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Vaccine Megathread - See OP for threadbans

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  • Posts: 0 [Deleted User]


    OwlsZat wrote: »
    I asked a question. I asked was it as bad as it sounds. Not sure how the trend of variants reducing in England helps the discussion. I read this article and it doens't sounds great. I'd be delighted to hear how this isn't the case.


    https://www.rte.ie/news/world/2021/0513/1221323-india-virus-global/


    "The WHO added that the variant might also be resistant to vaccines, as a study reported sevenfold reduced effectiveness against antibodies released by Moderna and Pfizer vaccines."

    That's a misquote that's been doing the rounds. The WHO never said that. As for the second part a study showed a 7-fold reduction in neutralization. That DOES NOT mean 7 times less effective. All samples from vaccinated individuals were able to neutralize the virus.


  • Registered Users, Registered Users 2 Posts: 1,006 ✭✭✭revelman


    SJFly wrote: »
    Reports were coming out that the decision was imminent and then it seemed to be pushed out till next week. This seemed to coincide with more data coming out of the US. It's really hard to imagine them considering that data and then recommending J&J for women under 50, seeing as they are most at risk. We'll see what happens soon I guess.

    We don’t know that women under 50 are more at risk. All we know is that currently there are more women than men who have had this blood clot. We would need to know all sorts of things e.g. how many women vs how many men were given the vaccine in the first place? Could it be that more young healthcare workers (many of whom are women) received this vaccine in the US? This is what skewed the early numbers on AZ-associated clots in Germany and Norway.

    There was an interesting article in the Atlantic a few weeks ago where doctors were doubting that this would be a “women only” issue.


  • Registered Users, Registered Users 2 Posts: 3,004 ✭✭✭Van.Bosch


    TheDoctor wrote: »
    Did Wednesday numbers get released yet?

    No - assume the hack is impacting it.

    More worryingly, the GP referral system is down so cases may be impacted, unless they allow all test centres to be walk-in


  • Registered Users, Registered Users 2 Posts: 15,450 ✭✭✭✭stephenjmcd


    Van.Bosch wrote: »
    No - assume the hack is impacting it.

    More worryingly, the GP referral system is down so cases may be impacted, unless they allow all test centres to be walk-in

    Close contact system is also down


  • Registered Users, Registered Users 2 Posts: 3,131 ✭✭✭dominatinMC


    OwlsZat wrote: »
    I asked a question. I asked was it as bad as it sounds. Not sure how the trend of variants reducing in England helps the discussion. I read this article and it doens't sounds great. I'd be delighted to hear how this isn't the case.


    https://www.rte.ie/news/world/2021/0513/1221323-india-virus-global/


    "The WHO added that the variant might also be resistant to vaccines, as a study reported sevenfold reduced effectiveness against antibodies released by Moderna and Pfizer vaccines."
    Can file this under RTE - Variant - Hypothetical. Typical article from them. Yes, variants are to be monitored and any or all COULD be resistant but all evidence (real world, trials, etc) suggests that is not the case. Even Pfizer announced during the week that they will not be updating their vaccine for variants

    https://www.thejournal.ie/no-evidence-pfizer-vaccine-update-variants-5433235-May2021/


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  • Registered Users, Registered Users 2 Posts: 1,534 ✭✭✭OwlsZat


    If you look at the chart it clearly shows the rise in cases in areas where Indian variant is known to be circulating amongst the younger more unvaccinated population.

    Same rise not observed in older vaccinated population.

    The chart is nothing to do with reducing variant levels in the UK





    Sorry my regression analysis brain wasn't functioning. Great stuff. You two should be writing the rte.ie editor a quick email to update their nonsense.


  • Registered Users, Registered Users 2 Posts: 15,450 ✭✭✭✭stephenjmcd


    OwlsZat wrote: »
    Sorry my regression analysis brain wasn't functioning. Great stuff. You two should be writing the rte.ie editor a quick email to update their nonsense.

