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Vaccine Megathread - See OP for threadbans

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  • Registered Users, Registered Users 2 Posts: 1,627 ✭✭✭MerlinSouthDub


    Government considers delay to Pfizer second dose

    https://m.independent.ie/irish-news/government-considers-delay-to-secondpfizer-jab-to-allow-more-people-to-get-first-dose-40309563.html

    This needs to happen, certainly for those under 60.


  • Registered Users, Registered Users 2 Posts: 5,133 ✭✭✭TomOnBoard


    Strazdas wrote: »
    Very.....well over 70% I believe.

    The HSE is reporting that data from England shows efficacy rising to 76% at preventing symptomatic Covid at 12 weeks, rising to 82% when dose 2 is given after the 12 weeks, and reaches full efficacy. Scottish data suggests that 4-5 weeks after the 1st dose, the risk of being admitted to hospital with severe Covid is reduced by 94%.

    Earlier data from the trials is portrayed as AZ reducing symptomatic Covid by 60%, and reducing hospitalisation with severe Covid by 100%.

    https://www2.hse.ie/screening-and-vaccinations/covid-19-vaccine/astrazeneca/immunity.html


  • Registered Users, Registered Users 2 Posts: 32,136 ✭✭✭✭is_that_so


    Here's a piece on how one UK doctor both identified the potential AZ clotting issue and a diagnostic test for it.
    Prof Marie Scully developed a diagnostic test at University College London hospital after seeing rare side-effect in patient


    https://www.theguardian.com/society/2021/apr/13/how-uk-doctor-marie-scully-blood-clotting-link-astrazeneca-covid-jab-university-college-london-hospital


  • Registered Users, Registered Users 2 Posts: 14,394 ✭✭✭✭Professor Moriarty


    Hococop wrote: »
    How protected is someone off the first shot of az considering the potential 16 week wait for the 2nd jab?

    Three weeks after receiving the first dose you will have 76% protection and 100% protection against severe Covid-19.


  • Moderators, Society & Culture Moderators Posts: 9,808 Mod ✭✭✭✭Manach


    Following a large increase in deaths of older people in Italy. New PM Mario Draghi announces by decree today that all vaccines will be prioritized for use on the over 70's. It has been 10 weeks since vaccines were available in Italy and 65% of the over 85's have still not been jabbed. Unbelievable that countries would not give priority to the group where 85% of covid deaths come from.

    I agree. However here, there is a distinct lack of communication to the elderly housebound and their carers about when the housebound vaccination is due with the various state agencies shifting responsibility one to the other.


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  • Registered Users, Registered Users 2 Posts: 11,757 ✭✭✭✭ACitizenErased


    Government considers delay to Pfizer second dose

    https://m.independent.ie/irish-news/government-considers-delay-to-secondpfizer-jab-to-allow-more-people-to-get-first-dose-40309563.html

    This needs to happen, certainly for those under 60.

    Not sure how I feel about this. On the one hand we’d fly through the groups but then is it wrong to go against manufacturers advice?


  • Registered Users, Registered Users 2 Posts: 16,249 ✭✭✭✭iamwhoiam


    ddarcy wrote: »
    This is what the HSE is most likely working on. I’d assume that the MVCs will go to Pfizer do to greater numbers and the GPs get AZ. But it’s a bit of a logistical nightmare.
    I would think the opposite . There are 400k 60-70 so I would think they would be done in MCV’s and Group 4 done after 70-75 in the GP’s


  • Registered Users, Registered Users 2 Posts: 6,278 ✭✭✭brickster69


    Manach wrote: »
    I agree. However here, there is a distinct lack of communication to the elderly housebound and their carers about when the housebound vaccination is due with the various state agencies shifting responsibility one to the other.

    It is unreal honestly. The whole idea of lock downs was to protect the vulnerable and as soon as vaccines come they give them to the Serie A footballers first then 10 weeks laters say " oh maybe we should get the older people sorted now ":eek:

    "if you get on the wrong train, get off at the nearest station, the longer it takes you to get off, the more expensive the return trip will be."



  • Registered Users, Registered Users 2 Posts: 16,012 ✭✭✭✭Goldengirl


    Government considers delay to Pfizer second dose

    https://m.independent.ie/irish-news/government-considers-delay-to-secondpfizer-jab-to-allow-more-people-to-get-first-dose-40309563.html

    This needs to happen, certainly for those under 60.

    Sounds like a plan!


