz for example

South East Asia have stamped on it so hard that case numbers there are tiny compared to the EU and America. And haven't parts of Africa got a very small amount of cases?

So I'm guessing all that will play into it too

Who knows at this stage eh?

NZ etc. still need vaccine, they won't want to remain isolated forever, as it really only needs one person coming in with it to start the whole thing off again

titan18 · 09-11-2020 02:50PM

Deleted User wrote: »

Seems 50 million is the worldwide number before Christmas, based on the EU preorder i think the EU allocation will be 15 to 20 million, we might get somewhere between 100,000 to 200,000 before the end of the year. All very rough figures.

Ya, and with needing 2 doses, that's half the people who get vaccinated. I'd be hopeful though by March/April, we might have enough people vaccinated that life can go back to some normality. Probably still have masks and social distancing but maybe the rest will ease

Eric Cartman · 09-11-2020 02:52PM

Should give it to prisoners first so we can send them back into prisons without endangering prison staff, after that move to other high risk groups like direct provision, migrant centres etc...

it'll give the public reassurance and solve infection blackspot issues.

09-11-2020 02:52PM

holdyerhorses wrote: »

"Vaccine candidate was found to be more than 90% effective in preventing COVID-19 in participants without evidence of prior SARS-CoV-2 infection in the first interim efficacy analysis"

They would have done a medical questionnaire asking if they had previously been infected, and excluded if they answered yes. As far as I know they did not test for antibodies on participants but I'd have to look at the trial structure again, I may have missed that.

Level 42 · 09-11-2020 02:53PM

Gael23 wrote: »

RTÉ on it now

Rte obsessed with the minks they ain't happy with the vaccine

polesheep · 09-11-2020 02:53PM

titan18 wrote: »

Ya, and with needing 2 doses, that's half the people who get vaccinated. I'd be hopeful though by March/April, we might have enough people vaccinated that life can go back to some normality. Probably still have masks and social distancing but maybe the rest will ease

Why would we have masks and social distancing if enough people have been vaccinated to let life go back to normal?

COVID-19: Vaccine/antidote and testing procedures Megathread [Mod Warning - Post #1]

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