    I wouldn't wish that on anyone, they'd be there for a while correcting all the mistakes in articles. Standard of research is just awful


  • Registered Users, Registered Users 2 Posts: 3,348 ✭✭✭Rebelbrowser


    I wouldn't wish that on anyone, they'd be there for a while correcting all the mistakes in articles. Standard of research is just awful

    On the contrary, they know exactly what they are doing. Why do research when that would mean not being able to publish the click bait scare story they already have....


  • Registered Users, Registered Users 2 Posts: 3,131 ✭✭✭dominatinMC


    Ballynally wrote: »
    In England the numbers seem to have gone up from 200 last week to 900.
    Bolton, Glasgow, now in Northern Ireland and Ireland.
    VOC..
    Numbers, numbers, numbers. Are people getting sick/hospitalised/dying?


  • Posts: 1,159 [Deleted User]


    revelman wrote: »
    We don’t know that women under 50 are more at risk. All we know is that currently there are more women than men who have had this blood clot. We would need to know all sorts of things e.g. how many women vs how many men were given the vaccine in the first place? Could it be that more young healthcare workers (many of whom are women) received this vaccine in the US? This is what skewed the early numbers on AZ-associated clots in Germany and Norway.

    There was an interesting article in the Atlantic a few weeks ago where doctors were doubting that this would be a “women only” issue.

    With J&J, the data shows women under 50 at a higher risk.

    When it was resumed in the US a few weeks ago the stats were released. There was pretty much a 50/50 split between men and women in terms of recipients of the vaccines. Yet all of the cases at that point were in women.

    The latest reporting shows six cases in men, so it's not a woman only issue. The highest incidence rates are in women in their 30s and 40s though, and they're not far off the figures we're seeing for AZ in those groups.

    https://www.nbcnews.com/health/health-news/johnson-johnson-vaccine-linked-28-cases-blood-clots-cdc-reports-n1267128


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  • Registered Users, Registered Users 2 Posts: 8,106 ✭✭✭Christy42


    Hardyn wrote: »
    That's a misquote that's been doing the rounds. The WHO never said that. As for the second part a study showed a 7-fold reduction in neutralization. That DOES NOT mean 7 times less effective. All samples from vaccinated individuals were able to neutralize the virus.

    Indeed. Pretty disgraceful journalism from RTE on this one. They need to check their sources before publishing.


  • Posts: 0 [Deleted User]


    Mylady75 wrote: »
    I have been a long time lucker here on boards.
    My husband was registered in cohorts 4 but was never called so we registered him.by age and got his vaccine yesterday,
    which was astrazeneca and now have been told it will be 16 weeks before he gets his next one.
    I thought it was 12 do you think this might be lowered to 10 as it just seem so long till he is fully vaccinated we had been told that this was all he would get.
    Just so disappointed we have done everything right all along .
    I would not mind waiting a while but to be told 16 week it just seem forever

    The guidance is that those who received AZ vaccine are to be considered fully vaccinated 4 weeks post 1st dose


  • Registered Users, Registered Users 2 Posts: 2,027 ✭✭✭lbj666


    OwlsZat wrote: »
    Sorry my regression analysis brain wasn't functioning. Great stuff. You two should be writing the rte.ie editor a quick email to update their nonsense.

    Rte and others are not interested in finding more detail, if there is alarmist headline that can be made out of it they will do it. We've been talking about it in ad naseum here for months appreciate you might be new here.

    Some of my numbers by be off but from recollection;

    Antibodies dropping 7 fold doesnt mean a decrease of efficacy 7 fold. The mRNAs had a 6 fold drop in antibodies vs the SA variant but the efficacy was no way decreased in the same way think it drops 5-10% ish.

    It doesnt go into T cells either, which is the other means of defence particularly against sever illness, its not easy to test.

    AZ and JJ are a bit vaguer in its effectiveness but are indicators suggest they are far from useless and any commentator who suggests so in my eyes loses credibilty from the off.


