COVID-19: Vaccine/antidote and testing procedures Megathread [Mod Warning - Post #1]

TomSweeney wrote: »

Well, I think you are making covid more dangerous than it is there, for the vast majority it's mild, up to 40% don't even know they have it , as time goes on and more data comes in we see the IFR trending down.

Vaccine trials are stopped if a single adverse reaction is found - that's out of 30,000 people.

Asymptomatic Covid - best stats I've seen is 18%. There has not been as many truly asymptomatic as people thought there may have been. There is more pre-symptomatic who when tested don't have symptoms, but they go on to develop them.

There was a really good Swiss study of Covid in Geneva which found an IFR of 0.14% in the 50-65 group, and 5.6% for those over 65. IFR is trending down only because our ability to treat it is getting better while ICUs are not overwhelmed, this is still a very dangerous disease.

TomSweeney wrote: »

OK good to know, so basically these trials going fine indicates a safe vaccine ?


the narcolepsy from the MERS vaccine, when did that appear ?

There is no MERS vaccine, just some candidates in phase1 or 2 trials. None have reported any issues.

Narcolepsy was reported in some rare instances after one of the H1N1 swine flu vaccines got administered. H1N1 is quite notorious for causing the odd auto-immune reaction, 1976 was another one where some GBS cases were attributed to the H1N1 vaccine. Of note here is the fact that all those vaccines have been of the inactivated type (killed virus) and since the 2009 Pamdermix issues all Western companies seem to be staying well far away from that type. The inactivation process can sometimes be a little hit and miss. I think only China and India are trying this method against SARS-cov-2.

That said, any serious side effects from vaccination are exceedingly rare.

Hmmzis wrote: »

There is no MERS vaccine, just some candidates in phase1 or 2 trials. None have reported any issues.

Narcolepsy was reported in some rare instances after one of the H1N1 swine flu vaccines got administered. H1N1 is quite notorious for causing the odd auto-immune reaction, 1976 was another one where some GBS cases were attributed to the H1N1 vaccine. Of note here is the fact that all those vaccines have been of the inactivated type (killed virus) and since the 2009 Pamdermix issues all Western companies seem to be staying well far away from that type. The inactivation process can sometimes be a little hit and miss. I think only China and India are trying this method against SARS-cov-2.

That said, any serious side effects from vaccination are exceedingly rare.

The Cambridge clinical trial doc Mark Toshner on a Twitter thread cited an incidence rate of 1/50k for narcolepsy in the H1N1 vaccine.

..and I was trying to work out the serious adverse reaction (including death) rates to HPV...that looks like a 1 in a million event.

ShineOn7 wrote: »

That's an incredible stat

Have you a source?

It was in the Lancet - https://www.thelancet.com/pdfs/journals/laninf/PIIS1473-3099(20)30584-3.pdf

lbj666 wrote: »

It's rare for a vacine to have any case of serious side effects and among those vacines the case extremely rare anyway.

Compare that to the odds of long covid or hospital.

They're my thoughts on vaccines too. According to the most widely shared IFR rates for covid, I have a 0.02% or 1/5000 chance of dying if I contract the virus. But my chances of dying from an adverse reaction to the vaccine are at least 200 times less again. Its a no-brainer.

tom1ie wrote: »

First off I just want to state I am in no way an anti vaxer, in fact I got the flu jab the same as every year, this year.
Before myself and my family chose to get the vaccine:
1) how do we know how long immunity will last
2)how can we possibly tell the long term side effects (if any) that could occur due to taking this vaccine plus any boosters if required?
Thanks.

I don’t think answers to either are known right now.
I’m taking the view that, I’m not vulnerable that I know of (touch wood !), so by the time I’ll be allowed get a vaccine there’ll be probably 6 more months of hopefully safe data.

Thierry12 wrote: »

0.0092 IFR, 20 - 49 age group

I have a greater chance of dieing in a car crash this year?

So if 1 million adults, 20 - 49 get Covid

92 will die

Where is the outrage?

Why do we have restaurants and businesses closed?

This is crazy if true

C’mon, you know full we’ll it’s not just about deaths. Look at the scenes in ICUs across Europe, that’s why businesses are closed.

Voltex wrote: »

https://www.nytimes.com/2020/11/17/health/coronavirus-immunity.html

Well that’s good news.

tom1ie wrote: »

First off I just want to state I am in no way an anti vaxer, in fact I got the flu jab the same as every year, this year.
Before myself and my family chose to get the vaccine:
1) how do we know how long immunity will last
2)how can we possibly tell the long term side effects (if any) that could occur due to taking this vaccine plus any boosters if required?
Thanks.

Hi tom1ie, how long does immunity from the flu vaccine last?

I mean immunity to the current strain in circulation not next years one? Given your answer to my first qustion, how do you time when in the flu season you get the flu vaccine?

Dr. on CNN reckoned Oxford/AstraZenica vaccine would be more the world vaccine. Easier to make large amounts and currently being made in India and Brazil, cost $3/4. The counter implication being Pfizer and Moderna more in the US.

timsey tiger wrote: »

Hi tom1ie, how long does immunity from the flu vaccine last?

I mean immunity to the current strain in circulation not next years one? Given your answer to my first qustion, how do you time when in the flu season you get the flu vaccine?

Immunity last one year right, but weakens as time goes on. When the new strain comes out you have to get a new vaccine.

I time getting the flu vaccine when I get my free flu voucher off work 😂

Water John wrote: »

Dr. on CNN reckoned Oxford/AstraZenica vaccine would be more the world vaccine. Easier to make large amounts and currently being made in India and Brazil, cost $3/4. The counter implication being Pfizer and Moderna more in the US.

Could be right. They’ve committed to the low price worldwide until the pandemic is over and indefinitely for developing countries, I think they’ve said for “low and middle income” countries.

90% efficacy and stored in a regular fridge - what’s not to like.

Voltex wrote: »

They're my thoughts on vaccines too. According to the most widely shared IFR rates for covid, I have a 0.02% or 1/5000 chance of dying if I contract the virus. But my chances of dying from an adverse reaction to the vaccine are at least 200 times less again. Its a no-brainer.

I had a grandparent who discovered in old age that he had effectively a dead lung all his life probably because of TB. He never knew he had TB. That's what scares me about Covid on a personal level, what we're likely to discover that the disease has done in some people 10 or 20 years down the line.

A vaccine to me is again a no-brainer. The small risk is balanced against the much larger risk from Covid.

Cork2021 wrote: »

Anti vax on claire Byrne!! RTE need to fûck off!!

They’ll come round when they try to book a flight to Spain next summer.

hmmm wrote: »

I had a grandparent who discovered in old age that he had effectively a dead lung all his life probably because of TB. He never knew he had TB. That's what scares me about Covid on a personal level, what we're likely to discover that the disease has done in some people 10 or 20 years down the line.

A vaccine to me is again a no-brainer. The small risk is balanced against the much larger risk from Covid.

Sooner the better in my view. I am happy to be in the first group getting the vaccine.

I hope that they will be able to stamp my vaccination booklet as I expect it will be linked to travel for many countries similar to yellow fever.