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The Cass Report has finally been peer reviewed

  • 28-05-2025 12:21PM
    #1
    Registered Users, Registered Users 2 Posts: 7,515 ✭✭✭


    It doesn't look good. 25 peers, including some from University of Galway, have completely eviscerated the Cass Report.

    https://www.researchgate.net/publication/391630681_Critically_appraising_the_cass_report_methodological_flaws_and_unsupported_claims

    Using the ROBIS tool, they found that all seven systematic reviews exhibit a high risk of bias citing issues such as ambiguous eligibility criteria, exclusion of non-English and qualitative studies, and inappropriate appraisal tools. Further, the primary research is critiqued for methodological deficiencies and unsubstantiated claims, particularly regarding trends in gender dysphoria diagnoses, transitions, and detransitions.

    The review argues that the Cass report misrepresents evidence, applies inconsistent quality standards and lacks sufficient justification for several policy-relevant conclusions, such as the ban on puberty blockers for minors.



Comments

  • Moderators, Science, Health & Environment Moderators Posts: 18,335 Mod ✭✭✭✭CatFromHue


    "Finally, and perhaps more fundamentally, evaluating the efficacy of GAC based on psychosocial well-being alone is misguided. e primary goal of GAC is to pre-vent or induce the appearance of certain physical char-acteristics, and their physiological efficacy is undisputed. Mental health benefits are a logical consequence of liv-ing authentically [82] and we noted previously that stud-ies included in the Cass review found positive effects of HRT on gender dysphoria, depression, and anxiety [47–50]"

    82: Adolescent Medical Transition is Ethical: An Analogy with Reproductive Health

    Florence Ashley

    Abstract

    In this article, I argue that adolescent medical transition is ethical by analogizing it to abortion and birth control. The interventions are similar insofar as they intervene on healthy physiological states by reason of the person's fundamental self-conception and desired life, and their effectiveness is defined by their ability to achieve patients' embodiment goals. Since the evidence of mental health benefits is comparable between adolescent medical transition, abortion, and birth control, disallowing transition-related interventions would betray an unacceptable double standard. While great enough risks can override autonomy over fundamental aspects of personal identity, I demonstrate that the available scientific evidence does not corroborate the view that adolescent medical transition is dangerous. Consequently, adolescent medical transition should be recognized as ethical and remain available."

    Oh boy, where do you start with that!!

    Studies 47, 48, and 49 are all low quality too.

    Even if you take everything at face value in this paper, which I'm not sure if you should, they're still not showing evidence for gender affirming care in minors.



  • Registered Users, Registered Users 2 Posts: 9,930 ✭✭✭volchitsa


    You forgot to check their ethics section ("competing interests" subsection)

    ”I enjoy cigars, whisky and facing down totalitarians, so am I really Winston Churchill?” (JK Rowling)



  • Registered Users, Registered Users 2 Posts: 2,297 ✭✭✭aero2k


    Double facepalm.jpg

    The Cass report was actually debunked a long time ago:

    http://chrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/https://law.yale.edu/sites/default/files/documents/integrity-project_cass-response.pdf

    Unfortunately, that debunking was comprehensively debunked in a very even-handed manner by Jesse Singal - it's easy to find in a quick Google. The document I've linked above only contains the credentials of the authors - it neglects to mention that the psychopathic monster Johanna Olson Kennedy is the best-known practitioner of youth gender medicine in the US and that Jack Turban is one of the leading figures in promoting gender affirming care. The whole document is hosted on Yale's website - presumably to give the air of authority to an unscientific document. The irony of it being done as part of "The Integrity Project" is delicious.

    The main finding of the Cass Review is that the evidence base for drug based treatments for adolescents experiencing gender dysphoria is weak. Now, it would be very easy to debunk that by producing one study with credible evidence to the contrary. That nobody has published such a study in the past 13 1/2 months tells its own story.



  • Registered Users, Registered Users 2 Posts: 9,930 ✭✭✭volchitsa


    This thread seems to have died a death.

    Pity, because another thing that's missing from their rapier analysis of the Cass report is any mention of how valid the ROBIS tool is anyway.

    Unsurprisingly, the answer is "Weeeelll…. it depends."

    Basically the main aim of the AMSTAR-2 is to assess the methodological quality of a review, while that of the ROBIS tool is to evaluate the level of bias present within a systematic review.

    The ROBINS-1 is "the preferred tool to assess risk of bias in Cochrane Reviews for non-randomized studies (NRS)". The second study tries to improve on that, by combining it with yet another tool, RoB2 - and still identifies flaws and limitations in the tools themselves.