  • Registered Users, Registered Users 2 Posts: 6,421 ✭✭✭Wolf359f


    revelman wrote: »
    We don’t know that women under 50 are more at risk. All we know is that currently there are more women than men who have had this blood clot. We would need to know all sorts of things e.g. how many women vs how many men were given the vaccine in the first place? Could it be that more young healthcare workers (many of whom are women) received this vaccine in the US? This is what skewed the early numbers on AZ-associated clots in Germany and Norway.

    There was an interesting article in the Atlantic a few weeks ago where doctors were doubting that this would be a “women only” issue.

    We do have a lot of data on J&J. Granted this is back from April, as I cannot find the updated charts to include the men who have had the same issue.
    JJ.jpg
    Doses are equally split between men and women, with the incidence in women 30-39 being the highest. As for young healthcare workers.... I'd have believe the vast majority of HCW's in the US were well vaccinated before J&J made it's first delivery!


  • Registered Users, Registered Users 2 Posts: 524 ✭✭✭penny piper


    The guidance is that those who received AZ vaccine are to be considered fully vaccinated 4 weeks post 1st dose

    I had an astra zenica vaccine last sunday and the doctor who vaccinated me told me it would be 16 weeks before I got the next one. My husband had got it the wednesday before and was told 12 weeks by a nurse. I told that to the doctor and he said they keep changing it.


  • Posts: 0 [Deleted User]


    Christy42 wrote: »
    Indeed. Pretty disgraceful journalism from RTE on this one. They need to check their sources before publishing.

    For anybody wondering where it began. Just shows how ridiculously easy it is to spread misinformation. WHO did correct the record but not before the horse was long gone.

    https://twitter.com/ronlondoncon/status/1391895711982264326?s=19


  • Registered Users, Registered Users 2 Posts: 1,006 ✭✭✭revelman


    Flying Fox wrote: »
    With J&J, the data shows women under 50 at a higher risk.

    When it was resumed in the US a few weeks ago the stats were released. There was pretty much a 50/50 split between men and women in terms of recipients of the vaccines. Yet all of the cases at that point were in women.

    The latest reporting shows six cases in men, so it's not a woman only issue. The highest incidence rates are in women in their 30s and 40s though, and they're not far off the figures we're seeing for AZ in those groups.

    https://www.nbcnews.com/health/health-news/johnson-johnson-vaccine-linked-28-cases-blood-clots-cdc-reports-n1267128

    I’m no scientist or statistician but the numbers we are talking about are so small (22 women and 6 men out of nearly 9 million), how can we be sure that women are more at risk?


  • Posts: 0 [Deleted User]


    I had an astra zenica vaccine last sunday and the doctor who vaccinated me told me it would be 16 weeks before I got the next one. My husband had got it the wednesday before and was told 12 weeks by a nurse. I told that to the doctor and he said they keep changing it.

    either way you are considered fully vaccinated after 4 weeks and maintain that as long as you subsequently go back for the second dose when called


  • Registered Users, Registered Users 2 Posts: 26,578 ✭✭✭✭Turtwig


    Hardyn wrote: »
    For anybody wondering where it began. Just shows how ridiculously easy it is to spread misinformation. WHO did correct the record but not before the horse was long gone.

    https://twitter.com/ronlondoncon/status/1391895711982264326?s=19

    I'm all for free speech except for Eric Feigl Ding. He needs to be censured. Constantly spouting alarmist misleading harmful shyte!


  • Registered Users, Registered Users 2 Posts: 26,578 ✭✭✭✭Turtwig


    revelman wrote: »
    I’m no scientist or statistician but the numbers we are talking about are so small (22 women and 6 men out of nearly 9 million), how can we be sure that women are more at risk?

    It's not known yet if the vaccine puts women at more risk than men. The matter is complicated further by younger women normally being about three times more likely to experience CVST than men.


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  • Registered Users, Registered Users 2 Posts: 15,450 ✭✭✭✭stephenjmcd


    Don't think it'll be that quick to be honest. Maybe towards the end of next week.