  • Registered Users, Registered Users 2 Posts: 9,236 ✭✭✭lucernarian


    josip wrote: »
    Am I the only one who gets apprehensive about future posting activity when I see this ? :)
    You're not. I think it's very questionable why threads are being merged instead of the short ones locked and linked to post here instead. Some people are posting about rather specific things that aren't really to do with the general topic, maybe the loonies could be confined to a different thread instead of merging them here.


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  • Registered Users, Registered Users 2 Posts: 877 ✭✭✭eoinbn


    Not sure how I feel about this. On the one hand we’d fly through the groups but then is it wrong to go against manufacturers advice?

    I believe Pfizer allow up to 6 weeks. I doubt we will go beyond that. Also might only start after we finish the over 70s.


  • Registered Users, Registered Users 2 Posts: 1,658 ✭✭✭Qrt


    So if they know how to spot the adverse AZ reaction, and there’s treatment for it, why are we waiting around?


  • Registered Users, Registered Users 2 Posts: 5,133 ✭✭✭TomOnBoard


    Not sure how I feel about this. On the one hand we’d fly through the groups but then is it wrong to go against manufacturers advice?

    If, as appears to be the case in the trials already completed, dose 1 give 80+% efficacy after 10+ days, and before dose 2, there is sense in considering this. If the marginal benefit of dose 2 after 21 days is an increase in efficacy from 80+% to 95+%, then, I'd prefer to have every 10 people carrying an 80+% risk reduction, rather than 5 ppl with 80+% and another 5 with 0%. In 21 days time, the 5* 0% ppl would still be at 0%, while the 5* 80+% would be improving marginally to 95%.


  • Registered Users, Registered Users 2 Posts: 16,012 ✭✭✭✭Goldengirl


    is_that_so wrote: »
    Here's a piece on how one UK doctor both identified the potential AZ clotting issue and a diagnostic test for it.




    https://www.theguardian.com/society/2021/apr/13/how-uk-doctor-marie-scully-blood-clotting-link-astrazeneca-covid-jab-university-college-london-hospital

    First investigations into this was in Norway . It was reported on here . But of course the Norwegians were being blamed for being over cautious by UK at that stage .
    Maybe this followed on from that , but at the time the Norwegians were discussing immune responses causing the CVST and antibodies being examined , the MHRA was saying nothing to see here .
    I am pleased for this Dr Scully and that she has identified a diagnostic test , but really , the UK are forever banging their drum and give no credit to any other country or its scientists , especially if European .

    Interesting article though :)


  • Registered Users, Registered Users 2 Posts: 16,012 ✭✭✭✭Goldengirl


    eoinbn wrote: »
    I believe Pfizer allow up to 6 weeks. I doubt we will go beyond that. Also might only start after we finish the over 70s.

    Yes, I doubt that they will mess around with over 70s .


  • Registered Users, Registered Users 2 Posts: 6,077 ✭✭✭KrustyUCC


    Government considers delay to Pfizer second dose

    https://m.independent.ie/irish-news/government-considers-delay-to-secondpfizer-jab-to-allow-more-people-to-get-first-dose-40309563.html

    This needs to happen, certainly for those under 60.

    Good

    The more first doses we can get into people the better for the country


  • Registered Users, Registered Users 2 Posts: 14,014 ✭✭✭✭Corholio


    Seeing bits and pieces about the Valneva vaccine out of France. It's in early testing phase but apparently can be made quickly if passing all requirements. It contains an 'inactive' version of the virus and apparently has had outstanding results in testing so far. They say it could be used very quickly against new variants.


  • Registered Users, Registered Users 2 Posts: 102 ✭✭Neleven


    Johnson and Johnson have announced the suspension of their vaccine due to the finding of 6 cases of CVST in 7 million doses (less than one case per million), following on from the suspension of Astra Zeneca to all but the over 60s for the same reason. A quick google of peer-reviewed sources suggests that the incidence of CVST in the general population, pre-Covid, ranged from 7 per million to 15 per million. According to an article in the Irish Times( April 12th) there were 223 cases of CVST and another clotting issue (SVT) in 34 million AZ doses - a rate of about 6.5 per million.
    I am no scientist, but the figures suggest that in the vaccinated population there is no greater incidence of CVST than would be expected in the unvaccinated population. In fact, in some studies it's considerably lower. Am I missing something?