    Yet a poster here thinks a single use of ONE tool, by a group of trans activist researchers, with no mention of any of the acknowledged limitations of the tool they've chosen, is worth the paper it's printed on.

    Far more likely is that this was the only way the activists could get the result they wanted, and that if they had genuinely been testing for bias, as opposed to organising their study so as to find bias, the study would have looked very different.

    ”I enjoy cigars, whisky and facing down totalitarians, so am I really Winston Churchill?” (JK Rowling)



  • Registered Users, Registered Users 2 Posts: 2,297 ✭✭✭aero2k


    I'm going to go out on a limb and suggest that the probability of finding someone independent who can totally undermine the conclusions in the Cass final report is vanishingly small. The efforts so far have been from people with significant skin in the game, but despite their sometimes impressive academic credentials, the results have been embarrassingly poor.



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  • Registered Users, Registered Users 2 Posts: 9,930 ✭✭✭volchitsa


    I've looked at it a bit more, and it's very noticeable that they confine themselves to criticising the report, but entirely fail to name a single study that, had it been included in the report, would have changed the conclusions.

    So they haven't debunked the findings at all. The evidence for giving puberty-blockers is objectively so weak as to be reckless. Several other countries (the Scandinavian ones in particular) have reached similar conclusions from their own research.

    If these people had managed to show otherwise, you may be sure they would have said so.

    I've also discovered that Natacha Kennedy, who's one of the authors, was found to be behind a smear campaign against academics who held differing views to hers.

    So - someone who can be relied on to be totally objective, right?

    (I wonder why @circadian seems to have so little interest in their own thread - have they posted in it at all after the OP?)

    ”I enjoy cigars, whisky and facing down totalitarians, so am I really Winston Churchill?” (JK Rowling)



  • Registered Users, Registered Users 2 Posts: 7,515 ✭✭✭circadian


    I'm watching the thread, however, life takes priority with a job, kids, one of whom has a rare genetic condition that takes a fair bit of monitoring. Don't take lack of posting as lack of interest.



  • Registered Users, Registered Users 2 Posts: 2,297 ✭✭✭aero2k


    Posters tend to pop up on all the threads any time Cass is mentioned, with the "Cass has been debunked" line, as if it was an established fact. None of them stick around to debate it.

    Edit: It's more posting along the lines of "things are as I say they are, because I say so."



  • Registered Users, Registered Users 2 Posts: 9,930 ✭✭✭volchitsa


    Except I looked before I posted that comment, and I saw you'd posted in other threads since then, so while I completely get that not everyone has the same amount of time available, it's clear that in terms or priorities, your own thread seems not to interest you much. Which is odd.

    Anyway, now you are here, do you have a comment about the problems that have been pointed up about this study that you thought debunked Cass, but doesn't?

    ”I enjoy cigars, whisky and facing down totalitarians, so am I really Winston Churchill?” (JK Rowling)



  • Registered Users, Registered Users 2 Posts: 7,515 ✭✭✭circadian


    This thread requires a deeper level of engagement than football or other light hearted social issues.



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  • Registered Users, Registered Users 2 Posts: 9,930 ✭✭✭volchitsa


    Absolutely. What's the point in posting an OP that's just a quote from the study and an unproven opinion on it then.

    Any chance of a comment now on the problems with it? You know, such as the fact that the authors are pretty much all trans activists, with serious ethical issues posed by at least one of them in that regard?

    Or the fact that they used a single tool which only considers whether the authors of the Cass report have followed their own protocol, and doesn't consider the value of the evidence itself? IOW a very partial analysis (which is why it's common in these cases to combine several such analytical tools, to improve results)?

    And more importantly, why they don't make any effort to show that had the study been done differently, the findings would have been different?

    ”I enjoy cigars, whisky and facing down totalitarians, so am I really Winston Churchill?” (JK Rowling)



  • Registered Users, Registered Users 2 Posts: 2,297 ✭✭✭aero2k


    I'm very sorry to hear about your child, I hope they are ok.

    As does choosing which study to chose to support your assertion about Cass being debunked.



  • Registered Users, Registered Users 2 Posts: 7,515 ✭✭✭circadian


    Firstly, I did not quote the study and provided a synopsis of my understanding. Secondly, yes, I had time at that point to read the study. Right now, I do not have time to delve into the responses and articles contained within.

