What exactly is happening with AstraZeneca?

Jim_Hodge · 21-05-2021 09:39AM

brickster69 wrote: »

Malawi destroys 20K does that have expired. Fair enough but why let them expire or at least send them somewhere else in time.

https://twitter.com/BBCAfrica/status/1394974870145019906

They received them too late to get them all used. Not their fault but the WHO's.

ddarcy · 21-05-2021 10:39AM

is_that_so wrote: »

Now planned to be reduced to 12 weeks from May 24th.

https://www.irishtimes.com/news/health/gap-between-astrazeneca-doses-to-be-reduced-to-12-weeks-1.4570846

Also Reid has said

AstraZeneca "is not a choice vaccine" as it will be used for second doses so a strong signal that it will have little part to play down the line apart from that.

Nothing in that article has what you’ve said above. Not saying it hasn’t been changed. The only thing Reid said is that the choice based model is a departure from what was originally done.

I do agree that AZ is dead though if people can choose, I can also see no more NIAC changes as well, unless they allow as other countries are doing, the second dose of AZ to be an mRNA version. All planning ahead will have to be mRNA.

fly_agaric · 27-05-2021 11:04AM

Interest seems to have been lost in thread now that Covid-19 vaccine supply has improved across Europe, and boot can't really be put into the EU any more by Current affairs/IMHOs contingent of Euro-phobic cranks.

Some update on the legal action(s) taken by the EU - it appears to be seeking a high level of fines that could severly damage or destroy the company.

https://www.rte.ie/news/coronavirus/2021/0526/1223998-eu-astrazeneca-action/

Its legal team demanded an upfront fine of €10m plus "€10 per dose and per day of delay" in that event.

Also situation seem to have improved end of April/May as regards the AstraZeneca supply in the EU and its looking like company might be able to meet the lower target of 100m doses by 1st July (basing that on our total of 556k received up to 1st week in May and that being ~ 1% of EU total)

https://www.gov.ie/en/press-release/c3693-update-on-covid-19-vaccine-deliveries-12-may-2021/

odyssey06 · 27-05-2021 11:06AM

Copied from the main vaccine thread as it also relates to AZ

https://www.irishtimes.com/news/world/europe/german-scientists-claim-to-have-solved-covid-vaccine-blood-clot-puzzle-1.4576752

Scientists in Germany claim to have cracked the cause of the rare blood clots linked to the Oxford/AstraZeneca and Johnson & Johnson coronavirus vaccines and believe the jabs could be tweaked to stop the reaction happening altogether.

Stark · 27-05-2021 11:22AM

I wonder do they have to go through clinical trials/approval again if they tweak the spike protein RNA

brickster69 · 27-05-2021 01:56PM

" AstraZeneca said it informed the commission in a detailed production plan that the UK manufacturing chain would firstly be dedicated to British supplies. " which was 100 mln doses.

https://www.centralfifetimes.com/news/national-news/19329809.eu-seeks-big-fine-astrazeneca-court-case/

I wonder if they have a copy of that ?

https://twitter.com/Peter___Ward/status/1397684742976327684

Moyglish · 27-05-2021 03:01PM

Anyone that's had their first shot of AZ, do you know how/when you will be contacted with an appointment for your second dose?

Also, has anyone at this stage been offered to an alternative to AZ on their second appointment?

ingalway · 27-05-2021 04:25PM

Moyglish wrote: »

Anyone that's had their first shot of AZ, do you know how/when you will be contacted with an appointment for your second dose?

Also, has anyone at this stage been offered to an alternative to AZ on their second appointment?

I got a text on Sunday from HSE with my second appointment. Had the jab today, AZ again, no alternative offered.

drunkmonkey · 27-05-2021 09:00PM

Lisa Shaw trending.

Timberrrrrrrr · 27-05-2021 09:25PM

drunkmonkey wrote: »

Lisa Shaw trending.