    There's still alot of 50s to & some 60s in certain centres do before thinking about 40s. Mother is 58 and registered on the day so hopefully should hear in the next day or two with an appointment.

    I wouldn't expect 40s to be invited to register though before the next of next week

    Well that was quicker than I thought.

    Mum just got her text, appointment for tomorrow in Greystones, Pfizer is what's assigned to her.

    58 & just under 2 weeks from registering to jab


  • Registered Users, Registered Users 2 Posts: 3,131 ✭✭✭dominatinMC


    Turtwig wrote: »
    I'm all for free speech except for Eric Feigl Ding. He needs to be censured. Constantly spouting alarmist misleading harmful shyte!
    Just about to say the same thing! The man is a merchant of misery, constantly spouting worst case scenario hypotheticals. If ever a Twitter account needed regulating, people have got banned for less


  • Registered Users, Registered Users 2 Posts: 26,578 ✭✭✭✭Turtwig


    If you look at the chart it clearly shows the rise in cases in areas where Indian variant is known to be circulating amongst the younger more unvaccinated population.

    Same rise not observed in older vaccinated population.

    The chart is nothing to do with reducing variant levels in the UK

    The only reservation I have here is the pattern of cases being a significant majority in younger groups was seen at the beginning of previous waves. Social mobility then lead to infections in older age groups.


  • Posts: 0 [Deleted User]


    Turtwig wrote: »
    The only reservation I have here is the pattern of cases being a significant majority in younger groups was seen at the beginning of previous waves. Social mobility then lead to infections in older age groups.

    You would be more worried if cases didnt skew young when the old are vaccinated


  • Registered Users, Registered Users 2 Posts: 1,006 ✭✭✭revelman


    Germans did 1.35 million vaccines yesterday. This would be equivalent to doing over 80,000 in one day here! Very impressive!


  • Posts: 0 [Deleted User]


    Well that was quicker than I thought.

    Mum just got her text, appointment for tomorrow in Greystones, Pfizer is what's assigned to her.

    58 & just under 2 weeks from registering to jab

    Well its actually 10 days,if it was may 5th she registered
    Texts for parc uí caoimh are coming just 5 days after registering


  • Registered Users, Registered Users 2 Posts: 991 ✭✭✭JPup


    abff wrote: »
    That’s very disappointing news. My wife and I got our first AZ dose almost 4 weeks ago and had booked flights for early August in the expectation that we would be able to travel by then. If it’s pushed back to 16 weeks, we will have to cancel our trip.

    I know that’s a relatively minor issue compared to general health concerns, but it was something to look forward to after enduring 14 months of almost continuous lockdown.

    I wouldn't totally write off your trip just yet. The situation is evolving so quickly that your destination could be in a travel bubble with Ireland by then.

    To be fair, you must have known when you were booking for August that you were taking a chance. I've been working on the assumption that the summer holidays will be in Ireland this year and so have most people I've spoken with.


  • Registered Users, Registered Users 2 Posts: 113 ✭✭SJFly


    revelman wrote: »
    I’m no scientist or statistician but the numbers we are talking about are so small (22 women and 6 men out of nearly 9 million), how can we be sure that women are more at risk?

    https://www.reuters.com/business/healthcare-pharmaceuticals/us-cdc-identifies-28-clotting-cases-after-jj-vaccine-2021-05-12/

    This article has some more data. Women in their 40s, 9.4 per million, women in their 30s, 12.4 per million. The risk to men is much lower. Men overall have a risk of around 1.4 per million. I think the data suggests pretty clearly that women are at greater risk.


  • Registered Users, Registered Users 2 Posts: 3,795 ✭✭✭snotboogie


    revelman wrote: »
    Germans did 1.35 million vaccines yesterday. This would be equivalent to doing over 80,000 in one day here! Very impressive!

    Germany on course to get to 50 vaccines per 100 by the middle of next week. Unbelievable rollout.


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  • Registered Users, Registered Users 2 Posts: 6,627 ✭✭✭Micky 32




This discussion has been closed.
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