COVID-19: Vaccine/antidote and testing procedures Megathread [Mod Warning - Post #1]

Stheno

ixoy wrote: »

Nice to see her address the 70% efficacy report too. RTE still doing a glass half empty on the headline, whereas most other news sources see it as more positive at this point (some having adjusted earlier headlines).

She explained it really clearly too which was great

Gael23

Do we know how long the vaccine takes to work once administered?

tobefrank321

Gael23 wrote: »

Do we know how long the vaccine takes to work once administered?

6 weeks from first dose for two dose vaccine seems to be the norm. Vulnerable groups would probably still need to shield for those 6 weeks.

stephenjmcd

Gael23 wrote: »

Do we know how long the vaccine takes to work once administered?

Which one ?

28 days seems to be what most are going for

tfeldi

ixoy wrote: »

Nice to see her address the 70% efficacy report too. RTE still doing a glass half empty on the headline, whereas most other news sources see it as more positive at this point (some having adjusted earlier headlines).

I read the article but it still doesn't make sense - at least not to me. They are saying that 1.5 doses work better than 2 doses? What is the reason for this?

XsApollo

I’d be thinking it’s more how your immune system responds to the first dose , then when the second dose comes your immune system attacks it it and makes it less effective.
Where as a smaller first does won’t illicit such an aggressive response from your immune system.

JDD

If immunity from the vaccine only lasts 12 months (or worse, less than that) how is that going to pan out? I can't see everyone who is happy to get the vaccine first time around rocking up to their local pharmacy every 18 or 12 or 10 months to get a second round. Even less so if it's a jab (everyone hates needles) and if you have to attend twice in four weeks.

Are we going to have a problem if immunity isn't a decent amount of time, like around 2-5 years? Or is it fine as long as HCW and over 80's get the vaccine every time they need it?

Maybe we're hoping the virus will mutate to something less crappy and the vaccine will become redundant over time anyway? Am I right in saying that might never happen though, especially since it seems that this coronavirus isn't prone to regular mutations?

Gael23

JDD wrote: »

If immunity from the vaccine only lasts 12 months (or worse, less than that) how is that going to pan out? I can't see everyone who is happy to get the vaccine first time around rocking up to their local pharmacy every 18 or 12 or 10 months to get a second round. Even less so if it's a jab (everyone hates needles) and if you have to attend twice in four weeks.

Are we going to have a problem if immunity isn't a decent amount of time, like around 2-5 years? Or is it fine as long as HCW and over 80's get the vaccine every time they need it?

Maybe we're hoping the virus will mutate to something less crappy and the vaccine will become redundant over time anyway? Am I right in saying that might never happen though, especially since it seems that this coronavirus isn't prone to regular mutations?

It might be long enough to break transmission and allow it to die out

hmmm

JDD wrote: »

If immunity from the vaccine only lasts 12 months (or worse, less than that) how is that going to pan out?

It was mentioned earlier in the thread that Slaoui who is head of "Operation Warp Speed" in the US was predicting that protection from the virus might be relatively short (1 to a few years), but protection from the disease might be long term. I think that's similar to the prediction some time ago that vaccines might help to reduce this to a head cold for most people.

We'll also have antibody treatments ready to go if it does flare up. We can't give them to millions of people, but if we get an outbreak affecting a few hundred every now and again they could be used.

CIARAN_BOYLE

tfeldi wrote: »

I read the article but it still doesn't make sense - at least not to me. They are saying that 1.5 doses work better than 2 doses? What is the reason for this?

With some vaccines a small hit followed by a heavy hit helps the immune system ramp up for a fight.

Two heavy hits can just make the immune system give up.

JDD

hmmm wrote: »

It was mentioned earlier in the thread that Slaoui who is head of "Operation Warp Speed" in the US was predicting that protection from the virus might be relatively short (1 to a few years), but protection from the disease might be long term. I think that's similar to the prediction some time ago that vaccines might help to reduce this to a head cold for most people.

We'll also have antibody treatments ready to go if it does flare up. We can't give them to millions of people, but if we get an outbreak affecting a few hundred every now and again they could be used.

Makes sense. Hopefully protection from the disease is long term. In any case, the current vaccines buy us time at the very least, for better vaccines with longer immunities to be developed.

tfeldi

CIARAN_BOYLE wrote: »

With some vaccines a small hit followed by a heavy hit helps the immune system ramp up for a fight.