Just for clarity

https://thrombosisuk.org/thrombosis-statistics.php

Thrombosis Statistics

Every 37 seconds someone in the western world dies from a venous thromboembolism (VTE)

Improving risk assessment and prevention -
1 in 4 people die from causes related to blood clots

Thrombosis

Thrombosis is the formation of a blood clot, known as a thrombus, within a blood vessel. It prevents blood from flowing normally through the circulatory system.

drunkmonkey · 27-05-2021 09:46PM

Timberrrrrrrr wrote: »

Just for clarity

Yea you certainly clarified it, https://letmegooglethat.com/?q=Lisa+Shaw&l=1

deeperlearning · 27-05-2021 09:46PM

It was madness to give an AstraZeneca vaccine to Lisa Shaw.

The risks of a blood clot occurring in a 44 year-old woman after taking the AstraZeneca vaccine are far too high.

drunkmonkey · 27-05-2021 10:08PM

That's what Oxfords own risk calculator says, but Timberrrrrrrr has made an excellent point there proving without any shadow of a doubt it was just bad timing.

27-05-2021 10:23PM

Timberrrrrrrr wrote: »

Just for clarity

https://thrombosisuk.org/thrombosis-statistics.php

Thrombosis

Someone does not die every 37 seconds from a CVST, which appears to be what happened to Lisa Shaw.

Wolf359f · 27-05-2021 10:27PM

drunkmonkey wrote: »

That's what Oxfords own risk calculator says, but Timberrrrrrrr has made an excellent point there proving without any shadow of a doubt it was just bad timing.

Timberrrrrrrr is comparing different bloods clots which occur at different rates in the population. It may be easier to use the CDC term: thrombosis with thrombocytopenia syndrome (TTS) to avoid confusion with less fatal and more common 'everyday' clots seen in the general public.

Dyr · 27-05-2021 10:28PM

fly_agaric wrote: »

Interest seems to have been lost in thread now that Covid-19 vaccine supply has improved across Europe, and boot can't really be put into the EU any more by Current affairs/IMHOs contingent of Euro-phobic cranks.
]

Oh deary me.

We shall see what the court has to say about the whole fiasco. Decision expected within a month. Will there be even more blushes in store for the Commission?

drunkmonkey · 27-05-2021 10:33PM

Wolf359f wrote: »

Timberrrrrrrr is comparing different bloods clots which occur at different rates in the population. It may be easier to use the CDC term: thrombosis with thrombocytopenia syndrome (TTS) to avoid confusion with less fatal and more common 'everyday' clots seen in the general public.

Surely you can't be suggesting he's misinterpreted the data, Timberrrrrrrr is one of our best fact checkers, say it ain't so.

Storm 10 · 27-05-2021 11:26PM

My Son is 36 in emergency service is due his 2nd jab next week his first was Astra Zenica will he be getting a different vaccine for his 2nd

drunkmonkey · 27-05-2021 11:48PM

Storm 10 wrote: »

He is in the fire service never had Covid

You don't know that and currently we can't test to prove it, FDA just approved a t-cell test but I'd say it'll be a while before it arrives here, I've mentioned Luke too many times today but from listening to him and reading between the lines if he had it previously he's immune system should have went into over drive after the first dose.

~Rebel~ · 28-05-2021 12:25AM

drunkmonkey wrote: »

You don't know that and currently we can't test to prove it, FDA just approved a t-cell test but I'd say it'll be a while before it arrives here, I've mentioned Luke too many times today but from listening to him and reading between the lines if he had it previously he's immune system should have went into over drive after the first dose.

It seems wise to proceed as if he hasn’t previously had Covid, without any evidence to the contrary though, right?

drunkmonkey · 28-05-2021 12:54AM

~Rebel~ wrote: »

It seems wise to proceed as if he hasn’t previously had Covid, without any evidence to the contrary though, right?