  • Registered Users, Registered Users 2 Posts: 503 ✭✭✭PaulJoseph22


    Corholio wrote: »
    Seeing bits and pieces about the Valneva vaccine out of France. It's in early testing phase but apparently can be made quickly if passing all requirements. It contains an 'inactive' version of the virus and apparently has had outstanding results in testing so far. They say it could be used very quickly against new variants.

    They said the same about AZ.


  • Registered Users, Registered Users 2 Posts: 1,658 ✭✭✭Qrt


    Is that the one that essentially restarted trials?


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  • Registered Users, Registered Users 2 Posts: 14,014 ✭✭✭✭Corholio


    They said the same about AZ.

    It's a different type of vaccine to the AZ one. It's in early testing as I said, cynicism against everything isn't that healthy.


  • Registered Users, Registered Users 2 Posts: 14,014 ✭✭✭✭Corholio


    Qrt wrote: »
    Is that the one that essentially restarted trials?

    I think they had smaller trials and are now preparing much larger scale trials.


  • Registered Users, Registered Users 2 Posts: 1,658 ✭✭✭Qrt


    Corholio wrote: »
    I think they had smaller trials and are now preparing much larger scale trials.

    Ah yes, I was getting mixed up with the french one, Sanofi/GSK?


  • Registered Users, Registered Users 2 Posts: 1,395 ✭✭✭GazzaL


    I'll take the AstraZeneca, the Johnson & Johnson, the Sputnik, or the Sinovac vaccine. Tens of millions of people in the UK have had the AstraZeneca vaccine without any issue. Get the vaccines flowing ffs.

    The zero risk approach is outrageous, pushed by people who are completely unaffected by the consequences of delaying the vaccine rollout.


  • Administrators, Social & Fun Moderators, Sports Moderators Posts: 78,458 Admin ✭✭✭✭✭Beasty


    Threads merged


  • Registered Users, Registered Users 2 Posts: 2,065 ✭✭✭funnydoggy


    Beasty wrote: »
    Threads merged




    Me nerves :pac:


  • Registered Users, Registered Users 2 Posts: 15,067 ✭✭✭✭Danzy


    funnydoggy wrote: »
    Me nerves :pac:

    Side effects? 😉


  • Registered Users, Registered Users 2 Posts: 15,067 ✭✭✭✭Danzy


    GazzaL wrote: »
    I'll take the AstraZeneca, the Johnson & Johnson, the Sputnik, or the Sinovac vaccine. Tens of millions of people in the UK have had the AstraZeneca vaccine without any issue. Get the vaccines flowing ffs.

    The zero risk approach is outrageous, pushed by people who are completely unaffected by the consequences of delaying the vaccine rollout.

    Completely agree, have reviews but keep vaccination program going while doing it.

    I'm not anti lockdown etc but there isn't enough awareness on the damage done already and the damage done by prolonging.

    There will be many more dead from the delay than the poor unfortunates who get the clot.


  • Registered Users, Registered Users 2 Posts: 15,067 ✭✭✭✭Danzy


    Following a large increase in deaths of older people in Italy. New PM Mario Draghi announces by decree today that all vaccines will be prioritized for use on the over 70's. It has been 10 weeks since vaccines were available in Italy and 65% of the over 85's have still not been jabbed. Unbelievable that countries would not give priority to the group where 85% of covid deaths come from.

    Many places in Germany took Easter off, up to 5 days in some cities.

    Lack of urgency on the continent.


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  • Registered Users, Registered Users 2 Posts: 20,411 ✭✭✭✭Strazdas


    Neleven wrote: »
    Johnson and Johnson have announced the suspension of their vaccine due to the finding of 6 cases of CVST in 7 million doses (less than one case per million), following on from the suspension of Astra Zeneca to all but the over 60s for the same reason. A quick google of peer-reviewed sources suggests that the incidence of CVST in the general population, pre-Covid, ranged from 7 per million to 15 per million. According to an article in the Irish Times( April 12th) there were 223 cases of CVST and another clotting issue (SVT) in 34 million AZ doses - a rate of about 6.5 per million.
    I am no scientist, but the figures suggest that in the vaccinated population there is no greater incidence of CVST than would be expected in the unvaccinated population. In fact, in some studies it's considerably lower. Am I missing something?

    It might be a clever move by Johnson & Johnson to suspend their own vaccine in Europe. It shows they are being responsible and are trying not to get themselves an AstraZeneca type reputation.


This discussion has been closed.
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