Two heavy hits can just make the immune system give up.

Thank you.

ShineOn7

iguana wrote: »

Right now we still need to keep distancing, wearing masks, practicing good hygiene, etc

Given the HSE's track record surely it'll be longer than "right now" we need to do the above

I'm thinking more like another 6-10 months

Still though, I'm cautiously optimistic that this bástard virus will be slowly strangled throughout 2021

ShineOn7

froog wrote: »

3 vaccines on the verge of being approved in less than a year. amazing achievement.

Depending on how next year goes, I think what has been done with these vaccines is among the top 5 scientific achievements ever by humans

Imagine what could be done if they push all that will into other things once we have Covid strangled

Gael23

Regarding immine compromised patients , I was with my gastroenterologist this morning abs he said any vaccine is five once it’s not live

funnydoggy

Gael23 wrote: »

Regarding immine compromised patients , I was with my gastroenterologist this morning abs he said any vaccine is five once it’s not live

Pfizer / Moderna would be good to go in that case then!

Duke of Url

ShineOn7 wrote: »

Depending on how next year goes, I think what has been done with these vaccines is among the top 5 scientific achievements ever by humans

Imagine what could be done if they push all that will into other things once we have Covid strangled

Maybe start with the flu which has less then 50% success rate and still kills millions each year

ZX7R

Tread moving quite quickly apologizes if its been ask,
Just wondering if a child is in a vulnerable group ,would they be able to access to the vaccination.
Or will it be available to children at all

fred funk }{

ZX7R wrote: »

Tread moving quite quickly apologizes if its been ask,
Just wondering if a child is in a vulnerable group ,would they be able to access to the vaccination.
Or will it be available to children at all

Children are at the opposite end of the vulnerable spectrum.

Call me Al

fred funk }{ wrote: »

Children are at the opposite end of the vulnerable spectrum.

Not all children are perfectly healthy unfortunately.

hmmm

ZX7R wrote: »

Tread moving quite quickly apologizes if its been ask,
Just wondering if a child is in a vulnerable group ,would they be able to access to the vaccination.
Or will it be available to children at all

Some of the vaccines are being tested on 12-18 year olds but in small numbers - I don't know if the numbers are sufficient to allow them be approved in that age group.

I haven't heard of any testing in the under-12s.

Good question though, I'm not sure what the protocol will be where a child is in a particularly vulnerable group. Hopefully herd immunity can contribute to reducing risk.

fred funk }{

Call me Al wrote: »

Not all children are perfectly healthy unfortunately.

Apologies, I read the post wrong. Thought they meant children in general and not a child in a vulnerable group.

PCeeeee

Gael23 wrote: »

Regarding immine compromised patients , I was with my gastroenterologist this morning abs he said any vaccine is five once it’s not live

Good stuff Gael. Happy for ya

Frank Bullitt

Did a video call with my folks over the weekend. I live in Canada and this is the longest I have gone without going home. All the news of the vaccine makes me feel very happy and takes the sting out of the manic homesickness I have been getting lately.

There is the light I was hoping to see.

Steve012

Out of curiosity I'm posting this poll. I am completely non biased to peoples opinions and choices

bmc58

Steve012 wrote: »

Out of curiosity I'm posting this poll. I am completely non biased to peoples opinions and choices

Anyone who has any interest in the returning of some sort of normality to our world would take this vaccine.Thats my opinion.

Steve012

bmc58 wrote: »

Anyone who has any interest in the returning of some sort of normality to our world would take this vaccine.Thats my opinion.

Yes agreed, I'm non biased in this thread though so won't comment

daheff

There should be another option, yes but not immediately. I'd be in the wait and see how people get on 6-12 months after vaccination camp. These vaccines have been made at breakneck speed... without long term data.

Swine flu vaccine were similarly fast (although slower than these)....and a number of people have ended up with narcolepsy as a side effect.

All that said, I'd still be in the Take the Vaccine corner.

ShineOn7

Duke of Url wrote: »

Maybe start with the flu which has less then 50% success rate and still kills millions each year

That's the spirit!

Deeper Blue

Any chance the people voting no could explain why? Do you want to go back to normality or not?