I'm not sure, antigen is active infection, PCR picks up previous 3mts but the t-cell test can go way back further we just don't have access to that type of testing yet.
If there was any problem in having had a previous infection then 2 jabs it should have shown up in health care workers as they've had a lot of previous infections.
As you said it seems to be wise to carry on regardless, no evidence to say anything different.

Polar101 · 28-05-2021 01:07AM

Storm 10 wrote: »

My Son is 36 in emergency service is due his 2nd jab next week his first was Astra Zenica will he be getting a different vaccine for his 2nd

No.

robinph · 28-05-2021 06:59AM

drunkmonkey wrote: »

You don't know that and currently we can't test to prove it, FDA just approved a t-cell test but I'd say it'll be a while before it arrives here, I've mentioned Luke too many times today but from listening to him and reading between the lines if he had it previously he's immune system should have went into over drive after the first dose.

That is just rumour and people trying to make sense of random reactions. Plenty of people who never had covid who had reactions, or who did have covid but didn't have reactions or any other variations of the reactions.

drunkmonkey · 28-05-2021 07:12AM

robinph wrote: »

That is just rumour and people trying to make sense of random reactions. Plenty of people who never had covid who had reactions, or who did have covid but didn't have reactions or any other variations of the reactions.

Sorry completely misread what you said, I'd 100% agree with you on that point.

stephenjmcd · 28-05-2021 07:15AM

Storm 10 wrote: »

My Son is 36 in emergency service is due his 2nd jab next week his first was Astra Zenica will he be getting a different vaccine for his 2nd

No he wont be, he'll be getting AZ

drunkmonkey · 28-05-2021 08:35AM

fly_agaric wrote: »

That is unknowable (by you) + also don't think it is great to be dishing out unsolicited medical advice on vaccination here.

I thought he was a HCW at the start which would have made the odds a log higher, the advice came from Luke O'Neill there's a link to the podcast discussing it above.
Testing is about to come on a lot so it'll be a lot easier see who had it. https://abcnews.go.com/Health/fda-authorizes-cell-test-game-changer-covid-19/story?id=76318248

28-05-2021 08:40AM

It is NOT Luke o'Neills advice for front line workers to avoid a 2nd dose
It is mine that they take it
The risk versus reward is microscopically small

drunkmonkey · 28-05-2021 08:54AM

Marine Layer wrote: »

It is NOT Luke o'Neills advice for front line workers to avoid a 2nd dose
It is mine that they take it
The risk versus reward is microscopically small

He was suggesting going from some study that a previous infection and one dose gives better protection than two doses and an infection.
Risk vs reward is wholly dependent on age and sex when it comes to AZ especially in women, we've had two high profile deaths in the UK in the last week or so both making headline news in the manistream media.

28-05-2021 09:00AM

drunkmonkey wrote: »

I thought he was a HCW at the start which would have made the odds a log higher, the advice came from Luke O'Neill there's a link to the podcast discussing it above.
Testing is about to come on a lot so it'll be a lot easier see who had it. https://abcnews.go.com/Health/fda-authorizes-cell-test-game-changer-covid-19/story?id=76318248

You don't just decide not to give someone a second dose because they might have had covid. There are plenty of frontline workers who haven't had it. You can't base vaccine policy on assumptions.

fly_agaric · 28-05-2021 09:09AM

drunkmonkey wrote: »

I thought he was a HCW at the start which would have made the odds a log higher, the advice came from Luke O'Neill there's a link to the podcast discussing it above.
Testing is about to come on a lot so it'll be a lot easier see who had it. https://abcnews.go.com/Health/fda-authorizes-cell-test-game-changer-covid-19/story?id=76318248

Interesting link, but none of that changes anything (as regards you not knowing whether a person got Covid or not).
I haven't listened to the podcast you mention so don't know if you are distorting it or not.
Just don't think it is right to effectively make medical suggestions to people about whether they should get a 2nd dose of vaccine or not, and to be frank I'd take anything you post on any subject (let alone something so serious) with a mine of salt.

What exactly is happening with AstraZeneca?

Comments