    I am free to respond at a time that suits me and my life, without constantly being tagged, harangued and followed around the site to determine whether I am capable of putting time into reading several articles and papers to form a response.



  • Registered Users, Registered Users 2 Posts: 9,930 ✭✭✭volchitsa


    Indeed. So how did you choose that study to base your belief that Cass has been "completely eviscerated" on? What was it about it that convinced you? I'm wondering about this "deeper level of engagement": where is it?

    Because the more I look at this study, the more unreliable it seems.

    Latest thing: the author I mentioned just now, Natasha Kennedy, a trans activist who ran a smear campaign against academics who held differing opinions to her - almost all female academics of course - well get this:

    Goldsmiths College

    confirmed that she was an employee but would not explain which department she worked in or why she appeared to be listed twice in the staff directory: once as Mark Hellen, in the department of educational studies, and secondly as Natacha Kennedy, who is named in equality and diversity reports. Both profiles appear to be active.

    It also remained unclear why an academic paper on Ms Kennedy’s specialist subject of transgenderism in children, published by the Graduate Journal of Social Sciences in 2010, cited two co-authors: Natacha Kennedy and Mark Hellen.

    Neither Ms Kennedy nor Goldsmiths would clarify whether the paper was by two individuals or the same person. A spokesman said: “Goldsmiths prides itself on its inclusive community and is committed to the values of freedom of speech within the law.”

    Here it is: https://itgl.lu/wp-content/uploads/2015/04/Kennedy-and-Hellen-Transgender-Children.pdf

    Two authors, but in reality both seemingly the same person. Does the ethical integrity of someone doing a study into the, well, integrity, of a report matter at all?

    What does it say about the other authors of the report that they didn't see a problem with having this person on their team?

    And where are the non trans activists in the author-group? I mean, in a report looking for bias on a very contentious issue, wouldn't you expect them to at least try to have a range of opinions in their own group of authors? It's not as though there were only two of three of them.

    It's hard to avoid the conclusion that this "evisceration" of Cass is in fact a complete set-up intended to manufacture the conclusions it came to. And it didn't take a very deep level of engagement to identify those issues.

    ”I enjoy cigars, whisky and facing down totalitarians, so am I really Winston Churchill?” (JK Rowling)



  • Registered Users, Registered Users 2 Posts: 9,930 ✭✭✭volchitsa


    Of course you are, but one very weak OP and then nothing for 2 days, when you're posting elsewhere on the site is enough for posters to ask where you've gone, that's all. It's hardly harrassment.

    Because if you had time to read the study, how come you didn't notice any of the glaring issues with it? You chose that study and this thread - it's reasonable to ask you to explain your view of these issues. It's not like asking someone who just replied on a thread - you opened up the subject, and then apparently refused to discuss it.

    Anyway, never mind all that. Any chance you could reply to some of the questions raised now, seeing as you're back?

    (Who followed you round the site haranguing you? That would be a bit much, I agree.)

    ”I enjoy cigars, whisky and facing down totalitarians, so am I really Winston Churchill?” (JK Rowling)



  • Registered Users, Registered Users 2 Posts: 1,917 ✭✭✭Jack Daw


    Anybody that thinks that interrupting the natural growth cycle of a human being and not allowing them to go through puberty at the appropriate age is a good idea is an idiot.

    If people are having issues going through puberty they need to be helped through those issues by psychologists etc but stopping a child going through their natural growth cycle at the appropriate age is barbaric .

    And please don't mention precocious puberty in girls because the treatment for that just delays it for a few years while they are too young and then they can go through it at 12/13 like they normally would.



  • Registered Users, Registered Users 2 Posts: 9,930 ✭✭✭volchitsa


    Even for precocious puberty in girls, it's not a treatment free of risk of real harm: the risks are much the same (osteroporosis etc). It's just that the risk-benefit balance of a child going through puberty at 5 or 6, with a known increased risk of child sexual abuse and early pregnancy, not to mention social isolation from her peers who are on a different planet from her, is felt to weigh more heavily in favour of treatment than non treatment.

    Much of the above is related to the social pressure on girls from older men, which is ironic in this context for those of us who believe that gender is a construct imposed by society: girls are being given dangerous drugs to protect them from men wanting to have sex with them before they are able to deal with the consequences. So the idea of giving it to other children to make their perfectly healthy bodies fit a different construct is kind of tragic.

    ”I enjoy cigars, whisky and facing down totalitarians, so am I really Winston Churchill?” (JK Rowling)



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